Delphinapterus leucas (beluga whale): 111164794
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Entry
111164794 CDS
T05885
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
111164794 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
dle03032
]
111164794 (TOP2B)
03036 Chromosome and associated proteins [BR:
dle03036
]
111164794 (TOP2B)
Enzymes [BR:
dle01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
111164794 (TOP2B)
DNA replication proteins [BR:
dle03032
]
Eukaryotic type
DNA Topoisomerases
111164794 (TOP2B)
Chromosome and associated proteins [BR:
dle03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
111164794 (TOP2B)
Centrosome formation proteins
Centriole proteins
111164794 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
111164794
NCBI-ProteinID:
XP_022410404
UniProt:
A0A2Y9LL62
LinkDB
All DBs
Position
Unknown
AA seq
1620 aa
AA seq
DB search
MAKAGGGGSGAGAGGLGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQL
EHILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDK
NMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTG
GRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQ
PDLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLD
ETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEV
VKKKNKAGVSVKPFQVKNHIWVFINCLIENPSFDSQTKENMTLQPKSFGSKCQLSEKFFK
AASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGRHSLECTLILT
EGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKK
SYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKA
SKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRY
AGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFIN
KELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHG
EQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPA
VDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRML
EGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVL
EPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSM
VLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQ
GKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGP
DFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEV
QEREDVLAGMAGKAIKGKVGKPKVKKLQLEETMPSPFGRRIVPEITAMKADASKKLLKKK
KGDLDTTAVKVEFDEEFSGAQVEGAGEEALIPSAPINKGPKPKREKKEPGTRVRKAPTSS
GKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDD
ADDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKASPEKSSHDKGQD
YGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTEKVPSKTVAAKKGKPSLDT
APKPKRIPKQKKVETVNSDSDSEFGVPKKTTAPKGKGRGAKKRKASGSENEGDYNPGRKT
SRTSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEDDVDFAMFN
NT seq
4863 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcagcggcgcgggagctggcggcctcggggcgctgacc
tgggtgactctttttgatcagaacaatgctgcaaaaaaagaagagtcagaaactgcaaac
aaaaatgattcttcaaagaagttgtctgtcgagagagtgtatcagaaaaagacacaactt
gaacatattctccttcgtcctgatacatacattgggtcggtggagccattgacacagctc
atgtgggtgtatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccgggt
ttatataagatctttgatgaaattttggttaatgcagctgacaataaacagagggataag
aacatgacctgtattaaagtttctattgatcctgaatctaacattataagcatctggaat
aatgggaaaggcattccggtagtagaacacaaagtagagaaagtttatgttcctgcatta
atttttggacagcttttaacatccagtaactatgacgatgatgagaaaaaagtaacaggt
ggtcgcaatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaa
actgcttgcaaagaatacaaacatagttttaagcagacatggatgaataatatgatgaag
acttctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattccaa
ccagatctgtccaagtttaagatggagaaacttgacaaggacattgtggctctcatgacc
agaagagcttacgatttggctggttcgtgcaaaggagtcaaggttatgtttaatggaaag
aaattgcctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaagttggat
gaaactggagtggccctaaaagttattcatgaacttgcaaatgaaagatgggatgtttgt
ctcacactgagtgaaaaaggattccagcaaatcagctttgtaaatagcattgcaacaaca
aaaggtggacggcatgtggattatgtagtagaccaagttgttggtaaactgattgaagta
gttaagaaaaagaacaaagctggtgtgtcagtgaaaccatttcaagtgaaaaaccatata
tgggtttttattaactgccttatcgaaaatccaagttttgattctcagactaaggaaaac
atgactttgcagcccaaaagttttggatccaaatgccaactgtcagaaaagttttttaaa
gcagcctctaactgtggcattgtggaaagtatcctgaactgggtgaaatttaaggctcag
acgcagctgaacaagaagtgttcatcagtaaagtacagtaaaatcaaaggtattcccaaa
ctggacgatgctaatgatgctggtggcaggcactccctggagtgcacgctgatactgacg
gaaggggactctgctaagtcgctggccgtgtccggactgggcgtgattggcagggacagg
tacggggtcttccccctcaggggcaagatcctcaacgtgcgggaggcctctcacaagcag
atcatggagaatgcagaaataaacaatatcattaagatagttggtctacaatacaagaaa
agttatgatgatgcagaatcgctgaaaaccttacgctatgggaagattatgatcatgact
gatcaggatcaagatggttctcacataaaaggcttgcttattaatttcatccatcacaat
tggccatcacttttgaagcatggttttcttgaagagttcattactcctatcgtaaaggca
agcaaaaataagcaggaactttccttctatagtattcctgaatttgatgagtggaaaaaa
catatagaaaaccagaaagcctggaaaataaaatactacaaagggttgggtaccagtaca
gctaaggaagccaaggaatattttgctgatatggaaaggcaccgcatcttatttagatat
gctggtcctgaagatgatgctgccattaccttggcattcagtaagaagaagatcgatgac
agaaaagaatggttaacaaattttatggaagatcggagacagcgtaggttacatggctta
ccagagcaatttttatatggtacagcaacaaagcatttgacttacaatgatttcatcaac
aaggaattgattctcttctcaaactcagacaatgaaaggtctataccatctcttgttgat
ggctttaaaccaggccaacgaaaagttttatttacctgtttcaagaggaatgataaacgc
gaagtaaaagttgcacagttggctggatctgttgccgagatgtctgcttatcatcatgga
gaacaagcactgatgatgactatcgtgaacttggctcagaactttgtggggagtaacaac
attaacttgcttcagcccatcggtcagtttggaactcggcttcacgggggcaaagatgct
gcaagtcctcgttacattttcacgatgttaagctctttggcaagactgcttttccctgct
gtggacgacaacctgcttaaattcctttatgatgataatcaacgcgtagagcctgagtgg
tatattcccataatccccatggttttaataaatggtgctgagggcatcggcacaggatgg
gcttgtaaactacccaactatgatgctagggagattgtgaacaacgtcagacggatgctg
gaaggcttggatcctcatcccatgcttccaaactacaaaaactttaaaggaacaatccaa
gaacttggtcaaaaccaatatgcagtcagtggtgaaatatttgtggtggatagaaacaca
gtggagattacagagcttcccgttagaacttggacacaggtatacaaagaacaggtttta
gaacctatgctaaatggaacagataaaacaccagcattaatttctgattataaagaatac
catactgatacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagca
gaagctgctggattgcacaaagtttttaaacttcaaactactcttacttgtaattccatg
gtactctttgatcatatgggatgtctgaagaagtatgaaactgtgcaagacattttgaaa
gaattctttgatttacgattaagctattatggtttacgtaaggagtggcttgtaggaatg
ctgggagcagaatctacaaagcttaacaatcaagcccgtttcattttagagaagatacaa
gggaagattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga
ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag
gaagaaacacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccct
gattttaattatattttaaatatgtctctatggtctcttactaaagaaaaagttgaagaa
ctgattaaacagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctcct
tcagatctttggaaagaagatttagcagcttttgttgaagaactggataaagtggaagtg
caagaacgagaagatgttctggctgggatggctggaaaagcaataaaagggaaagttggc
aaacctaaggtgaagaagcttcaactggaagagacaatgccctcacctttcgggagaaga
atagttcctgaaattactgccatgaaggcagatgccagtaagaagttgctgaagaagaaa
aagggtgatctcgataccacagcagtgaaagtggaatttgatgaagaattcagtggtgca
caagtagaaggtgcaggagaagaggcattgatcccgtcagctcctataaataaaggtccc
aaacccaaaagggagaaaaaggagcctggtaccagggtgagaaaagcacctacatcatct
ggtaaacccagcgcaaagaaagtgaagaaacggaatccttggtcagacgatgaatccaag
tcagaaagtgatttggaagaaacagaacctgtggttattccacgagattctttacttagg
agagcggctgctgaaaggcctaagtacacatttgatttctcagaagaagaggacgacgat
gctgatgacgacgatgacaataatgatttagaggaattgaaagttaaagcatctcccata
acaaatgatggagaagatgaatttgtcccttcagacggcctagataaagatgaatatacg
ttttcaccaggcaaatccaaagctagtccagaaaagtcttcccatgacaaaggtcaggat
tacgggaatctcttctcatttccttcatactctcagaagtcagaagatgattcagctaaa
tttgacagtaatgaagaagattctgcctctgtcttttcaccatcatttggtctgaaacaa
acagaaaaagttccaagtaaaacagtagctgctaagaagggaaaaccatctttagataca
gcccccaagcccaagagaattcccaaacagaagaaagtagagactgtaaactctgactcg
gattccgaatttggcgttccaaagaagacaacagcacccaaaggtaaaggccgaggggca
aagaagaggaaagcatctggctctgaaaacgaaggtgattataaccctggcaggaaaacc
tctagaacaagcaagaaaccgaagaaaacatctttcgatcaggattcagatgtggacatc
ttcccatcagacttcacttctgaaccaccttctctgccgcggaccggccgggctaggaaa
gaagtaaaatattttgcagagtctgatgaagaagatgatgttgattttgcgatgttcaat
tag
DBGET
integrated database retrieval system
