Delphinapterus leucas (beluga whale): 111176849
Help
Entry
111176849 CDS
T05885
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle00220
Arginine biosynthesis
dle00330
Arginine and proline metabolism
dle01100
Metabolic pathways
dle04020
Calcium signaling pathway
dle04022
cGMP-PKG signaling pathway
dle04066
HIF-1 signaling pathway
dle04071
Sphingolipid signaling pathway
dle04151
PI3K-Akt signaling pathway
dle04370
VEGF signaling pathway
dle04371
Apelin signaling pathway
dle04611
Platelet activation
dle04915
Estrogen signaling pathway
dle04921
Oxytocin signaling pathway
dle04926
Relaxin signaling pathway
dle04931
Insulin resistance
dle04933
AGE-RAGE signaling pathway in diabetic complications
dle05415
Diabetic cardiomyopathy
dle05417
Lipid and atherosclerosis
dle05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
111176849 (NOS3)
00330 Arginine and proline metabolism
111176849 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
111176849 (NOS3)
04371 Apelin signaling pathway
111176849 (NOS3)
04066 HIF-1 signaling pathway
111176849 (NOS3)
04020 Calcium signaling pathway
111176849 (NOS3)
04071 Sphingolipid signaling pathway
111176849 (NOS3)
04022 cGMP-PKG signaling pathway
111176849 (NOS3)
04151 PI3K-Akt signaling pathway
111176849 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
111176849 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
111176849 (NOS3)
04921 Oxytocin signaling pathway
111176849 (NOS3)
04926 Relaxin signaling pathway
111176849 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
111176849 (NOS3)
05418 Fluid shear stress and atherosclerosis
111176849 (NOS3)
05415 Diabetic cardiomyopathy
111176849 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
111176849 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
111176849 (NOS3)
Enzymes [BR:
dle01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
111176849 (NOS3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
DEC-1_N
Motif
Other DBs
NCBI-GeneID:
111176849
NCBI-ProteinID:
XP_022433504
UniProt:
A0A2Y9NEZ8
LinkDB
All DBs
Position
Unknown
AA seq
1205 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCSKQGPASPAPEPSRAPAPAPPPAPDHSPAPNSPQ
LTRPPEGPKFPRVKNWEAGSITYDTLCAQSQQDGPCTPRRCLGSLVFPRKLQSRPSQGPP
PPEQLLSQARGFINQYYSSIKRSGSQAHKERLQEVEAEVAATGTYQLRESELVFGAKQAW
RNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAVTVFPQRAPGR
GDFRIWNSQLVRYAGYRQQDGSVRGDPANVEVTELCIQHGWTPGNGRFDVLPLLLQTPDE
APELFVLPSELVLEVPLEHPTLEWFSALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYM
STEIGMRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIV
DHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPD
PWKGSTAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYASETGRAQSYAQQL
GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYN
SSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYP
HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAQA
AAQDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATVLLVENLQSSKSTRAT
ILVRLDTGSQEGLQYQPGDHIGICPPNRPGLVEALMSRVEDPPPPTEPVAVEQLEKGSPG
GPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPSEQQELETLSQDPR
RYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVA
VLAYRTQDGLGPLHYGVCSTWLSQLKTGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGI
APFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYREEVQDAQQRGVFGRVLTAFS
REPNSPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDME
LDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHMRGAVPWAFDPPGP
DTPGP
NT seq
3618 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtgggccaggagcccgggccaccctgcggcctggggctaggg
ctgggcctcgggctgtgcagcaaacagggcccggcctccccagcacccgagcccagccgg
gcaccggcacccgcacccccgcccgcgccagaccacagcccggctcccaacagcccccag
ctaacccggcctccagaggggcccaagttccctcgcgtgaagaactgggaggcggggagc
atcacctacgacactctgtgtgcgcagtcacagcaggacgggccctgcacccccagacgc
tgcctgggctccctggtgtttccacggaaactgcagagccgaccctcccagggccctccg
cccccggagcagctgctgagccaggccaggggcttcatcaaccagtactacagctccatc
aagaggagcggctcccaggctcacaaggagcggcttcaggaagtggaagccgaggtggcg
gccacgggcacctaccagcttcgtgagagcgagctggtgttcggggccaagcaggcctgg
cgcaacgccccccgctgcgtgggccggatccagtgggggaagctgcaggtgtttgatgcg
cgggattgcagctctgcacaggagatgttcacctacatctgcaaccacatcaagtacgcc
accaaccggggcaacctccgttcggccgtcacggtgttcccccagcgcgctccgggccgc
ggagacttccgcatctggaacagccagctggtacgctacgcgggctacaggcagcaggac
ggctccgtgaggggggacccggccaacgtggaggtcaccgagctctgcatccagcatggc
tggaccccaggaaacggccgctttgatgtgctacccctgctgctccagaccccagatgag
gctccagaactctttgttctgccctccgaactggtcctcgaggtccccctggagcacccc
acgctggagtggttctcggccctgggcctgcgctggtacgccctcccagcagtgtccaac
atgctgctggaaattgggggcctggagttccctgcagcccccttcagcggctggtacatg
agcacggagattggcatgcggaacctgtgtgatccccaccgctacaacatcctggaggac
gtggccgtctgcatggacctggatacccggaccacctcatccctgtggaaagacaaggca
gccgtggaaatcaacttggctgtgctgcacagttaccagctcgccaaagtgaccattgtg
gaccaccacgctgccacggcctccttcatgaagcacctggagaacgagcagaaggccagg
gggggctgccctgctgactgggcctggatcgtgcccccgatctcgggcagcctcacccca
gtcttccatcaggagatggtcaactatgtcctgtcccctgctttccgctaccagccagac
ccctggaaggggagcacagccaagggcaccggcatcaccaggaagaagacctttaaggaa
gtggccaatgcggtgaagatctctgcctcactcatgggcaccgtgatggcgaagcgagtg
aaggcgacgattctgtacgcctccgagaccggccgggcccagagctacgcacagcaactg
gggaggctcttccggaaggccttcgaccctcgggtcctgtgcatggatgagtatgacgtg
gtgtccctggagcacgagacgctggtgttggtggtgaccagcacctttgggaacggcgat
cccccagagaatggagagagttttgcagcagccctgatggagatgtcgggcccctacaac
agctcccctcggccagagcaacacaagagttacaaaatccgcttcaacagcgtctcctgc
tcagacccgctggtgtcctcctggcggcggaagaggaaggagtccagtaataccgacagc
gcgggggcgctggggaccctcaggttctgtgtgtttgggctgggctcccgggcgtacccc
catttctgcgcctttgctcgtgcggtggacacgcggctggaagagctgggaggggagcgg
ctgcttcagctgggccagggcgatgagctgtgtggccaggaggaggccttccgcggctgg
gcccaggctgccttccaggcctcctgtgagacgttctgcgtgggggaggatgcccaggcc
gcggcccaggacatcttcagccccaaacggagctggaaacgccagaggtaccggctgagc
gcccaggccgagggcctccagctgctgccaggcctgatccacgtgcacaggcggaagatg
ttccaggccacagtcctcttggtggaaaacctgcaaagcagcaagtccacccgggccacg
atcctggtgcgcctggacacgggaagccaggaggggctccagtaccagccgggggaccac
ataggcatctgcccgcccaaccggccggggctcgtggaggcactgatgagccgcgtggag
gacccgccgccgcccaccgagcctgtggcagtggagcagctggagaagggcagcccaggt
ggccctcctcccggctgggtgcgggacccccggctgcccccgtgtacgctgcgccaggct
ctcacctttttcctggacatcacctccccgcccagccctcaacttcttcgactgctcagc
accctggctgaagagcctagtgaacagcaagagctcgagaccctcagccaggacccccgg
cgctacgaggagtggaagtggttccgctgccccaccctgctggaggtgctcgagcagttt
ccatccgtggcactgcctgccccgctgcttctcacccagctgcccctgctccagccccgg
tactactcggtcagctcagcacccagcacccatccaggagagatccacctcacagtagct
gtgctggcatacaggacccaagatgggctgggtcccctgcactatggagtctgctccacg
tggctgagccaactcaagactggagaccccgtaccctgcttcatcaggggggctccctcc
ttccggctgcctcctgatcccagcttgccctgcatcctcgtgggcccgggcactggcatc
gcccccttccggggattttggcaggagcggctacacgacatcgagagcaaagggctgcag
cctgcccccatgaccttggtgttcggctgccggtgctcccagctcgaccatctctaccgc
gaggaggtgcaggatgcccagcagcgcggggtgtttggccgcgtcctcaccgccttctcc
cgggaacccaacagccctaagacctacgtgcaggacatcctgcggacggagctggctgct
gaggtgcaccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgatgtcacc
atggcaaccagcgtcctgcagacggtgcagcgcatcttggcgacagagggcgacatggag
ctggatgaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggac
attttcgggctcacgctgcgcacccaggaagtgacaagccgcatacgcacccagagcttt
tccttgcaggagcggcatatgcggggcgcagtgccctgggcgttcgacccgcccggccca
gacacccctggtccctga
DBGET
integrated database retrieval system
