Drosophila melanogaster (fruit fly): Dmel_CG4943
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Entry
Dmel_CG4943 CDS
T00030
Gene name
Smurf
Definition
(RefSeq) SMAD specific E3 ubiquitin protein ligase, isoform B
KO
K04678
E3 ubiquitin ligase SMURF1/2 [EC:
2.3.2.26
]
Organism
dme
Drosophila melanogaster (fruit fly)
Pathway
dme04120
Ubiquitin mediated proteolysis
dme04144
Endocytosis
dme04341
Hedgehog signaling pathway - fly
dme04350
TGF-beta signaling pathway
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
Dmel_CG4943 (Smurf)
09130 Environmental Information Processing
09132 Signal transduction
04341 Hedgehog signaling pathway - fly
Dmel_CG4943 (Smurf)
04350 TGF-beta signaling pathway
Dmel_CG4943 (Smurf)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
Dmel_CG4943 (Smurf)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dme04131
]
Dmel_CG4943 (Smurf)
04121 Ubiquitin system [BR:
dme04121
]
Dmel_CG4943 (Smurf)
03029 Mitochondrial biogenesis [BR:
dme03029
]
Dmel_CG4943 (Smurf)
Enzymes [BR:
dme01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
Dmel_CG4943 (Smurf)
Membrane trafficking [BR:
dme04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
Dmel_CG4943 (Smurf)
Autophagy
Mitophagy
Other mitophagy associated proteins
Dmel_CG4943 (Smurf)
Ubiquitin system [BR:
dme04121
]
Ubiquitin ligases (E3)
HECT type E3
Dmel_CG4943 (Smurf)
Mitochondrial biogenesis [BR:
dme03029
]
Mitochondrial quality control factors
Mitophagy factors
Parkin-independent mechanism factors
Dmel_CG4943 (Smurf)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
36999
NCBI-ProteinID:
NP_001261061
FlyBase:
FBgn0029006
UniProt:
Q9V853
A0A0B4KFU5
LinkDB
All DBs
Position
2R
AA seq
1061 aa
AA seq
DB search
MNKLDYPRRNGTHKVRITILCARNLARKDLFRLPDPFAKVQVDGTGQVYSTEISKSSLDP
KWNAHYDLFLGIGDAITITVWNQRKIHKGSGFLGCVRIPAFNIQSLKGAGFQRLDLGKLS
PDDDELVRGQIIISLLSKDGPSSGNPLAIVGPSGDVRGPSEDDSSEDSLPEGWEERRTDN
GRVYYVNHATKSTQWDRPRQPGVVGSSHATSPQQRHNTHNGNSGDRQAPAGPTRSTTCTN
LMNNGHRSRDLSVTASDERRHSTEILSSVGKENTSPTTPVSATTTPGKKTSSSNSSSAGG
RTLEQRPTNEPATPTSSTTSASVRLHSNDNHVKTPKHQTNGHAPPESTPTSPTGQQNYVN
GNAQNGSTSGNGSGQAAQPQSASNGWTQEDAATTTSPSTTTSPPRHSQSPPTPNISPPAS
VTPSANGNVHSPNANSTPAGSGGGSRSYTAATPGQRSQRRSSRQQGEESSTRRRSSRGTR
NGGTSGGGGGGGSGQRYASAAIAAANQAARPFLDLPPGYEMRTTQQGQVYFYHIPTGVST
WHDPRIPRDFDTQHLTLDAIGPLPSGWEQRKTASGRVYFVDHNNRTTQFTDPRLSGSILQ
MIRRGTVPPTSAANAGTPAPPSATPATPSAAAAVPPQATPASNATPTTLTTTTNPPHRIV
PDLPQGLLEGADLLPKYRRDLVGKLRALRTELQTMQPQSGHCRLEVSRNEIFEESYRLIM
KMRAKDMRKRLMVKFKGEEGLDYGGVAREWLHLLSREMLNPQYGLFQYSRDDHYTLQINP
DSGVNPDHLSYFHFVGRTLGIAVFHGHCLDGGFTTPFYKQLLNKPITLGDIEGVDPDLHR
SLTWMLESNISGIIESTFSVENNSFGALVVHELKPGGASIPVTEENKREYVKLYVNYRFM
RGIEQQFLALQKGFCELIPSHLLRPFDERELELVIGGISSIDVNDWRNNTRLKHCTNETT
QVLWFWQVVESYSSEMRARLLQFVTGSSRVPLQGFRALQGSTGAVGPRLFTIHLTADVPT
QNLPKAHTCFNRIDLPPYETYQLLCDKLTQAVEETCGFAVE
NT seq
3186 nt
NT seq
+upstream
nt +downstream
nt
atgaataaattggattacccacgtcgcaatggtacacacaaagttcgaataacgatattg
tgtgctagaaacttggcccgcaaggatttatttcgtctacccgatccctttgctaaggtg
caggtggatggaactgggcaggtgtactcgacggaaataagcaaatcctctctggatcca
aaatggaatgcacattacgatttgtttttgggcattggggatgccattacgataactgtg
tggaatcagcgaaagatacacaagggcagtggattcctgggctgtgtgaggataccggcg
ttcaacatacagagcctcaaaggagctgggtttcaacgcttggatctgggaaaactgtcg
ccggatgacgatgagcttgtacgtggtcaaatcatcatttcgttgctctcgaaggacggt
cctagtagtggtaatcctctggccattgtaggacccagtggtgatgtccgtggaccgtcg
gaagatgactcctcggaagatagtttgccagagggttgggaggagcggcgtacggacaac
ggtcgagtttactatgtgaaccatgccaccaaatcgacgcagtgggatcgaccaagacag
ccaggagtagttggatccagtcacgccacttcaccacagcaacggcacaacacgcacaat
ggcaacagcggtgatcgacaagctccggctgggccaacccgctctacaacttgcacgaac
ctgatgaataacggtcatcgcagccgggacttgtctgtgacggcttcagatgaacgtaga
cactctacggaaatcctgtccagcgtgggcaaggagaacaccagccccacaacgcccgtt
tcggccacgacaacgcctggcaaaaaaacatcctcatcgaactcatcctcggcaggtggt
cgcactttggagcagcgtccgacaaacgaaccagcaacacccaccagcagtacgacatcg
gcgtcggttcgcctgcatagcaacgacaatcatgtaaaaacaccaaagcaccaaacgaat
ggccatgctccgccagagtccacgcccacatcccccacgggtcagcagaactatgtaaat
ggaaatgctcagaatggaagtaccagcggaaatggaagtggccaggcggcgcagccccag
agtgctagtaacggatggacgcaagaagatgccgcaacgactacttcaccttcaaccaca
acctctcctcccaggcatagtcaaagtccgccaactccaaatatatcgccgccagcttca
gtgacaccctctgcaaatggaaatgtgcacagtccgaatgcgaacagcacaccagccgga
agcggaggaggaagtagatcctatacagcagcaacgcccggtcaacgctctcagcgtcgg
agctcgcggcaacaaggtgaggagtcctccaccagacgacggtcttcacggggaacaaga
aatgggggcacatctggcggcggaggtggaggtggatctgggcagaggtacgcctcggca
gccattgcagctgccaatcaggcagcacgaccatttttggatctgccgcccggctatgaa
atgcgaacaacgcaacaagggcaggtatacttttatcacatacccactggtgtatccacg
tggcatgatcctcggatacccagagatttcgacacccaacatctaacgcttgacgctatc
ggaccattgccgagtggttgggaacagcgaaagacggcctccggaagggtttactttgtg
gaccacaacaaccgaaccacacagtttacggatccccggctaagtggcagtattttgcaa
atgattcgacgtggaaccgtaccaccaacatccgctgcaaatgctggaacaccagctccg
ccatcggctactcctgctaccccctcggccgcagcagcagttccaccacaggcgacgccg
gcgagcaacgcaactccaacgacgcttacaactacaacaaacccgccccatcgtattgtt
ccggatctgccacagggattgcttgaaggcgccgaccttttgcccaagtaccgccgcgat
ttggttggcaagctgcgggctctgcgcacggagctgcaaacgatgcagccgcaatccggc
cactgccgtttggaggtgtcacgcaacgagattttcgaggagagctatagactgataatg
aaaatgcgggccaaggacatgcgaaagcgtctaatggttaaatttaagggcgaggagggc
ctggactatggtggcgtagcacgcgagtggttgcatctgctttcccgagagatgttgaat
ccgcagtatggcctattccagtacagtagggatgatcactacacgctgcaaattaatcca
gactccggtgtgaatcccgatcacttgtcctattttcatttcgtgggtcgcacactaggg
attgccgtgttccacggtcactgtctggatggtgggttcactacacccttctacaagcag
ctgctgaacaagccgattacgcttggtgatattgaaggcgtggatccggacctacatcgc
agcctcacctggatgctggaaagcaacatcagcggcatcattgaatccacattcagtgta
gagaacaatagctttggtgctctggtggtgcatgaactgaagcctggcggtgcctccatt
ccagtgacggaggagaacaaacgcgagtatgtcaagctctatgtgaactatcgttttatg
cgcggcattgaacaacaatttttggctctgcagaaaggtttttgtgagcttatacccagc
catctcctaagaccgtttgatgagcgcgaattggaattggtcattggtggcatctctagc
atagatgtcaacgactggcggaacaatacgagactgaagcactgtacgaacgaaacgacg
caggtgttgtggttctggcaggtggtcgagtcctatagttctgagatgagagcccgtctg
ctgcaattcgtgacaggatcatcgcgagtgccgctgcagggcttcagagcgctacagggc
tccacgggagcggtgggaccacggctgtttactattcacctgactgccgacgtgcccacg
cagaacctgcccaaggcgcacacctgctttaaccggatcgatttgccgccctacgagacg
taccagctactttgcgacaagctgacgcaggccgttgaggagacctgtggatttgccgtg
gagtaa
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