Delphinapterus leucas (beluga whale): 111187347
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Entry
111187347 CDS
T05885
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle01521
EGFR tyrosine kinase inhibitor resistance
dle01522
Endocrine resistance
dle04010
MAPK signaling pathway
dle04014
Ras signaling pathway
dle04015
Rap1 signaling pathway
dle04066
HIF-1 signaling pathway
dle04068
FoxO signaling pathway
dle04081
Hormone signaling
dle04114
Oocyte meiosis
dle04140
Autophagy - animal
dle04144
Endocytosis
dle04150
mTOR signaling pathway
dle04151
PI3K-Akt signaling pathway
dle04152
AMPK signaling pathway
dle04211
Longevity regulating pathway
dle04213
Longevity regulating pathway - multiple species
dle04510
Focal adhesion
dle04520
Adherens junction
dle04550
Signaling pathways regulating pluripotency of stem cells
dle04730
Long-term depression
dle04913
Ovarian steroidogenesis
dle04914
Progesterone-mediated oocyte maturation
dle05200
Pathways in cancer
dle05202
Transcriptional misregulation in cancer
dle05205
Proteoglycans in cancer
dle05214
Glioma
dle05215
Prostate cancer
dle05218
Melanoma
dle05224
Breast cancer
dle05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111187347 (IGF1R)
04014 Ras signaling pathway
111187347 (IGF1R)
04015 Rap1 signaling pathway
111187347 (IGF1R)
04066 HIF-1 signaling pathway
111187347 (IGF1R)
04068 FoxO signaling pathway
111187347 (IGF1R)
04151 PI3K-Akt signaling pathway
111187347 (IGF1R)
04152 AMPK signaling pathway
111187347 (IGF1R)
04150 mTOR signaling pathway
111187347 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
111187347 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
111187347 (IGF1R)
04140 Autophagy - animal
111187347 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
111187347 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
111187347 (IGF1R)
04520 Adherens junction
111187347 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
111187347 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
111187347 (IGF1R)
04914 Progesterone-mediated oocyte maturation
111187347 (IGF1R)
09156 Nervous system
04730 Long-term depression
111187347 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
111187347 (IGF1R)
04213 Longevity regulating pathway - multiple species
111187347 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111187347 (IGF1R)
05202 Transcriptional misregulation in cancer
111187347 (IGF1R)
05205 Proteoglycans in cancer
111187347 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
111187347 (IGF1R)
05214 Glioma
111187347 (IGF1R)
05218 Melanoma
111187347 (IGF1R)
05215 Prostate cancer
111187347 (IGF1R)
05224 Breast cancer
111187347 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111187347 (IGF1R)
01522 Endocrine resistance
111187347 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dle01001
]
111187347 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
dle04090
]
111187347 (IGF1R)
Enzymes [BR:
dle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
111187347 (IGF1R)
Protein kinases [BR:
dle01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
111187347 (IGF1R)
CD molecules [BR:
dle04090
]
Proteins
111187347 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
111187347
NCBI-ProteinID:
XP_022454621
UniProt:
A0A2Y9QAK7
LinkDB
All DBs
Position
Unknown
AA seq
1368 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENHECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEIVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDILHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKADKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNAIFVPRPERKRREVMQVANTTMSSRNRNTTVVDTYNITDPEELETEYPFFE
SRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLIIALPIAVLLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAAR
NCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFG
VVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF
LEIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDR
HSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKKERALPLPQSSTC
NT seq
4107 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggccaggcatcgacatccgc
aacgactaccagcagctgaagcggctggagaactgcacggtgatcgagggctacctccac
atcctgctcatttccaaggctgaggactaccgcagctaccgcttccccaagctcacggtc
atcactgagtacctgctgctgttccgcgtggccggcctcgagagcctcggcgacctcttc
cccaacctcacagtcatccgtggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggatattgggctctacaacctgcgaaacattacccgtggggcc
atccggatcgagaagaatgctgacctctgctacctctccacggtggactggtccctaatc
ctggatgccgtgtccaataactacatcgtgggaaataagcccccaaaggagtgtggggac
ctgtgcccggggacgatggaggagaagccgctgtgcgagaagacgaccatcaacaacgag
tacaactaccgctgctggaccacgaaccgctgtcagaaaatgtgcccgagcacgtgcggg
aagcgggcgtgcacggagaaccacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcccgacaacgacacggcctgcgtggcctgccgccactactactatgccggtgtctgt
gtgcccagctgcccgcccaacacctaccgcttcgagggctggcgttgtgtggaccgtgac
ttctgcgccaacatccccaacgctgagagcagcgattccgagggcttcgtgatccacgac
ggcgagtgcatgcaggagtgcccgtcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgcgaaggcccttgtcccaaagtgtgtgaggaagagaaaaagacaaagacc
attgattctgtcacttctgctcagatgctccaaggatgcaccattttcaagggcaatcta
ctcattaatatccggcgcggcaacaacatcgcttcggaactggagaacttcatgggactc
atcgagatcgtgacgggctacgtgaagatccgccactcccatgccttggtctccttgtcc
ttcctgaagaaccttcgccagatcctaggagaggagcaactagaggggaattactccttc
tacgtcctcgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaagccgggaaaatgtactttgctttcaatcccaaattgtgtgtctctgagatttac
cgcatggaggaagtgacggggactaaagggcgccagagcaaaggggacataaacaccagg
aacaacggagagagagcctcctgtgaaagtgacatcctgcacttcacctccaccaccacg
tggaagaaccgcatcatcatcacctggcaccggtaccggccccctgactacagggacctc
atcagcttcaccgtctactacaaggaagcaccctttaaaaacgtcacagagtatgacggg
caggatgcctgtggctccaacagctggaacatggtagatgtggacctcccacccaacaag
gacgtggagcccggcattttactgcatggactgaagccctggacacagtatgccgtttac
gtcaaggctgtgaccctcaccatggtggagaatgaccacatccgtggagccaagagcgag
atcttgtacattcgcaccaatgcttcagttccttccatccccctggatgtactctcagca
tcaaactcctcttctcagctgatcgtgaagtggaaccctccttccctgcccaacggcaac
ctgagctactacatcgtaaggtggcagcgccagccccaggacagctacctttaccggcac
aattactgctccaaagcagacaaaatccccatcaggaagtacgccgatggcaccatcgac
gttgaggaggtgacggagaatcccaagaccgaagtgtgtggtggggagaaagggccgtgc
tgcgcttgccccaaaaccgaagccgagaagcaggccgagaaggaggaggccgagtaccgc
aaggtcttcgagaatttcctgcacaacgccatcttcgtgcccagacctgaacggaagcgg
agggaggtcatgcaggtcgccaacaccaccatgtccagccggaacaggaacaccacggtg
gtggacacctacaacatcacagacccagaggagctcgagaccgagtaccctttcttcgag
agcagagtggataacaaggagagaactgtcatctccaacctccggccttttactctgtac
cgaatcgatatccacagctgtaaccacgaagctgagaagcttggctgcagcgcctccaac
tttgtctttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccagtgacc
tgggagccaaggcctgagaactccatctttttaaaatggccagaacctgagaatcccaat
ggattgattttaatgtatgaaataaaatatggatcacaagtcgaggatcagcgggaatgt
gtgtccagacaggagtacaggaagtatggaggggccaagctaaaccggctcaacccgggg
aactacacggcccggatccaggccacctctctctctgggaacgggtcatggactgatcct
gtgttcttctatgtccaggccaaaacaacgtatgaaaacttcatccatctgatcattgct
ctgcccattgccgttctgctgatagtaggagggttggttataatgctgtacgtcttccat
agaaaaagaaataacagcaggctggggaacggagtgctgtatgcctctgtgaacccggag
tacttcagtgcagccgatgtgtacgtgcctgacgagtgggaggtcgcccgggagaagatc
accatgagccgggagctggggcagggctcgttcgggatggtttatgaaggtgtcgccaag
ggcgtggtcaaggatgagcctgagaccagggtggccattaagacggtgaacgaagccgcc
agcatgcgcgagaggattgagtttctcaacgaggcctcggtgatgaaggagttcaactgt
caccatgtggtgcgcttgctgggcgtggtgtcccagggccagccgacgctggtcatcatg
gaactgatgacccggggggacctcaaaagttatctccggtctctgaggccagaaatggag
aataatccagtcctagcacctcccagcctaagcaaaatgatccagatggctggagagatt
gcagatggcatggcatacctcaacgccaataagtttgtccacagagacctcgctgcccgg
aactgcatggtggccgaagatttcacagtcaaaatcggagattttgggatgacgagagac
atctatgagaccgactattaccggaagggagggaaggggctgctgcccgtgcgctggatg
tcccccgagtccctcaaggatggagtcttcaccacgcactctgacgtctggtccttcggg
gtcgtcctctgggagatcgccacgctggccgagcagccataccagggcctgtccaatgag
caagtccttcgctttgtcatggagggcggccttctggacaagccggacaactgtcctgac
atgctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttc
ctggaaatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttc
tactacagcgaggagaacaagccacctgagccagaggagctggacctagagccggagaac
atggagagtgtccccttggacccctcggcatcctcgtcctccctgccactgcccgacaga
cactcaggacacaaggccgagaacggtccgggccctggcgtgctggtccttcgagccagc
ttcgacgagagacagccttatgcgcacatgaacgggggccgcaagaaggagcgggccttg
cctctgccccagtcctcaacctgctga
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integrated database retrieval system
