Drosophila melanogaster (fruit fly): Dmel_CG4147
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Entry
Dmel_CG4147 CDS
T00030
Symbol
Hsc70-3
Name
(RefSeq) heat shock protein 70 cognate 3, isoform E
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
5.6.1.10
]
Organism
dme
Drosophila melanogaster (fruit fly)
Pathway
dme03060
Protein export
dme04141
Protein processing in endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
Dmel_CG4147 (Hsc70-3)
04141 Protein processing in endoplasmic reticulum
Dmel_CG4147 (Hsc70-3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
dme03110
]
Dmel_CG4147 (Hsc70-3)
04131 Membrane trafficking [BR:
dme04131
]
Dmel_CG4147 (Hsc70-3)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
dme04147
]
Dmel_CG4147 (Hsc70-3)
Enzymes [BR:
dme01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.10 non-chaperonin molecular chaperone ATPase
Dmel_CG4147 (Hsc70-3)
Chaperones and folding catalysts [BR:
dme03110
]
Heat shock proteins
HSP70 / DNAK
Dmel_CG4147 (Hsc70-3)
Membrane trafficking [BR:
dme04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
Dmel_CG4147 (Hsc70-3)
Autophagy
ER-phagy
ER stress-related proteins
Dmel_CG4147 (Hsc70-3)
Exosome [BR:
dme04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
Dmel_CG4147 (Hsc70-3)
Exosomal proteins of other body fluids (saliva and urine)
Dmel_CG4147 (Hsc70-3)
Exosomal proteins of colorectal cancer cells
Dmel_CG4147 (Hsc70-3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
FGGY_C
TBCA_PH
Motif
Other DBs
NCBI-GeneID:
32133
NCBI-ProteinID:
NP_001285139
FlyBase:
FBgn0001218
UniProt:
P29844
F3YDH0
LinkDB
All DBs
Position
X:complement(11801696..11807117)
Genome browser
AA seq
656 aa
AA seq
DB search
MKLCILLAVVAFVGLSLGEEKKEKDKELGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGN
RITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKV
VEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALS
GSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIV
LVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLDVN
PLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLG
KFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDR
MIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDE
SIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQGAGGAPPPEGGDDADLKDEL
NT seq
1971 nt
NT seq
+upstream
nt +downstream
nt
atgaagttatgcatattactggccgtcgtggccttcgttggcctctcgctgggcgaggag
aagaaggaaaaggacaaggagctgggcacagtgatcggcattgatttgggcaccacgtat
tcctgcgttggtgtgtacaagaacggacgcgttgagatcatcgccaacgatcagggtaac
cgcatcactccctcctacgtcgctttcaccgctgacggtgagcgtctcattggagatgcc
gccaagaatcagttgaccaccaatcccgagaacacggtcttcgatgccaagcgtctgatc
ggtcgcgaatggtccgacaccaatgtgcaacacgacatcaagttcttcccattcaaggtt
gtcgagaagaactcgaagccccacatcagcgtggacacgtcacagggcgccaaggtgttc
gcacccgaggagatctccgccatggttctgggcaagatgaaggaaaccgctgaagcttat
ctgggcaagaaggtcacccatgccgtcgttaccgtgccagcctacttcaacgatgcccag
cgtcaggccaccaaggatgctggtgttattgccggtctgcaggtgatgcgcatcatcaac
gaacccactgctgcggctattgcctacggtctggacaagaaggagggggagaagaacgtg
cttgtgttcgatttgggcggcggcaccttcgatgtctccctgctgaccatcgataacgga
gtgttcgaggtggtggccaccaacggtgatactcatttgggaggtgaggacttcgatcag
cgtgtgatggatcacttcatcaagctgtacaagaagaagaagggcaaggacattcgcaag
gacaaccgcgctgttcagaagctgcgtcgtgaggttgagaaggccaagcgtgccctgtct
ggttcccaccaggtgcgcatcgaaattgaatccttcttcgagggcgatgacttctccgag
accctgacccgtgccaagttcgaggagctcaacctggatctattccgttccaccctgaag
ccagtgcagaaggtgctcgaggatgctgacatgaacaagaaggacgtgcacgagattgtg
ctggtcggtggctccactcgtatccccaaggtgcagcagctggtcaaggacttcttcggc
ggcaaggaaccatcccgaggcatcaatcccgatgaggctgtggcctacggtgctgctgtg
caggctggcgtgctctctggcgaacaagataccgatgctattgtcctgctcgatgtgaac
ccactgaccatgggtattgagaccgtcggcggtgtgatgaccaagctgattccccgcaac
accgtcatccccaccaagaagtcgcaggtgttctccactgcctccgataaccagcacacc
gtcaccatccaggtgtacgagggcgagcgtcccatgaccaaggacaaccatctgttgggc
aagttcgatctgactggcatcccaccagcaccccgtggcattccccagattgaggtttcg
ttcgagatcgacgccaacggcatcctgcaggtcagtgccgaggacaagggtaccggtaac
aaggaaaagatcgtcatcaccaacgaccagaaccgcctgacgcccgaggatatcgatcgc
atgatccgcgatgccgagaaattcgccgatgaggacaagaagctgaaggagcgtgtggag
tcccgcaacgaactggaatcgtatgcctacagcctgaagaaccagatcggtgacaaggac
aagctgggtgccaagctgagcgacgatgagaagaacaagctggagtcggccatcgatgag
tcgatcaagtggctggaacagaatcccgatgccgatcccgaggagtacaagaagcagaag
aaggatctggaggccatcgttcagcccgtgattgctaagctgtaccagggtgctggcggt
gctcctcctccagagggcggcgatgatgccgatctcaaggacgagctgtaa
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