Delphinapterus leucas (beluga whale): 111173177
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Entry
111173177 CDS
T05885
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle01521
EGFR tyrosine kinase inhibitor resistance
dle01522
Endocrine resistance
dle04010
MAPK signaling pathway
dle04012
ErbB signaling pathway
dle04014
Ras signaling pathway
dle04062
Chemokine signaling pathway
dle04068
FoxO signaling pathway
dle04072
Phospholipase D signaling pathway
dle04150
mTOR signaling pathway
dle04151
PI3K-Akt signaling pathway
dle04510
Focal adhesion
dle04540
Gap junction
dle04630
JAK-STAT signaling pathway
dle04650
Natural killer cell mediated cytotoxicity
dle04660
T cell receptor signaling pathway
dle04662
B cell receptor signaling pathway
dle04664
Fc epsilon RI signaling pathway
dle04714
Thermogenesis
dle04722
Neurotrophin signaling pathway
dle04810
Regulation of actin cytoskeleton
dle04910
Insulin signaling pathway
dle04912
GnRH signaling pathway
dle04915
Estrogen signaling pathway
dle04917
Prolactin signaling pathway
dle04926
Relaxin signaling pathway
dle04935
Growth hormone synthesis, secretion and action
dle05034
Alcoholism
dle05160
Hepatitis C
dle05161
Hepatitis B
dle05163
Human cytomegalovirus infection
dle05165
Human papillomavirus infection
dle05200
Pathways in cancer
dle05205
Proteoglycans in cancer
dle05206
MicroRNAs in cancer
dle05207
Chemical carcinogenesis - receptor activation
dle05208
Chemical carcinogenesis - reactive oxygen species
dle05210
Colorectal cancer
dle05211
Renal cell carcinoma
dle05213
Endometrial cancer
dle05214
Glioma
dle05215
Prostate cancer
dle05220
Chronic myeloid leukemia
dle05221
Acute myeloid leukemia
dle05223
Non-small cell lung cancer
dle05224
Breast cancer
dle05225
Hepatocellular carcinoma
dle05226
Gastric cancer
dle05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111173177 (SOS2)
04012 ErbB signaling pathway
111173177 (SOS2)
04014 Ras signaling pathway
111173177 (SOS2)
04630 JAK-STAT signaling pathway
111173177 (SOS2)
04068 FoxO signaling pathway
111173177 (SOS2)
04072 Phospholipase D signaling pathway
111173177 (SOS2)
04151 PI3K-Akt signaling pathway
111173177 (SOS2)
04150 mTOR signaling pathway
111173177 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
111173177 (SOS2)
04540 Gap junction
111173177 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
111173177 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
111173177 (SOS2)
04660 T cell receptor signaling pathway
111173177 (SOS2)
04662 B cell receptor signaling pathway
111173177 (SOS2)
04664 Fc epsilon RI signaling pathway
111173177 (SOS2)
04062 Chemokine signaling pathway
111173177 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
111173177 (SOS2)
04912 GnRH signaling pathway
111173177 (SOS2)
04915 Estrogen signaling pathway
111173177 (SOS2)
04917 Prolactin signaling pathway
111173177 (SOS2)
04926 Relaxin signaling pathway
111173177 (SOS2)
04935 Growth hormone synthesis, secretion and action
111173177 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
111173177 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
111173177 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111173177 (SOS2)
05206 MicroRNAs in cancer
111173177 (SOS2)
05205 Proteoglycans in cancer
111173177 (SOS2)
05207 Chemical carcinogenesis - receptor activation
111173177 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
111173177 (SOS2)
05231 Choline metabolism in cancer
111173177 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
111173177 (SOS2)
05225 Hepatocellular carcinoma
111173177 (SOS2)
05226 Gastric cancer
111173177 (SOS2)
05214 Glioma
111173177 (SOS2)
05221 Acute myeloid leukemia
111173177 (SOS2)
05220 Chronic myeloid leukemia
111173177 (SOS2)
05211 Renal cell carcinoma
111173177 (SOS2)
05215 Prostate cancer
111173177 (SOS2)
05213 Endometrial cancer
111173177 (SOS2)
05224 Breast cancer
111173177 (SOS2)
05223 Non-small cell lung cancer
111173177 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
111173177 (SOS2)
05160 Hepatitis C
111173177 (SOS2)
05163 Human cytomegalovirus infection
111173177 (SOS2)
05165 Human papillomavirus infection
111173177 (SOS2)
09165 Substance dependence
05034 Alcoholism
111173177 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111173177 (SOS2)
01522 Endocrine resistance
111173177 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
PH_19
IQ_SEC7_PH
PH_10
PH_13
Motif
Other DBs
NCBI-GeneID:
111173177
NCBI-ProteinID:
XP_022426331
UniProt:
A0A2Y9MZN4
LinkDB
All DBs
Position
Unknown
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRDLFKPSDI
EKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEHEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
EAVELSQDHFKKYLLKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGTMKSDDDPPAIPPRQPPPPKVKPRVPAPSGAFDGPL
HSPPPPPPRGPLPDTPPPVPLRPPEHFINCPFTLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCYVLSSSQNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSQPPLY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaacgaaga
aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactaccatgtgtccctatatattgtggctgtactagagtatatctcagctgat
attttgaaattggctggtaattatgtttttaatatccgacattatgaaatatcccaacag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggcttggtttctctttgtgaagatgaacctagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaagacagtatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcttttctttctgacagagacctgtttaaaccttctgatatt
gaaaagattttcagtaacattttagatatacatgaattgaccgtgaaacttttaggttta
attgaagacacagttgaaatgactgatgaaagcagccctcatcccttagctggaagctgt
tttgaagatttggcagaggaacaagcatttgatccttatgaaacattatcacaggatatt
ctttcaccaaaatttaatgaacatttcagtaagttgatggccagacctgcagtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctggtgccagtatatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcatgaagacagagaatgtttgaaccaagctattactgctcttatgaat
ctccaaggtagcatggaccgaatttacaagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcacctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaatttattatggaaggcccattgacaagaattggtgctaaacacgaacggcatattttt
ctctttgatggcttaatgattagctgcaaacccaatcatagccagtcacgccttccagga
tacagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaaatacaaatatgt
gataaagaagatacttgtgagtgcaagcatgcttttgaattagtatccaaagatgaaaac
agcataatatttgctgctaagtctgctgaagagaaaaataattggatggcagcacttatt
tctcttcattatcgtagtactctagatcgaatgctagattcagtattactgaaggaagaa
aatgaacaaccacttagattaccgagtcctgaagtgtatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa
ggaggaactgtggtgaaattaattgaaaggttaacatatcacatgtatgcagatcccaat
tttgttcgcacttttcttactacgtatcgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggca
gtagagaaaggcgagcagccaatcagtgcagaccttaaaaggtttcgcaaggaatacgtc
caaccagtacaacttaggatcttgaatgtgtttcggcactgggttgaacaccatttttat
gactttgaaagagacttggagttgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccaccaattgaa
tggcatatcagcagaccaggacagtttgaaacgtttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagttcaaccttct
gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccacaccacaaatctcactctctggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgggtggcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattagagatcgtcagtgcagtaaattcagtatca
gtctatagactagatcatacctttgaggcattgcaggaaagaaaaaggaaaattttggat
gaagctgtggaattaagtcaagatcattttaaaaaatatctgttgaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcaatatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggaggttctttgaaaaccttaaccccatgggaaatgcttctgaa
aaagagtttacagattatctgttcaacaagtcactagaaattgaaccccggaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggtactttacgaggtcatccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaacagagcttgaatcaacagtg
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggaagcaatagcatctttgctcca
gtcctcttgcctcattcaaagtctttctttagttcgtgtggtagtttacataaactaagt
gaagagccactgattcctcctccacttcctcctcgaaaaaaatttgatcatgatgcttca
aattccaagggaactatgaaatctgatgatgacccccctgctattccaccaagacagcct
cctcctccaaaggtaaaacccagagttcctgctccttctggtgcatttgacgggcctctg
catagtccaccgccgccgccgccgagaggtcctcttcccgatacccctccaccagttccc
cttcggcctccagaacactttataaactgtccgtttactcttcagccacctccactggga
catcttcacagagatccagactggttcagagacgttagtacgtgtccaaattctccaaac
actcctcctagcacaccctctccaagggtaccacgtcgatgctacgtgctcagttctagt
cagaataatcttgctcatcctcaagctccccctgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttacaaacgggagctttcgcaacccccattgtat
agactgcctttgctagaaaatgcagaaactcctcaatga
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integrated database retrieval system
