Delphinapterus leucas (beluga whale): 111174855
Help
Entry
111174855 CDS
T05885
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle01521
EGFR tyrosine kinase inhibitor resistance
dle01522
Endocrine resistance
dle04010
MAPK signaling pathway
dle04012
ErbB signaling pathway
dle04014
Ras signaling pathway
dle04062
Chemokine signaling pathway
dle04068
FoxO signaling pathway
dle04072
Phospholipase D signaling pathway
dle04150
mTOR signaling pathway
dle04151
PI3K-Akt signaling pathway
dle04510
Focal adhesion
dle04540
Gap junction
dle04630
JAK-STAT signaling pathway
dle04650
Natural killer cell mediated cytotoxicity
dle04660
T cell receptor signaling pathway
dle04662
B cell receptor signaling pathway
dle04664
Fc epsilon RI signaling pathway
dle04714
Thermogenesis
dle04722
Neurotrophin signaling pathway
dle04810
Regulation of actin cytoskeleton
dle04910
Insulin signaling pathway
dle04912
GnRH signaling pathway
dle04915
Estrogen signaling pathway
dle04917
Prolactin signaling pathway
dle04926
Relaxin signaling pathway
dle04935
Growth hormone synthesis, secretion and action
dle05034
Alcoholism
dle05160
Hepatitis C
dle05161
Hepatitis B
dle05163
Human cytomegalovirus infection
dle05165
Human papillomavirus infection
dle05200
Pathways in cancer
dle05205
Proteoglycans in cancer
dle05206
MicroRNAs in cancer
dle05207
Chemical carcinogenesis - receptor activation
dle05208
Chemical carcinogenesis - reactive oxygen species
dle05210
Colorectal cancer
dle05211
Renal cell carcinoma
dle05213
Endometrial cancer
dle05214
Glioma
dle05215
Prostate cancer
dle05220
Chronic myeloid leukemia
dle05221
Acute myeloid leukemia
dle05223
Non-small cell lung cancer
dle05224
Breast cancer
dle05225
Hepatocellular carcinoma
dle05226
Gastric cancer
dle05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111174855 (SOS1)
04012 ErbB signaling pathway
111174855 (SOS1)
04014 Ras signaling pathway
111174855 (SOS1)
04630 JAK-STAT signaling pathway
111174855 (SOS1)
04068 FoxO signaling pathway
111174855 (SOS1)
04072 Phospholipase D signaling pathway
111174855 (SOS1)
04151 PI3K-Akt signaling pathway
111174855 (SOS1)
04150 mTOR signaling pathway
111174855 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
111174855 (SOS1)
04540 Gap junction
111174855 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
111174855 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
111174855 (SOS1)
04660 T cell receptor signaling pathway
111174855 (SOS1)
04662 B cell receptor signaling pathway
111174855 (SOS1)
04664 Fc epsilon RI signaling pathway
111174855 (SOS1)
04062 Chemokine signaling pathway
111174855 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
111174855 (SOS1)
04912 GnRH signaling pathway
111174855 (SOS1)
04915 Estrogen signaling pathway
111174855 (SOS1)
04917 Prolactin signaling pathway
111174855 (SOS1)
04926 Relaxin signaling pathway
111174855 (SOS1)
04935 Growth hormone synthesis, secretion and action
111174855 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
111174855 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
111174855 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111174855 (SOS1)
05206 MicroRNAs in cancer
111174855 (SOS1)
05205 Proteoglycans in cancer
111174855 (SOS1)
05207 Chemical carcinogenesis - receptor activation
111174855 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
111174855 (SOS1)
05231 Choline metabolism in cancer
111174855 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
111174855 (SOS1)
05225 Hepatocellular carcinoma
111174855 (SOS1)
05226 Gastric cancer
111174855 (SOS1)
05214 Glioma
111174855 (SOS1)
05221 Acute myeloid leukemia
111174855 (SOS1)
05220 Chronic myeloid leukemia
111174855 (SOS1)
05211 Renal cell carcinoma
111174855 (SOS1)
05215 Prostate cancer
111174855 (SOS1)
05213 Endometrial cancer
111174855 (SOS1)
05224 Breast cancer
111174855 (SOS1)
05223 Non-small cell lung cancer
111174855 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
111174855 (SOS1)
05160 Hepatitis C
111174855 (SOS1)
05163 Human cytomegalovirus infection
111174855 (SOS1)
05165 Human papillomavirus infection
111174855 (SOS1)
09165 Substance dependence
05034 Alcoholism
111174855 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111174855 (SOS1)
01522 Endocrine resistance
111174855 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_19
PH_10
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
111174855
NCBI-ProteinID:
XP_022429725
UniProt:
A0A2Y9N647
LinkDB
All DBs
Position
Unknown
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENVQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISL
TKSTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSVSD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHSNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcatcctactcttgagtct
agtgatgatgctcttcagtatgttgaagaattaattttgcagttattaaatatgctatgc
caagctcagccgcgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccagtcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttgttaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagac
attttaaagctggtggggaattatgtgcgaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacaatacataagggaacttaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtggatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtagaaatgacagatgaaggcagtccccatccattagtagga
agttgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacgacctggttttcatgatcgtttccttagtcagttatcaaagcctggagcg
gcactctatttgcagtcaataggcgaaggtttcaaagaagctgttcaatatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttctgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgctctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagagtatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaagatgacaccaatgagtacaagcatgcttttgagataattttaaaagat
gaaaatagcgtcatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacagtaccggagtacactggaaaggatgcttgatgtgacaatgctacag
gaagaaaaggaggagcagatgaggctccctagtgctgatgtttatagatttgcagagcct
gactctgaagaaaatatcatatttgaagaaaacgtgcagcccaaagctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggctcacataccatatgtacgcagat
cccaattttgttcggacatttcttacaacatatagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccttgagtgcagaactaaaaaggtttagaaaagaa
tatatacagcctgtacaactgcgagtattaaatgtatgtcggcactgggtagagcaccac
ttctacgattttgaaagagatgcagatcttttgcagcgaatggaggaatttattggaaca
gtaagaggtaaagcaatgaaaaagtgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcaccccctaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacagctcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaggaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcataccactaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattctgcaa
gtctttcaagagctgaacaacttcaatggtgtccttgaggttgtcagtgctatgaactca
tcacctgtatacagactagaccacacgtttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaactaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaaggcatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggcgagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccaatgggaaatagt
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtactatgagacatcccacacctctgcagcaagagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttctagtaccacagat
gtttgcagcgtatttgattctgatcattcaagcccttttcactcaagcagcgataccgtc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaagagcactgatgaagtgcctgtcccccctcctgttcctccacgaagacgaccagaa
tctgccccagcggaatcttcgccatctaagatcatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcctattcaccacgatattcagtatcagac
cggacctctatatcagatcctcctgaaagccctcccttattacctccacgagaacccgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatagtaatgccttcttcccaaacagcccttccccctttacaccacctcct
cctcaaacaccttctcctcacggcacaagaaggcatctgccatcaccaccattgacacaa
gaagtggaccttcattccattgctgggccgcctgttcctccacgacaaagcacttctcaa
catatccctaaactccctccaaaaacttacaaaagggagcatacacacccatccatgcac
agagatggaccaccactgttggagaatgctcattcttcctga
DBGET
integrated database retrieval system
