Delphinapterus leucas (beluga whale): 111181452
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Entry
111181452 CDS
T05885
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle04022
cGMP-PKG signaling pathway
dle04024
cAMP signaling pathway
dle04062
Chemokine signaling pathway
dle04071
Sphingolipid signaling pathway
dle04270
Vascular smooth muscle contraction
dle04350
TGF-beta signaling pathway
dle04360
Axon guidance
dle04510
Focal adhesion
dle04520
Adherens junction
dle04530
Tight junction
dle04611
Platelet activation
dle04670
Leukocyte transendothelial migration
dle04810
Regulation of actin cytoskeleton
dle04921
Oxytocin signaling pathway
dle05135
Yersinia infection
dle05163
Human cytomegalovirus infection
dle05200
Pathways in cancer
dle05205
Proteoglycans in cancer
dle05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
111181452 (ROCK1)
04071 Sphingolipid signaling pathway
111181452 (ROCK1)
04024 cAMP signaling pathway
111181452 (ROCK1)
04022 cGMP-PKG signaling pathway
111181452 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
111181452 (ROCK1)
04520 Adherens junction
111181452 (ROCK1)
04530 Tight junction
111181452 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
111181452 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
111181452 (ROCK1)
04670 Leukocyte transendothelial migration
111181452 (ROCK1)
04062 Chemokine signaling pathway
111181452 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
111181452 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
111181452 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
111181452 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111181452 (ROCK1)
05206 MicroRNAs in cancer
111181452 (ROCK1)
05205 Proteoglycans in cancer
111181452 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
111181452 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
111181452 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dle01001
]
111181452 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
dle03036
]
111181452 (ROCK1)
Enzymes [BR:
dle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
111181452 (ROCK1)
Protein kinases [BR:
dle01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
111181452 (ROCK1)
Chromosome and associated proteins [BR:
dle03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
111181452 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Cortex-I_coil
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
111181452
NCBI-ProteinID:
XP_022442506
UniProt:
A0A2Y9PB74
LinkDB
All DBs
Position
Unknown
AA seq
1354 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNENRTSSNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSHLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSITQLESLNRELQERNRILENSKSQMD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRLLLQNELKTHAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENSKKIQELQSEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKEHTVSRLEETNSMLTKDIELLRKENE
ELTDKMKKAEEEYKLKKEEEINNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
NT seq
4065 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcagattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccaccaggaag
gtatatgctatgaagcttctcagcaaatttgaaatgattaagagatccgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaacagtccttgggttgttcagctattt
tatgcattccaagatgatcgttatctctacatggtaatggaatacatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcccgattttatactgca
gaagtagttctggcattggatgcaatccattccatgggttttattcatagagatgtgaag
cctgataacatgctgctggataagtctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttgggacacctgattat
atttcccctgaagtattaaaatctcaaggtggtgatggttattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacaccattttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattcacttaccttccct
gatgataatgacatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattagggcggaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gatcagtgggcttgggaaacactccgagacactgtagcgccagttgtacctgatttaagt
agtgacattgacacaagtaactttgatgacttggaagaagataaaggagatgaagaaaca
ttccctatacctaaagcttttgttggcaatcaactaccctttgtaggatttacatattat
agcaatcgtagatacttatcttcagcaaatcctaatgaaaacagaactagctctaatgtg
gataaaagcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacagttgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaactc
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaacctagaatctaca
gtgtctcagattgagaaggagaaaatgttgctacagcatagaattaatgagtaccaaaga
aaagcagaacaggaaaatgagaagaggaggaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtcagtcagaattcacaccttgctaatgagaagctg
gcacaattacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gctgtaagattaaggaagagtcacaccgagatgagcaaatcaattactcagctagagtcc
ctgaatagagaattgcaggagagaaatagaattttggagaattccaagtcacaaatggac
aaggattattaccagctgcaagctgtattagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagacctacaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataaccttgaaagagtggaaggagaaagaaaagaggctcaagacatgcttaat
cattcagaaaaggaaaagaataacttagaaatagatttaaactacaagcttaaatcatta
cagcaaaggttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcaatctattgaagaggccaagtctgttgcaatgtgtgagatggaaaaaaagctg
aaggaagagagggaagctcgagagaaggctgaaaatagggttgttcagattgagaagcag
tgctccatgctagatgttgatctaaaacaatctcagcagaagctagagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctatccctgcaactggagcaggagtca
aataagcgactgttgttacaaaatgaattgaagacccacgcatttgaggcagacaattta
aaaggtttagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagatta
ttagagtttgaattagctcagcttacaaaacaatacagaggaaatgaaggacagatgcgg
gagctacaagatcagcttgaagctgagcaatatttctcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaaaattcaaagaaaatacaggaa
ctacaaagtgaaaaagaaactcttgctactcagttggatctagcagaaacaaaagccgag
tctgagcagttggctcgagggcttctggaagaacagtattttgaattgacccaagaaagc
aagaaagctgcttcaagaaatagacaagagattacagataaagagcacactgttagtcgg
ctcgaagaaacgaacagtatgctaaccaaagatattgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaagaaggcagaggaagaatataaactgaagaaggaggaggag
atcaataatcttaaggctgcctttgaaaagaatatcaatacagaacgaacccttaaaacg
caggctgttaacaagttggcagaaataatgaatcggaaagactttaaaattgacagaaag
aaagctaatacacaggatttgagaaagaaggaaaaggaaaatcgaaagctacaacttgaa
ctcaaccaggaaagagagaaattcaaccagatggtagtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgagcttcagatgcagttg
gctagcaaagagagtgacattgagcaattgcgtgcgaaacttttggacctatcagattct
acaagtgttgctagttttcctagtgctgatgaaactgatggaaaccttccagaatcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaaagatacggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattttgttttataatgatgaacaagataaggaa
caatccaatccatctatggtattggacattgataaattgtttcatgttcgtcctgtaact
caaggagatgtgtacagagctgaaactgaagaaattcctaaaatattccagatactatac
gcaaatgaaggtgaatgtagaaaagacgtagagatggaaccagtacaacaagctgagaaa
actaattttcaaaaccacaaaggtcatgagttcattcctaccctctaccactttcccgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccaccccctgccctggaa
tgtcgaaggtgccacgttaagtgccacagagatcacttagataagaaagaggacttaatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgctactagcatgt
tctcaggatgaacaaaaaaaatgggtaactcatttagtaaagaagattcctaagaatcca
ccatctggttttgttcgtgcgtcgcctcgaacactttctacaagatccactgcaaatcag
tctttccggaaagtggtcaaaaatacatctggaaaaactagttaa
DBGET
integrated database retrieval system