Drosophila melanogaster (fruit fly): Dmel_CG3194
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Entry
Dmel_CG3194 CDS
T00030
Symbol
Hsepi
Name
(RefSeq) heparan sulfate C5-epimerase, isoform B
KO
K01793
heparosan-N-sulfate-glucuronate 5-epimerase [EC:
5.1.3.17
]
Organism
dme
Drosophila melanogaster (fruit fly)
Pathway
dme00534
Glycosaminoglycan biosynthesis - heparan sulfate / heparin
dme01100
Metabolic pathways
Module
dme_M00059
Glycosaminoglycan biosynthesis, heparan sulfate backbone
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
Dmel_CG3194 (Hsepi)
Enzymes [BR:
dme01000
]
5. Isomerases
5.1 Racemases and epimerases
5.1.3 Acting on carbohydrates and derivatives
5.1.3.17 heparosan-N-sulfate-glucuronate 5-epimerase
Dmel_CG3194 (Hsepi)
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Gene cluster
GFIT
Motif
Pfam:
C5-epim_C
Glce_b_sandwich
Motif
Other DBs
NCBI-GeneID:
35569
NCBI-ProteinID:
NP_001163062
FlyBase:
FBgn0033087
UniProt:
C3KGM6
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Position
2R
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AA seq
612 aa
AA seq
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MSKYLSSQRDALSAPALPVSRENREPPKFQGQREPLVFFIMRLNLKAVLLVLTVAVVVIT
LGVYMRCAAFSFSPDFVRPLDRSARQSSSGGEATALHDIECSINQEYTVHCKRDENANEV
YVPFSFLRNYFDVSGAVSTNSNEVAKFNWVHSTAKVNLPRGKYDARGVYMYFENYNVEVR
DRVKCISAAEGVPVSTQWEKRGYFYPTQIAQFALSHYSKNLTEPAPRVRVLEDGDGNQME
WSTPKTSNMTRIWHHKFNTSVVQFETAPGYEGVISIALNQTLDLLLSVDLLLVTNSSSLM
ITVQNRDTRHNYSLHYIPADLLLSVQDTNIYYGLGGSALNKWRHITRDLHIDLQKGIMGD
KRSPLKIRRSDLEVISIGFLGLGFFDNITLSTSDHLAHFYDAAEWFVHNQDPKTGGWTNP
VRRSLNGFAELRPGWISAMGQGHAISVLARAYWHSGGDERYLRAAAAGLQPYRVYSRDGG
VLAQFMDKFYWYEEYPTTPPSYVLNGFIYSLLGLYDLNSTAPGKIAREAGKLFAQGMHSL
KKMLLLFDTGSGTSYDLRHLSLGVAPNLARWDYHATHVNQLLLLATIDSDPLIAQTAERW
KGYMFGRRAKHN
NT seq
1839 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaatatctaagcagtcagagagatgccctttccgcacccgcgcttccagtaagc
agggaaaaccgggagccacctaaattccaagggcaacgcgagccactggtctttttcatc
atgcgactgaacctaaaagccgtgctgcttgtcctcacagtggctgtggtggtaatcact
ctgggcgtgtatatgcgctgcgccgccttctccttttcgccggactttgtgcgtcctctg
gaccggtccgcaaggcagtcctccagcggaggagaagctacagcgctgcacgacattgag
tgctccattaaccaggagtacaccgtgcactgcaagcgagacgagaacgccaacgaggtt
tacgttccgttttccttcctgcgtaactacttcgacgtcagtggagcagtttccaccaac
agcaatgaggtggccaagttcaactgggtgcacagcacagccaaagttaaccttcccagg
ggaaagtacgatgcgcgcggcgtctatatgtactttgagaactacaacgtggaagtgcgc
gaccgggtaaagtgcatcagtgccgcggagggcgttccagtgagcacgcaatgggagaag
cgtgggtacttttaccccacacaaattgcccagttcgcgttgtcgcactacagcaagaac
ctcacagagccggcacccagggttcgcgtgttggaggacggcgacgggaaccagatggaa
tggagtacgcccaagaccagcaacatgacccgcatctggcaccacaagtttaacaccagt
gttgtccagttcgagacggcacctggttacgaaggcgtcatcagcattgctctaaaccag
acattggatcttctgctcagcgttgatctgctcctggtaaccaatagcagtagtctcatg
attaccgttcagaatcgggacacccgtcacaactacagcctgcactacatacccgcagat
ctgctgctgagcgtgcaggatacaaacatctactacggtctgggaggctcggcactgaac
aagtggcgccacatcactcgagacctgcacattgaccttcaaaagggcatcatgggtgac
aaacgctcgccgctaaagatacggcgctccgatctggaggtaatatctattggctttctg
ggccttggcttcttcgacaatatcaccttgtccaccagtgaccatctggctcacttctac
gacgcggctgagtggttcgtccacaaccaggaccccaagacgggtggctggaccaatcct
gtgcgtcgcagcctcaacggctttgccgaattgcgtccggggtggatatcagccatgggc
cagggacacgctatttcagtgctggcacgagcctactggcactccggcggggatgaacgc
taccttcgagcggccgcagccggactgcagccttatagggtatactcgcgcgatggcggc
gttctggcgcagttcatggacaagttctactggtacgaggagtaccccaccacgccaccc
tcttatgtgctaaacggctttatctattcactgctgggtctctacgatctcaacagcact
gccccgggaaaaatcgcccgcgaggctggaaagcttttcgcgcagggcatgcactccctt
aaaaagatgctgttgctatttgacactggctccggcaccagctacgacctgcgccatctg
agcctgggcgtagctcctaatctggcgcgctgggactaccatgcaacgcacgtgaaccag
ttacttctgttagccaccatcgacagcgatccattaattgcacaaactgcggagcgctgg
aagggctatatgtttggtcgtcgggccaagcacaactga
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