Delphinapterus leucas (beluga whale): 111177023
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Entry
111177023 CDS
T05885
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1
KO
K02599
Notch 1
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle01522
Endocrine resistance
dle04330
Notch signaling pathway
dle04658
Th1 and Th2 cell differentiation
dle04919
Thyroid hormone signaling pathway
dle05020
Prion disease
dle05165
Human papillomavirus infection
dle05200
Pathways in cancer
dle05206
MicroRNAs in cancer
dle05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
111177023 (NOTCH1)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
111177023 (NOTCH1)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
111177023 (NOTCH1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111177023 (NOTCH1)
05206 MicroRNAs in cancer
111177023 (NOTCH1)
09162 Cancer: specific types
05224 Breast cancer
111177023 (NOTCH1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
111177023 (NOTCH1)
09164 Neurodegenerative disease
05020 Prion disease
111177023 (NOTCH1)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
111177023 (NOTCH1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_CA
EGF_2
Ank_2
Ank
Notch
NOD
NODP
Ank_4
Ank_3
Ank_5
EGF_3
DL-JAG_EGF-like
Motif
Other DBs
NCBI-GeneID:
111177023
NCBI-ProteinID:
XP_022433868
UniProt:
A0A2Y9NWE7
LinkDB
All DBs
Position
Unknown
AA seq
2521 aa
AA seq
DB search
MPPLLAPLLCLALLPALAARGLRCSQPSETCLNGGKCEVFPNGTEACVCSGAFAGQRCQA
PNPCLSAPCKNGGTCHTVERDGLVDYTCRCRLGLSGPLCLTPRDHACLASPCLNGGTCDL
LTLTEYKCLCPPGWSGKTCQQADPCASNPCANGGQCLPFEASYICGCPPGFHGPTCRQDV
NECSQNPGLCHHGGTCHNEVGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDT
AHECACLPGFTGQNCEANIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQHCTEDVDEC
QLMPNACQNGGTCHNAHGGYNCVCVNGWTGEDCGENIDDCASASCFHGATCHDRVASFYC
ECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACSQDVDECSLG
ANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICM
PGYEGVHCEVNTDECASSPCLQNGRCLDKINEFVCECPTGFTGHLCQYDVDECASTPCRN
GAKCLDGPNTYTCVCTEGYTGPHCEVDIDECDPDPCHYGSCKDGVATFTCLCWPGYTGHH
CETNINECHSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASNPCDSGTCLDKI
DGYECVCEPGYTGSVCHINIDECADNPCHNGGTCEDGVNGFTCRCPEGYHDPTCLSEVNE
CSSNPCIHGACRDSLNGYKCDCDPGWSGANCDINNDECESNPCVNGGTCRDMTSGYVCAC
REGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYAGATCEVVLAPCAPGPCR
NGGECKESKDYESFSCACPVGWQGQTCEIDINECVKSPCRAGASCQNTNGGYRCHCQAGY
TGRNCETDVDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNPCRNGAN
CTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQ
HDVNECDSRPCLHGGTCHDSYGTYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGRCWQTNA
LYRCECHSGWTGLYCDVPSVSCEVAAWQQGINVTHLCRNGGLCMNVGNTHHCHCQAGYTG
SYCEDQVDECSPSPCQNGATCTDYPGGYSCECVAGYHGVNCSEEVNECLSQPCRNGGTCI
DLTNTYKCSCPRGTQGVHCEINVDDCNPPIDPVSRGPRCFNNGTCVDQVGGYSCTCPPGF
VGERCEGDVNECLSNPCDARGTQNCVQRVNAFHCECRAGHTGRRCESVINGCKDRPCKNG
GSCAVASNTARGFICKCPAGFEGATCENDARSCGSLRCLNGGTCISGPRSPTCLCLGPFT
GPECQFPVGSPCMGGNPCYNQGSCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGVGLD
IPPPQIAEACELPGCREEAGNKVCSLQCNNHACGWDGGDCSLNFNDPWQNCTESLQCWKY
FSNGRCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFRDGHCDQGCNSAECEWDGL
DCAEHVPERLAAGTLVLVVLMPPEQLRNHSLHFLRELSRLLHTNVVFRRDAGGQQMIFPY
YGREGELRKHPIRRSVEGGASRPAGGGGGRRRRELDPMDIRGSIVYLEIDNRQCVQSSSQ
CFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPAPLHFMYVAVVAFVLLFFVG
CGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASDGALVDDNQS
EWGDEGLEAKKFRFEEPVVLPDLDGQTDRRQWTQQHLDAADLRASATAPTPPQGEADTDC
MDVNVRGPDGFTPLMIASCSGGGLETGKSEEEEDAPAVISDFIYQGASLHSQTDRTGETA
LHLAARYSRSDAAKRLLEAGADANIQDNMGRTPLHAAVAADAQGVFQILIRNRATDLDAR
MHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVEAAVVLLKNG
ANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVR
LLDEYSLVRSPPLHGAPTLSPPLCSPSGYLGNLKPAVQGKKARKPSTKGLACGGKEPKDL
RARRKKSQDGRGCLLDSSSALSPVDSLESPHGYLSDVASPPLLPSPFQQSPSMPLNHLPG
MPEAHLGVSHLSVAAKPEMAALSGGGRLAFEAGPPRLSHLPVASGTSTVLGAGGSGSCGG
AVNFTVGGAAGLNGQCEWLSRLQNGLVPNQYNPLRGSVAPGTLSTQAPALQHGMVGPLHG
GLSATALSQMMSYQALPNTRLAAQPHLVQHQQNLQMQPQAPQPHLGVGSATSGHVARSFL
AGELSQADVQPLGPGSLAAHTVLPQDSQVLPTSLPAALAPPMTTAQFLTPPSQHSYSSPV
DNTPSHQLQVPEHPFLTPSPESPDQWSSSSPHSNISDWSEGISSPPTSMPSQIAHVPEAF
K
NT seq
7566 nt
NT seq
+upstream
nt +downstream
nt
atgccgcctctcctggcgcccctgctctgcctggcgctgctgcccgcgctcgccgcacga
ggcctgcgatgttcccagcccagcgagacctgcttgaatggcgggaagtgtgaagtgttc
cccaacggcaccgaggcctgtgtctgcagcggagcctttgcgggccagcgatgccaggcg
cccaacccctgcctcagcgccccctgcaagaatggcgggacgtgccacacggtggagcgc
gacggccttgtggactacacctgccgctgccgcctgggcctctcggggccgctgtgcctg
acgccccgcgaccatgcctgcctcgccagcccctgcctcaacggcggcacctgcgacttg
ctgactctcaccgagtacaagtgcctctgccccccgggctggtcagggaagacatgccag
caggcggacccctgcgcctccaacccctgtgccaacgggggccagtgcctgcccttcgag
gcctcgtacatctgcggctgcccacccggcttccacggccccacctgcaggcaggacgtc
aacgagtgcagccagaaccccgggctctgccaccacggtggcacctgccacaatgaggtc
ggctcctaccgctgcgcctgccgcgccacccacaccggcccccactgcgagctgccctat
gtgccctgcagcccctccccctgccagaacgggggcacctgccgccccacgggggacacc
gcccacgaatgcgcctgcctgccaggcttcaccggccagaactgcgaggcaaacattgac
gactgtccaggaaacaactgcaagaacggaggcgcctgcgtggacggcgtgaacacttac
aactgccgctgccccccggagtggacaggtcagcattgcaccgaggatgtggacgagtgc
cagctcatgcctaacgcctgccagaacggcgggacctgccacaatgcccacggcggctac
aactgcgtgtgcgtcaacggctggacaggcgaggactgcggtgagaacattgatgactgc
gccagtgcctcctgcttccacggtgccacctgccacgaccgcgtggcctccttctactgc
gagtgtccccacggccgcacgggcctgctgtgccacctcaatgacgcctgcatcagcaac
ccctgcaatgagggctccaactgcgacaccaaccccgtcaacggcaaggccatctgcacc
tgccccccgggctacacgggcccggcctgcagccaggacgtggacgagtgctcgctgggc
gccaacccctgtgagcacgcgggcaagtgcatcaacacgctgggctccttcgagtgccag
tgtctgcagggctacaccggcccgcgctgcgagatcgacgtcaacgagtgtgtgtcgaac
ccgtgtcagaacgacgccacctgcctggaccagatcggggagttccagtgcatctgcatg
cccggctacgagggcgtgcactgcgaggtgaacacggacgagtgtgctagcagcccctgc
ctccagaacggccgctgcctagacaagatcaacgagttcgtgtgcgagtgtcccacaggc
ttcaccgggcacctgtgccagtacgacgtggacgagtgtgcaagcacgccctgcaggaat
ggcgccaagtgcctggacgggcccaacacctacacctgcgtgtgcacagaaggctacaca
gggccccactgtgaggtggacattgacgagtgcgaccccgacccctgtcactacgggtcc
tgcaaggacggcgttgccaccttcacctgcctgtgctggccgggctacacgggccaccac
tgcgagaccaacatcaacgaatgccacagccagccctgccgccacgggggcacctgccag
gaccgcgacaatgcctacctctgcttctgcctcaaggggaccacaggccccaactgtgag
atcaacctggacgactgtgccagcaacccctgtgactcgggcacatgtctggataagatt
gacggctacgagtgtgtatgtgagccgggctacacagggagcgtgtgccacatcaacatc
gatgagtgcgcggacaacccctgtcacaacggcggcacctgcgaggacggcgtcaacggc
ttcacctgccgctgccccgagggctaccacgaccccacctgcctgtccgaggtcaacgag
tgcagcagcaacccctgcatccatggggcctgccgggacagcctcaacgggtacaagtgt
gactgtgaccccgggtggagcggggcgaactgtgacatcaacaacgacgagtgtgagtcg
aacccctgtgtcaacggcggcacctgcagggacatgaccagcggctacgtgtgtgcgtgc
cgggaaggcttcagtggccccaactgccagaccaacatcaacgagtgtgcgtctaacccg
tgtctgaaccagggcacgtgtatcgacgacgtggctgggtacaagtgcaactgcctcctg
ccctacgcaggagccacgtgcgaggtggtgctggcgccatgtgcccccggcccctgcaga
aacggcggcgagtgcaaggagtccaaggactacgagagcttctcctgcgcctgccccgtg
ggctggcaggggcagacctgcgagattgacatcaacgagtgcgtgaagagcccgtgccgc
gcaggagcctcctgccagaacaccaacggcggctaccgctgccactgccaggccggctac
acgggccgcaactgcgagacggacgtcgatgactgccggcccaacccgtgccacaacggg
ggctcctgcacagacggcatcaacacggccttctgcgactgcctgcccggcttccagggc
gccttctgcgaggaggacatcaacgagtgcgccagcaacccctgccgcaatggcgccaac
tgcaccgactgcgtggacagctacacctgcacctgccctgcgggcttcagtgggatccac
tgtgagaacaacacgcctgactgcacggagagctcctgcttcaacggcggtacctgcgtg
gacggcatcaactcctttacctgcctgtgtccgccaggcttcacgggcagctactgtcag
cacgacgtcaatgagtgcgactcgcggccctgcctgcacggcggcacctgccacgacagc
tacggcacctacaagtgcacctgcccgcagggctacactggcctcaactgccagaacctc
gtgcgctggtgtgactcctcgccctgcaagaatggcggcaggtgctggcagaccaacgcc
ttgtaccgctgcgagtgccacagtggctggactggcctctactgcgacgtgcccagcgtc
tcctgtgaggtggccgcatggcagcaaggcatcaatgttacccacctgtgccggaacgga
gggctctgcatgaacgtgggcaacacgcaccactgccactgccaagcgggctacacgggc
agctactgtgaggaccaggtagacgagtgctcgcccagcccttgccagaacggggccact
tgcaccgactaccctggtggctactcctgcgagtgcgtggctggctaccacggggtgaac
tgctccgaggaggtcaacgagtgtctgtcccagccgtgccggaatgggggcacctgcatc
gacctcaccaacacctacaaatgctcctgcccccggggcacgcagggcgtgcactgcgag
atcaacgtggacgactgcaacccccccatcgatcccgtgtcccggggccccaggtgcttt
aacaacggcacctgcgtggaccaggtgggcggctacagctgcacctgcccgcccggcttc
gtgggcgagcgctgtgagggtgatgtcaacgagtgcctgtccaacccctgcgacgcccgc
ggcacccagaactgcgtgcagcgcgtcaacgccttccattgcgagtgccgcgccggccac
accgggcgccgctgtgagtcggtcatcaacggctgcaaggacaggccctgcaagaacggg
ggcagctgtgccgtggcctccaacaccgcccgcgggttcatctgcaaatgcccagcgggc
ttcgagggtgccacgtgtgagaacgacgcacgcagctgcggcagcctgcggtgcctcaac
ggcggcacctgcatctcgggcccgcgcagccccacctgcctgtgcctaggccccttcacc
ggccctgagtgccagttccctgtcggcagcccctgcatgggtggcaacccctgctacaac
cagggcagctgcgagcccacgtccgagagccccttctaccgctgcctgtgccccgccaag
ttcaacgggctcctgtgccacatcctggactacagcttcggcggcggcgtgggcctcgac
atccccccgccgcagatcgcggaggcctgcgagctccccggctgccgcgaggaggccggc
aacaaggtctgcagccttcagtgcaacaaccacgcctgcggctgggacggcggcgactgc
tccctcaacttcaacgacccctggcagaactgcactgagtccctgcagtgctggaagtac
ttcagcaacggccgctgcgacagccagtgcaactcggccggctgcctcttcgacggcttc
gactgccagcgcgcagaaggccagtgcaaccccctgtacgaccagtactgcaaggaccac
ttcagggacgggcactgcgaccagggctgcaacagcgccgagtgcgagtgggacgggctg
gactgcgcggagcacgtgcccgagcggctggcggccggcacgctggtgctggtggtgctg
atgccgcccgagcagctgcgcaaccactcgctgcacttcctgcgcgagctcagccgcctg
ctgcacacgaacgtggtcttcaggcgcgacgccggcggccagcagatgatcttcccctac
tacggccgcgagggggagctgcgcaagcaccccatcagacgctctgtggagggcggggcc
tcgcggcccgcgggcggcgggggcgggcgccggcgcagggagctggaccccatggacatc
cgcgggtccatcgtctacctggagatcgacaaccggcagtgcgtccagtcgtcctcacag
tgcttccagagcgccacggacgtggccgccttcctgggcgcgctcgcctcgctgggcagc
ctcaacatcccctacaagatcgaggccgtgcagagtgagacggtggagccgcccccgccc
gcgccgctgcacttcatgtacgtggccgtggtggccttcgtgctgctcttctttgtgggc
tgcggggtgctgctgtcgcggaagcgccggcggcagcatggccagctctggttccccgag
ggcttcaaggtgtcggaggccagcaagaagaagcggcgggagcccctcggcgaggactcc
gtgggcctcaagcccctgaagaacgcctcggacggcgccctcgtggacgacaaccagagc
gagtggggcgacgagggcctggaagccaagaagttccggttcgaggagcccgtggtcctt
cccgacctggacggccagacagaccgccggcaatggacccagcagcacctggacgctgct
gacctccgcgcgtccgccacggcccccacgccgccccagggcgaggctgacaccgactgc
atggacgtcaacgtccgtgggccggacggcttcacgcccctcatgatagcctcctgcagc
ggagggggcctggagaccggcaagagcgaggaggaggaggacgcacccgccgtcatctcg
gacttcatctaccagggcgccagcctgcacagccagacggaccgcaccggcgagaccgcc
ctgcacctggccgcccgctactcgcgctccgacgcggccaagcgcctgctggaggccggc
gctgacgccaacatccaagacaacatgggacgcaccccgctgcacgcggccgtggctgcc
gacgcgcagggtgtctttcagatcctcatccggaaccgagccacggacctggacgcccgc
atgcacgacggcacaactccactgatcctggccgcccgcctggccgtcgagggcatgctg
gaggacctcatcaactcccacgccgacgtcaacgccgtggacgacctgggcaagtccgcc
ctgcactgggccgccgcggtgaacaacgtggaggccgccgtcgtgctcctgaagaatggg
gccaacaaggacatgcagaacaacaaggaggagacgcctttgttcctggccgcccgggag
ggcagctacgagacggccaaggtgctgctggaccatttcgccaaccgggacatcacggac
cacatggaccgcctgccccgtgacatcgcgcaggagcgcatgcaccacgacatcgtgcgg
ctactggacgagtacagcctggtgcgcagccccccgctgcacggcgcgcccaccctgtcg
ccccctctctgctctcccagcggctacctgggcaacctcaagcctgccgtgcagggcaag
aaggcccgcaagcccagcaccaagggcctggcctgcggcggcaaggagcccaaggacctc
agggcgcggaggaagaagtcccaggacggcaggggctgcttgctggacagctcgagcgcg
ctgtcgcccgtggactccctggagtccccccacggctacctgtcggatgtggcctcccca
cccctcctgccctcccctttccagcagtctccctctatgcccctcaaccacctgcccggg
atgcccgaggcccacctgggcgtcagccacctgagcgtggcggccaagcccgagatggcg
gcgctgagtgggggtggccggctggccttcgaggcggggccaccacgcctctcccacctt
cccgtggcttccggcaccagcacggtcctgggtgccggtggcagcgggagctgcggtggg
gccgtgaatttcaccgtgggcggggccgcaggcttgaacggccagtgcgagtggctgtcc
cggctgcagaatggcctggtgccaaaccagtacaacccgctgcgagggagcgtggcgccg
ggcaccctgagcacgcaggcccccgccctccagcacggcatggtgggcccgctgcacggc
ggcctgtctgccaccgccctgtcccagatgatgagctaccaggccctgcccaacacgcgg
ctggccgcccagcctcacctggtgcagcaccagcagaacttacagatgcagccgcaggca
ccgcaaccgcacctcggcgtgggctcggccaccagcggccacgtggcccggagcttcctg
gcgggggagctgagccaggcggacgtgcagcccctgggccccggcagcctggcggcgcac
accgtcctgccgcaggacagccaggtcctgcccacatcgctgccggccgcgctggccccg
cccatgaccaccgcccagttcctgacgcccccctcccagcacagctactcctcccccgtg
gacaacacccccagccaccagctgcaggtgcccgagcaccccttcctcaccccgtccccg
gagtcccccgaccagtggtccagctcatcgccacactccaacatctccgactggtccgag
ggcatctccagcccgcccaccagcatgccgtcccagatcgcccacgttcctgaggccttt
aagtga
DBGET
integrated database retrieval system
