Delphinapterus leucas (beluga whale): 111166300
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Entry
111166300 CDS
T05885
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle01521
EGFR tyrosine kinase inhibitor resistance
dle01522
Endocrine resistance
dle01524
Platinum drug resistance
dle04010
MAPK signaling pathway
dle04012
ErbB signaling pathway
dle04020
Calcium signaling pathway
dle04066
HIF-1 signaling pathway
dle04151
PI3K-Akt signaling pathway
dle04510
Focal adhesion
dle04518
Integrin signaling
dle04519
Cadherin signaling
dle04520
Adherens junction
dle04530
Tight junction
dle05200
Pathways in cancer
dle05205
Proteoglycans in cancer
dle05206
MicroRNAs in cancer
dle05212
Pancreatic cancer
dle05213
Endometrial cancer
dle05215
Prostate cancer
dle05219
Bladder cancer
dle05223
Non-small cell lung cancer
dle05224
Breast cancer
dle05226
Gastric cancer
dle05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111166300 (ERBB2)
04012 ErbB signaling pathway
111166300 (ERBB2)
04066 HIF-1 signaling pathway
111166300 (ERBB2)
04020 Calcium signaling pathway
111166300 (ERBB2)
04151 PI3K-Akt signaling pathway
111166300 (ERBB2)
09133 Signaling molecules and interaction
04518 Integrin signaling
111166300 (ERBB2)
04519 Cadherin signaling
111166300 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
111166300 (ERBB2)
04520 Adherens junction
111166300 (ERBB2)
04530 Tight junction
111166300 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111166300 (ERBB2)
05206 MicroRNAs in cancer
111166300 (ERBB2)
05205 Proteoglycans in cancer
111166300 (ERBB2)
05230 Central carbon metabolism in cancer
111166300 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
111166300 (ERBB2)
05226 Gastric cancer
111166300 (ERBB2)
05219 Bladder cancer
111166300 (ERBB2)
05215 Prostate cancer
111166300 (ERBB2)
05213 Endometrial cancer
111166300 (ERBB2)
05224 Breast cancer
111166300 (ERBB2)
05223 Non-small cell lung cancer
111166300 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111166300 (ERBB2)
01524 Platinum drug resistance
111166300 (ERBB2)
01522 Endocrine resistance
111166300 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dle01001
]
111166300 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
dle04147
]
111166300 (ERBB2)
04090 CD molecules [BR:
dle04090
]
111166300 (ERBB2)
Enzymes [BR:
dle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
111166300 (ERBB2)
Protein kinases [BR:
dle01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
111166300 (ERBB2)
Exosome [BR:
dle04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
111166300 (ERBB2)
CD molecules [BR:
dle04090
]
Proteins
111166300 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
111166300
NCBI-ProteinID:
XP_022413562
UniProt:
A0A2Y9M2S5
LinkDB
All DBs
Position
Unknown
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGDAGTQVCTGTDMKLRLPASPNTHLDMLRHLYQGCQVVQGNL
ELTYLPANASLSFLQEIQEVQGYVLIAHNQVSQVPLQRLRIVRGTQLFEDNYALAVLDNG
GLLESATPAARAAPGGLQELQLRSLTEILKGGVSIQRNPQLCHQDTIVWKDIFHRNNQLA
LMLIDTNRSRACPPCSPACKAPHCWGESSKDCQSLTRTVCASGCARCKGPQPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTTCP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFEGDRASNTAPLQPEQLRVFESLEEITGYLYISAWPDSLP
DLHVFQNLRVIRGRVLHDGAYSLTLQGLGIRWLGLRSLRELGSGLALIHRNARLCFVHTV
PWDQLFRNPHQALLHSANRPEVECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQQC
VEECRVLQGLPREYVKDRYCLPCHPECQPQNGSVTCFGSEADQCVACTHYKDPPFCVARC
PSGVKPDLSFMPIWKFPDEEGMCQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
ILLVVVVGLVFGILVKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPTSPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGSGGTAHRRHRSTSTRSGGGELTLGLEPSEEEPPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQNLPQHDSSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVRPQPPSPLEGPRPPPRPAGSTLERPKTLSPGKNGVVKDIFAFGAAVENPEYLAPR
GRAAPQSHSSPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDMPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagac
gcgggcacccaagtgtgcactggcacagacatgaagctgcggctgccggccagtcccaac
acccacctggacatgctccgccacctctaccagggctgtcaggtggtgcagggtaacctg
gagctcacctacctgcccgctaatgctagcctctccttcctgcaggagatccaggaggtg
cagggctacgtgctcatcgctcacaaccaagtgagtcaggtccccctgcagaggctgcgg
atcgtgcgaggcacccagctgtttgaggacaactatgccctggccgtgctggacaacgga
ggccttctggaaagtgccacccctgctgcacgcgctgctccgggagggctgcaggagctg
cagctgcgaagcctcacagagatcctgaagggaggggtctcgatccagcggaacccccag
ctctgccaccaggacacgattgtgtggaaggacatcttccacaggaacaaccagctggcc
ctcatgctgatagacaccaaccgctcacgggcctgcccaccctgttctccagcttgtaaa
gctccccactgctggggagaaagttccaaggactgtcagagcttgacgcgaaccgtctgt
gccagcggctgtgcccgctgtaagggcccgcagcccaccgactgctgccacgagcagtgt
gctgctggctgcacgggccccaagcactctgactgtctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagctctggtcacctacaacacggacaccttcgag
tccatgcccaaccccgagggccgttataccttcggcgccagctgcgtgaccacctgtcct
tacaactacctgtccacggacgtgggatcctgcaccctggtttgtcccctgaacaaccaa
gaggtgacagctgaggatggaacccagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctatggtctgggcatggaacacctgcgggaggtgagggcggtcaccagtgccaac
atccaggagtttgctggctgcaagaagatctttgggagcctggcgtttctgccggagagc
tttgagggggaccgagcctccaacactgcccccctacagcctgagcagctcagagtattt
gagtctctggaggagatcacaggttacctgtacatctcagcgtggccagacagcctgccg
gacctccacgtcttccagaatctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcgctgaccctgcaagggctgggcatccgctggctggggctgcgctcgctgcgggaa
ctgggcagtgggctggccctcatccaccgcaacgcccgcctctgctttgtacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctccacagtgccaaccggcca
gaggtcgagtgcgtgggcgagggcctggcctgctacccgctgtgtgcccacgggcactgc
tggggtccagggcccacccagtgcgtcaactgcagccagttccttcggggccagcagtgc
gtggaagaatgccgagtactgcaggggctcccccgggagtacgtgaaggacaggtactgt
cttccgtgccaccccgagtgtcagccccagaatggctcagtgacctgctttggctcggag
gctgaccagtgtgtggcttgcacccactacaaggatcctcccttctgcgtggctcgctgc
cccagtggtgtgaagcctgacctctccttcatgcccatctggaagttcccagatgaggag
ggcatgtgccagccatgccccatcaactgcacccactcctgtgtggacctggatgacaag
ggctgccccgctgagcagagagccagccctgtgacgtccatcattgccgctgtggtgggc
attctgctggtcgtcgtcgtggggctggtcttcggcatcctcgtcaagcggcggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggagacagagctggtggagcccctg
acaccgagcggagccatgccaaatcaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggtaccgtctacaagggcatctggatc
cccgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatcc
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggccggtgtagggtcccca
tatgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcctagaccacgtccgggagcaccgcgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggatgtgcgg
ctcgtgcacagggacctggctgcccggaatgtgctggtcaagagtcccaaccatgtcaag
attacagactttgggctggctcggctgctggacattgatgagacagagtaccatgcggat
gggggcaaggtgcccatcaagtggatggcgttggagtccattctccgccggcggttcacc
caccagagtgatgtgtggagctatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctcctggagaagggggaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgtcggccaaggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaagacttgggccctaccagccccttg
gacagcaccttctaccgctcactgctggaggatgatgacatgggggacctggtggatgct
gaggagtacctggtaccccagcaaggcttcttctgcccagaccctgccccgggctctggg
ggcacagcccaccgcaggcaccgcagcacatccaccaggagtggcggtggtgagctgacg
ctgggtctggagccctcggaggaggagccccccaggtctccactggcaccttccgaaggg
gctggctctgatgtgtttgacggcgacttgggaatgggggcagccaaggggctgcagaac
ctcccccaacatgactccagccctctacagcggtacagcgaggaccccacagtaccgctt
cctcccgagaccgatggctacgttgcccccctgacctgcagcccccagcccgaatacgtg
aaccagccagaggttcggccacagcccccctcacccctagagggtcctcggcctcctcct
cgacctgccggttccactctggaaaggcccaagactctctcccctgggaagaatggggtt
gtcaaagacatttttgcctttggggctgccgtggagaaccccgagtacttggcaccccgg
ggcagggctgcccctcagtcccactcttctccggccttcagcccagcctttgacaacctc
tattactgggaccaggacccatcagagcggggatctccacccagcacctttgaagggacc
cctacggcagagaaccctgagtacctgggtctggacatgccagtatga
DBGET
integrated database retrieval system
