Drosophila melanogaster (fruit fly): Dmel_CG9127
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Entry
Dmel_CG9127 CDS
T00030
Symbol
Pfas
Name
(RefSeq) phosphoribosylformylglycinamidine synthase, isoform A
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
dme
Drosophila melanogaster (fruit fly)
Pathway
dme00230
Purine metabolism
dme01100
Metabolic pathways
Module
dme_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Dmel_CG9127 (Pfas)
Enzymes [BR:
dme01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
Dmel_CG9127 (Pfas)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-GeneID:
33847
NCBI-ProteinID:
NP_477212
FlyBase:
FBgn0000052
UniProt:
P35421
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Position
2L
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AA seq
1354 aa
AA seq
DB search
MVILRYYDVQAHSAAEEESVLRRLREEDGAVVSVRMERCYHLEYSAQAEHSLALDELLVW
LVKQPLSKGQSLSRQPALQSTGSSQLLLEIGPRFNFSTPYSTNCVNIFQNLGYSEVRRME
TSTRYLVTFGEGSKAPEAARFVPLLGDRMTQCLYTEENTPKASFDEQLPERQANWHFVPV
LEEGRAALERINQELGLAFNDYDLDYYHDLFAKELGRNPTTVELFDCAQSNSEHSRHWFF
RGRMVIDGVEQPKSLIRMIMDTQAHTNPNNTIKFSDNSSAMVGFDHQTIVPSSVVAPGAV
RLQSVQSDLIFTAETHNMPTAVAPFSGATTGTGGRLRDVQGVGRGGVPIAGTAGYCVGAL
HIPGYKQPYEPLDFKYPATFAPPLQVLIEASNGASDYGNKFGEPVISGFALSYGLNSAAD
ASQRDEYVKPIMFSGGLGTMPATMREKLPPARGQLLAKIGGPVYRIGVGGGAASSVEIQG
SGDAELDFNAVQRGDAEMENKLNRVVRACLDLGEQNPILAIHDQGAGGNGNVLKELVEPG
FAGAVIFSKEFQLGDPTITALELWGAEYQENNAILCNADQRELLEKICRRERCPISFVGV
VTGDGRVTLLEKPAPKDLEQALNASNRSEVSPFDLELKYVLGDMPKRTYDLKREQTPLKE
LSLPKGLLLDEALERVLSLVAVGSKRFLTNKVDRCVGGLIAQQQCVGPLQAPLADYALTT
VSHFSHSGIATSIGTQPLKGLLDPAAMARMCVAEALSNLVFVKISELADVKCSGNWMWAA
KLPGEGARMFDACKELCQILEELHIAIDGGKDSLSMAAKVGGETIKSPGTLVISTYAPCP
DVRLKVTPDLKGPGAGSKTSLLWINLENSARLGGSALAQAYAQQGKDTPNLTRSDVLGKA
FAVTQSLLGDGLIQAGHDVSDGGLLVCVLEMAIGGLSGLRVDLSEPLAKLKNFDKSVEKL
NRPELAVLFAEECGWVVEVLDTDLERVRSTYEKAGVPNYYLGVTEGFGLDSRVVLKNGKS
ELLDQPLRVLYKKWERTSYELEKLQANPECAEAEYNSLEYRQAPQYRGPQNVQAELTLKR
SSAPVRVAVLREEGVNSEREMMACLLRANFEVHDVTMSDLLQGTASVSQYRGLIFPGGFS
YADTLGSAKGWAANILHNPRLLPQFEAFKRRQDVFSLGICNGCQLMTLIGFVGSAKSEVG
ADPDVALLHNKSQRFECRWATVKIPSNRSIMLGSMKDLVLGCWVAHGEGRFAFRDEKLIS
HLQSEQLVTLQYVDDVGKPTELYPLNPNGSPQGIAGLCSSDGRHLALMPHPERCSSMYQW
PYVPSSFEVSPTQSESPWQIMFNNAYNWCVKSNQ
NT seq
4065 nt
NT seq
+upstream
nt +downstream
nt
atggtcatccttcgctactacgatgtgcaggcccactccgcggccgaggaggagagtgtc
ctgcgtcggttgcgcgaggaagacggcgccgtggtgtccgtgcgcatggagcgctgctat
catctggagtacagcgctcaggcagagcactcactggccctggacgagctgctggtgtgg
ctggtcaagcaaccgctgagcaaaggccagagcttgtccaggcaacctgccctgcagtca
actgggtcgagtcagttgctcctggagatcgggccgcgttttaacttctccacgccgtac
tccacgaactgcgtgaacatattccagaatctcgggtactcagaggtgcgtcgcatggaa
acctccacccgctatctggttacttttggcgagggatcaaaggcgccggaggcagccagg
tttgttcctctgctcggtgaccgcatgacccagtgcttgtacaccgaggagaataccccc
aaggcgagctttgacgagcagctacctgagcgccaggccaactggcatttcgtgcccgtt
ttggaggagggtagggcggcactggagcggattaatcaggagctgggcttagccttcaac
gactacgatttggactactaccacgacttgtttgccaaggagctgggccgcaatcccacc
actgtggagctcttcgattgcgcccagagcaacagtgagcactcgcgccactggtttttc
cgcggacgtatggtgatcgacggcgtggagcagcccaagtcgctgattcgcatgatcatg
gacacgcaggcccacacgaacccgaacaacaccattaagttcagcgacaacagcagtgcc
atggtgggattcgatcaccagaccatagttccgtcctccgtggtcgctcccggcgcagtg
cgtctgcagagcgtgcagtctgacctgattttcacggcggagacccacaacatgcccact
gcagtggcgcctttcagcggagccaccaccggcactggcggacgactgcgtgatgtccag
ggcgtgggcagaggaggcgtgccgatcgccggcaccgctggctactgtgttggcgctctt
cacattccaggttacaaacagccgtacgagcctttggactttaaataccctgcgacgttt
gcgcccccacttcaggtgctcattgaggcgagcaatggcgcctccgactacggaaataag
ttcggcgagccagtgatctctggttttgccctctcctatggactgaacagtgctgccgat
gccagccagcgggatgagtacgtgaaaccgatcatgttcagcggtggcttgggcaccatg
cccgctaccatgcgcgagaagctgccgccggcacgcggtcagttgctggccaagatcggg
ggcccagtgtacaggattggagtgggtggcggcgccgcaagctctgtggagatacaagga
tccggagatgctgagctagattttaatgccgtacagcgaggagacgccgaaatggagaat
aaattgaaccgtgtggtgcgagcctgtctagacctgggcgagcaaaaccccatattagcc
atccatgaccagggggctggcggcaacggcaatgtcctcaaggagctagtggaaccaggc
tttgccggagctgttatcttctccaaggagttccaactcggcgatcccacgatcactgcc
ctcgaactgtggggtgccgagtaccaggaaaacaatgccattctttgcaacgctgatcaa
cgcgaactgctggaaaagatctgccgccgtgaacgctgtcccatcagcttcgtgggagtg
gtgaccggagatgggcgagtaacgctgctggagaagcctgcccccaaggatctggaacag
gcgttgaatgcgtccaatcgcagcgaagtctcaccgttcgacttggaacttaagtacgtt
ttgggcgacatgcccaagagaacgtacgacttgaaacgcgaacagacgccgctcaaggag
ttgagtctgccgaaaggtctccttctggacgaggccttggagagagttcttagcttggtg
gcagtcggtagcaagcgcttcctgaccaacaaggtggatcgctgcgtcggtggattgatt
gcacagcaacagtgcgtgggaccgctccaagctccactagcggactacgcgttaaccacc
gtctcccactttagtcactctggaatcgccacttcaattggtacacagccactaaaagga
ctgcttgatcccgccgcaatggccaggatgtgtgtggctgaagcgttgagtaaccttgtg
tttgtaaagatcagcgaactggctgatgtcaagtgctctggcaactggatgtgggctgca
aagctgcccggcgagggtgcccggatgttcgacgcctgcaaggagctctgtcagattctt
gaggaacttcacatcgccatcgatggcggaaaggactccctgtccatggcggctaaggtg
ggcggtgagacaataaagtccccgggtactcttgtcatctccacctatgctccctgtccg
gatgtgcggctaaaggtaacgcctgatcttaaaggacccggcgcggggtcgaagacttcc
ctgctctggataaatctggagaacagcgctcgcctaggtggatcggctctggctcaggca
tacgcgcagcagggcaaagatacgccaaacttgacaaggagtgatgtgctgggcaaagca
tttgctgtgactcaatcgttgttgggagatggacttattcaagcaggacacgatgtcagc
gacggaggattgcttgtttgcgtattggagatggccatcggaggactgagtggccttaga
gtggatctatcggagcccttggccaagctcaagaacttcgataagtctgtcgagaaactt
aatcgtcccgaactagctgttctcttcgccgaggagtgtggatgggtggtggaagtcctg
gacacagacctggaacgagttcgatctacctacgaaaaggcaggagtaccaaactactat
ttgggcgtgaccgagggattcggactggattccagagtggtactcaagaacggcaagtca
gagctgctggaccagccactccgtgtgctctacaagaaatgggagagaaccagttacgag
ctggaaaagcttcaggccaaccctgagtgcgccgaggcagagtacaatagccttgagtat
cgccaagcacctcagtataggggacctcagaatgtgcaggccgagcttactctcaagcga
tcctccgccccagttcgcgtggccgtgctccgtgaggagggtgtcaatagtgagcgcgag
atgatggcctgcctgctgagggctaacttcgaggtgcacgatgtgaccatgtcggatctt
cttcaaggcaccgcaagcgtgtcccaataccgcggactaattttcccgggcggcttcagc
tatgcggacactttgggatccgccaagggctgggcagcaaacatcctccacaatccccgc
ttgttgcctcagtttgaggctttcaagcgtcgtcaagatgtgttctccttgggcatttgc
aatggttgccagctgatgacacttataggatttgttggcagtgcaaagagcgaggtgggc
gcagatcccgacgtggccctgctccataacaaatcgcagcggttcgagtgtcgttgggcc
accgtgaagattccaagcaatcgctccatcatgctcggaagtatgaaggatctggttctt
ggctgttgggtggctcacggcgaaggtcgctttgcattccgcgacgagaagctcattagc
cacttgcagtcggaacagctggtgacattgcaatatgttgatgatgtaggcaaaccgacg
gaactgtatccacttaacccgaacggtagtcctcagggaattgctggcctttgctcgtcg
gatggacgtcacttggccctcatgccacatcccgagcgatgctcctccatgtaccagtgg
ccctatgtgccatcttcattcgaagtttcccccacacaatcggaaagtccttggcagatt
atgtttaacaacgcgtacaattggtgtgtcaagtcgaatcaatag
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