Delphinapterus leucas (beluga whale): 111177192
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Entry
111177192 CDS
T05885
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle00790
Folate biosynthesis
dle01100
Metabolic pathways
dle01240
Biosynthesis of cofactors
dle01523
Antifolate resistance
dle04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
111177192 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
111177192 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
111177192 (FPGS)
Enzymes [BR:
dle01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
111177192 (FPGS)
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Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
111177192
NCBI-ProteinID:
XP_022434370
UniProt:
A0A2Y9NK02
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Position
Unknown
AA seq
580 aa
AA seq
DB search
MSRARCHLRAALFLAEVSSRGATTGVAARRVLSAWPAPQEPGMEYQDAVRTLNTLQTNAN
YLEQVKRQRGDPQTQLEAMRLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWCLYHRLEETKDDSSCVSMPGYFR
FLTLMAFHVFLQEKVDLAVMEVGIGGAYDCTNIVKKPVVCGVSSLGIDHTGLLGDTMEKI
AWQKGGIFKSGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPLLTLGLEG
EHQQANAALALQLARCWLQQKGYRDTGELKASRPSLLGQLPLAPVFQPTSHMQHGLRDTE
WPGRTQLLRRGPLTWYLDGAHTTSSMQACVRWFRQALQSRERPGGGSEVRVLLFNSTGDR
DSAALLKLLQPCQFDYTVFCPNLTEVSSTDNADQQNFTVTLDQVLLRCLAHQQHWSRLHE
DQASPEPGGPAPLLLAPRPAHTHSASSLVFSCISHALQWISQGRDPVFQPPSPPRVLFAH
PVAGSGAVVLQEAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcacgctgccacctgcgcgcggctctcttcctggcagaggtttcttcgcgt
ggtgcaacaaccggggtcgcagcgaggcgagtattgagcgcgtggcctgcgccgcaggag
cccggcatggagtatcaggatgccgtgcgcacactcaacaccctgcagaccaatgccaac
tacttggagcaggtgaagcgccagcggggtgacccccagacacaactggaagccatgagg
ctgtacttggcacggagtgggctgcaggtggaggacttggaccaactgaacatcattcac
atcactgggaccaaggggaagggctccacctgtgccttcactgaacgtatcctccgaagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggtgcgtgagcggatc
cgaatcaatgggcagcccataagccctgagctcttcaccaagcacttctggtgcctctac
caccggctggaggagaccaaggatgacagcagctgtgtctccatgcctggctacttccgc
ttcctcacactcatggccttccatgtcttcctccaagagaaggtggacctggcagtgatg
gaagtgggcatcggcggggcttacgactgcaccaacatcgtcaagaagcctgtggtgtgt
ggggtctcctctcttggcatcgaccacactggccttctgggggacacgatggagaagatc
gcatggcagaaagggggcatttttaagagtggcgtccccgccttcactgtgctccagcct
gacgggcccctggcagtgctgagggaccgcgctcagcagatctcatgtcccctctacctg
tgcccaccactagaagccctggaggaaggggggccgctgctgaccctgggcctggagggg
gagcaccagcaggccaatgccgccttggccttgcagctggctcgctgctggctgcagcag
aagggctaccgggatactggagagctgaaggcatccaggccaagcctcctggggcagctg
cccctggcacctgtgttccagcccacgtcccacatgcagcatgggcttcgggacacggag
tggccgggccggacgcagttgctgcggcggggccccctcacttggtacctggacggcgcg
cacaccaccagcagcatgcaggcctgcgtgcgctggttccgccaggcgctgcaaagccgc
gagaggccgggcggcgggtctgaggtgcgtgtcttgctcttcaactccactggggaccgg
gattccgcggccctgctgaagctgctgcagccctgccagtttgactataccgttttctgc
cctaacctgacagaggtgtcatccacggacaacgcagaccaacagaacttcacagtgacc
ctggaccaggtgctgctccgctgccttgcgcaccagcaacactggagccgcctgcacgag
gaccaggccagcccggagcctggtgggcctgcacccctgctgctggcaccccgcccagcc
cacacccacagcgccagctccctcgtcttcagctgcatttcccacgccttgcagtggatc
agtcaaggccgggaccctgtctttcagccacccagtcccccacgggtcctctttgcccac
cctgtggcaggcagtggggccgtcgtcctccaggaggctgctgccatccacgtgctggtc
acaggcagcctgcacctggtgggcggcgtgctgaagctgctggagccctccctgtcccag
tag
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