Delphinapterus leucas (beluga whale): 111173075 Help Entry 111173075         CDS       T05885                                  Symbol SYNE2 Name (RefSeq) nesprin-2 isoform X1   KO K19346   nesprin-2 Organism dle  Delphinapterus leucas (beluga whale) Pathway dle04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:dle00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     111173075 (SYNE2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:dle03036]     111173075 (SYNE2) Chromosome and associated proteins [BR:dle03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     111173075 (SYNE2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  CH Spectrin_SYNE1 KASH Spectrin SYNE1 CAMSAP_CH Ubiquitin_IARS1 Motif Other DBs NCBI-GeneID:  111173075 NCBI-ProteinID:  XP_022426101 UniProt:  A0A2Y9MUL0 LinkDB All DBs Position Unknown AA seq 6919 aa AA seqDB search MASGPVLPTEDEQVSLGIDDLHFSLQAEQEDTQKKTFTCWINSQLAKHTPPSVVSDLFAD IKKGHVLLDLLEVLSGQQLPRDKGSNTFQCRSNIEHALRFLKNRSIKLINIHVTDIIDGN PSIILGLIWTIILHFHIEELARTLSCNYNQPSLDSVSVVDSSPTSSPPAKKCSKVQERWQ MSAKKALLQWAQEQCAMFESVSVTDFKASWRNGMAFLAVIHGLRPDLIDMKSVKHRSNRD NLKEAFRIAERELKIPKMLEPEDVDVVNPDEKSIMTYVAQFLQYSKAAPGTGDKAQGKVK DAKVWLTLQEKKLQKMLTDSENETYCNKYESLLSFLESFNEEKKPFLDVLSITRNLDELN EDQLQLREAWDGLNYQINVWKTELNHVLPSPLYQIETWLLGVEELIDEDLPASQDYYEAM ALIQEKMTLFQSLMDKFDCHLNTLLTFENRDEKYLPLVPPNKLEEMKRRINNISGEKFIP LLEFHYYKCSVLGLLDEVKSKLVVWNIKYGSKESVELLLEDWHKFIEEKEFLAQLETSFQ KCEEIHKNLAGQYPNISKQYTMVEYHFCMYRKNIYNVKSTLQKVLACWTIYVEKLRLLKA CFEETKKEQMKEVPFETLSQWNLEHTTLNEVGNFLIQVSNDEVGSSISKELRRLNKRWRK FITKTQLEMNLPLIKKQDEPFLDNSGNTQLSKEANLTADFSTDMSIELPENHSQNIMAGE EHEKENEEFTGTLKVAEEVEKLIGQVKIWEAETTSVLDLLRQQGDVDTSVEESLQHLIAK GSMYEELVSRTEDTLQMDVQNVSSQESLQHVITAGLQAKIQEAKEKVQINMVKLVAVLKN STDVSPDLDVRLKVEDSQKELESYITRAEQLLGQRESQRGLISKYKEALIIFNTKSLAKY LKAVEELKNNVTEDVKLSLEEKSRDICAKWESLHHEMSLYIQQLTIDIEKEKLSDNIAKL EKQINKEKKLIRRGRTKDLIKQHEACFSEESSLYQLDHHMDVLRELCEELTSQKSQQEVR RALKDYEQKIERLRKCASEIHMTLQPTVGGTSKNKGTSDTSENGGRNALSEVPSAKSDSQ PSAEKAMESIKDFSLESKLKPQQEESIMEKYEKDHSASINSLLERYDTHRDNLELHLQNN IVRIISDFSSDKERSSVCLQDKLTDLQVLKNETEACWKEFEVTSLKLEELESDIRKPFLV KARDKLKEKERELQMTLNTRMESLETALHIVLPVEKELLLLCDSDLLLCEMAIQEFNLTD ADDIYRNLRNIQDSIVRQIEICNHLEQSGNFALKELHPLDLHAAQNIILKHRTQLEEMNH RVQRSKDAVKALEDFLASLRAAELTGELLIDLSASGSQVVPGNTLTVENKEERIHQMKDK ARHLDERLKVLGISIKDAEWGENTSCEKLLNALSRSLSETHGSGRQEEIMEEDELLETCI FKNNELLKNIQDIHYQISKIGLKDPTVPAVKQRKKSLLRLDKDLDECEEEKKHLQEMVSS LPQFKDGREKALSQQCQGTALLWENTKASVTECLDQCERVLELLKQYQNFKSVLTTLIQK EENIISLQASYMGKENLKKRIAEIEVVKEEFNEHLEVVDKINQICKNLQFHLNKMRNFEE PPFEKEANIIVDRWLDINEKTEDYYENLGRALALWDKLFNLKNGIDEWTEKILQKMELHQ LTEEERQKLKEELQVHEQKPSEFSKRVAKIQFLLQSSEIPLELQVMESSILNKIEHVKMR LTGESYCSALGGSTAELREDLDQAKTQIGMTESLLNALSPSDSLEIFTKLEEIQQQILQQ KHSMILLENQIGCLTPELSELKKQYESVSDLFNTKKSVLQDHFSKLLNDQCKNFNDWFGN VKVNLKECFEPPETKKSVEQKLQKLSDFLTLEGRGSEIQQVGTVLNHVKKHLPKAPVKKL NSWIVSQEIELEKMESICQARAKELDECLPQLLRLQNDHRNLSKWLTNQEEKWKEMEGTR EKTELFCQALARKREQFESMAQLNNSVKEYGITEEEEIVTESTHLINRYQTLLGQLCEID EEDKLPPAKDQSFNDLAHDVIRWITGIKESLMVLNSSEGKMPLEERIQKIKEIILLKPEG DAKIQTVVSQAESSKAPMVPKTLTDIKNQWDNTLHLANTYLSHQEKLLLEGEKYLQSKED LRLMLTELKKKQEVGFALQHGLQEKKAQLKIYKKFLQKAQDLTSLLEELKSQGNYLLECT KNPNFSEEPWLEIKHLHESLLQQLQDSVQKLEGHVQEHDSYQVCITDLNTALDYISKEFV GFSDKPVDQIAVEEKMQKLQELENSLRLQDGTLEKILALAKSIKQNTSSVGQKIIKDDIK SLKCKQKDLENRLESAKQEMDNCLNSILKSKCSTEKREKFPLPGREEQVTSDVQESAEDS AAVEKLEEDWEINKNSAVEMVLSKQLSPDVQESMKTTEDEQKVNELQNQPLELDVMLRNE QLKEIEELCTQLEAKKAAIEPLEQIEYLKKAETSALFPHSERYSVQHLDNLLQALTTLKK KKESQYCLLKDFQEHLVAVESSMKALLTEKESLKVGPLDSATHTDKIKKLLASIEKEKDS LSKLKIEWENLSNCLTDMDKKLLESQMKQLEHGWEQMEQLVQKKYSQQVVGHDEFTFLMS KIQDLEISLQQQQQCLQLRLDSPEEEGNQSMVALATELQTIKHRFSVFRGRAELQMKRIW GEKEKKILGDAINNLQKQLEALEPLNIEVENQIKKCETRYKMKEAILWVKNLLGELVPTI SLLPDNILSQIRKCKVVHDGILDKQQVVESLVEEVKDNIPNLTAYESSDLNNLLQDLQNQ YQMLVLKSTQRSQQLEFNLEERSKFVGVIGKVQLSLQGNETLMIPKMQTTSTEAELEHQY VTLTISQKELQEIESVIATHLQEQTNICKDLSVFERLFLDDQLKNLKTRANRTQRFIQNK CNEVEHKINFYREFYGKTSELQKEVDHIQHNELLLNPEINPDVKEELYRLRDQITGIRSS ILQVLKLKEVFDCIGINWDWSQLDQLQTQILEKEKELEEKIKQLDTFVAEYGKYQASLGK LRAMDLQVKKRTEALLTTPNTPPESSLLNAQILNQRIRKVMCLYHEIIKKLSENKDFDDS FKEKEMLQIKLYAEESDKLHKVLQNIVLESQPKEMDEKNFQDKLENSLHVLNHIKSQLRQ PLLINLQIEHIQNEKVNCEMFQEQVQAELDSIKAVTVLEKQREENSSEASDVETKLHDIE DLYMQLNASIDSRTNVLNDAYGNMARYNEAVSRAMGIITALEAIIASHRVDLDNPEESIE MPRRKQEELKSTIADIQDLTENLGTICSPEAKRQLECTLQELVSKDSAMREAAKVKEAEV ERCLENYKGYRKIKEKICTNLSQMETVLGQSMSPLPMSYKEALERLEQSKALVSNLMSTK GELMKVRQVLRHLRPMCTDSDSLCLLRSTSALWERWLSLMEAVKEWELWCEELKQEWKFI HEEIEREGIILDNLQEELPEISKTKEAATTEEFSELLDCLCQYEENVERQQLLLALLLQR VKNIQNTPEGLRPMGTVSASQEIMSMQERCHKLFQKAQKNKELIQNEIQERHAFTKEIIT LKNSFQQTTTFFQNMELQDHPEKAEQLEELQSILKKGKLTFENIMEKLRIKYSEMYTIVP AEIESQVEECRKALEDVDEKISNEVLKSSPSYSMSRKIDEINNGLRNVEKMLQQKSKNIE KAQEIQKTMWDELDLWHSKLNELDSEVQDIVEQDPGQAQEWMDNLMIPFQQYQQVSQRAE YRTSQLNKATIKLEEYHDLLKSTEAWIENTSRLLADPADYDSSKTLSHHASTLQMALEDA EQKHNLLHSIFMDLEGLSIIFETDTLAQPIQDLSHHIVALRQKIIESLPQIQRMADDVVA IETEVKSMEKRVSKIKAILLSKEIFDFSPEEHLKHGEVILENIHPMKKTIAEIVSYQVEL RLPQTGMKPLPVFQRTDELLQDIKLLENVTQEQNELLKIVIKQTNECDEEIEKLKQILNN YSAEFSHEHMSPDRAANLPQVQGEIEGTEKQILSLNQRKEDLLVDLKAAVLKLHQHFQQK QQELEEEMLSARASDEDGGAERDASEWKLNRTGSMFFLPAVEEEVEESSLKSESGDKKAE PPSRSPSLLWKHDKDVEEDRTSSSSGTMVQEAAWKISMCDSSTAQIFAQDSLNTEQGPEF SLSPNQTQEGTTPPIKVAALGFSDEQGAFEATVEKARPKPAEVLHVCKNQVAELELWLQQ ANVAFEPETLDADMQQVVEQQLVGCQAMLTEIEHKVASLLENCKDQGLGDSGATQQEAEA LSLKLKTVKCNLEKVQMMLQEKYSENQHSTMLKKSSEHQKVLQPDNLSEFESVVTERPQF SRQKDFQQQQVLELKPMEQKDLIKFIEFNANKIWPQYRQHDKDTTQPSSVSSKASSPEND APDLILSTQGQSGDKWQYLHHELSSKIRLPLPQPVQPQVATNMSVLPSVSIYNFRYPTTE ELKTYTTQLEDLRQEANNLQTQEDVSEEAYANLDKKLLELFLTLSQCLGSVEEMLQTPWL LRGDVGAQQVHYETLALELKKLCLAMSDKKNDISKAMTWPGKNASLFLDCFDNLQIYLEH IQATTASRSKSLKAGLDYNRSYQNEIKRLYDQLIKNKTSLQQSLNEISGQSIDEQLQKAD AYTVELQNSESRVAKLRDEGERLHLPSVLLQEVYKLEDVLDRMWGILRARYTKLSSPFIT ESQQDALLQGMVELVNIGKENLAHDHLQQTKSKVALQAQIQNHKLFFRKLVADMLLIQTY SNKMLPSLLQKKETVWAEQVKEVKLLEEKSHQCGIKLQSLLQKWEEFDENYASLEKDLEI LVSTLPSVSLVEETEERLMERISFYQQIKRNIDEKHARLYQTVNEGKQLVVSVSCPELEG QIAKLEEQWLSLNKKIDHELHRLQTLLKHLLSYNRDSDQLTKWLESSQQTLNYWKEQSLN VSQDLDTIRSNINNFFEFSKELDEKSSLKTAVLSTGNQLLHLKEADTATLRASLAQFEQK WTMLITQLPDIQEKLHQLQMEKLPSRKAITEMINWMNDVEHQTADEDSEHSLSSASQVKN LLHKYKEFRMEMDYKQWIVDFVNQSLLQLSTCDVESKRYERTEFAEHLGEMNRQWHRVHG TLNGKIQQLEQLLESITENENKIQILNNWMEAQEERLNTLQKPESVISVQKTLLDCQDIE NQLAIKSKALDELRQSYLTSESGTMPLLEDTASRIDELFQKKTSVINQVNELKTSMQSVL QEWKTYDKLYDEVNMMTIRFWYRMEHSKPVVLSLEALRCQVQNLQTLQDEAESSEGSWKK LQEVIGKLKDYCPSVAEIIQEKCQNTHTRWTQVNQDIADQLQRAQSPLQLWKAYNSAHAE AAARLEQQEAKYQQLANINTSGNNLAEILPPALQDVKELQHDVQKTKEAFLQDSTLLDRL PQPAEPNTHVLLSGQMHSLQRASYLEKMLLMKTNEFKFVLSQFKDFGDQLDSLKGLITHE EENLDKLYQQEKEGNPDLFLNHVLALTAQSPDIEHLNEVSLKLPLSDVAVKTLQNVNRQW IRATATALERCSELQGIGLNQKFLYCCEKWVQLLEKIEEMLKVNIADSLPALLEQQKTYE MLEAEVSINQTIADSYVTQCLQLLDTAEIEKRPEFVWKFTRLKERWQSAAQGVRQRKSDI DELVRQWQYFTTSEGDLLHLLAYTSHLLSAVKSQDCYSLHQTRSLIHELKNKEIHFQRWQ TTYALTLEAGGKLLSTTHLETKESIEKRISQLQDTWKDTKLQLGEMIKQFQSTAETWDQC EKKIKELRNRLQVLKAQSKDPLPELHEELHREKELIKELEKSLANWTQNLKELHTMKTDL TQHILVEDVVVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNSWIVFNEKNKELCAWLVQ MENKVLQTADISIEEMIEKLQKDCMEEINLFSENKLQLKQMGDRLIKASNKTRAAEIDDK LNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCD DQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSVQQTTRSLDR RWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLYTVAKEE LKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASKLKQMVHEGNQRWDNLQKRVTA ILRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHFSESDADDKMRQLNGFQQEITL NTNKIDQLIVFGEQLIQKSEPLDAVLIEDELEELHRYCQEVFGRVSRFHRRLTSHASGLE DEKEASENETDVEDPREIQDDSWRKRRESEEPSSPQSLCHLVPPAPGPERSGCETPVSVD SIPLEWDHTGDVGGSSSHEEDEEGPYYSALSDVEIPENPEAYLKMTTKTLKASSGKSISE GHSWHVPDSPPCRKRRYKQMGGDRNVQPIPSDSSTPYKPAYVKLLLSPGTEGGKEDPRVL TGGPQREDEGLAALTGQQSGAFDRWELIQAQELHSKLRIKQNLQQLNSDISDITTWLEKT EAELETLKLAKPPSGMQEMELRVKRLKEILKAFDTYKALVVSVNVSSKEFLQTESTDSEE LQDRVGQLRLRWDAAQGAVESWREGLRLSLMQCQDFHQLSQSLLLWLASAESRRQEARVT DQEADPRPLLACREELLQLEKELVERQPQVNSLQEISSSLLIKGHREDYIEAEEKVHVIE KKLKQLLEQVSQDLVSLQQSQNPDSPLPSLDEADPREPLAAPVPAPQAKQFRAEVTTKDK TKTASRVPSPAGPESSRPQRSFLWRVIRAALPLQLLLLLLLLLACLLPSSEEDYSCTQAN NFARSFYPMLRYTNGPPPT NT seq 20760 nt NT seq  +upstreamnt  +downstreamnt atggcatctggtcctgtgcttcccaccgaagacgaacaggtttccttgggcatcgatgat ctccatttttcattgcaagctgaacaggaagacactcagaagaaaaccttcacatgctgg ataaactcacagttggcaaagcacacccctccctcagttgtatcggacctattcgcagac attaaaaaggggcatgtcctcctggacctgctggaagtactctcaggacaacagttgcct cgagataaaggatctaatacattccagtgtagaagcaatatagaacatgccctgaggttc ctaaaaaaccgatcaatcaagctaataaatattcacgttaccgatattatagatggaaac ccatccattattcttggcctaatttggacaattatactgcactttcatattgaggagctt gcccggactctttcttgcaattacaatcagccttccctggacagtgtgagtgtggtcgac tcatctcctacctcaagtcctccagctaagaaatgctccaaagtccaagaaagatggcag atgtctgcaaagaaggctcttctccagtgggctcaggagcaatgtgccatgtttgagtct gtcagtgtgacagattttaaggcaagctggagaaatgggatggcttttttggctgtcatt catggcttgcgaccagacctgatcgacatgaagagtgtgaagcatagatccaacagagac aatctgaaagaggccttcagaattgcagaaagagaattaaaaatccccaaaatgctggaa ccagaagatgtggatgttgttaatcctgatgaaaagtcaatcatgacctatgtggcacag tttctgcagtattcaaaggctgcacctgggactggagataaagcccagggaaaggtgaaa gatgctaaggtctggttaactctgcaagagaaaaagctacagaaaatgctaacggattca gaaaatgagacctactgtaacaagtatgaaagcctgctgtcctttttggagtcattcaat gaagaaaaaaaaccctttctggatgtcctgtcgataacaaggaatctagatgagctgaat gaagatcagttacagttgagagaagcctgggatggtctcaactaccagattaatgtgtgg aagacagagttgaatcatgtcttgccctcacccctctatcaaatagaaacttggctcctg ggggtggaggagcttatagatgaagatttgccagcctcccaggattattatgaagccatg gctctaatacaagagaaaatgactttattccagagtctgatggataaatttgactgtcat ttgaatactctcctgacatttgaaaatagagatgaaaaatatttgccattggtaccacct aacaaattggaggaaatgaaaagacgaatcaacaacatttcgggggaaaaattcattcca cttctagaatttcattactataagtgctcagttcttggtttgctagatgaagtgaaatca aaattggttgtttggaacatcaaatacgggagcaaagaatctgtggaattattgctggaa gactggcataaatttattgaagaaaaagaattcttagctcaacttgaaacctcttttcaa aaatgtgaagaaattcataagaatttggctggacaatatccaaatattagtaaacaatat acaatggtggaatatcatttttgcatgtatagaaaaaatatatataatgtgaagtccact ctacaaaaagttctggcatgttggacaatttatgtggaaaagcttcgtttactaaaggct tgttttgaggaaacaaagaaggaacagatgaaagaggttccctttgagacactgtcccag tggaatctagaacatactactttaaatgaagtgggaaatttcttaattcaagtcagcaat gatgaagttggatcatctatttctaaagaactgaggaggctgaataaaagatggagaaag tttattacaaaaactcagcttgaaatgaacctgccccttataaaaaagcaagatgagccc tttcttgacaattctggaaatactcaactatctaaagaagcgaacctaactgctgatttt tcaacagatatgtcaatagaacttcctgaaaatcacagtcagaatattatggctggggaa gaacatgaaaaagaaaatgaagaatttacagggacactgaaagtggctgaagaggttgaa aaactgattggacaagtgaaaatctgggaggcagaaaccacatctgttttggatcttctg agacaacaaggtgatgtagatacctcagtggaagaatctttgcagcatcttattgccaaa ggctctatgtatgaagagcttgtgtctagaactgaagacactttacaaatggatgtgcaa aatgtttcaagccaggagtctcttcagcatgtgatcacagctgggcttcaggcaaagatt caagaagctaaagagaaagttcagatcaatatggtaaaattagtagcagtgttgaagaac tcaactgatgtttccccagacctggatgtcaggctgaaggtggaagactcacagaaggaa cttgaatcatacattacaagggctgaacaattacttggccaaagagagagccagagagga ctaatttcaaaatacaaggaagcactaataatttttaatactaaaagtctggccaagtat ttgaaagctgttgaagaattgaaaaataatgtaactgaggatgtaaagctgtctttggaa gaaaagagtagagatatctgtgccaagtgggagtcgcttcatcatgaaatgtctttgtat attcaacaactaacaatagacattgaaaaagaaaaacttagtgacaatattgcaaaactc gaaaaacaaataaataaagaaaagaaactaattcgcagaggaaggaccaaggatctcatc aagcaacatgaggcctgcttttcggaggaaagcagcctgtaccagcttgatcaccacatg gatgtcctgcgggagctgtgtgaagagctgacttcacagaagagtcaacaggaagtgagg agagcgctcaaagattatgaacagaagatagaaaggcttcggaaatgtgcttccgagatt catatgacactgcaacccactgtgggaggcacgtcgaaaaacaagggtacttcagacaca tctgagaatggaggaaggaacgccctcagcgaggttccatctgcaaaatcagacagtcag ccatcagctgaaaaggcaatggaatcgattaaggattttagcctggaatccaagttaaag cctcaacaggaggaaagcattatggagaaatatgaaaaggatcacagtgcatctataaat agtttactagagaggtatgatacacacagagacaatcttgaactacacctgcaaaacaac attgtcaggattatctctgatttctctagtgacaaggaaaggagtagtgtttgtctacag gataaactgacagatctacaggtcttaaaaaatgaaactgaggcttgctggaaagagttt gaagtcacttcactgaagttagaagagctggaaagtgacattaggaagccttttctagtt aaggcaagagataaattaaaggagaaagaaagagagcttcagatgactcttaataccaga atggagtctttggagactgcgctgcatattgtgttacctgtggagaaggagttgctcctt ctctgtgactcagacctgctcctctgtgaaatggccattcaagaatttaatctcactgat gctgatgacatttatcgaaacctgaggaacatccaagattccatagtaagacagattgaa atatgtaatcatttggaacagtcaggcaactttgcgttaaaggaattacacccgcttgac ctgcatgcagcacagaatattatcctgaaacacagaactcaacttgaagaaatgaaccac agagtccagaggagtaaagatgccgtcaaagctctggaagactttttggcttctctgaga gcagctgaactcactggtgagcttcttatagacctttcagcctcaggttcacaggtggta ccaggaaatactttgacggtggaaaataaagaggaaagaattcatcagatgaaagacaag gccagacatttggacgaacgtttgaaggtgctcggtataagcattaaagatgctgaatgg ggtgaaaacacctcctgtgaaaaacttctgaatgctttgtccagaagcttatctgagact catggctctggcagacaggaggaaatcatggaagaagatgaattattagagacttgtatt ttcaaaaataatgaactcctgaaaaatattcaagatatacactatcaaatcagcaaaata ggcctgaaagatccgaccgttccagctgtaaaacaacggaaaaaatcgttactcagacta gataaggatctagatgaatgtgaagaagagaagaaacacttgcaagaaatggtgagttct cttccacaattcaaagacggcagagagaaagctctgagtcaacagtgccaaggcacagca ctcttgtgggagaatacaaaagcttcggtcactgaatgccttgaccaatgtgaaagagtt ttggagctcttaaaacaatatcagaattttaaaagtgtcctgacaactttgattcaaaaa gaagagaatatcatctccctccaggcttcctacatgggaaaggagaacttgaagaaaagg atagcagagattgaagttgttaaagaagaatttaatgaacatttagaagttgtagacaag attaaccagatctgcaaaaatctacaatttcatctaaataaaatgagaaactttgaagag cctccttttgagaaagaggctaatattattgtggataggtggcttgatataaatgagaag acagaagactactacgaaaatcttggtcgagctctagctttatgggacaagctttttaac ttaaaaaatgggattgatgagtggactgaaaagatccttcaaaaaatggaattacatcaa ctgactgaagaggaaagacaaaagctgaaggaagagttacaagttcatgaacaaaaacct tcagaattttctaaaagagtggctaagatacagttcctgcttcaaagcagtgaaatacct cttgaattacaggtcatggagtcctctattttgaacaagatagaacatgtgaaaatgcgt ttaacaggagaatcctactgcagtgcactcggtggcagcacagctgagttaagggaggat ctcgaccaggctaagacccagattggaatgactgagtccctcttaaatgccctgtctcct tctgacagcttggagatctttactaaactagaggagattcaacagcaaattctacagcag aaacacagtatgatattacttgagaatcaaataggttgtctgactcctgaactctctgaa ttaaaaaagcaatatgaaagtgtcagtgatttatttaataccaaaaaaagtgttttgcaa gatcacttctctaagttactgaatgatcagtgcaagaactttaatgactggtttggcaac gttaaagtgaaccttaaggagtgttttgaaccaccagaaacaaaaaagagcgtggaacaa aaactacaaaagctttctgatttcttgactcttgaaggaagaggcagtgaaatacagcag gtgggaactgtactgaatcatgtgaaaaagcatctgcccaaagcacctgttaagaagctt aacagttggatcgtaagtcaagaaattgaattagaaaaaatggagtccatatgccaggca cgagcaaaggagcttgatgagtgcttgccgcagctactgagactccagaatgaccacaga aacctgagtaagtggttgactaatcaagaagagaaatggaaagaaatggaaggaacaaga gagaaaactgagctattttgccaagctctagctagaaagagggaacaattcgaatctatg gcccagttgaacaactctgtgaaggaatatgggattactgaggaagaagaaatagtaaca gaatcaacacatttgatcaatagataccagacattattgggacaattatgtgaaattgac gaagaggataagttacctcctgccaaggaccagagctttaatgatcttgcacatgatgta attcgttggataacagggattaaagagtccctgatggttttgaattcatctgaaggcaaa atgccacttgaggaaagaatccaaaaaataaaggaaatcattttactaaagcctgaaggg gacgctaaaatacagaccgttgtgagtcaggccgagagcagcaaggctccgatggttcca aagacccttactgatatcaaaaaccagtgggacaacacactccacttagccaacacatat ctaagccatcaagaaaagcttctactagaaggcgagaagtatttgcaaagtaaagaggat ctgagattaatgctcacagaactaaaaaagaaacaagaagtgggctttgctctgcaacat ggtttgcaggagaagaaagctcaattaaaaatttataagaaattcctccagaaagcacaa gatttgacatccttactagaggagttaaaatctcaaggaaattacctcttagagtgcact aaaaatcccaactttagtgaagagccgtggctggaaataaagcatctacatgaaagtctt cttcaacagctacaggattctgtgcaaaaattggaaggtcatgttcaagaacacgactca taccaggtttgcatcacagacctaaatactgcattggactatatctccaaggaatttgtc ggtttttctgataagcctgtggatcaaatagcagttgaggaaaaaatgcagaaactgcag gaactagagaatagtctccgtttacaagatggcacattagagaagattttagctttagcg aaatccatcaagcaaaatacatcttcagtgggacagaagattattaaagatgatataaaa tcacttaagtgtaaacaaaaagatttggaaaacagacttgaatctgctaagcaggagatg gacaattgtctcaacagcattctcaaatcaaaatgctcaacagaaaagagagaaaagttt cctctgccaggcagagaggagcaggtcacttctgatgtacaggagtccgctgaggactca gctgcagtggaaaagttggaggaagactgggaaataaataagaattcagctgtggaaatg gtcttgtcaaaacaactttctcctgatgttcaagaaagcatgaaaaccactgaagatgag cagaaagtcaatgagctgcaaaatcaacctttagaattagatgttatgttaagaaatgaa caattaaaagagatagaggaattatgtacccagttggaagcaaagaaagcagccattgaa ccactagaacaaattgaatatcttaagaaagcagaaacaagtgccttgtttccccacagt gaaaggtattcagtgcagcacttggacaatctgcttcaggcacttactactttgaagaaa aagaaagaaagccaatactgtctccttaaagattttcaggaacacctcgtggcagttgaa tcctcgatgaaagccttgttgacagaaaaggaaagtctaaaagtgggaccactggacagt gcaacccatacagacaaaattaaaaaattactggcatcaatagaaaaagagaaagattct ttaagcaagttgaaaatcgaatgggaaaatttatcaaactgtctgactgacatggataag aagctgttggaaagccagatgaagcaacttgaacatggttgggagcaaatggaacaactg gtccagaagaagtattctcagcaagtggtgggacatgatgagtttacgtttctcatgagt aagatccaagaccttgaaatttctctgcagcagcagcagcagtgtctgcagttaaggctg gactctccagaagaagaagggaatcaaagcatggttgccttggccactgaactccagact atcaagcatagattttctgtgttcagagggcgagctgaacttcagatgaagaggatttgg ggagaaaaagaaaagaagattttaggagatgcaataaataatttgcagaagcaattggaa gcattggaaccattaaacatagaggtggaaaatcagatcaagaagtgtgagaccaggtac aagatgaaagaggctatcttatgggtcaaaaatctgttaggtgaactcgtccctaccatt tcccttctcccagacaatattctttcacagatcagaaaatgcaaggtggtgcacgatggc attctagataagcagcaggttgtggagtcattggttgaagaggttaaagataatattcct aaccttacagcatatgagagcagtgatttaaataacctcctacaggacttacagaatcaa taccaaatgctagttttaaaatcaactcaaagatcacagcaattagaatttaacttggaa gaaagaagcaaatttgttggggtaatagggaaggttcaactttcacttcaaggaaatgaa acactgatgatccccaagatgcaaacaacctccacagaagctgaactagaacatcagtat gtcactttgaccatttctcagaaggaattgcaggaaattgagagtgtaatcgcaacacat cttcaggaacaaacaaacatctgtaaagatctaagtgtatttgaaagattatttctagat gatcaattgaaaaatcttaagactagagccaacagaacacaaagattcattcaaaataaa tgtaatgaagtagaacacaagataaatttttatagagaattttatggaaaaacatctgag cttcagaaggaggttgaccatatacagcacaatgaactgctactaaatccagaaataaat ccagatgttaaagaggagttgtatcgtcttagagaccaaatcactggtattcgatctagt atcctacaagtattgaaactcaaagaagtgtttgactgtataggaataaattgggattgg tcccaacttgaccaattacaaacccaaatacttgaaaaagaaaaggaacttgaagaaaaa attaagcagttagatacatttgtggcagaatatggcaaatatcaggcatcactaggtaaa ttgagggctatggatctgcaagttaagaaaaggactgaagcactactaacaacgcctaac accccaccggaaagcagtctgctcaatgctcaaattttgaatcagagaatcaggaaagtc atgtgcttgtatcatgaaataatcaagaaattaagtgaaaataaggactttgatgactca ttcaaagagaaagaaatgctacaaataaagctgtatgcagaagaaagtgataagttacac aaggttctccaaaatatagttctggaatcccaaccgaaagagatggatgaaaagaatttt caggacaaactagaaaattccttacatgttttaaatcacataaaatctcagttacgacag cctttacttataaatttgcaaattgaacatattcaaaatgaaaaagttaattgtgaaatg tttcaagaacaagttcaggcagaactggatagcattaaagctgtgactgttcttgagaag caaagagaagaaaactcttctgaagctagtgatgtggagacaaaattacatgacattgaa gatctttacatgcagcttaatgcaagcattgattcgcgcacaaatgtcttgaatgatgct tatggaaatatggcacgctataatgaagcagtctccagggccatggggatcatcactgcc cttgaagccatcattgcatcccatagagtagaccttgataatccagaagaatcaatagag atgcctcgccgcaaacaagaggaactgaagtccacaatagcagacatccaggacctcacc gagaatttggggactatatgcagcccagaagctaaacgacaacttgagtgtactttacag gaattagtttctaaggactcagccatgagggaggcagccaaagtaaaggaagctgaagta gaaaggtgtcttgaaaattacaaaggctatagaaaaataaaagagaaaatttgcactaac ctcagccagatggagacagttcttgggcagtccatgtccccattgccaatgtcatacaaa gaagctttagagcgcttggaacagagcaaggccttggtgtcaaatcttatgtcaaccaaa ggagagctcatgaaagtacgacaggtcctcagacacttgagacccatgtgcacagatagt gacagcctctgtttactcagaagcacatctgctctatgggagagatggctgagtttgatg gaagctgttaaagaatgggagttgtggtgtgaagaactgaagcaggagtggaaatttatc catgaagaaattgaacgagaaggaattattttagataatcttcaagaagaactccctgaa atttccaaaacaaaagaggcagccaccacagaggaattctcggagctgctggattgttta tgccaatatgaagagaatgtggagaggcagcagctgttactggccctacttctgcagcgc gtaaaaaatatccagaacactcctgaaggcttaagacctatgggaactgtttctgcatct caagagattatgtctatgcaagaacgatgccacaagcttttccagaaggctcaaaaaaat aaggaattgatacagaatgaaatacaagaaagacatgcctttacaaaagaaataattact ttgaagaattcatttcagcagactacaacctttttccaaaatatggaattacaagaccac ccagaaaaggcagaacagcttgaggagcttcaaagcattcttaagaaagggaagctaact tttgagaatattatggaaaaactgcgaatcaagtattctgaaatgtacaccatagtccct gcagagattgaatcccaggtggaagaatgcagaaaagctttagaagacgtagatgagaag atcagcaatgaagtcttgaaaagctcaccatcatattcaatgagtagaaaaatagatgaa attaacaacgggcttcggaatgtcgaaaagatgttgcagcagaagagcaaaaatattgag aaagctcaagaaattcaaaagacaatgtgggatgagctggatctctggcactccaagcta aatgagctggattctgaagttcaggacattgttgaacaggacccaggacaagctcaagaa tggatggataacttgatgattcctttccagcagtatcagcaagtatcacagagggcagaa tatagaacctcacagttaaacaaggccacaattaagctggaggagtatcatgatcttttg aagagtactgaggcttggatagaaaataccagtcgtttgctggccgatcctgcagactat gactcttcaaagacgctgagtcaccacgctagtacccttcagatggctttggaagatgca gaacagaagcacaatcttttgcattcaattttcatggatctagaaggcttgtcaataatt tttgaaacagatactttagcacagcctatacaagacttaagtcatcacatagtagcttta cgacaaaaaatcatagaaagccttccccagattcaacgaatggctgatgatgtggttgcc attgaaacggaagtaaaatcaatggagaaaagagtttcaaaaatcaaagctatcctgcta tcaaaagaaatatttgatttttcacctgaagagcatcttaagcatggggaggtcatactg gaaaatatacatcccatgaagaaaaccattgctgaaatcgtgtcttaccaagtggaactg aggttaccccagacaggaatgaagcctctgcctgtgtttcagcggacagatgagctttta caagatataaaactgttggaaaatgtgactcaggaacaaaatgagttattaaagatagtc ataaaacagacaaatgaatgcgatgaagaaatagaaaaattgaaacagatcttaaataat tattcagctgaattctcccatgaacatatgtcaccagaccgagctgccaacctgccacaa gtacagggagaaatcgaaggtacggaaaagcagattctgagcttgaaccagagaaaagaa gacctgttggtggacttgaaggctgccgtactaaaacttcaccagcattttcagcaaaaa cagcaagaattagaagaggaaatgctgtcagccagagcatcagacgaggatggaggggct gagagggatgcttctgaatggaagttgaacagaacgggctccatgttcttcctgccagcc gtcgaggaagaggtggaagaaagctccctgaagagcgaaagtggagataagaaagcagag ccaccttccaggtccccatctttactctggaaacatgacaaggatgtggaggaagacagg acatcctcgtcctctggaacgatggttcaggaggcagcttggaaaataagcatgtgtgat agttccacggcacagatttttgcacaagactcactaaacactgagcaaggcccagaattt tccctgagccccaaccaaacacaagagggtaccacacctcctatcaaggttgcagctctg ggcttttctgatgagcaaggagcttttgaggccacagtggagaaagcaaggcccaagcct gcggaagtcctccatgtctgcaagaaccaggtggctgagctggagctgtggctgcagcaa gccaacgtggcattcgagccagaaacgttagatgcagacatgcagcaggtggtggaacag cagctggtagggtgccaggctatgctaacagagattgagcacaaggttgcctctctgtta gagaattgcaaagatcagggcctgggagacagtggagccactcaacaggaggctgaagca ctttccttgaaactaaaaactgtgaagtgcaatttggaaaaagtccagatgatgctgcag gagaaatacagcgagaaccagcattctaccatgctaaagaaatcttccgagcatcagaaa gttctccaaccagataacctttctgaatttgaatctgttgtaactgaaaggccacagttt agcagacaaaaagatttccagcagcaacaggttctggagttaaaaccaatggaacagaaa gatttaatcaaattcatagaatttaatgctaacaaaatatggcctcagtatcgccaacat gataaagatacaactcagccatcatctgtgagcagtaaggcatctagccctgaaaatgat gctccagacttgatcttgtcaacccagggccaaagtggagataaatggcaatatttacat catgaactttcatcaaaaattcggctccctctacctcagcctgtgcagccccaggttgcc acaaatatgagtgttctacccagtgtgagtatatataactttagatacccaacaactgaa gaactgaaaacttataccacccaacttgaagacctccgtcaagaagcaaataatcttcag acacaggaagacgtgtcagaagaagcatatgcaaatttggataagaaattacttgaactc tttctgaccctcagtcagtgcctgggcagtgtggaggagatgctgcagaccccttggctc ctgagaggggatgtcggtgcccagcaggtgcactacgagactctggctcttgagttgaaa aagctttgcttagctatgagtgacaagaagaatgatatttcaaaagccatgacttggcct ggcaagaacgccagcctgttccttgactgttttgataacctccaaatctacctggagcac atccaggctacaactgcctctaggagcaagtccctgaaagctggcctcgactataaccgc agttatcagaatgaaataaagcgattatatgatcaacttattaagaataaaacatcttta caacaatctctgaatgaaattagtggccagagtattgatgaacagcttcagaaagcagat gcatatacagtggagctgcagaactctgagagccgagtggcaaaactaagagacgaaggg gagaggcttcatttaccttctgttctactccaggaggtttacaaattagaggatgtactt gacagaatgtggggaatcctgagagccaggtacacaaaactcagcagccctttcatcact gagagccagcaagatgctttgttgcaaggcatggtagaactggtgaatatcggaaaggaa aatcttgctcatgaccacttacaacaaaccaaaagtaaagttgccttacaggctcaaata caaaatcacaagctttttttccggaagcttgttgctgacatgctgttgatccaaacatac tccaacaaaatgcttccttctttattgcaaaagaaagagacagtttgggcagaacaagta aaggaagttaaattactagaagaaaagtcacaccagtgtggaataaagctgcaaagttta ttgcagaaatgggaagaatttgatgaaaactatgcgtctcttgaaaaggacctggaaatt cttgtatctacattgccctctgtgagtttggtggaagagacggaggaaagattaatggaa aggatttcattttatcagcaaataaaaaggaacatcgatgagaagcatgcccggctttac cagactgtgaatgaaggcaaacagctggtggtttccgtgagctgtcctgaactagagggc cagattgcaaaactggaagagcagtggttgtccctaaacaaaaaaattgatcatgaacta catagactgcaaacgcttctcaagcatctgctcagttataacagagattcagatcagtta accaagtggttggaatcttctcagcaaactctgaactactggaaagagcagtccctcaat gtgtctcaggacttggacacaatcagaagcaacataaacaatttttttgagttttcaaag gaacttgatgaaaagtcctccttgaaaactgcagttctaagtactgggaaccaacttctt cacctgaaagaagctgatacagcgacactgagagcttctttagcacagtttgaacaaaag tggacaatgctcataactcaacttcctgacatccaagaaaaacttcaccagcttcagatg gagaaattgccatctcgtaaagcaataacagaaatgattaactggatgaacgatgtggag catcaaactgcagatgaagactctgagcattcactgagttctgcatctcaagttaaaaat cttcttcacaagtacaaggagtttagaatggaaatggactataaacaatggatagttgac tttgttaaccagtcattacttcagttaagcacctgtgatgtggaaagtaagcgctatgag agaacagagtttgcagagcatctcggagagatgaaccgccaatggcaccgggtccatgga acactgaatggaaagatacaacaattagaacaacttttggaaagtatcactgagaatgaa aacaaaatacagattctgaacaactggatggaggcacaagaggagagactgaacacttta caaaaacctgaaagtgtgatctcggtgcagaagacgctcctggattgtcaggatatagaa aatcaacttgcaattaaatccaaagcattggatgaattgagacaaagttacctgacttca gagagtgggacaatgccattgctggaagatacagcatccagaattgatgagttatttcaa aagaaaaccagtgttatcaaccaggtcaatgagctcaagacctccatgcagtctgtttta caggagtggaagacttatgataaactctatgatgaagtgaatatgatgacgatccgattc tggtaccgcatggaacacagcaaacctgtggttttatcattagaggccttaaggtgccag gtgcagaaccttcagactcttcaagatgaagctgagagcagtgaagggagttggaagaaa ctccaggaggttattggaaaactcaaagattactgcccctcagttgctgaaataattcaa gagaaatgccaaaatactcacacaaggtggacgcaggtaaaccaagacattgcagaccag ttgcagagggcccagagcccgctacagctctggaaggcatataacagtgctcacgctgaa gctgcagcaagactggagcagcaggaagcaaagtaccaacagctcgcaaacatcaacaca tctggaaacaacctggcagagatcctgcccccagccctgcaggacgtaaaggagttgcag catgatgtgcagaagacaaaagaagcctttctccaagattccactctcctggatcgactc ccacagcctgcagagcccaacacgcacgtgctcctctctggtcaaatgcactccctccag agggcttcctacttggaaaagatgctgcttatgaaaacaaatgaatttaagtttgttcta tcacagttcaaggattttggggaccagttggactctttaaaaggtctcattacgcatgaa gaagagaatttggataaactctaccagcaagaaaaagaaggaaatcctgacttattcctg aatcatgtgctggcactgacagcccagtcacctgatattgagcatttgaatgaagtaagc ctcaagctcccacttagtgacgtagctgtcaagacattacaaaatgtgaaccggcaatgg attcgggccacggcgacagcactggaacgctgcagtgaacttcaggggattggattgaat caaaagtttctttattgctgtgaaaagtgggtccagcttttggagaagatagaagagatg ctcaaggtgaacattgctgacagcctccctgctctcctggaacagcagaaaacgtatgag atgttagaagctgaagtttctataaaccagacaattgctgactcttatgtcacccagtgc ttacagctcctggacacagcagaaatagagaagagaccggaatttgtttggaagttcacg aggctgaaggagaggtggcagagtgctgcccagggcgttcggcagaggaagagtgacatc gatgagctggtgaggcagtggcagtacttcaccacctccgagggggacttgctccacctg ctcgcctacaccagccacctgctgtctgcagtgaagagccaggactgctacagcctccac caaacaagaagtctgatccatgagctgaagaataaagaaattcatttccagaggtggcag acaacctatgcactaaccttggaagctgggggcaagttactgagcacaactcacctggaa actaaagagtcaattgagaagagaatcagtcaacttcaggacacctggaaggacacaaaa ctccaactaggagagatgattaaacagttccagagcactgcagagacctgggaccagtgt gagaagaaaatcaaggagttgagaaacaggctgcaagttttaaaggcacagagtaaagat cctcttccagaacttcatgaggagctccatcgagaaaaagagctgattaaggaactagag aagtctttggctaactggactcagaacttgaaagaacttcacactatgaagaccgaccta acccagcacattcttgtggaggacgtggtggttttgaaagagcaaatagagcatttgcac agacaatgggaggacctctgcttaagagtggctatacgcaaacaggagatagaagacaga ctcaattcatggattgtgttcaatgaaaaaaataaagagttgtgtgcatggctggtgcag atggaaaacaaagttctccagacagcagatattagtattgaagaaatgattgaaaagctt cagaaggactgcatggaagaaataaatctgtttagtgaaaacaagttacagttaaaacaa atgggcgaccggttgatcaaggccagcaacaagacaagagcagctgagatcgatgacaag ctcaacaaaattaatgaccgttggcaacatctttttgatgtcattggatcaagggtgaag aagctgaaggagaccttcgcttttattcagcagttagacaaaaacatgagcaaccttcgc acctggttggctcggatcgagtctgagctctctaagcctgtggtttatgatgtctgtgat gatcaagagatccagaagaggctcgctgaacagcaggacctgcagcgagacatagaacag cacagtgcaggggtggagtctgtgtttaacatctgcgacgtcctcctgcacgactccgat gcctgtgccaacgagactgagtgcgactccgtccagcagaccaccaggagcctggaccgg cgctggaggaacatttgtgccatgtccatggagcggcggatgaaaattgaggagacatgg cggctttggcagaagtttttagatgattactcccgcttcgaggactggctcaagtccgcc gagaggacagcggcctgcccgaattcctccgaggtgctgtacaccgttgccaaagaagag ctgaagaggttcgaggccttccagcggcagatccacgagaggctcacgcagctggagctc atcaacaagcagtaccggcggctggcccgcgagaaccgcaccgacacggccagcaaactg aagcagatggtgcacgagggcaaccagcgctgggacaacctccagaagcgggtcacagcc atcctgcggagactccgacatttcaccaaccaaagggaagaattcgaggggaccagggag agcattctggtgtggctcacggagatggacctgcagctgaccaacgtggagcacttctcg gagagcgatgctgacgacaagatgcgccagctgaacggtttccagcaggaaattacatta aataccaacaagattgatcagcttatcgtttttggggagcagctcattcagaagagtgag cccctggatgccgtgctgattgaggatgagttggaggagctgcaccgctattgccaggaa gtgtttggcagggtctcccgattccaccggaggctcacctcccacgcgtcgggcttggaa gatgaaaaggaagcctctgagaatgaaacggatgtggaagaccccagagagatccaggac gactcttggcgtaaaaggagagagagcgaggagccctcgtcccctcagtccctttgtcac ctggtgcccccagcgccagggcccgagcgctccggctgtgagacccctgtcagcgtggat tccatcccgctggagtgggatcacacaggtgacgtggggggctcctcctctcacgaagaa gacgaggagggcccgtactacagcgcgctgtcagatgtagaaatccctgaaaatcctgag gcatatcttaaaatgaccacaaaaactttgaaagcgtcttctggtaaatccatttctgaa ggccactcgtggcatgttcctgacagccctccctgccgcaagcgtcgctacaaacaaatg ggaggtgacaggaatgtccaacccatcccctccgattccagcaccccttataaaccagcc tacgtaaagctgctgttgtctccagggactgaaggtggcaaagaagatcccagagtcctg actggcggcccacagcgggaagacgagggcctggctgctctcaccgggcagcagtcaggt gcctttgatagatgggagttgatccaagcgcaagaacttcacagtaaactcagaataaaa caaaacttgcagcagctgaactctgatatcagcgacatcaccacgtggctggaaaaaact gaagcagagctggaaacattaaagctggcaaagcctccctctggtatgcaggaaatggaa ctccgagtgaagaggctgaaggagatactaaaagcctttgacacctacaaggccttagtg gtttctgtcaacgtgagcagcaaggaatttctgcaaactgagagcaccgactccgaagag ctccaagatagagtcggccagctgcggctgcgctgggacgcggcccagggtgcggtggag agctggagagagggcttacggctgtcgctcatgcagtgccaggactttcaccagctgagt caaagcctgctgctgtggttagcgagcgccgagagccggaggcaggaggctcgtgtcact gaccaagaggcagacccccggcccctcctggcatgtcgggaggagctcctgcaactggaa aaggagctagtggagcgtcaacctcaagtgaactccttacaagagatttccagcagcctg cttatcaaggggcacagagaagactacattgaggctgaagagaaagtccatgttattgag aagaaactcaaacagttgcttgagcaagtgtcccaagacctagtgtccttgcagcaaagc cagaacccagactcacctctgcccagcttggatgaagcagaccccagagagcctctagca gcacctgtaccagctccccaagccaagcagttcagagcagaggtaactacaaaagacaag accaagacagccagcagggtgcccagccccgctggccctgaaagctcgcggccccagcgc tccttcctctggcgggtgatcagggcggcgctgcccctccagctgcttctgctgctgctg ctgctcctggcctgcctgctgccctcctccgaagaggactacagctgcactcaggccaac aactttgccaggtccttttaccccatgctgaggtacaccaatgggccaccccccacctag

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