KEGG   Delphinapterus leucas (beluga whale): 111167695
Entry
111167695         CDS       T05885                                 
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
  KO
K18438  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle00230  Purine metabolism
dle01100  Metabolic pathways
dle04024  cAMP signaling pathway
dle05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:dle00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    111167695 (PDE10A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    111167695 (PDE10A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    111167695 (PDE10A)
Enzymes [BR:dle01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     111167695 (PDE10A)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     111167695 (PDE10A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 SpoVT_C HD DUF7334
Other DBs
NCBI-GeneID: 111167695
NCBI-ProteinID: XP_022416525
UniProt: A0A2Y9M466
LinkDB
Position
Unknown
AA seq 943 aa
MDRSSLVPRALSAAFPETPRWTRGKEECHTPLRVVCSFSGEISAKGRLPHASGICLPSGA
EASVLGEVMNLGHLGSLATCCAQFSMEPWTHGAPGPPAFSFFSLCFFSLFPVCELEAESR
QALRILRRCLPFTLKSGSKGPALLTLRSRPDTQEQMSNDPAEGSLDSCDATGLTDEKVKA
YLSLHPQVLDEFVSESVSAETVEKWLKRKNNKPEDESSPKEVSRYQDTNMQGVVYELNSY
IEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCVFTPPGIKEGKPRLIP
AGPIAQGTTTSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLI
GILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYF
DNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKSKELYSDLFDIGEEKEGKPVFKKTKE
IRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGV
VQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSIC
TSEEWQGLMHFNLPARLCKEIELFHFDIGPFENMWPGIFVYMVHQSCGTACFELEKLCRF
IMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHGLFTELERKGLLIACLCHDLDHRGFS
NSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAII
ATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTAND
IYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQIFPPTEPL
LKACRNNLSQWEKVIRGEESAVWISNPPAAQGTSEKLPVKIDD
NT seq 2832 nt   +upstreamnt  +downstreamnt
atggaccggtcttccttggtgcctagagcgctcagcgcagctttcccggagacccccaga
tggacaagagggaaagaggaatgccacacaccgcttagagttgtctgctccttttcaggg
gagatcagcgcgaaaggcagactgccccacgcctctggaatatgcctgccgagtggagca
gaagcgagtgttcttggagaggtcatgaacttgggccacctgggctcactggcaacttgt
tgtgcgcagttctcaatggagccctggacccacggggctccgggcccgcccgctttttct
tttttttctctttgctttttctctctttttccagtgtgtgaacttgaagcggaaagcaga
caggcgcttcgcatacttcggcgctgcctccccttcacacttaaaagtgggagcaaagga
cccgctttgctgacactgagaagcaggccagacacccaggagcagatgagcaatgaccca
gcagaaggcagcctggactcttgtgatgcaacaggtttgacagatgaaaaagtgaaggca
tatctttctcttcacccccaggtattagatgaatttgtatctgaaagtgttagtgcagag
actgtagaaaaatggctgaagaggaaaaacaacaaaccagaagatgaatcatctcctaag
gaagtcagcaggtatcaagatacaaatatgcagggagttgtatacgaactaaacagctat
atagaacaacggttggatacaggaggagacaaccaactactcctctatgaattgagtagc
atcattaaaattgccacaaaagctgatggatttgcactgtatttccttggagagtgtaat
aatagcctttgtgtgtttaccccacctggaatcaaggaaggaaaacccaggctcatcccc
gctgggcccatcgcccagggcaccaccacctctgcctatgtggccaagtccagaaaaacg
ttgctagtagaagacatccttggggacgaacgatttccaagaggtaccggactggaatca
gggacgcgtatccagtctgttctttgtttgccaattgtcacggcgatcggtgatttgatc
ggcatccttgagctgtaccggcactggggcaaggaagccttctgtctgagtcatcaggag
gttgcaacagcaaatcttgcctgggcttcagtagccatacatcaggttcaggtatgcaga
ggtcttgccaaacaaactgaattgaatgactttctgctcgacgtatcaaaaacgtatttt
gataacatagttgcaatagattctctacttgaacacataatgatatatgcaaaaaacctg
gtgaatgccgatcgttgtgcgcttttccaggtagaccataagagcaaggagttatattcg
gacctttttgatatcggagaggaaaaggaaggaaaacctgtcttcaagaagaccaaagaa
ataagattttcaattgagaaaggaattgctggtcaagtagcaagaacaggggaagtcctg
aacattccagatgcctatgctgacccacgctttaacagagaggtggacctgtacacaggc
tacacgacccggaacatcctgtgcatgcccatcgtgagtcggggcagcgtgataggcgtg
gtgcagatggtgaacaaaatcagcggtagtgccttctctaagacggacgaaaacaacttc
aagatgtttgctgtcttttgtgctttagccttacactgtgccaatatgtatcatagaatt
cgtcattcggagtgcatttaccgggtcaccatggagaagctgtcctatcatagcatttgt
acttcagaggaatggcaaggcctcatgcatttcaaccttcccgcccgtctttgcaaagaa
attgaactgttccactttgacatcggtccctttgaaaacatgtggcctggaattttcgtc
tacatggtccaccagtcctgtgggacagcctgctttgagcttgaaaagttgtgtcgtttt
atcatgtctgtgaagaaaaactatcgtcgggtcccttaccacaactggaagcacgcggtc
acggtggcacactgcatgtacgccatactccagaacaaccacgggctcttcaccgaactc
gagcgcaagggactgctaattgcgtgtctgtgccatgacctggaccacaggggcttcagt
aacagctacctgcagaaattcgaccaccccctcgcagcactatactccacgtcgaccatg
gaacagcatcacttctcccagaccgtttccatccttcagttggaggggcacaatatcttc
tccaccctgagctccagtgaatatgagcaggtgcttgagatcatccgcaaagccatcatt
gccacagacctcgcgttatacttcggaaacaggaagcagttggaagagatgtaccagacc
ggatcgctaaaccttaataatcaatcacatagagaccgtgtcattggtttgatgatgact
gcctgtgatctttgttctgtgacaaagctgtggccagtaacaaaattgacggcaaatgat
atatacgcagaattctgggctgagggtgatgaaatgaagaagctgggaatacagcctatt
cccatgatggacagagacaagaaggacgaagtcccacaaggccagcttggattctacaat
gccgtggccattccctgctacaccacgctcacccagatcttcccgcccacagagcctctc
ctgaaagcctgcaggaataacctgagccagtgggagaaggtgattcgaggggaggagagt
gccgtgtggatctcgaacccgccggcggcccaggggacctcggagaagctgcccgtgaag
atcgatgactga

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