Drosophila melanogaster (fruit fly): Dmel_CG31628
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Entry
Dmel_CG31628 CDS
T00030
Symbol
Gart
Name
(RefSeq) GART trifunctional enzyme, isoform C
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
dme
Drosophila melanogaster (fruit fly)
Pathway
dme00230
Purine metabolism
dme00670
One carbon pool by folate
dme01100
Metabolic pathways
Module
dme_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Dmel_CG31628 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
Dmel_CG31628 (Gart)
Enzymes [BR:
dme01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
Dmel_CG31628 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
Dmel_CG31628 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
Dmel_CG31628 (Gart)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
AIRS
GARS_C
ATP-grasp
ATP-grasp_3
CPSase_L_D2
ATP-grasp_2
ATP-grasp_4
RimK
ATPgrasp_ST
Motif
Other DBs
NCBI-GeneID:
33986
NCBI-ProteinID:
NP_001285698
FlyBase:
FBgn0000053
UniProt:
P00967
X2J516
LinkDB
All DBs
Position
2L
Genome browser
AA seq
1353 aa
AA seq
DB search
MSHRVLVIGSGGREHAICWKLSQSPKVAQIYALPGSHGIQLVEKCRNLDAKTLDPKDFEA
IAKWSKENQIALVVVGPEDPLALGLGDVLQSAGIPCFGPGKQGAQIEADKKWAKDFMLRH
GIPTARYESFTDTEKAKAFIRSAPYPALVVKAAGLAAGKGVVVAANAKEACQAVDEILGD
LKYGQAGATLVVEELLEGEEVSVLAFTDGKSVRAMLPAQDHKRLGNGDTGPNTGGMGAYC
PCPLISQPALELVQKAVLERAVQGLIKERINYQGVLYAGLMLTRDGPRVLEFNCRFGDPE
TQVILPLLESDLFDVMEACCSGKLDKIPLQWRNGVSAVGVILASAGYPETSTKGCIISGL
PAANTPTQLVFHSGLAVNAQKEALTNGGRVLIAIALDGSLKEAAAKATKLAGSISFSGSG
AQYRTDIAQKAFKIASASTPGLSYKDSGVDIDAGDALVQRIKPLSRGTQRPGVIGGLGGF
GGLFRLKELTYKEPVIAEATQGVGAKIHLALTHELYENVGYDLFALAANDVLEVGAEPVA
FLDYIACGKLQVPLAAQLVKGMADGCRDARCALVGGETAEMPSLYAPGQHDMAGYCVGIV
EQSRILPRFDLYQPGDLLIGLPSSGLHCAGFNEILTQLAASKVNLRERSPVDGGDDGLTL
AHVLATPTQLYVQQLLPHLQKGDEIKSVAHVTHGLLNDILRLLPDGFETTLDFGAVPVPK
IFGWLAGKLKLSAQTILERHNCGIGMVLILPQSSQLWRTSLPGAKVLGVLQRRSKVSGSP
VQVRNFVEQLEKVASPFGGLGDRELPEELKKLPSNSDLSAPREECFENAAGRRLTRIPTH
YKDPILILGTDGVGTKLKIAQQTNRNTSVGIDLVAMCVNDILCNGAEPISFSSYYACGHW
QEQLAKEVHSGVQEGARQANSSFIDSHSAALPLLYEPQVYDLAGFALGIAEHTGILPLLD
EIQPGDVLIGLPSSGVHSNGFSLVHAVLKRVGLGLHDKAPFSDKTLGEELLVPTKIYVKA
LSTLLSRGKHGIKALAHITGGGLSENIPRVLRKDLAVRLDANKFQLPPVFAWLAAAGNIS
STELQRTYNCGLGMVLVVAPTEVEDVLKELRYPQRAAVVGEVVARKDPKKSQVVVQNFEA
SLARTQKMLSQRRKRVAVLISGTGSNLQALIDATRDSAQGIHADVVLVISNKTGVLGLQR
ATQAGIPSLVISHKDFASREVYDAELTRNLKAARVDLICLAGFMRVLSAPFVREWRGRLV
NIHPSLLPKYPGLHVQKQALEAGEKESGCTVHFVDEGVDTGAIIVQAAVPILPDDDEDSL
TQRIHKAEHWAFPRALAMLVNGTALISPEVSSQ
NT seq
4062 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcatcgcgttctggtcattggcagcggcggtcgggagcacgcgatctgctggaag
ttgtcgcaatctccgaaggtggcccaaatatacgcactgccgggtagccatggcatccag
ctggtggagaagtgccggaatctggatgccaagaccttggatcctaaggatttcgaggcc
attgctaaatggagcaaggagaaccagatagccctagtggttgtgggacccgaagatccc
ttggctttgggtttgggcgatgtgctgcagagcgctggaattccctgctttggacccggc
aagcaaggtgcccaaatcgaggcggacaagaagtgggccaaggactttatgctgcgccat
gggattcccacagcgcgttacgaaagtttcacagacaccgaaaaggccaaggcattcata
agaagcgctccgtatccagctctggtggtgaaagctgctggattggccgccggaaagggc
gtggtggtggccgccaatgcgaaggaggcctgccaggcggtggacgagatcctgggagat
ctgaaatacggtcaggctggcgccacgctggtggtggaggagctactggagggcgaagag
gtttccgttctggccttcaccgatggcaaaagtgtgcgtgccatgctgccagcgcaggat
cacaagcgactgggcaatggcgatactggaccaaacaccggcggcatgggcgcctactgc
ccttgtccgttgatcagccagccagcactggaactggtgcaaaaggccgtgctggagcgg
gctgtgcagggtctgatcaaggagaggatcaactaccagggtgtactctatgcgggactc
atgctgacacgcgatggtccccgtgtgctggagtttaactgccggtttggagatcccgag
acccaggtgattctgccgctgctcgaaagcgatctgttcgatgtgatggaggcttgttgc
agcggaaagctggacaagattcccctgcaatggcgcaatggagtgagtgccgttggtgtg
atcctggccagtgctggctatccggagacctccacaaagggttgcatcatatcgggactt
ccggctgccaatacacccacccaactggtctttcacagcggccttgccgtgaatgcacaa
aaggaagccctaaccaatggcggtcgcgtcctcatcgcgatcgctctggacggcagcttg
aaggaggctgctgcgaaggcaaccaaattggctggcagcatcagtttttcgggctctgga
gctcagtaccgaacggacattgcccagaaggcgttcaaaattgccagtgccagcaccccg
gggttgagttacaaggacagcggagtggacatcgatgctggagatgcactggtgcaacgc
atcaagcccttgtctcggggtacccagcgcccgggcgtgattggcggcttgggtggattt
ggaggactgttccgtttgaaggaactcacctacaaggagccagtcattgctgaggccact
cagggagtcggagccaagatccatcttgccctgacgcacgaattgtatgaaaatgtgggc
tacgacctgtttgccttggctgctaatgatgtcctggaagtgggtgccgagccggtcgcc
tttctggactacattgcctgtggcaagctgcaagttccattggccgcccagttggtcaag
ggaatggctgatggctgccgggatgcgcggtgcgccttagtgggtggtgagactgcagag
atgccttctctatatgctcccggtcaacacgacatggctggctattgtgttggcatagtg
gagcagtctcgaatcctgccccgtttcgatctttaccagccgggtgacttactcatcggt
ctgccatcatctgggcttcattgcgccggcttcaatgaaatactcacccagttggcggca
tccaaagtgaatctcagagagcgttctcccgtggacggaggcgacgatgggctgaccttg
gcccatgtcttagccacgcccacccaactgtatgtccagcagctgttgcctcatcttcag
aaaggagatgagatcaagtcggtggctcacgtgacccatggtctgctaaacgatatcctc
cgtctgcttcccgatggatttgagacaacgctggatttcggtgccgtcccagtgcccaaa
atctttggttggctggccggaaagctaaagctgagtgcccaaacaattctagagcggcac
aactgcggcattggcatggttctgatcctgcctcagtcaagtcagctgtggcgaacgtcc
cttccgggagccaaagtactgggcgtcctgcaacggcggtcaaaggttagtggatcacct
gtccaggtgcgcaactttgtggagcaactggagaaggtggcctcgccgttcggtggtctc
ggcgatcgggaattgcccgaagagctcaagaaactgccttccaactcggatttatcagct
cctcgcgaggaatgctttgaaaacgcagctggacgtcggctcacgcgcatacccacccac
tacaaggaccccatactcatcctgggcaccgatggagtgggcaccaagctgaaaatagcg
cagcaaacgaatcgcaacacgagcgtgggtatcgatttggtggccatgtgcgtcaacgac
atcctctgcaatggagccgagccaatcagtttctcaagctactatgcctgcgggcactgg
caggagcagttggccaaggaggttcactccggggtccaagagggtgccaggcaggcgaac
agcagtttcattgactcacatagtgccgctctgccgctcctgtacgaaccccaggtctat
gatctggctggtttcgccttgggcatagcagaacacaccggaattctaccccttttggat
gaaatccagcccggagatgtgctcatcggcttaccttcgtctggcgtccacagcaacgga
tttagtttggttcacgccgttttgaagcgagtgggcttgggtctgcatgacaaggcgccc
tttagtgataagacgctgggcgaggagctgctggtgcccaccaagatctatgtcaaggca
ttgtccactctgctgtcccgcggaaaacacggcatcaaggcactagcccacatcacagga
ggaggcctgagcgagaatataccgcgagtattgcgtaaggatttggccgtgcgcctggat
gccaataagttccagcttccgcccgttttcgcctggcttgcagcggccggaaatatcagc
tccactgagctgcagcgcacatataactgcggcttggggatggttctggtggtggccccg
acggaagtcgaggacgttcttaaggagctgcgttatccgcaaagagcagctgtggtcggc
gaggtggtggcacgcaaggatccgaagaagtcgcaggtggtggtccagaactttgaggca
tcattggccaggacacagaagatgctctcgcagcgtcggaaacgagttgctgttctcatt
tcgggaacgggcagcaacctgcaagcactaattgatgcaacgcgcgactcggcacagggt
atccatgccgatgttgtgctggtaatcagcaataagactggtgttctgggtctgcagcga
gccacgcaagccggaataccttcgttggtcatctcccacaaggatttcgctagccgagag
gtctatgatgcggaacttacgcgaaatctgaaggcggctcgtgtggatttgatctgcctt
gccggcttcatgcgtgtcctgagtgctccattcgttcgagagtggcgtggacggctcgtc
aatatccatccctcgctgctgcccaagtatcctggtctgcatgtccagaagcaggccttg
gaggcgggcgaaaaggagtccggctgcacggttcacttcgtggacgagggtgtggacacg
ggagcgatcattgttcaggctgctgttcccattttgcccgatgacgacgaggattcgctg
acccaacgcatccacaaggctgagcactgggcttttccaagggcattagcaatgttggtc
aacggaacagctctcatttctccggaagtcagcagtcagtaa
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