Delphinapterus leucas (beluga whale): 111177098 Help Entry 111177098         CDS       T05885                                  Symbol SETX Name (RefSeq) probable helicase senataxin   KO K10706   ATP-dependent RNA/DNA helicase, senataxin [EC:5.6.2.5 5.6.2.3] Organism dle  Delphinapterus leucas (beluga whale) Pathway dle05014   Amyotrophic lateral sclerosis Brite KEGG Orthology (KO) [BR:dle00001]  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     111177098 (SETX)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03021 Transcription machinery [BR:dle03021]     111177098 (SETX) Enzymes [BR:dle01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      111177098 (SETX)     5.6.2.5  RNA 5'-3' helicase      111177098 (SETX) Transcription machinery [BR:dle03021]  Eukaryotic type   RNA polymerase II system    Other transcription-related factors     Transcription termination factor      111177098 (SETX) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_11 AAA_12 UvrD-helicase AAA_19 AAA_30 AAA_22 ResIII SLFN-g3_helicase AAA_16 nSTAND3 Helicase_RecD UvrD_C_2 Tubulin Motif Other DBs NCBI-GeneID:  111177098 NCBI-ProteinID:  XP_022434060 UniProt:  A0A2Y9NMF6 LinkDB All DBs Position Unknown AA seq 2685 aa AA seqDB search MSTCCWCTPGGISTIDFLQHYASETHSSEFRTADEDLCYCLECVAEYHKARDELPFLHKV LWELETSRLINHFEKAMKAEIGDDDELYIVDNNGEAQPFDFTGQDFENKLRVPLLEILKY PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDATNYKNYWLG ICMLLTILEEQAMDSLLLGSNKQTDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL GSKVWGQLIDPIEAFQTIINNVSYNKEIQNIRNSSMRTKFEPESYLDDVTCSQIVYNYNP EKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFVPFVQSLLEL KDLGVAYVVAVIHHLHSEVKGALSQAGAVCDTVTEFFLLILVSVIELHRSKKCLHLLWVS SQQWVEAIVKCAKLPTTAFARTSEKSSGNCSKGTMISSLSLHSAPCNSVQLACVQLIRSL LKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKFKVPQC STSVDLTSPCKMPPASYNKEESEQTRKKSRKDRHCLENSSPTFSKEPMKADACQVQESIF SKANNAIEEDNEQTYIKDLKLKDHLSAELCLKPSSKRIVNERARGQVKISTGKHKSVKEN SSYTPQNCTSGNGPEKVFDRGIITSTRLLTDSSNDSLEKVSTSNEDFSLKGDALGKTSKA KTKAHKDEICAKLSHVIKKQHRKSITLEENLTVSSIESVYSKKDTGGQKGDGFIYNLSLG PDGTLDDKNGEQKSEKSLLLKKKQVQEEELGIFSTRELSCQILECHVGNKDLVSFTETTN IFVEKTPPFKDPVTGLESRDMEIIKSTAQFSSDLREQALSISPKSDTLTDSQIDRDLHKL SLVAQASVIKFPSDSTQKSLSQLQRKVKDDRRCFTANQNSVRETCCGQVIIISDSDEEDN DDEERIVGFKKHITQDKTCIEKECPEQHASIANTNVEQKVIREENTGSLLQFEESDSQFF EFESPCEVFSVWQDQKPDNKNSVQENEENSCLTHAGDTTNDWGYGTDDVPEEVIKKAAEG IEEHAEPHSSSISVEKFCEIEVKKPKRRRYQKAAMAEDPLRPSSPVKSEDQSDILNERDV TENDFKSIDVRTTTPSSSVQRTTTVSLKKSPPKLRTYSKRVRRVSLSKTPKKTRSDTKTG QSKSSNYLSCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKAPRRAFELSQRSLECLAQLRD HGKTVGAVDTRKKTKLISPQTLSVRNNKKLLTSQDLQLQRQMRPKSQRNRQRCFDYQSTD RTRAGPPGAQNSDECVPESDTSDYSYKGGVEVTAKSKEKELIKCVSSETEPVKAKYVSQV ADGTCLLNPCTSVVLNGEVPTNEIVVSTSGDPLGGGDLTVHHLGVAALREGDPESSSDIE EDNIFLTQRDPEDMDLCSQMEKENDKLIEVVHGKDTVQVEEDSVSRPQLESLSSTKCKYK GCVETLKNQGEYCSKHSEAKAADEDIFRKPGLPLSASKPSRPPTAKIFSSSSTSRIAGLS KSLENTAALLPMLKNKSSGVQSVLKVPPVSLVSKKPVAEVKGLCNVLHSHTPNNSNRQGY KVPFCENRSFSASPPVNVLLSAQSISDTFVKEVLKWKYEMFVNFDQCGPPSALCESISRP VPVRFQDGGDYFEVFFPLMMLNTFETVAQEWISSPNKEKFHQLHLRKFPSEYKKYWEFVV YLEECELAKQLHPKENDLVFLIPEKLNGEEEDIERNRMQDPYEYYCGYVHKFRRTSVMHS GKYECSVSIQTQRNLPVNLNEFVKCLVISSLVTTQRKLKAMSLLSGRNQLARAILNPNPM DFCTKDLLTTASEKIIAHLKDFNEDQKKAIETAYAMVKHSPAVAKICLIHGPPGTGKSKT IVGLLYRLLTERRGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILQFKEKCKDKKNP LGNCGDINLLRLGPEKSINAEVLKFSLDSQVNHRMKKELPSHIQEMHRRKEFLDHQLDEL SRQRALCRGGRELQRQELDEKIAKVSKERQELASKVKEVQGRPQKTQNTIILESHVICCT LSTSGGLLLEAAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPT VISVKAQEYGYDQSMMARFYKLLEENVKHNVIGRLPVLQLTVQYRMHPDICLFPSNYVYN RNLKTNRMTEAIRCSSDWPFQPYLVFDVGDGSEKRDNDSYVNVQEIKLVMELVKLMKDKK RDFTYRNVGIITHYKAQKMMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANA MQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENYHWNQLIQDAQKRGAIVKTWDKN YRQDAVKILKLKPVLQRSLTHPPAIAPEVSRPQGGMPSNKLDSEFAKMSIASSLYPSPSD SKEGTVTVTANDPERPPIQDWLRDPRLLRRMGLGCEAKGKCLSELQPSSPQYPGATPPSG EPGSPGRHQDLTSIGQQPPAKGAAVNNHRPHAQCDPPAASTDASTSKRKCAQEGEAVSHR RETRAFPEGDQETCGSLSHHTKRNSGWDERGLEEEDSSLKKRKLL NT seq 8058 nt NT seq  +upstreamnt  +downstreamnt atgagcacatgttgttggtgtacaccaggtggtatttccaccattgacttcctgcaacac tatgcatccgagacccactccagtgaatttcgaacagctgatgaagacctctgctactgc ttagagtgtgtggctgaataccacaaagcaagggatgaattgccattcttacataaggtt ttatgggaattagaaacctcacgtctcataaatcactttgaaaaggccatgaaggcagaa attggagacgatgacgagttatatatagtagacaacaatggagaggcacagccgtttgac tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat ccttatttgcttttacatgagcgtgttaatgaactatgcgttgaagcactttgccggatg gaacaagctaactgctcctttcaggtttttgacaaacatccagggatctatttgtttttg gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaagaaacttgggaaaa gtggacagagatgattattatgacttacaggaggttttgacttgcctttttaaagtcatt gagttggggcttttagaaagtccagacatttatacttcttctgtccttgagaagggtaaa ctgattcttctgccttcacacatgtatgatgctaccaactacaaaaactattggttaggt atttgcatgttgctgaccattcttgaggagcaagccatggattcactgttgttgggctca aacaaacagactgattttatgcaatcaatacttcacaccatggagaggcaatcagatgat gatagtgtggatcctttctggccagcgttacactgtttcatggtgattctggatcgcctc ggatccaaggtctggggtcaacttattgatcctattgaggcatttcaaaccattatcaac aatgtgagctacaataaagagattcagaatatacggaacagctctatgaggaccaagttc gaaccagagtcatatttggatgatgtgacttgcagccagatcgtatacaattataaccct gaaaagaccaaaaaggattcagggtggagatcggccatttgcccagattattgtcctaac atgtatgaagaaatggaaacactagctaatgtgctgcagtcagatatcggtcaagacatg cgtgttcataacagcacgtttctgtggttcgtcccgtttgtgcagtcgctcctggagctt aaggacctgggcgtggcgtatgtggtggcggttatccatcacctgcactccgaagtcaag ggcgccctcagccaggcaggcgccgtgtgcgacaccgtcactgagttcttcctcctgatt ttggtgtcagtgattgagctgcacagaagtaaaaagtgtttgcatttgctgtgggtgagc tcccagcagtgggtggaagccattgtaaaatgtgccaagcttcccaccaccgcgtttgca cggacttctgagaagtcatctggaaactgctccaaaggcacgatgatatcatctctgtca ttgcattcagcgccatgtaactctgtacaacttgcttgtgtgcagctgatcagaagtctc cttaaagaaggctatcagcttgggcagcagacgctttgtaagcgattctgggataagctc aacttattcctgcgaggaaatttatctttaggttggcagttgaccagtcaggaaacccat gagttacaaacttgtttaaagcaaattattagaaacataaaattcaaagtacctcaatgt agcacttctgtggatctgacttctccatgtaaaatgcctcctgcatcatataataaagaa gaaagtgaacaaacaaggaagaagtctagaaaagacaggcactgtctggaaaactccagc ccaacattctctaaagaaccgatgaaagctgatgcatgtcaagtgcaagagagtattttc agcaaagcaaataatgccatagaagaggataatgagcaaacttatataaaagatttgaaa ctcaaagaccatctctcagctgagttgtgcttgaagccgagtagtaaaaggattgttaat gaaagagctcgaggccaagttaaaataagtacagggaagcataagtctgtaaaagagaat tcctcatataccccacagaattgtacttcaggaaatggtccagaaaaggtatttgacaga ggaataataacatcaacacgtttgttgactgattctagcaatgactctctggaaaaggtg tccacatcaaatgaggatttctctttaaagggtgatgctcttggcaaaacctcaaaagca aaaactaaggcacataaagatgaaatctgtgctaagttatcacatgtaataaaaaagcaa cacaggaaaagtatcactttagaggaaaacctgactgtatctagcattgaaagtgtctat tcaaagaaggatacaggaggtcagaaaggagatggcttcatatacaatctctctttaggc cctgatggtactctggatgataaaaatggagaacaaaaatctgaaaagagtttattgctg aaaaagaaacaagtacaggaagaagagttaggcattttctctacccgtgaactcagttgt caaatactagaatgtcatgttggtaacaaagatttggtctcatttacagaaacgaccaat atttttgtggagaaaacacctccctttaaagatcctgtgactggacttgaatcaagagat atggaaattatcaagagtactgctcagttttcttctgatttaagagagcaagcccttagc atcagtcctaagtctgacaccttaacagattctcagatagacagagacctccacaaatta tccttagtagctcaagccagtgttattaagttcccatcagattcaactcaaaaaagttta tcccagctacaaagaaaagttaaagatgatagaagatgtttcacagccaaccaaaatagc gttagggaaacctgctgtggacaggtcattattatttcagattctgacgaagaagataat gatgatgaggaaagaattgtgggttttaagaaacacattacacaggataaaacatgcatt gagaaagaatgtccagagcagcacgcttcaatagctaacacaaacgtggaacagaaggta ataagggaagaaaataccgggtcccttttgcagtttgaggaatctgattctcagtttttt gagtttgaaagtccatgtgaagtgttttcagtttggcaagatcagaaaccagacaacaag aattcagttcaagagaatgaagaaaattcgtgcttgactcatgcaggtgataccacaaat gattggggttatggtacagatgatgtacctgaagaggtcattaaaaaagcagcagagggc attgaggaacacgcagaaccacacagtagtagtatttctgttgagaagttttgtgagatt gaagtaaaaaaacccaagagaaggcgatatcagaaagctgctatggctgaagatcctcta aggccttcatctcctgtcaaaagtgaggaccagtccgatattcttaatgagagagatgtg accgaaaatgattttaaaagtatagacgtaaggactacaactcccagttcgagcgttcag agaaccactacggtttccctgaagaagtctccaccaaagcttcgcacttactccaaacgt gttaggagagtctcactttctaaaactcctaaaaaaacacgttcggataccaaaacaggg cagagtaaaagttcaaattacctaagttgtagaacaactcctgctatagtgccaccaaag aaatttcgccagtgtcctgaaccaacttcaacggttgagaaacttggtctgaaaaaggct cctcgtagggcatttgagttgtcccagcgatctttggagtgtttggctcagttacgtgac catggcaaaactgttggagcagttgatacccggaaaaagactaaattaatttctcctcag actctctctgtcagaaataataagaaactgctgacgagtcaagaccttcagctgcaaagg cagatgagacccaaatcacagcgtaacagacaaagatgttttgattatcagagtacagat agaacacgagcaggcccacctggagcacagaattctgacgaatgtgtgccagaatcagat acatcagattatagttacaaaggaggagttgaggtaactgctaaaagtaaggaaaaagag ttaataaagtgtgtgtcttctgaaacagaacccgtgaaagcaaaatacgtttctcaggta gctgatggcacttgtcttttgaacccgtgcacttctgtagtattaaatggagaagtacca acaaatgaaatagttgtttctacctcaggggaccctttaggtggaggtgacctaacagta catcatttaggtgtggcagccttgagagagggagatcctgaatccagcagtgacatagag gaagataatatatttttaacacaacgtgatcctgaagatatggatttatgttcacaaatg gagaaagagaatgataaactcattgaagtagttcatggaaaagatacagtccaggtagaa gaagattctgtgagtcggcctcagttggaatctttgagtagcacaaaatgtaaatacaaa ggttgtgttgaaacactgaaaaaccagggtgaatactgttcaaaacactctgaagctaaa gcagcggatgaagatatatttcgtaaacctggcttgcctctctctgcatctaaaccttcg agacctcccactgctaagatttttagctccagtagtacttcacgaattgctggcctttcc aagtctttggaaaatacggcagcgctcttaccaatgctgaaaaataagtcaagtggggta cagtctgttttgaaagtaccgccagtctctctggtgtccaagaagccagtggctgaagtg aagggtttgtgcaacgttctccattctcatactccaaataattccaacaggcaaggctac aaagttccattttgtgaaaacagatctttttcggcttcccctccagtaaacgttctcttg tcagcacagtccatctctgacaccttcgttaaagaggtcttaaaatggaaatacgaaatg tttgtgaactttgatcagtgcggacccccgtcagctctttgtgagtccatctcaagacct gtgcctgtgagatttcaagatggtggagattattttgaagtgtttttccctttgatgatg ctgaatacttttgaaacagtggcacaggaatggatcagctctccaaacaaagagaaattc catcagttgcatttacgaaaatttccttctgagtataaaaaatactgggagtttgtggtt tatcttgaggaatgtgaactagctaaacagcttcatccaaaggaaaatgatttggtgttt ttgattcctgaaaaactaaatggagaggaggaggacatagagagaaatcgcatgcaagat ccctatgaatattattgtggttatgttcataaattccgccgcacttcagtcatgcatagt gggaaatatgagtgctccgtttccatccagactcaacgtaatttaccagtcaatttaaat gaattcgtgaaatgtcttgtaatcagctctctggtgactacacaaaggaagttgaaagcc atgtctttgctgagtggtcggaaccaactggccagagccattctgaatccaaaccccatg gacttctgtacaaaagatttactaactacagcatctgagaaaattattgcccacctaaaa gatttcaatgaagaccaaaagaaagcaatagaaactgcatatgccatggtgaaacactcc ccagcagttgccaagatctgtctgattcatggaccacccgggacaggaaaatcaaaaacc attgtgggcctcctgtaccgcctactgacagagaggaggggacattcagatgagaactcc aatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcgccttccaatgcagctgttgat gaacttatgaaaaaaattatccttcaattcaaagagaagtgtaaagacaagaagaatcct ttgggaaactgtggagatataaatttactacgtctaggtccagaaaagtctattaatgct gaggtcctaaaattcagtttggacagccaagttaaccacagaatgaaaaaagaattacct tctcatattcaggagatgcatagaagaaaggaatttctagatcatcaactagatgaactt tcccgccagcgtgctttatgccgaggtggaagggaactacagaggcaagaattagatgaa aaaattgccaaggtttcaaaagaaaggcaggagcttgcttctaaagttaaagaggttcaa ggacgcccacagaagacacagaacaccatcatcttagagtcccacgtcatctgctgcaca ctgagcacgagtgggggcctgctgctcgaggctgctttccgtgggcagggcggcgtcccc tttagttgcgtcattgttgacgaggccggacagtcttgtgaagttgaaactcttactcca ctcatccatcgttgcaacaagctcatcctcgtaggagatcctaagcagctccctcccaca gtcatttctgtgaaggcccaggagtatggctatgaccagtcgatgatggcccgcttctac aaacttctggaagagaacgtgaagcacaacgtgattggcaggctgcctgtcttacagctc accgttcagtacaggatgcacccagacatatgtctcttcccttctaattacgtttataac aggaacttgaaaacaaatagaatgacagaggccattcggtgttcatctgactggccattt caaccctacctcgtgtttgatgttggagatggttcagaaaagcgggataatgactcatat gtaaatgttcaagaaataaaactggtaatggaactagttaaacttatgaaagacaaaaaa agggattttacttaccgaaacgttggcataataacccattacaaggctcagaagatgatg attcagaaggatttggacaaagagtttgatagaaaagggccagcggaagtagataccgtg gatgccttccagggtcgtcagaaagattgtgttattgttacatgtgtcagagcaaatgcc atgcaaggttcaattgggtttctggcaagtttgcagagattgaacgtcaccatcacacga gccaagtacagcctcttcatcctgggacatttgaggaccctgatggaaaactatcattgg aatcagctgattcaggatgcgcagaagcgtggtgccatcgttaagacttgggacaaaaac tatagacaagatgcagtgaagattctgaaactcaagcccgtactgcagagaagtctgact caccctcctgctatcgccccagaggtgtccagaccccagggcggaatgcccagcaacaag ctagacagtgaatttgccaagatgtctattgcttcttccctgtacccctcaccctctgac tccaaagaaggcactgtcactgttactgcaaatgaccctgaaaggccacccattcaggac tggcttcgggacccacgactacttaggaggatgggcttgggctgtgaagccaaagggaaa tgcctcagtgagctgcagccctcgagcccccagtatcccggagcaacgcctccctctgga gagccaggctcccccggaaggcaccaggatctgaccagtatcgggcagcagccccccgcc aagggagctgctgtgaacaaccacagacctcacgcgcagtgcgaccctccagctgctagt accgatgcttccacgagtaagagaaaatgtgcccaggaaggggaggcagtcagccacagg agggagaccagggccttccctgagggggatcaggagacgtgtggctctctgagccaccac acaaagaggaactcaggctgggacgagagggggctggaggaggaggacagtagcttgaag aagaggaagcttttatag

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