KEGG   Delphinapterus leucas (beluga whale): 111179107
Entry
111179107         CDS       T05885                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle04010  MAPK signaling pathway
dle04020  Calcium signaling pathway
dle04022  cGMP-PKG signaling pathway
dle04114  Oocyte meiosis
dle04218  Cellular senescence
dle04310  Wnt signaling pathway
dle04360  Axon guidance
dle04370  VEGF signaling pathway
dle04380  Osteoclast differentiation
dle04625  C-type lectin receptor signaling pathway
dle04650  Natural killer cell mediated cytotoxicity
dle04658  Th1 and Th2 cell differentiation
dle04659  Th17 cell differentiation
dle04660  T cell receptor signaling pathway
dle04662  B cell receptor signaling pathway
dle04720  Long-term potentiation
dle04724  Glutamatergic synapse
dle04728  Dopaminergic synapse
dle04921  Oxytocin signaling pathway
dle04922  Glucagon signaling pathway
dle04924  Renin secretion
dle05010  Alzheimer disease
dle05014  Amyotrophic lateral sclerosis
dle05020  Prion disease
dle05022  Pathways of neurodegeneration - multiple diseases
dle05031  Amphetamine addiction
dle05152  Tuberculosis
dle05163  Human cytomegalovirus infection
dle05166  Human T-cell leukemia virus 1 infection
dle05167  Kaposi sarcoma-associated herpesvirus infection
dle05170  Human immunodeficiency virus 1 infection
dle05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dle05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111179107 (PPP3CA)
   04310 Wnt signaling pathway
    111179107 (PPP3CA)
   04370 VEGF signaling pathway
    111179107 (PPP3CA)
   04020 Calcium signaling pathway
    111179107 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    111179107 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    111179107 (PPP3CA)
   04218 Cellular senescence
    111179107 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    111179107 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    111179107 (PPP3CA)
   04660 T cell receptor signaling pathway
    111179107 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    111179107 (PPP3CA)
   04659 Th17 cell differentiation
    111179107 (PPP3CA)
   04662 B cell receptor signaling pathway
    111179107 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    111179107 (PPP3CA)
   04921 Oxytocin signaling pathway
    111179107 (PPP3CA)
   04924 Renin secretion
    111179107 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    111179107 (PPP3CA)
   04728 Dopaminergic synapse
    111179107 (PPP3CA)
   04720 Long-term potentiation
    111179107 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    111179107 (PPP3CA)
   04380 Osteoclast differentiation
    111179107 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111179107 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    111179107 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    111179107 (PPP3CA)
   05163 Human cytomegalovirus infection
    111179107 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111179107 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    111179107 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    111179107 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    111179107 (PPP3CA)
   05020 Prion disease
    111179107 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    111179107 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    111179107 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    111179107 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:dle01009]
    111179107 (PPP3CA)
Enzymes [BR:dle01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     111179107 (PPP3CA)
Protein phosphatases and associated proteins [BR:dle01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     111179107 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 111179107
NCBI-ProteinID: XP_022438138
UniProt: A0A2Y9P7D5
LinkDB
Position
Unknown
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDTNLNSINKTLASETNGTDSNGSNNSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gtcccgtttcctccaagtcaccggcttacggcaaaagaagtgtttgataacgatgggaaa
cctcgtgtggatatcttaaaggcacatctcatgaaggagggcaggctggaagagagtgtt
gcattgagaataatcacagagggggcttcaattcttcgacaggaaaaaaatttgctggat
attgatgcaccagtcacagtttgcggggacatccatggacaattctttgacttgatgaag
ctctttgaagtgggcggatctcctgccaacactcgctacctcttcttaggggactatgta
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggctttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgcatggat
gcctttgactgcctgcccctggctgccctgatgaaccaacagttcctatgtgtacacggc
ggtttgtctccagagattaacaccttagatgatatcagaaaattagaccgattcaaagaa
ccacccgcttatggacctatgtgtgatatcctgtggtcagaccccctggaggattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatactccgagcc
catgaagcgcaagacgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctcattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgtcatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgttttcacttggtccctgccgtttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagatgatgaactggggtcagaa
gaagatggatttgatggtgcaacggctgcagcccgcaaggaagtgatacggaacaagatc
cgagcgatcggcaagatggccagagtgttctccgtgctcagagaagagagcgagagtgtg
ctgacgctgaaaggcctgacgcccacgggcatgctccccagtggagtgctctctggaggg
aagcaaaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggcttagatcgaattaac
gagaggatgccacctcgcagagatgccatgccctctgacaccaaccttaactccatcaac
aagactctcgcctcagagactaacggcacggacagcaatggcagtaataacagcaatatc
cagtga

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