Drosophila melanogaster (fruit fly): Dmel_CG10123
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Entry
Dmel_CG10123 CDS
T00030
Symbol
Top3alpha
Name
(RefSeq) topoisomerase 3alpha
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
dme
Drosophila melanogaster (fruit fly)
Pathway
dme03440
Homologous recombination
dme03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
Dmel_CG10123 (Top3alpha)
03460 Fanconi anemia pathway
Dmel_CG10123 (Top3alpha)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
dme03032
]
Dmel_CG10123 (Top3alpha)
03400 DNA repair and recombination proteins [BR:
dme03400
]
Dmel_CG10123 (Top3alpha)
Enzymes [BR:
dme01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
Dmel_CG10123 (Top3alpha)
DNA replication proteins [BR:
dme03032
]
Eukaryotic type
DNA Topoisomerases
Dmel_CG10123 (Top3alpha)
DNA repair and recombination proteins [BR:
dme03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
Dmel_CG10123 (Top3alpha)
FA (Fanconi anemia) pathway
Dmel_CG10123 (Top3alpha)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
zf-GRF
Toprim
zf-C4_Topoisom
Motif
Other DBs
NCBI-GeneID:
35236
NCBI-ProteinID:
NP_523602
FlyBase:
FBgn0040268
UniProt:
Q9NG98
LinkDB
All DBs
Position
2L
Genome browser
AA seq
1250 aa
AA seq
DB search
MKAVLTCFRPVVASHRRYCANPGQAMKYLNVAEKNDAAKTIAGLLSNGAAQRREGYSVYN
KVFDFEAPVRGQNAKMVMTSVSGHMMQLAFQVSYKNWRTVDPRSLFDAPVKKGVGSDYEP
IKRTLEREVRGCQGLIIWTDCDREGENIGYEIIDVCRAIKPNISVYRATFSEITTVAVRR
ALQQLGQPDKRQSDAVDVRTELDLRTGAAITRFQTMRLQRLFPEKIADKLISYGSCQIPT
LGFVAERYKEIEAFVSEPFWKIKVLHTIDDLTVEFNWARNRLFDKEACENYLLLCLAEPD
PRALVESVTVKPKHKWRPTPLDTVEMEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTE
TNQFSKEFALAPLVEMQTGHRDWGAFAQRVIEWGPNPRNGNKSDQAHPPIHPTKLAENLQ
GNEARVYELVVRHFLACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKWS
AKQIHHYENGQRFEPTEVSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKE
RGYIGVLDKGFLVPGVIGMGLYEGYDAMELALAKPQLRAEFELDLKLICQGQKDPKVVLT
EQIAKYKQAYQQITDKITAMDAKISARINETPAANSAVQEGADGSAPSHGIIQSIFQCPK
CNEAPLALKPKKNQQGWYIGCNNFPDCKNAVWLPTECKDASVLDECCPTCGDGYRMLKFR
LSTPYYRGVFGTPSGWYKTCLPCDNLFRTTFNINLDSVKKVGGIVGEVRGGGGGPGPGPG
GGGSGRGAGSGGWSSGPGGGGSGGGGGSGGWGSGTGGGGSGGWGSGTGGGGLGGGKGKKP
GGESKKSATKKPPNEPKPKKTKEPKAAPNKKTSSKSSGSIRSFFTSAAPTNSASNGLDEF
FDSNDGFEDAMLAAAESVESSSQPKTISMVPLDDDIAAAFAADDDAEFEALVNGGTMPTE
SNGDQQLDKSLSEWIKEQDKADERPMLWGTRERASLGTAAPTPPPKPAAKRPRWDSVERD
STPPSSVPESETVLCTGCQQPARQNTVRKNGPNLGRLYYKCPKPDECNFFQWADEPPSSA
KSKNSTGSAPQSTTSWGSNRVVTLPSIQQSNSQRGQSSMRSNSSSTVTITQTKTKQQERN
TATPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACPTREKSCGFFKWGDEDQNQGASS
TSWGSANRNPPGRSQPTAITSDGPKTRRCGLCRKEGHTRNKCPRKDEFDM
NT seq
3753 nt
NT seq
+upstream
nt +downstream
nt
atgaaagctgtcttaacatgttttcgccccgtcgtcgcctcacacagaagatattgcgct
aatcccggccaggcaatgaagtacttaaacgtggctgagaagaacgacgccgccaaaacg
attgccggcctgctgtcaaatggcgcagcacaaaggcgcgaaggctactcggtgtacaac
aaggtcttcgatttcgaggcccctgtgcgcggtcagaatgccaaaatggttatgacctcc
gtatccggccacatgatgcagctggcattccaggtgtcttacaaaaattggagaacggtg
gatccgcgctctttattcgacgcgccggtgaaaaagggcgtgggctcggattatgagcct
atcaaaaggaccttggaacgcgaggtgcgcggctgtcagggattgattatctggacggat
tgcgatcgcgagggcgagaacattggctacgagattattgatgtgtgtcgcgctatcaaa
ccgaatatttcggtttatcgtgccactttctcggagattaccacggtggcggtgcgtcgg
gctctgcagcaattggggcagccggacaaaaggcagagcgatgcagtggatgtgcgcacg
gaactggatttgcgaactggtgccgccatcacccggtttcagacaatgcgcctacaacgt
ctgttccccgaaaagatagctgataagctcatatcctatggaagctgccaaattcccacc
ctgggattcgtcgccgaacggtacaaggagattgaggccttcgtatccgagccattttgg
aagattaaggttctgcacacaattgatgacttgacggtggagtttaattgggcccgaaac
cgactcttcgataaggaagcttgtgaaaactatttgctcctctgcctggccgaacccgat
cctagagcgctcgtggagagcgtcaccgttaagcccaaacacaaatggcgcccaactccg
ctggataccgtggaaatggagaagcttggctcgaggaaactcaagctatctgccaaggag
acgatgacaatagccgaaaaattatataccaagggtttcatcagctatccccgtacggaa
accaaccagttctccaaggagttcgctctggcaccactagttgagatgcaaacgggtcac
cgcgactggggagcatttgcccagcgggtgattgagtggggaccaaatcctcgaaacggt
aacaaatcggatcaggcccatcctccaattcatcccaccaagctggcagaaaacctgcag
ggaaacgaggcgcgagtgtacgaactggtcgtccggcacttcctcgcctgcgtcagcaaa
gatgcagtcggctccgaaacccttgtccatatcgacattgccggtgagaagttcacggcc
aatggtctggttattcacgaacgaaactacctagatgtttatgtttatgacaagtggagt
gccaagcagatccatcactatgaaaacgggcagcgttttgagcccacggaagtgtcgctc
cacgaaggtgccaccactgccccgcccctgctgaccgaagcggatttgattgcactgatg
gaaaagcatgggattggtacagatgccacgcacgctgagcacataaacacgatcaaggaa
cgcggatacatcggagtgctggataagggctttttggtacctggagttattggaatggga
ctgtatgagggatacgatgccatggagctggcccttgccaagccacaacttcgtgctgag
tttgaattggatctgaaactaatttgccaggggcagaaagatcccaaggtggtcctgacc
gaacagatagccaagtacaagcaggcctatcagcagattaccgataagattaccgccatg
gacgccaagatatcggctcgcattaatgagacaccagctgccaattctgcggtgcaggaa
ggagctgatggaagtgctccaagtcacggcatcatccaatcgatcttccagtgccctaag
tgcaatgaggctcctctggccctaaagccaaagaagaaccagcagggctggtacattggc
tgcaataactttcccgactgcaaaaacgcagtttggcttccaacggagtgcaaggacgca
tctgtgctggacgagtgctgtcccacctgtggcgatggataccggatgctcaagttccgc
ctgagcacgccttactatcgcggggtatttggtactcccagcggttggtacaaaacctgc
ttgccctgcgataatctctttcgcaccacgttcaacattaatttggactcggttaagaaa
gtgggaggcattgtgggtgaagtgcgtggtggaggagggggtccaggcccaggacccggt
ggcggtggctctggcagaggagccggctctggtggatggagcagcggacctggaggcggt
ggctctggcggaggcggcggctctggaggatggggcagcggaactggaggcggtggctct
ggaggatggggcagcggaactggaggcggtggcttgggcggaggaaagggcaagaaacct
ggcggcgaatctaaaaaatcagctacaaaaaaacctccgaacgaacccaaaccgaaaaag
acgaaagaaccgaaagcggcacccaacaaaaagactagcagcaaatcgtctggcagcata
cggagcttctttacaagtgcggcgcctacaaattccgccagcaatggactagatgagttt
ttcgatagtaacgatggctttgaggacgccatgttggctgctgccgaatccgtggaatcg
agtagccaacccaaaaccattagtatggtccctcttgatgacgacatagccgccgctttt
gcagcggatgatgatgctgaattcgaggcgttggtaaacggcggaaccatgcccaccgaa
tccaatggggaccagcagctggacaaaagtctctcggaatggataaaggagcaggacaaa
gcggacgagaggcccatgctttggggaactcgggagcgagcgtcgttaggtactgctgct
cccactcctcctccgaaaccggcagctaaacgaccgagatgggacagtgtcgaacgggat
tccacaccaccctcttcggttccggaatccgaaacagtgctgtgtaccggatgtcagcag
ccagctcgccagaacactgtccgtaagaatggacccaacctaggcaggctgtactacaag
tgtcccaaaccggatgagtgcaacttctttcagtgggctgatgagccaccgtcgtcggcc
aaaagcaagaattccaccggcagtgcaccacaaagcacaacatcctggggctccaatcga
gtggttaccctgcctagcattcagcagagcaactcacagcgtggccaatcatctatgcga
tcaaactccagcagtactgtcaccattactcaaacgaaaaccaaacagcaggagaggaat
acagcgactccaggcgacggagaggaggtgatgtgcaactgtgggcagttggctagccag
ctgacggtccgaaaagacggaccaaaccagggtagacccttttatgcctgtcccacgcgg
gagaagtcatgcggtttcttcaaatggggagatgaggaccaaaaccaaggtgctagcagc
acctcttggggctcggctaatcgaaatccccctggacgcagtcagcccacagctattacg
tccgatggtcccaaaacgagacgctgtggtctctgtcgcaaggagggacacacaaggaac
aagtgtccacgcaaggatgagtttgatatgtag
DBGET
integrated database retrieval system
