Drosophila melanogaster (fruit fly): Dmel_CG10223
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Entry
Dmel_CG10223 CDS
T00030
Symbol
Top2
Name
(RefSeq) topoisomerase 2, isoform B
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
dme
Drosophila melanogaster (fruit fly)
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
dme03032
]
Dmel_CG10223 (Top2)
03036 Chromosome and associated proteins [BR:
dme03036
]
Dmel_CG10223 (Top2)
Enzymes [BR:
dme01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
Dmel_CG10223 (Top2)
DNA replication proteins [BR:
dme03032
]
Eukaryotic type
DNA Topoisomerases
Dmel_CG10223 (Top2)
Chromosome and associated proteins [BR:
dme03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
Dmel_CG10223 (Top2)
Centrosome formation proteins
Centriole proteins
Dmel_CG10223 (Top2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
Toprim
HATPase_c
RE_ApaLI
Motif
Other DBs
NCBI-GeneID:
35225
NCBI-ProteinID:
NP_001260580
FlyBase:
FBgn0284220
UniProt:
P15348
LinkDB
All DBs
Position
2L
Genome browser
AA seq
1447 aa
AA seq
DB search
MENGNKALSIEQMYQKKSQLEHILLRPDSYIGSVEFTKELMWVYDNSQNRMVQKEISFVP
GLYKIFDEILVNAADNKQRDKSMNTIKIDIDPERNMVSVWNNGQGIPVTMHKEQKMYVPT
MIFGHLLTSSNYNDDEKKVTGGRNGYGAKLCNIFSTSFTVETATREYKKSFKQTWGNNMG
KASDVQIKDFNGTDYTRITFSPDLAKFKMDRLDEDIVALMSRRAYDVAASSKGVSVFLNG
NKLGVRNFKDYIDLHIKNTDDDSGPPIKIVHEVANERWEVACCPSDRGFQQVSFVNSIAT
YKGGRHVDHVVDNLIKQLLEVLKKKNKGGINIKPFQVRNHLWVFVNCLIENPTFDSQTKE
NMTLQQKGFGSKCTLSEKFINNMSKSGIVESVLAWAKFKAQNDIAKTGGRKSSKIKGIPK
LEDANEAGGKNSIKCTLILTEGDSAKSLAVSGLGVIGRDLYGVFPLRGKLLNVREANFKQ
LSENAEINNLCKIIGLQYKKKYLTEDDLKTLRYGKVMIMTDQDQDGSHIKGLLINFIHTN
WPELLRLPFLEEFITPIVKATKKNEELSFYSLPEFEEWKNDTANHHTYNIKYYKGLGTST
SKEAKEYFQDMDRHRILFKYDGSVDDESIVMAFSKKHIESRKVWLTNHMDEVKRRKELGL
PERYLYTKGTKSITYADFINLELVLFSNADNERSIPSLVDGLKPGQRKVMFTCFKRNDKR
EVKVAQLSGSVAEMSAYHHGEVSLQMTIVNLAQNFVGANNINLLEPRGQFGTRLSGGKDC
ASARYIFTIMSPLTRLIYHPLDDPLLDYQVDDGQKIEPLWYLPIIPMVLVNGAEGIGTGW
STKISNYNPREIMKNLRKMINGQEPSVMHPWYKNFLGRMEYVSDGRYIQTGNIQILSGNR
LEISELPVGVWTQNYKENVLEPLSNGTEKVKGIISEYREYHTDTTVRFVISFAPGEFERI
HAEEGGFYRVFKLTTTLSTNQMHAFDQNNCLRRFPTAIDILKEYYKLRREYYARRRDFLV
GQLTAQADRLSDQARFILEKCEKKLVVENKQRKAMCDELLKRGYRPDPVKEWQRRIKMED
AEQADEEDEEEEEAAPSVSSKAKKEKEVDPEKAFKKLTDVKKFDYLLGMSMWMLTEEKKN
ELLKQRDTKLSELESLRKKTPEMLWLDDLDALESKLNEVEEKERAEEQGINLKTAKALKG
QKSASAKGRKVKSMGGGAGAGDVFPDPDGEPVEFKITEEIIKKMAAAAKVAQAAKEPKKP
KEPKEPKVKKEPKGKQIKAEPDASGDEVDEFDAMVEGGSKTSPKAKKAVVKKEPGEKKPR
QKKENGGGLKQSKIDFSKAKAKKSDDDVEEVTPRAERPGRRQASKKIDYSSLFSDEEEDG
GNVGSDDDGNASDDDSPKRPAKRGREDESSGGAKKKAPPKKRRAVIESDDDDIEIDEDDD
DDSDFNC
NT seq
4344 nt
NT seq
+upstream
nt +downstream
nt
atggagaacggaaacaaggccctgtccatcgaacagatgtaccagaagaagtcgcagctg
gagcacatcctgctgcgacccgactcgtacatcggatccgtggagttcaccaaggagctg
atgtgggtgtatgacaactcccaaaaccgcatggtgcagaaggagatctctttcgtgccc
ggcctctacaagatattcgacgagattcttgtgaatgcggcagataacaagcagcgagac
aagagcatgaacaccattaagatcgacatcgatccggagcgcaatatggtgtccgtgtgg
aacaacggccagggcattccggtgaccatgcacaaggagcagaagatgtacgttccaacg
atgatctttggtcatctgctgacctcgtcgaactacaacgacgatgagaagaaggtcact
ggcggcaggaacggatacggagcgaagctctgcaacatattctccaccagcttcaccgtt
gagactgccacgagggaatacaagaaaagtttcaagcagacttggggaaacaacatggga
aaagcctccgatgtgcagatcaaggacttcaatggcactgactacacacgcatcacattc
agtcccgatctggccaagttcaagatggaccgtctcgatgaagatattgtggctctaatg
tcgcgtcgcgcctacgatgtggccgcctcatccaagggagtatccgtcttcttaaacggc
aacaaactgggtgtacgcaacttcaaggactatattgatttgcacatcaagaacacggac
gacgattctggcccaccgatcaagatagtccacgaggttgccaacgagcgttgggaggtg
gcttgctgtccttcagatcgaggcttccaacaggtctcgtttgtcaactcgatagctacc
tacaagggcggtcggcatgtggaccatgtggtagacaatctcattaagcagctgctcgag
gttctgaagaaaaagaacaaaggtggcatcaacatcaagccattccaggtccgaaaccat
ctgtgggtttttgtcaactgcttgatagagaaccccactttcgactcgcagaccaaggag
aacatgactctgcaacaaaagggcttcggttccaagtgtaccctctcggaaaagttcatc
aacaacatgtccaagtctggcatcgtggagtctgtgctggcatgggccaagttcaaggcc
caaaatgacattgccaagacgggcggtcgcaagtcaagcaagatcaagggcattcccaag
ctggaggacgctaacgaggcgggtggaaagaactcgattaaatgcaccctcatcctcacc
gagggagactcagccaagtcattggccgtatccggtttgggcgtgatcggacgagatctc
tacggcgtgttcccgcttaggggtaaacttctaaatgtgcgggaagctaatttcaagcag
ctttcggagaatgccgaaatcaacaatttatgcaagataattggcttgcaatacaaaaag
aagtacctcactgaggacgatctaaaaactctgcgctatggcaaagtgatgatcatgaca
gatcaggatcaggatggctcccacatcaagggtctcttgatcaactttatccacaccaat
tggccagagcttctgcgtctgcccttcctcgaggagttcattacaccaattgtgaaggca
accaagaaaaacgaggagctgtcattctactcgctacccgaattcgaggagtggaaaaat
gatacagctaatcaccatacgtacaatataaagtactataagggtttgggtacttcgacc
tccaaggaggcgaaagagtattttcaagacatggatcgccatcgcatcttatttaagtac
gatggatcggtggatgatgagagcattgttatggccttctccaagaagcacatcgagtcg
cgaaaggtatggcttaccaaccacatggacgaggtgaagcgtcgcaaggagctcggtttg
ccagagcgatatctctacaccaagggcaccaagagcatcacctatgcagactttatcaat
ctggagttggtgctgttctcgaatgctgacaatgagcgctccattcctagtctggtggat
ggcttgaagccgggtcagcggaaggtgatgttcacttgcttcaagaggaatgacaagcgt
gaggtgaaggtggcccagctatccggatcagtggcggagatgtcagcctatcaccacgga
gaggtatccctacagatgacaatcgtgaatctggctcagaattttgtgggtgccaacaac
attaatctgcttgagccacgcggtcaatttggtacccgcttgtcgggaggcaaagattgc
gccagcgctcgttacattttcactataatgtctcccttgacgcgactcatctaccatcct
ttggacgatccacttttggattaccaggtggacgatggccaaaagatcgagccactatgg
tatctgcccatcataccgatggtattggtaaacggagccgagggcataggaactggatgg
tccacgaagatatccaactacaatcctcgtgagattatgaaaaatctaaggaagatgata
aacggacaagagccaagtgtgatgcatccgtggtacaagaactttttaggacgcatggag
tatgtttcggatggtcgttatattcagactggtaacattcaaattttgtccggaaaccgt
ttagaaatcagtgaactccctgtgggcgtatggacgcaaaactacaaggaaaatgtcctg
gagcctttatcaaacggcaccgaaaaggttaagggtattatttccgagtacagggagtat
catacagacaccaccgttcgctttgtgatcagtttcgcacctggagaatttgagcgcatt
catgcagaagaaggtggtttctaccgagtgttcaaacttaccacgacgctgtccaccaac
cagatgcatgcgttcgaccagaacaactgtctgcgacgcttccccaccgcgatcgatatc
cttaaagagtattacaaactgcgacgagagtactacgcccgccggagggactttttggtc
ggccagctcacggcgcaggctgatcgcctcagtgatcaggcgcgctttattctcgaaaag
tgtgagaagaagctggtggtggagaacaagcagcgcaaggccatgtgtgatgagttgttg
aagcgtggatatcgtcccgatcccgtcaaggagtggcagcgccgcattaaaatggaggat
gccgagcaagctgacgaagaggacgaagaagaagaggaggcagctcccagtgtcagctca
aaggctaagaaggaaaaggaagtcgatccggaaaaggcctttaagaaactaactgatgtc
aaaaagtttgactaccttctgggtatgtccatgtggatgttgacagaggagaagaaaaac
gagctactcaaacagcgcgacactaaactgtccgagttggaaagtctgcgcaagaagacg
ccggagatgctttggctggatgatttggatgccctcgaatcgaagttaaatgaagtagag
gagaaggagcgcgcagaagagcaggggatcaatctcaagaccgcgaaggctttgaagggc
cagaagtcggcctcagctaagggcagaaaggttaagtcaatgggaggcggagcgggtgcc
ggagacgtattcccagatcccgatggagaacccgtcgagtttaagatcaccgaagaaatc
attaagaaaatggcagcggctgccaaggtagctcaggcggctaaggagccgaagaaaccc
aaagagcccaaggagccaaaagtgaagaaggaaccgaagggcaagcagattaaagccgaa
cctgatgccagcggcgatgaggtggacgaatttgatgcaatggtcgagggcggctctaag
acctcacccaaggccaagaaggcggttgtcaagaaggagccgggagaaaaaaagccgcgc
caaaagaaggagaacggcggcgggctcaagcagagcaagattgacttcagcaaggccaag
gcgaaaaagagcgacgatgacgtggaggaagtaactcctcgtgcagagcgtcctggacgt
cgacaggccagtaagaagatagactacagctcgctcttctcggatgaggaggaagacggt
ggcaacgttggctctgatgatgatggcaatgccagcgatgatgattcgcccaagcgtcca
gctaagcgtggacgagaggatgagagcagtggaggagccaaaaagaaagctccgcccaag
aagaggcgagctgtaattgaaagcgatgatgatgatatcgagattgatgaagatgatgat
gatgattctgattttaattgttaa
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integrated database retrieval system
