Delphinapterus leucas (beluga whale): 111173087
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Entry
111173087 CDS
T05885
Symbol
HIF1A
Name
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle04066
HIF-1 signaling pathway
dle04137
Mitophagy - animal
dle04140
Autophagy - animal
dle04148
Efferocytosis
dle04659
Th17 cell differentiation
dle04919
Thyroid hormone signaling pathway
dle05167
Kaposi sarcoma-associated herpesvirus infection
dle05200
Pathways in cancer
dle05205
Proteoglycans in cancer
dle05208
Chemical carcinogenesis - reactive oxygen species
dle05211
Renal cell carcinoma
dle05230
Central carbon metabolism in cancer
dle05231
Choline metabolism in cancer
dle05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
111173087 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
111173087 (HIF1A)
04137 Mitophagy - animal
111173087 (HIF1A)
04148 Efferocytosis
111173087 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
111173087 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
111173087 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111173087 (HIF1A)
05205 Proteoglycans in cancer
111173087 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
111173087 (HIF1A)
05230 Central carbon metabolism in cancer
111173087 (HIF1A)
05231 Choline metabolism in cancer
111173087 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
111173087 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
111173087 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
111173087 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
dle03000
]
111173087 (HIF1A)
Transcription factors [BR:
dle03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
111173087 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
DDRGK
Motif
Other DBs
NCBI-GeneID:
111173087
NCBI-ProteinID:
XP_022426136
UniProt:
A0A2Y9MZ41
LinkDB
All DBs
Position
Unknown
AA seq
823 aa
AA seq
DB search
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET
DEQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPASETPKPLRSSADPALNQEVALKLEP
NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF
AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTTPQSASTITVFQ
PTQMQEPPITTNTTTATTDELKTVTKDGMEDIKILIAFPSPPHVPKETTCATTSPYSDTG
SRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELSPKILALQNAQRKRKIE
HDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLL
GQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2472 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagag
aagtctagagatgcagccagatctcgacgaagtaaagagtctgaagttttttatgagctt
gctcatcagttgccacttccccataatgtgagctcacatcttgataaggcttctgttatg
aggcttaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttggatatt
gaagatgaaatgaaggcacagatgaattgcttttatttgaaagccttggacggttttgtt
atggttctcacagatgatggtgacatgatttacatttcggataatgtgaacaaatacatg
gggttaactcagtttgaactaaccggacacagtgtgtttgattttactcatccgtgtgac
catgaggaaatgagagaaatgcttacacacagaaatggccttgtgaaaaagggtaaagag
caaaatacacagcggagcttttttctcagaatgaagtgtaccctaactagccggggaaga
actatgaacataaagtctgcaacatggaaagtacttcactgcacaggccatattcatgta
tatgataccaatagtaaccaatctcaatgtgggtataagaaaccacctatgacatgcttg
gtgctgatttgtgaacccattcctcatccgtcaaatattgaaattcctttagacagcaag
acttttctcagtcgtcacagtctggatatgaagttttcttattgtgatgaaagaattaca
gaattgatgggatatgagccagaagaacttttgggccgctcaatttatgaatattatcat
gctttggactctgatcatctgaccaaaactcatcatgatatgtttactaaaggacaagtc
accacaggacagtacaggatgcttgccaaaagaggtggctatgtctgggttgaaactcaa
gcaactgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaattat
gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc
ctcaaaccagttgaatcttcagacatgaaaatgactcagctattcaccaaagttgaatca
gaagatacaagtagtctctttgataaacttaagaaggaacctgatgctttaactttgctg
gccccagctgctggagacacaatcatatctttagattttggcagcaatgacacagaaact
gatgaacaacaacttgaggaagttccattgtataatgatgtaatgctcccctcatccaat
gagaaattacagaatataaatttggcaatgtctccattacctgcctctgaaactccaaag
ccacttagaagtagtgctgaccctgcactcaatcaggaagttgcattaaagttagaacca
aatccagagtcactggaactttctttcaccatgccccagattcaagatcagccagctagt
ccttctgatggaagcaccagacaaagttcacctgagcctaacagtcccagtgaatattgt
tttgatgtggatagtgatatggtcaatgaattcaagttggaattggtagagaaacttttt
gctgaagacacggaagcaaagaatccattttccactcaggacactgatttagacttggag
atgttagctccttatatcccaatggatgatgacttccagttacgttccttcgaccagttg
tcaccattggaaagcagttctactactcctcaaagtgcgagcacaattacagtattccag
ccgactcaaatgcaggaacctcctataaccaccaacactaccacagccaccactgatgaa
ttaaaaacagtgacaaaagatggtatggaagacattaaaatattgattgcatttccatct
cctccccacgtacctaaagaaactacttgtgccacaacatcaccatatagtgacactgga
agtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacagacagaaaaatct
catccaagaagccctaatgtgttatctgtcgctttgagtcaaagaactactgttcctgag
gaagaactaagtccaaagatactagctttgcagaatgctcagagaaagcgaaaaatagaa
catgatggctcactttttcaagcagtgggaattggaacattattacagcaaccagatgat
cgtgcaactactacatcactttcttggaaacgcgtaaaaggatgcaaatctagtgaacag
aatggaatggagcaaaagacaattattttaataccctctgatttagcatgtagactgctg
gggcaatcaatggatgagagtggattaccacagctgaccagttatgattgtgaagttaat
gctcctatacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggat
caagttaactga
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