Delphinapterus leucas (beluga whale): 111179463
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Entry
111179463 CDS
T05885
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle00562
Inositol phosphate metabolism
dle01100
Metabolic pathways
dle01521
EGFR tyrosine kinase inhibitor resistance
dle04012
ErbB signaling pathway
dle04014
Ras signaling pathway
dle04020
Calcium signaling pathway
dle04062
Chemokine signaling pathway
dle04064
NF-kappa B signaling pathway
dle04066
HIF-1 signaling pathway
dle04070
Phosphatidylinositol signaling system
dle04072
Phospholipase D signaling pathway
dle04360
Axon guidance
dle04370
VEGF signaling pathway
dle04380
Osteoclast differentiation
dle04611
Platelet activation
dle04613
Neutrophil extracellular trap formation
dle04625
C-type lectin receptor signaling pathway
dle04650
Natural killer cell mediated cytotoxicity
dle04662
B cell receptor signaling pathway
dle04664
Fc epsilon RI signaling pathway
dle04666
Fc gamma R-mediated phagocytosis
dle04670
Leukocyte transendothelial migration
dle04722
Neurotrophin signaling pathway
dle04750
Inflammatory mediator regulation of TRP channels
dle04919
Thyroid hormone signaling pathway
dle04933
AGE-RAGE signaling pathway in diabetic complications
dle04935
Growth hormone synthesis, secretion and action
dle05167
Kaposi sarcoma-associated herpesvirus infection
dle05169
Epstein-Barr virus infection
dle05170
Human immunodeficiency virus 1 infection
dle05171
Coronavirus disease - COVID-19
dle05200
Pathways in cancer
dle05205
Proteoglycans in cancer
dle05206
MicroRNAs in cancer
dle05214
Glioma
dle05223
Non-small cell lung cancer
dle05225
Hepatocellular carcinoma
Module
dle_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
111179463 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
111179463 (PLCG2)
04014 Ras signaling pathway
111179463 (PLCG2)
04370 VEGF signaling pathway
111179463 (PLCG2)
04064 NF-kappa B signaling pathway
111179463 (PLCG2)
04066 HIF-1 signaling pathway
111179463 (PLCG2)
04020 Calcium signaling pathway
111179463 (PLCG2)
04070 Phosphatidylinositol signaling system
111179463 (PLCG2)
04072 Phospholipase D signaling pathway
111179463 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
111179463 (PLCG2)
04613 Neutrophil extracellular trap formation
111179463 (PLCG2)
04625 C-type lectin receptor signaling pathway
111179463 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
111179463 (PLCG2)
04662 B cell receptor signaling pathway
111179463 (PLCG2)
04664 Fc epsilon RI signaling pathway
111179463 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
111179463 (PLCG2)
04670 Leukocyte transendothelial migration
111179463 (PLCG2)
04062 Chemokine signaling pathway
111179463 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
111179463 (PLCG2)
04919 Thyroid hormone signaling pathway
111179463 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
111179463 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
111179463 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
111179463 (PLCG2)
04380 Osteoclast differentiation
111179463 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111179463 (PLCG2)
05206 MicroRNAs in cancer
111179463 (PLCG2)
05205 Proteoglycans in cancer
111179463 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
111179463 (PLCG2)
05214 Glioma
111179463 (PLCG2)
05223 Non-small cell lung cancer
111179463 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
111179463 (PLCG2)
05171 Coronavirus disease - COVID-19
111179463 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
111179463 (PLCG2)
05169 Epstein-Barr virus infection
111179463 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
111179463 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111179463 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dle04131
]
111179463 (PLCG2)
Enzymes [BR:
dle01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
111179463 (PLCG2)
Membrane trafficking [BR:
dle04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
111179463 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
111179463 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
C2
SH3_1
PH
SH3_9
PH_12
SH3_2
PH_14
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
111179463
NCBI-ProteinID:
XP_022438794
UniProt:
A0A2Y9NXP3
LinkDB
All DBs
Position
Unknown
AA seq
1265 aa
AA seq
DB search
MSTTVNVDALPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETQQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEECCFTILYGTQFVLSTLSLAADSKEDAT
KWLSGLKILHQEVMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSSA
KFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKLILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDVQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCLQQQRHMARV
FKEAFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHRQQGE
LYMWDSIDQRWTRHYCAIADAKLSFSDDIEQTTEGEQPPDIAPTELHFGEKWFHKKVEKR
TSAEKLLQEYCAETGGKDGTFLVRESETYPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYY
LTDNLMFTSIYALIQHYSETHLRCAEFELRLTDPVPNPSPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMKLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEISPSMPQRTVKALYDY
KAKRNDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADGEDLEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDKVEELFEWF
QSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSIVRQKPNDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKY
LQMNHALFSLNGRTGYVLQPESMRAEKYDPMPPESQRKILMTLTVKVLGARHLPKPGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATFPIKGIKSGFRSVPLKNGYSEDMELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRSANRDALVREFNVNENQLQLYQEKCNRRLREKRVSN
SKFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccacggtcaacgtggacgcccttccggagtacgagaagagtcagatcaagagg
gccctggagctgggcacggtgatgacggtgttcagcttccgcaagtccaccccggagcgg
aggactgtccaggtgatcatggagacccagcaggtggcctggagcaagacggccgataag
atcgagggcttcctggatatcatggaaataaaggaaatccgcccagggaagaactccaag
gattttgagcgtgcgaaagcagtccgtcagaaggaagagtgctgcttcaccatcttgtat
ggcacccagttcgtcctcagcacgctcagcttagcagccgactctaaagaagatgcaact
aagtggctctctggcttgaagatcttgcaccaggaagtgatgaacgcatccacccccacc
atcattgagagttggttgcgaaagcagatttattctgtggatcagaccagaagaaacagc
atcagcctccgagagttgaagaccatcttgcccctggtcaacttcaaagtgagcagcgcc
aagttcctcaaagataagttcgtggaaataggagcacacaaagatgaactcagctttgaa
cagttccatctcttctataaaaaacttatgtttgaacagcagaaattgattcttgacgaa
ttcaaaaaggattcctccgtgttcatcttgggcaacaccgaccggccggatgcctccgct
gttcacctgcatgacttccagcggtttctcttacatgaacagcaggagctttgggcccag
gatctgaacaaagtccgtgagcggatgacaaagttcattgatgacacgatgagagaaact
gccgagcccttcctgtttgtggatgagttcctcacgtacctgttttcccgggagaacagc
atttgggatgagaagtatgacgtggtggatgtgcaggacatgaacaaccccttgtctcat
tactggatctcctcatcacataacacgtacctcacgggtgaccagcttcggagcgagtcg
tccccggaggcctatatccgctgtctgcggatgggctgccgctgcattgagctggactgc
tgggacgggcccgacgggaagcccatcatctaccacggctggacgcggaccaccaagatc
aagtttgatgacgtcgtgcaggccatcaaggaccatgcctttgtcacctcgagcttcccc
gtgatcctgtccatcgaggagcactgctgcctgcagcagcagcgccacatggccagggtg
ttcaaggaggcgttcggcgacctgctgctgaccaagcccacggaggccagtgccgaccag
ctgccgtcgcccagccagctgcgggagaagatcatcatcaagcataagaagctgggcccc
cgaggcgacgtggatgtcaacgtggaggacaagaaagatgaacacaggcagcagggtgaa
ctgtacatgtgggattccatcgaccagcgatggactcggcactactgcgccattgctgac
gccaagctgtccttcagcgacgacattgaacagactacggaaggtgaacagcccccggat
atagcccccacggagctgcattttggggagaagtggttccacaagaaggtggagaagagg
acaagcgccgagaagctgctgcaggaatactgcgccgagacggggggcaaggatgggacc
ttcttggtgcgggagagcgagacgtaccccaatgactacaccctgtccttctggcggtcg
ggccgcgtccagcactgccggatccgctccaccatggagggcgggaccctgaagtattac
ctgactgacaacctcatgttcaccagcatctatgccctcatccagcactacagcgagacg
cacctgcgctgtgccgagttcgagctccggctcaccgacccagttcccaaccccagcccg
cacgagtcgaagccgtggtactatgacgggctgagccgcggagaagcggaggacatgctg
atgagggttccccgggatggggccttcctgatccggaagcgggaaggttctgactcctac
gccatcaccttcagggccaggggcaaggtgaagcactgtcgcatcaaccgggacggccgg
cacttcgtgctgggcacctccgcctacttcgagagcctcgtggagctggtcagctactac
gagaagcacgcactctaccggaagatgaaactgcgctaccccgtgacccccgagctcctg
gagcgctacaatatggaaagagatataaactccctctatgatgtcagcaggatgtatgtg
gatcccagtgaaatcagcccttccatgcctcagagaaccgtgaaagctctgtatgactac
aaagccaagcgaaacgatgagctgagcttctgccgtggcgccctcatccacaatgtctcc
aaggagcctgggggctggtggaaaggagactacggaaccagaatccagcagtacttcccg
tccaattacgttgaagacatttcaacagctgacggggaggacctggaaaagcagattatt
gaagacaatcccttagggtctctttgcagaggaatactggatctcaacacctataatgtt
gtaaaggccccacaggggaagaaccagaagcctttcgtctttatcttggagcccaagaag
cagggtgaccctccggtggagtttgccacagacaaggtggaggagctgtttgagtggttc
cagagcatccgggagatcacctggaagatcgacaccaaggagaacaacatgaagtactgg
gagaagaaccagtccatcgccatcgagctctcggacctggtcgtctactgcaaaccaacc
agcaagaccaaggacaacctagaaaaccccgacttccgagaaatccgctccttcgtggag
acaaaggctgacagcatcgtcagacagaaacccaacgatctcttgaaatacaatcaaaag
ggcctgacccgcgtttaccccaagggacagcgggtggactcctccaactacgaccccttc
cgcctctggctgtgtggctcccagatggtggcactcaatttccagacaccagataagtac
ctgcagatgaatcacgccctgttttccctcaatgggcggactggctacgtcctgcagccc
gagagcatgagggcggagaagtacgaccccatgccgcccgagtcccagaggaagatcctg
atgactctgacggtcaaggttctgggggctcgtcatctccccaaacctggacgaagtatt
gcatgtccctttgtggaggtggaaatatgcggagccgaatatgacaacaacaagttcaaa
acaacagttgtgaatgacaacggcctaagccctgtttgggctccgacacaggagaaggtg
acatttgaaatttatgacccaaacctcgcgtttctacgctttgtggtttacgaggaagat
atgttcagcgatcccaactttctcgcgcatgccactttccccattaaaggaatcaaatca
ggatttagatctgttcctctgaagaacggctacagtgaagacatggagctggcttccctc
ctggttttctgtgagatgcggccagtcctggagagcgaagaggagctttactcctcctgc
cgccagctgcggaggcggcaagaagaactgaacaaccagctctttctgtacgacacacac
cagaacttgcgcagcgccaaccgggatgccctggtcagagagttcaacgtcaacgagaac
cagctgcagctgtaccaggagaagtgcaaccgcaggttaagagagaagagagtcagcaac
agcaagttctactcatag
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integrated database retrieval system
