KEGG   Dehalococcoides mccartyi DCMB5: dcmb_1276
Entry
dcmb_1276         CDS       T02476                                 
Symbol
purH
Name
(GenBank) IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
dmd  Dehalococcoides mccartyi DCMB5
Pathway
dmd00230  Purine metabolism
dmd00670  One carbon pool by folate
dmd01100  Metabolic pathways
dmd01110  Biosynthesis of secondary metabolites
Module
dmd_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:dmd00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    dcmb_1276 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    dcmb_1276 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dmd04147]
    dcmb_1276 (purH)
Enzymes [BR:dmd01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     dcmb_1276 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     dcmb_1276 (purH)
Exosome [BR:dmd04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   dcmb_1276 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS DUF4562
Other DBs
NCBI-ProteinID: AGG06874
LinkDB
Position
1211521..1213062
AA seq 513 aa
MRAILSVSDKTGLIEFARGLSELGFDIYSTGGTKKSLQQANVTVHSISDMTDSPEILDGR
VKTLHPKVHGGILARRDLPEHMAELEKYNIQPIDMVVVNLYPFVKTVSRPDVSLTDALEN
IDIGGPTMIRASAKNFPSVTVVVDPQDYPHVLEHLKTGTLSLDERKKLAQKAFQHVAMYD
TAISQYLWQGEEGFPENMTIALSKRYDLRYGENPHQPAVFYAENRVGHGQNTGITWAQQA
WGKQLSFNNILDADAAWGAATDFSAATVAIVKHTNTCGLCSREDVAEAYKRAFSGDPVSA
YGGIVASNRKVTLSMAEAMKGTFYEIIIAPEYEPEALEFLKTRKDLRILIAELPKHNEAE
TRSLDYRRVKGGLLVQAADELAENAVQTKVVTKREPTPEEMSDLKFAWRAVKHIKSNAIV
LAKNNVLLGMGAGQPNRVVSVDIAKSKAGEASKGSVMASDAMFPFPDSVEQAAAAGVTAI
IQPGGSIRDQESIDAANKHNIAMVFTGTRHFRH
NT seq 1542 nt   +upstreamnt  +downstreamnt
atgagggctatcctaagcgtctcagataaaaccggtcttatcgaattcgccagaggcttg
tcagaactgggttttgatatatacagcaccggcggaaccaagaaatcactccagcaggca
aatgtaactgttcacagtatttcagacatgaccgattcacccgaaatactggacggacgg
gttaaaaccctgcaccccaaggtacacggtggcatactggcccggcgtgacctgcccgaa
catatggccgaactggaaaaatacaatatccaacccattgacatggtggtagtcaatctc
tatccctttgtcaagactgtgtcgcgtccggatgtcagcctgaccgatgcactggagaat
attgatattggcggtccgaccatgatacgggcttctgccaaaaacttccctagcgtgaca
gtggtggtagacccccaggattacccccatgttctggaacacctcaagaccggcactttg
agcctagatgaacgcaagaagctggcccagaaggcctttcagcatgtagctatgtacgat
accgctatctcccaatatctctggcagggagaagagggcttccccgagaatatgaccata
gccctttccaagcgctatgacctgcgttacggtgaaaatccccatcagccggcagttttc
tatgctgaaaacagggtagggcacgggcagaacaccggcattacctgggcacaacaggcc
tggggcaaacagctttccttcaacaatatcctggatgccgacgccgcctggggagccgcc
actgatttttcggccgccacagtagccatagtcaagcataccaatacctgtggtctgtgc
agccgcgaagacgtagccgaagcctacaagagagctttttccggagaccctgtttcagct
tacgggggcatcgtagcctcaaaccgcaaggtgactctgtccatggccgaagccatgaaa
ggcaccttttatgaaattattattgcccccgaatacgagccggaggcgctggaattcctt
aaaacccgcaaggatttacgcatacttatagccgagcttcccaaacataatgaggccgaa
acccgttcactggattaccgcagggtaaagggagggctgctggtacaagccgctgatgaa
ctggcggaaaatgccgtccagaccaaggtggtaaccaagcgcgaacccacccctgaggaa
atgtcagatttgaaatttgcatggcgggcagtcaagcatatcaaatccaacgccattgtg
ctggctaagaacaatgttctgctgggtatgggagccggacaacccaacagggtagtcagt
gtagacattgccaagagcaaagccggtgaggcttcaaagggtagtgtcatggcctctgac
gccatgttccccttccctgacagcgttgaacaggctgccgctgccggagtgaccgccatt
atccagccgggcggttctatccgtgaccaggagtctattgatgccgccaacaagcataat
atagctatggtctttaccggcacccgccacttccgccattag

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