KEGG   Delphinapterus leucas (beluga whale): 111183639
Entry
111183639         CDS       T05885                                 
Symbol
APC
Name
(RefSeq) adenomatous polyposis coli protein isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle04310  Wnt signaling pathway
dle04390  Hippo signaling pathway
dle04550  Signaling pathways regulating pluripotency of stem cells
dle04810  Regulation of actin cytoskeleton
dle04934  Cushing syndrome
dle05010  Alzheimer disease
dle05022  Pathways of neurodegeneration - multiple diseases
dle05165  Human papillomavirus infection
dle05200  Pathways in cancer
dle05206  MicroRNAs in cancer
dle05210  Colorectal cancer
dle05213  Endometrial cancer
dle05217  Basal cell carcinoma
dle05224  Breast cancer
dle05225  Hepatocellular carcinoma
dle05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    111183639 (APC)
   04390 Hippo signaling pathway
    111183639 (APC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    111183639 (APC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    111183639 (APC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111183639 (APC)
   05206 MicroRNAs in cancer
    111183639 (APC)
  09162 Cancer: specific types
   05210 Colorectal cancer
    111183639 (APC)
   05225 Hepatocellular carcinoma
    111183639 (APC)
   05226 Gastric cancer
    111183639 (APC)
   05217 Basal cell carcinoma
    111183639 (APC)
   05213 Endometrial cancer
    111183639 (APC)
   05224 Breast cancer
    111183639 (APC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    111183639 (APC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    111183639 (APC)
   05022 Pathways of neurodegeneration - multiple diseases
    111183639 (APC)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    111183639 (APC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:dle01009]
    111183639 (APC)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:dle03036]
    111183639 (APC)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:dle04812]
    111183639 (APC)
Protein phosphatases and associated proteins [BR:dle01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     111183639 (APC)
Chromosome and associated proteins [BR:dle03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    111183639 (APC)
Cytoskeleton proteins [BR:dle04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     111183639 (APC)
SSDB
Motif
Pfam: Arm_APC_u3 APC_basic EB1_binding APC_r APC_u5 APC_u14 APC_rep APC_u15 APC_u9 APC_N_CC SAMP Arm APC_u13 APC_15aa Suppressor_APC ARM_ARMC5 ZER1-like_2nd Sec7-like_HUS
Other DBs
NCBI-GeneID: 111183639
NCBI-ProteinID: XP_022446871
UniProt: A0A2Y9PNP0
LinkDB
Position
Unknown
AA seq 2864 aa
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR
RGFVNGSRENTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRITRIQQIEKDILRIRQLLQSQAT
EAERSSQSKHEAGSHEAERQNESQGVAEINMATSGSGQGSTARIDHETASVLSSSSTHSA
PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL
HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC
WEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGRKATRGISSQ
ELGQGLSGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSM
KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE
STLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNV
SSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMG
AVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEA
ELDAQHLSETFDNIDNLSPKASHRSKQRHKQNLYGDYVFDTNRHDDNRSDNFNTGNMTVL
SPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGISLVNYHPATENPGTSSKRGLQIST
TAAQIAKVMEEVSAIHTSQEDRSSGSTPELHCGTDERNALRRSSTTHTHANSYNFTKSEN
SNRTCPVPYAKVEYKRSSNDSLNSVSSSDGYGKRGQMKPVESYSEDEESKFCSYGQYPAD
LAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQN
EERQSRSQSTTYPVYPESTDDKHLKFQPHFGQQECVSPYRSRAANGSETNRVGSNHGINQ
NVNQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKHHVDQPIDYSLKY
TTDIPSSQKPAFSFSKNSSGQSTKTEHISSSSENTATPSSNAKRQNQLHHSSAQSRSGQT
QKATSSSCKVPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCDQTTQEADSANT
LQIAEIKESSGTRSTEDSVSEVPTVSQHIRTKSSRLQASGLSSESTRHKAVEFSSGAKSP
SKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPS
DLPDSPGQTMPPSRSKTPPPPPPQSAQTKQEVPKNKAPSAEKRESGPKQAAVNAAVQRVQ
VLPDADALLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETENE
QPEESNESQGKEAEKPTDSEKDLLDDSDDDDIEILEECIISAMPTRSSRKAKKPAQTSSK
LPPPVARKPSQLPVYKLLPSQNRLQAQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDL
TIESPPNELAAGEGVRAGTQSGEFEKRDTIPTEGRSTDEAQTGKASSVTVPELDDNKTEE
GDILAECINSAMPKGKSHKPFRVKKIMDQVQQASMSSSGTNKNQLDGKKKKPTSPVKPIP
QNTEYRTCVRKNTDSKNNLNAERNFSDNKDSKKQNLKNNSKDFNDKVPNNEDRVRGSFTF
DSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKESKESEAKVTSHTEL
TSNQQSANKTQAVPKHPINRGQPKPVLQKQSTFPQPSKDIPDRGAATDEKLQNFAIENTP
VCFSRNSSLSSLSDIDQENNNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPV
CFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKADNEKHSPRNMGGTLAEDLTLN
LKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLK
SGISLGSPFHLTPDQEEKPFASNKGPRILKPGEKSTLEAKKLESENKGIKGGKKVYKSLI
TGKIRSNSEVSSQMKQPLQTNMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASK
SPSEGQAATTSPRGAKPSVKSELSPVTRQASQTPGSNKGPSRSGSRDSTPSRPAQQPLSR
PMQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLT
KQTGLSKNVSSIPRSESASKGLSQMSTSNGSNKKVELSRMSSTKSSGSESDRSERPVLVR
QSTFIKEAPSPTLRRKLEESASFESLSPSSRPDSPSRSQAQTPILSPSLPDMSLSTHSSV
QAGGWRKLPPNLSPTIEYNDGRPVKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLP
RVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSTSGTKQTKENQVSTKGTWRKMKESE
ISPTNSTSQTTSSGAANGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNT
PPVIDTVSEKGNPNTKDSKDNQGKQNVSNGSAPVRTMGLENRLNSFIQVDAPDQKGTEGK
PGQSHPVAASETNESSIAERTPFSSSSSSKHSSPSGTVAARVSPFNYNPSPRKSSADSTS
ARPSQIPTPVNNNTKKRDSKSDNTESSGTQSPKRHSGSYLVTSV
NT seq 8595 nt   +upstreamnt  +downstreamnt
atggctgcagcttcatatgatcagttgttaaagcaagttgaggcactgaagatggagaac
tcaaatcttcgacaagagctagaagataattccaatcatcttacaaaactggaaactgag
gcatctaatatgaaggaagtacttaaacaactacaaggaagtattgaagatgaagctatg
gcttcgtctggacagattgatttattagagcgtctcaaagaacttaacttagatagcagt
aattttcctggagtgaaactacggtcaaaaatgtccctccgttcttacggaagccgagaa
ggatctgtatctagtcgttcaggagagtgcagtcctgttcctatgggttcatttccgaga
agagggtttgtaaatggaagcagagaaaataccggttatttagaagaacttgaaaaagag
agatcattgcttcttgctgaccttgacaaagaagaaaaggaaaaagactggtattatgct
caacttcagaatctcactaaaagaatagatagtcttcctttaactgaaaatttttcctta
cagacagatatgaccagaaggcagttggaatatgaagcaaggcaaatcagagttgcaatg
gaagaacaactgggtacttgccaggatatggaaaaacgagcacagcgaagaataaccaga
attcaacaaatagagaaggacatacttcgtatacgacagcttttacagtcccaagcaaca
gaagcagagaggtcatctcagagcaagcatgaagccggctcacatgaagctgagcgacag
aatgaaagtcaaggagtggcagaaatcaacatggcaacttcgggtagtggtcagggttca
actgcacgaatagatcacgaaacagccagtgttttgagttctagcagcacacattctgct
cctcgaaggctgacaagtcatctgggaaccaaggtggaaatggtgtattcattgttgtca
atgcttggtactcatgataaggatgatatgtcgcgaactttgctagctatgtctagctcc
caagacagctgtatatccatgcgacagtctggatgtcttcctctcctcatccagctttta
catggcaatgacaaagactctgtgttgttgggaaattcccggggcagtaaagaggctcgg
gccagggccagtgcagcactccacaacatcattcactcacagcctgatgacaagagaggc
aggcgtgaaatccgagtccttcatcttttggaacagatacgagcttactgtgaaacctgt
tgggagtggcaggaagcccatgaacaaggcatggaccaggacaaaaatccaatgccagct
cctgttgaacatcaaatctgtcctgctgtgtgtgttctaatgaaactttcgtttgatgag
gagcatagacacgcgatgaatgaacttggtaggaaggctacccggggcatttcatcacag
gagctagggcaggggctttcagggggactacaggccattgcagaattattgcaagtggac
tgtgaaatgtatggacttactaatgaccactacagtattaccttaagacgatatgcagga
atggctttgacaaacttgactttcggagatgtagccaacaaggctacactatgctctatg
aaaggctgcatgagagcacttgtggcccaactaaaatctgaaagtgaggacttacagcag
gttattgcaagtgttttgaggaatctgtcttggagagcagatgtaaatagtaaaaagact
ttgcgtgaagttggaagtgtgaaagcattgatggaatgtgctttggaagtgaaaaaggaa
tcaaccctcaaaagcgtattgagtgccttatggaatttgtcagcacactgcactgagaat
aaagctgatatatgtgccgtagatggtgcgcttgcatttttggttggcactctcacttac
cggagccagacaaatactttagctattattgaaagtggaggtgggatattacggaatgtg
tccagcttgatagctacgaatgaggaccacaggcaaatcctaagagagaataattgctta
caaaccttattacaacacttgaaatctcacagtttgacaatagtcagtaatgcatgcgga
accttgtggaatctctcagcaagaaatcctaaagatcaggaagcattatgggacatggga
gcagtcagcatgctcaagaacctcattcattcaaagcacaagatgattgctatgggaagt
gctgcagctttaaggaatctcatggcaaatagacctgcaaagtataaggatgccaatatc
atgtctcctggttcaagcttgccttctcttcatgtcaggaaacaaaaagccctagaagca
gaattagatgctcagcatttatcagaaacttttgacaatattgacaatttaagtcccaag
gcatctcatcgtagtaagcagagacacaagcaaaatctctatggtgactatgtttttgac
accaatcgacatgatgataataggtcagacaattttaatactggaaacatgactgtcttg
tcaccatatttaaatactacagtgttgcccagctcctcttcatcaaggggaagtttagat
agttctcgttctgagaaagatagaagtttggagagagaacgaggtattagcctagtcaac
taccacccagcaacagaaaatccaggaacctcttcgaagcgaggtttgcagatttctacc
actgcagcccagattgccaaagtcatggaagaagtatcagccattcatacctcccaggaa
gacagaagttctgggtctaccccggaactacattgtggaacagatgagaggaatgcacta
agaagaagctctaccacccacacacatgcaaactcttacaacttcaccaagtcagaaaac
tcaaacaggacatgtccagtgccatatgccaaagtagaatacaagagatcttcaaatgat
agtttaaatagtgtcagcagtagtgatggttatggtaaaagaggtcaaatgaaaccagtt
gaatcctattctgaagatgaggaaagtaaattttgcagctatggtcagtatccagctgac
ctagcccataaaatacatagtgcaaatcatatggatgataatgatggagaactagataca
ccaataaattatagtcttaaatattctgatgaacagttgaactccggaaggcaaagtcct
tcacagaatgaaaggtgggcaagacccaaacatataatagaagatgaaataaaacaaaat
gaggaaagacaatcaaggagtcaaagcacaacttatcctgtatatcctgagagcactgat
gataaacacctcaagttccaaccacattttggacagcaagaatgtgtttccccatatagg
tcaagagcagccaatggttcagaaacaaatcgagtaggttctaatcatggaattaatcaa
aatgtaaatcagtctttgtgtcaggaagatgactatgaagatgataagccaaccaactat
agtgaacgttactctgaggaagagcaacatgaggaagaagagagaccaaccaattatagc
ataaaatataatgaagaaaaacatcatgtggatcagcctattgattatagtttaaaatat
accacagacattccttcttcacagaaaccagcattttcattctcaaagaattcatctgga
cagagcactaaaactgaacacatctcttcaagcagtgagaatacagccacaccttcatct
aatgccaagaggcagaatcaactccatcacagttcagcacagagcaggagtggtcagacc
caaaaagccacctcttcctcttgcaaagttccctctatcaaccaagaaacaatacagact
tactgtgtagaagataccccaatatgtttttcaagatgtagttcattatcatctttgtca
tcagctgaagatgaaatagggtgtgatcagacaacacaagaagcagattctgctaatacc
ctacaaatagcagaaataaaagaaagcagtggaactagatcaactgaagattctgtgagt
gaagttccaacagtgtcacagcacattagaaccaaatccagcagactccaggcttctggt
ttatcttcagaatcaaccaggcacaaagctgttgaattttcttcaggggccaaatctcca
tcaaagagtggtgctcagacacctaaaagtccaccagagcactacgttcaggagactcca
ctcatgtttagcaggtgtacttctgtcagttcacttgatagttttgagagtcgttcaatt
gccagctccgttcagagtgaaccctgcagtggaatggtgagtggcattataagccccagt
gaccttccagatagccctggacaaaccatgccgccaagcagaagtaaaacccctcctccc
cctcctcctcagtcagctcagactaagcaagaagtacctaaaaataaagcacctagtgct
gagaagagagaaagtggccctaagcaagctgctgtaaatgctgcagtacagagggtccag
gttcttccagatgctgatgctttgttacattttgccacagaaagtactcctgatggattt
tcttgttcatctagcctgagtgctctgagcctcgatgagccatttattcagaaagatgtg
gaattaagaataatgcctccggttcaggaaaatgacaatgggaatgaaacagaaaatgag
cagcctgaagaatcaaatgaaagccagggaaaagaggcggaaaaacccaccgattctgaa
aaagatctgttagatgattcagatgatgatgatattgaaatactagaagagtgtattatt
tctgccatgccaacaagatcttcacgcaaagccaaaaagccagcccagacgtcttccaaa
ttacctccacctgtggcaaggaaaccaagtcagctgcctgtgtacaaacttctgccatca
caaaacagattacaagcacaaaagcatgttagttttacaccaggagatgatatgcctcgg
gtgtattgtgtagaagggacacctataaacttttccacagctacatctctaagtgatcta
acgatagaatcccctccaaatgagttagctgctggagaaggtgttagagcaggaacacag
tcaggtgaatttgaaaaacgagacaccattcctacagaaggcagaagtacagatgaggct
caaacagggaaagcctcatctgtaactgtacctgaactggatgacaataaaacagaagaa
ggcgatattcttgcagaatgcattaattctgctatgcccaaaggaaaaagtcacaagcct
ttccgtgtgaaaaagataatggaccaggtccaacaagcatctatgtcttcatctggaact
aacaaaaatcaattagatggtaagaagaagaaacctacttcaccagtaaaacctatacca
caaaatactgaatacaggacatgtgtaaggaaaaatacagactcaaaaaataatttaaat
gctgaaagaaatttctcagacaacaaagattcaaagaaacagaacttgaaaaataattcc
aaggacttcaatgataaggtcccaaataatgaagatcgagtcagaggaagttttactttt
gattcacctcatcattacacacctattgaaggcactccatactgtttttcacgaaatgat
tctttgagttctctagattttgatgatgatgatgtggacctttccagggaaaaggctgaa
ttaagaaaggggaaggaaagtaaggaatcagaagctaaagttaccagccacacagaacta
acctcaaaccaacaatcagctaataagacacaagctgttccaaaacatccaataaatcga
ggtcagcctaaacccgtgctgcagaagcaatccacttttccccagccctccaaagatata
ccagacagaggggcagcaacagacgagaaattacagaattttgctattgaaaacactccg
gtttgcttttcccgaaattcctctctaagttctcttagtgacattgatcaagaaaacaac
aacaacaaggaaaatgaacctatcaaagagacagagccccctgactcacagggagaacca
agtaaacctcaggcgtcaggttatgctcctaaatcatttcacgttgaagatacccctgtt
tgtttctcaagaaacagttctctcagttctctcagtattgattctgaagatgacctgttg
caggaatgtataagttctgcaatgccaaaaaagaaaaagccttcaagactcaaggctgat
aatgaaaagcatagtcccagaaatatgggtggcacattagcagaagatttgacactcaat
ttgaaagatatacagagaccagattcagaacatggtttatcccctgattcagaaaatttc
gattggaaagctattcaggaaggtgcaaattccatagtaagtagtttacatcaagctgct
gctgccgcatgtttatctagacaagcttcgtctgattcagattccatcctttccctgaaa
tcaggaatctctctgggatcaccatttcatcttacacctgatcaagaggaaaaacccttt
gcaagtaataaaggcccacgaattctaaaacctggggagaaaagtacattggaagctaag
aagttagaatctgaaaataaaggaataaaaggagggaaaaaagtttataaaagtttgatt
actggaaaaattcgatctaattcggaagtttcaagccaaatgaaacaaccccttcaaaca
aacatgccttcaatctctcgaggtaggacaatgattcatattccaggagttcggaatagc
tcttcaagtacaagtccggtttctaaaaaaggcccaccccttaagactccagcctccaaa
agccctagtgaaggtcaggcagctaccacttcccccagaggagccaagccatcagtgaag
tcagaattaagccctgttacgaggcaggcgtcccagacacctgggtcaaataaagggcct
tctagatcaggatctagagattccactccttcaagacctgcccagcagccattaagtaga
cctatgcagtctccagggcgaaactcaatttctcctggtagaaatggaataagtcctccc
aacaaattatctcaactgccaaggacgtcatcccctagtactgcttcaactaagtcctcg
ggttctgggaaaatgtcttacacatctcctggcagacagatgagccaacagaacctcacc
aaacaaacgggtttatccaagaatgtcagtagtatcccaagaagtgaatctgcctccaaa
ggactaagtcaaatgagtactagcaatggatccaataaaaaggtagaactttctagaatg
tcttcaactaaatcaagtggaagtgaatctgataggtcagagagacctgtattagtacgc
cagtcaactttcatcaaagaagctccaagcccaaccctaaggagaaaattggaggaatcc
gcttcatttgaatctctttctccatcttctagaccagattctcccagtaggtcccaggca
cagactccaattttaagtccttcccttcctgatatgtcgctgtctacacattcatctgtt
caggctggtggatggcgaaaactcccacctaatctcagtcccaccatagagtataatgat
ggaagaccagtaaagcgccatgatatagcacgctctcattctgaaagtccttccagactt
cccatcaataggtcaggaacctggaaacgtgagcacagcaaacactcatcatcccttcct
cgagtaagcacttggaggagaactggaagttcatcctcaattctttctgcttcatcagaa
tctagtgaaaaagcaaaaagtgaggatgaaaaacatgtgaactctacttcaggaaccaaa
caaactaaagaaaaccaagtatccacaaaaggaacatggagaaaaatgaaagaaagtgaa
atttctcccaccaatagtacttctcagaccacttcctcaggtgctgcaaatggtgctgaa
tcaaagactctgatttatcaaatggcacctgctgtttctaaaacagaggatgtttgggtg
agaattgaggactgccccattaacaaccctagatctggaagatctccaacaggaaatact
cccccagtgattgacactgtttcagaaaagggaaacccaaacactaaagattcaaaagat
aatcaggggaaacaaaatgtgagcaatggtagtgctcctgtacgcaccatgggtttggaa
aaccgcctgaactcctttattcaggtagacgccccagaccaaaaaggaactgagggaaaa
ccgggacaaagtcatcctgtcgctgcatcagagactaatgaaagttctatagctgaacgt
accccatttagttctagcagctcaagcaagcacagttcaccgagtgggactgttgctgcc
agagtgagtccttttaattacaacccaagcccaaggaaaagcagcgcagatagcacttca
gcccgaccatctcagatcccaacgccagtgaataacaacacaaagaaacgagattcaaaa
agtgacaatacagaatccagtggaactcaaagtcctaaacgccattctgggtcttacctt
gtgacatctgtttaa

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