Drosophila melanogaster (fruit fly): Dmel_CG10844 Help Entry Dmel_CG10844      CDS       T00030                                  Symbol RyR Name (RefSeq) ryanodine receptor, isoform A   KO K04962   ryanodine receptor 2 Organism dme  Drosophila melanogaster (fruit fly) Brite KEGG Orthology (KO) [BR:dme00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:dme04040]     Dmel_CG10844 (RyR)    04990 Domain-containing proteins not elsewhere classified [BR:dme04990]     Dmel_CG10844 (RyR) Ion channels [BR:dme04040]  Voltage-gated cation channels   Ryanodine receptor    Dmel_CG10844 (RyR) Domain-containing proteins not elsewhere classified [BR:dme04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    Dmel_CG10844 (RyR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  49090 NCBI-ProteinID:  NP_476991 FlyBase:  FBgn0011286 UniProt:  Q24498 LinkDB All DBs Position 2R Genome browser AA seq 5127 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVTLSCTATGERVCLAAEGFGNRHCFLENIADKNVPPDLS QCVFVIEQALSVRALQELVTAAGSETGKGTGSGHRTLLYGNAILLRHHNSDMYLACLSTS SSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKE NEQSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWGREAG QNIVIYEGGVVMAQARSLWRLELARTKWTGGFINWYHPMRIRHITTGRYLGVNDSNELIL VKKEEASIATTTFCLRQEKDDEKKVLEDKDLEVIGSPIIKYGDTTVIVQHCETSLWLSYK SYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFITALE TLQSNRRHSIFFQKVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDLFQEE GVLNLILEAIDKINIITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTNCAQF ANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEKHGRD PKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLVDHVASIRPNIFVGRVDGS SMYQKWYFEVTMDHIEQTTHMMPHLRIGWANTSGYVPYPGGGKKWGGNGVGDDLYSFGFD GAFLWTGGRKTLVVDALPEEPFIRKGDVIGVAIDLSVPIITFTFNGVKVRGSFRDFNLDG MFFPVMSCSSKLSCRFLFGGDHGRLKFAPPMGFSALVQCLMPQQILSLDPCFYFGNLAKN VLAGPWLIEDDTAFVPKPVDTTGVTLPSSVDQIKEKLAENIHEMWALNKIEAGWSWGEHR DDYHRIHPCLTHFEKLPAAEKRYDNQLAVQTLKTIISLGYYITMDKPPARIRPVRLPNEI FMQGNGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWARERIQQGWTYGLNEDSENHRS PHLVPYAKVDEAIKKANRDTASETVRTLLVYGYVLDPPTGEGTEALLAEAQRLKFAGFRT YRVERNYAVTSGKWYFEFEVLTSGPMRVGWARADCYPGAMLGSEDTSWAFDGHNVTKMHA GSIEHFGVRYEAGDVIGCFIDVKEQTISFSLNGELLMDALGGETTFADVTAEGVGFVPAC TLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENTEEMP DCRIDVTRIPGGADTPPHLKISHNTFETMEKANWEFLRLSLPVTCMGEFISEQEKARRWD EIKNRQYRLMREAEIAAQMQVQTQAAHMDHMLKGGFNMNDIKGLTRNFDEHADAEADHMM RGPNRPPRKGSLTRNITFETDMSAALDEMQRSTSVLDMNGLGEEMDDKKKRGRSPFKFFS KKSRDQSREKMGARTLDTSLERRNTVAHGRNVVNQQMTTRAPTLRLNNAEIPPSPVPQGP KQLSGSNLGQQPVETSGDEMFDAECLKLINEYFYGVRIFPGQDPTHVYVGWVTTQYHLHS REFNKNKVRRGSVYIEDDYEMAIERIDRQSCYVVRADELFNEVTQDASGKGASQGMFVGC FVDTATGIIRFTCEGKDTSHRWMMEPDTKLFPAIFVEATSKEILQIELGRTPTTLPLSAA VLPTSDKHINPQSPPRLKVQCLRPHQWARVPNTALQVHALKLSDVRGWSMLCEDPVSMLA LHIPEEDRCIDILELIEMDKLLSFHAHSLTLYAALCYQSNYRAAHALCQHVDQKQLLYAI RSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYITPLGAELKELYSDEEMQHSLRSL VTESVRPQLRMTEITPPVIATSSMPSVSSEPIPDIDQLYSPKFPLEVVRQFVMEALKDAV EINQVHNRDPIGWTNENLFLPLIKLTDRLLLVGVLTDEDVQRLLVMIDPETWDQAFEREG KDEHRKGLLTMKMAEGAKLQMCYLLHHLYDTQLRHRVESIIAFSHDFVGDLQTDQLRRYI EIKQSDLPSAVAAKKTKEFRCPPREQMNQILCFKNLEPDDQDNCTCGLELRGRLGDFHDS LMQKVSLNALQEPDGVEGTAIEEVKTGPITKIYNFINTVKELEEGPKEVEEPEKKTPEEV FRKVLIKTIVSWAEESQIENPKLVREMFSLLLRQYDTVGELVRALEKTYVINTRARDDVA EMWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNATFFQHPDLIRILRVHENVMAVMMN TLGRRAQAQSDAPTQSEVAEGAPSKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFDHFD FLLDNANILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNSE LVEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLGPALRGEG EGLFRAIVEANRMSERISDRCKMQDEAEGTIAGLNFTHPLPEGEEDEDYIDTGAAILNFY CTLVDLLGRCAPDASVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTLSQTAPGEEKP KSDMPSGLLPNNKQSIVLFLERVYGIEAQDLFYRLLEDAFLPDLRTATILDKSDGSESDM ALAMNRYIGNSILPLLIKHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVSDF LVALTSQMQPAMLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYGSTQGQGSYGA SSDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTDEDYYG RQMGAPDQPQYMPNPIDTNNVHLDNDLNSLVQKFSEHYHDAWASRRLEGGWTYGDIRSDN DRKHPRLKPYNMLSEYERERYRDPVRECLKGLLAIGWTVEHSEVEVALNHRGSTRRQSKP QINEFQNEGSPFNYNPHPVDMSNLTLSREMQNMAERLAENSHDIWAKKKNEELNGCGGVI HPQLVPYDLLTDKEKKKDRERSQEFLKYMQYQGYKLHKPSKGGAVEEGGATQAAVELRFS YSLLEKLIQYLDRATINMKLLKPSTTFSRRSSFKTATRDIKFFSKVVLPLMEKYFSTHRN YFIAIATATNNIGAASLKEKEMVASIFCKLAALLRNRLSAFGPDVRITVRCLQVLVKGID ARTLTKNCPEFIRTSMLTFFNQTSDDLGNTILNLQDGKYSHLRGTHLKTSTSLGYVNQVV LPVLTAMFDHLAACDYGSDLLLDEIQVASYKILAALYHLGTDGTLTHDRKYLKTEIERHR PALGSCLGAYSSCFPVAFLEPHLNKHNQYSLLNRIADHSLEAQDIMVKMESCMPNLETIL AEVDQFVESDKTYNDAPHIIDVILPLLCAYLPFWWSQGPDNVSPTSGNHVTMVTADHMNP LLRNVLKMIKKNIGNDNAPWMTRIAAYTQQIIINTSEELLKDPFLPLAERVKKRTENMLH KEDSMRGFIKSATDDTSQVETQLQEDWNLLVRDIYSFYPLLIKYVDLQRNHWLKDNIPEA EELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRSAISEGAPAVGGKV KKKKKNRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLKKMPEYD VIEFARNQLTLPDKLDPSDEMSWQHYLYSKLGKTEEPVDEQALEKANVNSNEKGKDKTQE TVDRIVAMAKVLFGLHMIDHPQQQSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRACN IFARSYYEQWLQEENVGQEVMVEDLTQTFEDSEKSKKEGEETDSKPDPLTQLVTTFCRGA MTERSGALQEDLLYMSYAQIAAKSTGKEEEEGGDEEGGEGGEEGEGTSIHEQEMEKQKLL FHQARLSNRGVAEMVLLHISASKGIPSEMVMTTLNLGIAILRGGNIDIQMGMLNHLKEKK DVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCALFRFIQL TCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKAN FFKAIEVASQVFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQV DLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLAD LIESPSFHEVDMKNEGWVTPKDFREKMEQSKNYTPEEMDFLLACCERNHEGKIDYRAFVE HFHEPSKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGSSKRI ERVYFEIKDSNIEQWEKPQIRESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASG LMATDDGGGNVKRDTAYSSYMSEEEEERAARDPIRRTITAVKEGLKFGVHMLSPANIKHQ IGVMQTKSIPELIVGFFKIIFYIFYYTGYAHFCVVRYIFGILLNLMRGPAPEQEEEPVVE EETFGRALPPLPLEEPPGTVQAFGLDINKEENGMYKVVVHESPANSSMEEGGESSPEDGA AASGELVEGEPHQEPISIVDLLGGEAAKKAAQERQEAQKAQEAAMASIEAEAKKSSSAPQ ETPAVHQIDFSQYTHRAVSFLARNFYNLKYVALVLAFSINFMLLFYKVTSFTEEADSSAE EELILGSGSGGGADITGSGFGGSGDGGSGDGEMEDEIPELVHVDEDFFYMEHVLRIAACL HSLVSLAMLIAYYHLKVPLAIFKREKEIARRLEFEGLFIAEQPEDDDFKSHWDKLVISAK SFPVNYWDKFVKKKVRQKYSETYDFDSISNLLGMEKSTFAAQESEETGIFKYIMNIDWRY QVWKAGVTFTDNAFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGK QLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDKKCHDMLTCFVFHLYKGVRAGGG IGDEIGDPDGDDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMES NCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQ RSWDFFPVGDCFRKQYEDELSGGGGGG NT seq 15384 nt NT seq  +upstreamnt  +downstreamnt atggctgaggcggagggaggctccgagcaggatgatgtttcattcctgagaacggaggac atggtcacgctctcctgcacggcgacgggggagcgtgtctgcttggccgccgaaggattt ggcaaccggcactgctttctcgagaatattgccgacaagaacgtgccgccggatctttcg cagtgtgtcttcgtcatcgagcaggcgctgtccgtgcgagcattgcaggagttggtgacg gcggcaggatccgagactggcaaaggcaccggatcgggacacaggacattgctctatggc aatgccattttgctgcgtcaccacaacagtgatatgtacttggcatgtctgtccacctcc tcgtcgaacgacaagctgtccttcgacgtgggcctgcaggagcacagccagggagaggct tgttggtggacggttcatccggcgagcaagcagcgctctgagggcgagaaggtgcgcgtc ggagatgatctgatcctggtgtccgtggccaccgaacgttatttgcatacgaccaaggag aacgaacagtctattgtaaatgccagcttccatgtgacccactggtccgtgcagccctac ggcacgggcatctccaggatgaagtacgtgggctatgtctttggcggcgatgtgctgcgt ttcttccatggtggcgacgagtgcctgaccataccgagtacatggggtcgtgaggcggga caaaatattgttatttacgagggcggcgtggtcatggcacaggcgaggtccctgtggcgc ctggaactcgctcgaaccaagtggactggtggctttatcaactggtaccacccgatgcgc atacgccacataaccactggacgctacttgggcgtcaacgacagcaacgaactgattcta gttaagaaggaggaggcttcgattgccacgacgactttctgcctgcggcaggaaaaggac gacgagaaaaaggtgctggaggacaaggacctggaggtgatcggctcgccgatcatcaag tacggcgacactaccgtcatcgttcagcactgcgagactagcttgtggctcagctacaag agttatgagacgaaaaagaagggcgtaggaaaggtggaggagaagcaagcgatcctgcac gaggagggcaagatggacgattgtctcgacttctcgcgctcccaggaggaggagtccaag acagctcgtgtcatccgcaagtgcagcagcctcttcacccagtttattacagccttggaa acactgcagtcaaatcgccgacactccattttcttccaaaaggtcaacctcaacgagatg gtcatgtgccttgaggacttgattaactacttttcgcaacccgaagacgatatggagcac gaggagaaacagaaccgattccgtgccctgcgcaaccgacaggatctgttccaggaggag ggcgtgctcaatctgatcctggaggccattgacaagatcaacataatcacctcgcagggc ttcctagccagcttcctggccggcgacgagaccggccagagctgggatctcatctccacc tatttgtaccaactcttggccgccatcatcaagggcaaccacacgaactgcgcccagttc gcgaacagtaaccgactcaactggctattctcccgcctcggttcccaggcctccagcgag ggttccggcatgttggacgtacttcactgcgtgctgatcgattcgccagaggcactaaac atgatgcgggatgagcacatcaaggtgatcatctccctgctggagaagcacggcagggac ccgaaagtcctagacgttctgtgttccttgtgcgtgggtaatggagtggcggtgcgatcc tcccagaacaacatttgcgactttttgctaccgggcaagaatctgttgctacagacgctc ctggtggaccatgtggccagcatccgaccgaacatcttcgtgggtcgcgtggacggttct tccatgtaccagaagtggtacttcgaggtgaccatggatcacatcgaacagaccacgcac atgatgccccacctgcgcattggctgggctaatacttccgggtatgtaccgtatcccgga ggcggcaagaagtggggtggcaatggagtaggcgatgacctgtactcctttggatttgat ggtgcctttctttggacgggaggtcgcaaaacactagtggtggacgcgctgcccgaggag ccctttatccgtaaaggcgatgttattggcgttgccattgacctttctgtgcccatcatc acgtttacttttaacggagtaaaagtgcgcggtagctttagggactttaacctggacgga atgttctttcccgtgatgagttgctcatcaaaactaagctgtcgcttccttttcggaggt gatcatggtcgtttaaagtttgccccgcccatgggattctctgccctcgtgcagtgtctc atgccgcagcagatcctcagtctggatccttgcttctactttggtaatcttgccaagaat gttttggccggaccatggcttattgaggacgacactgcttttgttccgaagcccgttgat accacgggtgtgacattgccaagttctgtggaccaaatcaaggagaagctggcggagaat atccacgagatgtgggctctaaacaaaatcgaggcgggctggtcgtggggcgagcaccga gatgactaccaccgcatccatccttgcctcacccatttcgagaagcttccggcggcggaa aagcgatacgacaatcaactagctgtgcaaacgctgaagacgattatctcgctgggatac tacataaccatggacaagccaccagcacgcattcgcccagtgcgcctgcccaacgagatc ttcatgcagggcaatggctacaagccggctccacttgacctaagcgccgtgacactcacc cccaagttggaggagcttgtggaccagctggccgagaacactcacaatctgtgggcacgg gagcgcatccagcagggttggacttatggtctgaacgaggatagtgaaaaccacaggagt ccacacttggtgccatatgccaaagtggacgaggctatcaagaaggccaacagggacaca gcgtcggagacagtgcgaacgctcctggtttacggatatgtcttggatcctccgactggc gaaggaacggaggcacttctggccgaggcacaacgcctcaagttcgccggattccggact tacagggtggagcgcaactacgccgtgacatcgggcaagtggtacttcgaattcgaggtc ctcacgtccggaccaatgcgagtgggttgggcacgggccgattgctatccgggagcgatg ctgggcagcgaggacaccagttgggccttcgatggacacaatgtgaccaaaatgcacgcc ggatccattgagcacttcggagtgcggtatgaggctggcgatgtcattggttgtttcatc gatgtcaaggagcaaacgatcagcttctcgttgaacggagaactcctgatggacgcgctg ggcggcgagacgacctttgccgacgtaaccgccgagggggtgggcttcgtgcccgcctgc accctgggagtgggccagaaggcgcgcctcatctacggccaggacgtggactcactcaag ttcttcaccacttgtggcctgcaagagggatacgagccgttctgcgtgaacatgcgccgc ccggttacccactggtacaccaaggaccagcccatttttgagaacaccgaggagatgccc gactgccgcatcgatgtcacccggattcccggcggcgccgacaccccgccgcacttaaag atctcgcacaacaccttcgagaccatggagaaggccaactgggagttcctgcgtctttcc ctgcccgtgacctgcatgggtgagtttatcagcgaacaggagaaggccagacgctgggac gagattaagaaccggcagtaccgactgatgcgcgaggcggagatcgctgcccaaatgcag gtccagacacaggccgcccacatggaccacatgttgaaaggtggcttcaatatgaacgac atcaagggcttgacccgtaatttcgatgagcacgcggatgctgaggcagatcacatgatg cgcggacccaaccgtccgcctcgcaagggatcgctcacccgcaacataaccttcgaaaca gacatgtccgccgccttggacgagatgcagcgttccacgtcggtgcttgacatgaacggg ctgggcgaagagatggatgacaagaagaagcgcggccgcagcccctttaagttcttctcg aagaagtcgcgtgatcagagccgcgaaaagatgggtgctcgcaccctggacacctctctg gagcgccgaaatacggtggctcatggtcggaacgtggttaaccagcagatgaccacacga gctccaactctgcggttaaataatgccgaaatccctcccagccctgtgccccagggacca aagcagttgagtggctcaaatcttggccaacagccggtggaaacttcgggtgacgagatg ttcgatgccgagtgcctcaagttgatcaacgagtatttctatggagtaagaatctttccc ggtcaggatcccacgcacgtgtacgtcggttgggtcactacgcagtatcacctgcacagc cgtgagtttaacaagaacaaggttcgccgtggatcagtctacatcgaggatgactacgag atggccattgaacggatcgaccgccagagttgctatgtagttcgagcggacgagctcttc aacgaggttacccaggatgcctcaggcaagggagcctcacagggcatgttcgttggctgc ttcgtggacacagccaccggcatcatccgcttcacttgcgagggcaaggacacctctcac cgctggatgatggagccagacaccaagctcttcccggccattttcgtggaagccaccagc aaggagatccttcagatcgagttgggacgtacccctaccacattgcccctttcggcggcg gtactgcccaccagtgacaagcatataaatccacagtccccgccgcgtctgaaggtccag tgcctgcgtccgcatcagtgggctagagttccaaatactgcgctccaggtgcatgcgctg aaactctccgacgtgaggggttggtccatgttgtgcgaggaccccgtgtccatgctggcc ctgcacatcccagaggaggatcgctgtatagatattctggagctcatcgagatggacaag cttttgtccttccatgcccacagtctaacgctctatgcggctctttgttaccaatccaat tacagagctgcccatgccctgtgccagcatgtggaccagaagcagctgctctacgccatc cggtcggagtacatgagcggaccactgcggcagggcttctacgacctgctgatcgccctg catctggagtcgcatgccacaaccatggaggtgtgcaagaacgagtacatcacaccgctg ggagccgagctcaaggaactgtactccgatgaggagatgcagcactcactgagatccctg gttacggagtcagtgcgtccgcagctgcggatgacggagatcacaccccctgtgattgca acatctagtatgccaagtgtttccagcgaaccgatccccgacatcgaccaattgtactcc ccgaagttccccctagaagtagtcaggcagtttgtcatggaggcgctgaaggatgccgtc gagatcaatcaggtgcacaaccgcgatcccatcggctggaccaacgagaacctcttcctc cctctaatcaagctcacagaccggctactcttggtcggcgtcctgactgacgaagatgtc cagcggctattggtcatgatcgacccggagacctgggaccaagccttcgaaagagagggt aaggatgagcaccgcaagggcttgctcaccatgaagatggccgagggcgccaagctgcag atgtgctacctgctgcaccatctctacgacacccagctgcgccatcgagtggagagcatc atcgcgttctcccacgacttcgttggcgacctgcagaccgatcagttgcgacgttatatc gagatcaagcaatccgatttgcccagtgctgttgcggccaaaaagactaaagagttccgc tgtccgccacgggagcagatgaaccagattctctgcttcaagaacctcgaacccgatgac caggacaactgcacctgtggccttgagttgcgcggacgcttgggcgatttccacgattcc ctcatgcaaaaagtgtcgctcaatgctctccaggagccggatggcgtcgagggcacagcg atcgaggaggtaaagacaggacccatcacgaagatctacaactttattaacaccgtcaag gagctggaggagggccccaaggaggtggaggagccggagaagaagacaccagaggaggtg ttccgcaaagttctcattaagacgatcgtcagctgggccgaggagtcacagatcgagaat cccaaactggtgcgcgagatgtttagtctgctgctgcggcagtacgacaccgtcggagaa ttggttcgtgccctggagaagacgtacgtgataaacacccgagcccgcgacgacgtggca gagatgtgggtgggcctcagccagattcgcgccctgctgcccgtccagatgagccaggaa gaggaggaactgatgcgcaagcggctgtggaagctggttaacaacgccaccttctttcag cacccggacctcatacgcatcctgcgtgtccacgagaacgtgatggcagtgatgatgaac acactcggacggagggcacaggcacaaagcgatgcgcccacccagtcggaggtagccgaa ggagctccgtccaaggagaaggacacctcccacgaaatggtggtagcttgctgccgattc ctctgctacttctgtcgcactggtcgccaaaaccaaaaggccatgtttgatcacttcgac tttctgctggacaacgccaacatcctgctggcacggccaagcctgcgaggatccacgccc ctcgatgtggcatactcgagtttgatggagaacacagaattggctctggccctgagggaa cactatctagaaaagatcgccgtctacctctcgcgatgcggactacagagcaactcggag ctcgtggagaagggctatccggatctgggttgggatcccgtcgaaggtgagcgttacctg gacttcctgcgctattgcgtttgggtcaacggcgagagcgtcgaggagaatgcgaacctt gtcattcgacttcttatccgtcgtccggaatgcttgggaccggctctaagaggagaagga gaaggtctgttccgcgccatcgtcgaggctaatcgcatgtcggagcgcatctcggaccgc tgcaagatgcaggacgaggccgagggcaccattgccggtctaaacttcacacatcctctg ccggaaggcgaggaggacgaggactatatcgataccggtgccgccattctgaacttctac tgcacccttgtggacctactgggccgctgcgctccggacgcttcggtcatcgagcagggc aagaacgagtccctgagggctagagctattctgagatctctggtgccactggaggatttg cagggggtgctcagcctgaaattcaccctctcacagacggcgcccggcgaggagaagccc aaatcggacatgccgtccggcctgctacccaacaataagcagagcatcgtgctcttcctg gagcgcgtctacggcatcgaggcacaggacctcttctaccgcctgctggaggacgccttc cttccggatctccgcaccgccaccattctggacaagagcgatggatccgagagcgacatg gcgctggccatgaaccgctacataggcaactcgatcctgccgctgctcatcaagcactcc aagttttacaacgaggccgagaactacgcgagcctcttggatgccactttgcacacggtc taccggctgtccaagaaccgtatgctgaccaaggggcaacgcgaggctgtttccgacttc ctggtggccctcacatcccaaatgcaacctgccatgctgctcaagctgctgcgcaagttg actgtggatgtgtccaagctgtccgagtacaccaccgtggccctccggcttctcaccctg cacttcgatcgctgcgccaaatactacggctcaactcaaggccagggctcctatggagcc tcatcggacgaggagaagcgcctgacgatgctgctgttctcgaacatttttgactcgctc agcaacatggactatgacccggaactgttcggtaaggcactgccctgtctgatcgccatc ggctgcgccctgccaccggactacagcctgtccaagaacacggacgaggactactacggc cgccagatgggcgcaccggatcagccgcagtacatgcccaatccgatcgacaccaacaac gtgcatctggacaacgacctcaactcgctggtccagaagttcagcgagcactaccacgat gcgtgggccagtcggcggttggagggtggctggacctacggagacatccgatccgataat gatcgcaagcatcctcgcctgaagccctacaacatgctcagtgaatacgaacgcgagcgg taccgggatccggtgcgagagtgcctgaagggtctgctggccatcggatggaccgtggag cactccgaggtggaggtggcgctgaatcatcgcggatcaacgcggcgtcagtcgaagcct caaattaacgaattccagaacgagggcagcccgttcaactataacccgcacccggtggac atgagcaacctgaccctgagcagggagatgcagaacatggctgagcgcctggcggagaat tcccacgacatctgggccaagaagaagaacgaggagctcaacggctgcggtggcgttatc catccgcaactggtgccatatgatcttctgaccgacaaagagaagaagaaggatcgcgag cgctcgcaggagttccttaagtacatgcaataccagggttacaagctgcacaagccatca aagggaggagctgtggaggagggcggcgccacccaggctgccgttgaactgcgtttctcg tactccctactggaaaagctcatacagtatctggatagagccaccatcaacatgaaactg ctaaagccatcgaccacgttcagtcgacgctcatcctttaagacggccacccgggacatc aagttcttctcgaaggtggtgctgcctctaatggagaagtacttctcaacgcatcgcaac tacttcatcgccattgccacggcaaccaataatattggagcagcctcgctcaaggagaag gaaatggtggcctcgatcttctgcaagctggccgctctactgcgtaaccggctgagtgca tttggaccggatgtccgcatcacagtacggtgcctccaggtcctggtcaagggcattgat gcacgcaccctgaccaagaattgtcccgagtttattcgcacctccatgctgaccttcttc aaccagacatccgatgacttgggtaacacgatccttaacctgcaggatggcaagtacagt cacctgagaggcactcacctgaaaacctccacatcgttgggatatgtaaaccaggtggtt ttgccggtgcttactgccatgtttgatcatctggcagcctgcgactatggcagcgatttg cttctggacgagattcaggtggcttcctacaagatcctcgctgcactgtatcatttgggt accgatggcaccctgacgcatgacaggaagtatcttaagaccgagattgagaggcataga cccgctctgggctcctgtctgggagcttacagctcctgctttccggtggccttcttggag ccccaccttaacaagcacaaccagtactcgctgctcaaccgtattgcggatcactcactg gaggcgcaggacattatggtcaagatggagagctgtatgccaaatctagagaccattctc gccgaggtcgaccagtttgtggagtcggacaagacatacaatgatgcgcctcatattatc gacgtgatcctgccgctgctttgcgcctatctaccgttttggtggtcccagggaccggat aatgtcagtcccaccagtggcaaccacgtgaccatggtcacagccgatcacatgaatccg ttgctgcgaaatgtgcttaaaatgatcaagaagaacattggcaacgataacgccccttgg atgactcgcattgccgcctatacgcagcagattatcatcaatacgtcggaggagctgctc aaggatccgttcttgccgctggcggagcgggtgaagaagcgcactgagaacatgctgcac aaggaggacagcatgcgaggattcatcaagtcggccacggacgacacttcgcaggtggag acccagctgcaggaggactggaatctgctagtgcgagacatatactcgttctatcccctg ctcatcaagtacgtggatctgcagcgaaaccactggctgaaggacaacataccggaggcc gaggagctctacaaccatgtggcagagatcttcaatatatggtctaagagccagtacttc cttaaggaggagcagaacttcatctctgccaatgagatcgacaacatggccttgatcatg ccaactgcaaccaggaggtcggccatctcggaaggtgctcctgctgtgggtggcaaggta aagaagaagaagaagaacagggacaagaagcgcgacaaggacaaggaggtgcaggccagt ctgatggtggcctgcctgaaacgcctcctacccgttggactgaatctgttcgcgggtcga gagcaggaactggtgcagcactgcaaggatcggtacctgaagaagatgcccgagtacgat gtgatcgagttcgcccgcaaccagctgaccctgccggataagctggacccgtcggacgag atgtcctggcagcattacctttactcaaagctgggcaagacggaggaaccggtggacgaa caggcgctggagaaggccaatgttaactccaacgagaagggcaaggacaaaacccaggag acagtggatcgcatcgtggcgatggccaaggttctgtttggcctgcacatgatcgaccat ccacaacagcagagcaagaatgtctacaggagcgttgtgtcgatccaaaggaagcgtgcc gtaatcgcatgcttccgtcagacatcgctgcattctctacccagacatcgggcctgcaac atcttcgcacgatcgtactacgagcagtggctgcaggaggagaacgtgggccaagaggtg atggtcgaagatctgacgcagacgttcgaggactccgagaaatccaagaaggagggcgag gagacggacagcaagccggatccgctaacccaactggttaccactttctgccgcggcgcc atgacggaacgcagcggtgccctccaggaggatctgctctacatgtcctatgcccagatc gcggccaagtccacgggcaaggaggaggaggaaggcggcgacgaggaaggcggtgagggt ggcgaagagggcgaaggcaccagcatccatgaacaagagatggagaagcagaagctgctc ttccatcaggcacgtctctccaatcgtggcgttgccgaaatggtgctgttgcacatttcc gcctccaaaggtataccttcggagatggtaatgacgacactcaatctcggcatcgccatt ttgcgcggcggcaacatcgacatccaaatgggcatgctgaaccacttgaaggaaaagaag gacgttggcttctttacctccatcgccggactgatgaactcctgcagtgtactggacctg gacgcctttgagcgaaacaccaaagcagagggtcttggtgtaggttccgaaggcgccgcg ggcgagaagaacatgcacgacgcggagttcacctgtgcgctgttccggttcatccagctg acctgcgagggccacaacttggaatggcaaaactatttgaggacccaggcgggtaacacc accaccgtgaacgtggtcatctgtactgtggattatttgcttcgtctgcaagagtccatc atggacttctactggcactactccagcaaagagatcatcgatcccgctggaaaggccaac ttcttcaaggccatcgaagtggctagccaagtatttaacaccctcactgaagtcatccag ggtccgtgtaccctcaatcagcaggccttggcacactcgaggttgtgggatgcagttggt ggcttcctcttcctgttttcccacatgcaggacaagctgtcaaagcactccagccaagtt gatctgctcaaggaactgctgaatctgcaaaaggacatgatcaccatgatgctttccatg ctggaaggaaatgttgttaacggcactattggcaagcagatggtggacacgctggtggag tctgccagcaatgtggagctgattcttaagtacttcgacatgttcctgaagctcgccgac cttatcgaatcgcccagcttccacgaagtggacatgaagaacgagggttgggtgaccccc aaagactttagggaaaagatggagcaatccaagaactacacaccggaagaaatggatttc cttttggcctgctgcgagcgcaaccacgagggcaagatcgattaccgggccttcgtggag cacttccacgaaccatcaaaggagatcggtttcaacctggctgtgctcctgaccaacctc agcgaacacatgccaaacgaaccgcgcctggcgcgcttcctggagaccgccggctcggtg ctcaactacttcgagcccttcctgggccgcatcgagattctcggcagctccaagcgcatc gagcgcgtttactttgagatcaaggactcgaacatcgaacagtgggagaagccccagatt cgcgagtccaagcgtgccttcttttattccatcgtcaccgaaggtggcgacaaggagaaa ctggaggcctttgtgaacttctgcgaggacgccatctttgagatgacccacgcctcggga cttatggccaccgatgatggcggtggcaatgtgaagcgggacactgcctatagttcctat atgagcgaggaagaggaggagcgagccgctcgtgatcccatccgccgcaccatcaccgcc gtcaaagaaggactcaagttcggagtgcacatgcttagtccggcgaacatcaagcatcag atcggagtgatgcagaccaaatccataccagaactcatagtcggctttttcaagatcatc ttctatatattttactataccggatatgcacacttctgcgtggtgcgttacatattcggc atcctactgaacctgatgcgaggacctgctccagagcaggaggaggaaccggtagtggag gaggaaacgtttggaagagcactgccaccgctgccgcttgaagaaccaccgggcacggtg caagcctttgggctggacatcaacaaggaggagaacggcatgtacaaggtggtggtgcac gaatctccagccaattcctcgatggaggagggcggagaatccagtcccgaggacggagca gctgccagcggcgaattggtcgaaggtgaaccacaccaggagcccatttccattgtggat ctgctgggtggagaggctgcaaagaaggcggcacaggagcggcaggaggcgcaaaaggct caggaggccgctatggcctccatcgaggcggaagccaagaagtcgtcatctgcgcctcag gagactccagctgttcaccagatcgacttttctcagtacacccatcgcgccgttagcttc ctcgccagaaacttctacaacctcaagtatgtggccttggtgctggctttcagcattaac ttcatgctgctcttctacaaagtcacctcgtttaccgaagaagcagacagctctgccgaa gaggagctcatcctgggctccgggtcgggaggaggtgcggacatcacgggctctgggttt ggcggatcaggggacggaggatcgggcgatggcgaaatggaggacgagataccggaactt gtgcacgtggacgaagacttcttctacatggaacacgttctccgcattgcggcatgtctg cactcacttgtctccctggccatgttgattgcctactaccacctcaaggttccattggcc atcttcaagcgggaaaaagagattgcccgccggctggagttcgagggattgttcattgca gagcagccggaggatgacgacttcaagtcgcactgggacaagctggtaatttcggcgaaa agtttcccggtgaactactgggacaagttcgtgaagaagaaggtgcgccaaaagtacagc gagacctacgactttgattcgatctctaatctgctgggcatggagaagagcacgttcgcg gctcaggagagcgaggaaacgggcatcttcaagtacatcatgaacatcgactggcgctat caggtgtggaaggctggcgtcaccttcacggacaacgccttcctctactcgctgtggtac ttcagcttctcggtgatgggtaacttcaacaacttcttcttcgccgcccatctgctcgat gtggccgtgggcttcaagaccctgcgcaccatcctgcagtctgtgacccacaacggcaag caactggtgctcaccgtgatgctgcttaccatcatagtgtacatctacactgtgatcgcg ttcaacttcttcaggaagttctacatccaggaggaggacgaggaggtggacaaaaagtgc cacgacatgttgacctgcttcgtgttccatctgtacaagggtgtgagagcgggcggtgga ataggcgacgagatcggggatccagatggagacgactacgaggtctaccgcatcatcttc gatatcacgttcttcttcttcgttattattattctgctggccattatccagggtctgatc atcgacgccttcggcgagctgcgtgaccaactggagtcggtgaaggacaacatggagtcc aactgcttcatctgcgggatgggcaaggacttcttcgacatagtaccgcacggcttcgac acgcacgtccagaaggagcacaacttagccaactacatgttcttcctgatgcatttgatt aacaagccggacacggagtataccggccaggagacgtacgtgtggaacatgtaccagcag cgcagctgggacttcttcccagtgggagactgcttccgcaagcaatacgaggatgagctt tccggcggaggcggcggcggctaa

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