Dipodomys merriami (Merriam's kangaroo rat): 138803307
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Entry
138803307 CDS
T11079
Symbol
Prkaa2
Name
(RefSeq) 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1
KO
K07198
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:
2.7.11.31
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer04068
FoxO signaling pathway
dmer04140
Autophagy - animal
dmer04150
mTOR signaling pathway
dmer04151
PI3K-Akt signaling pathway
dmer04152
AMPK signaling pathway
dmer04211
Longevity regulating pathway
dmer04213
Longevity regulating pathway - multiple species
dmer04371
Apelin signaling pathway
dmer04530
Tight junction
dmer04710
Circadian rhythm
dmer04714
Thermogenesis
dmer04910
Insulin signaling pathway
dmer04920
Adipocytokine signaling pathway
dmer04921
Oxytocin signaling pathway
dmer04922
Glucagon signaling pathway
dmer04931
Insulin resistance
dmer04932
Non-alcoholic fatty liver disease
dmer04936
Alcoholic liver disease
dmer05410
Hypertrophic cardiomyopathy
dmer05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
138803307 (Prkaa2)
04068 FoxO signaling pathway
138803307 (Prkaa2)
04151 PI3K-Akt signaling pathway
138803307 (Prkaa2)
04152 AMPK signaling pathway
138803307 (Prkaa2)
04150 mTOR signaling pathway
138803307 (Prkaa2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
138803307 (Prkaa2)
09144 Cellular community - eukaryotes
04530 Tight junction
138803307 (Prkaa2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
138803307 (Prkaa2)
04922 Glucagon signaling pathway
138803307 (Prkaa2)
04920 Adipocytokine signaling pathway
138803307 (Prkaa2)
04921 Oxytocin signaling pathway
138803307 (Prkaa2)
09149 Aging
04211 Longevity regulating pathway
138803307 (Prkaa2)
04213 Longevity regulating pathway - multiple species
138803307 (Prkaa2)
09159 Environmental adaptation
04710 Circadian rhythm
138803307 (Prkaa2)
04714 Thermogenesis
138803307 (Prkaa2)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
138803307 (Prkaa2)
05410 Hypertrophic cardiomyopathy
138803307 (Prkaa2)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
138803307 (Prkaa2)
04932 Non-alcoholic fatty liver disease
138803307 (Prkaa2)
04931 Insulin resistance
138803307 (Prkaa2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dmer01001
]
138803307 (Prkaa2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dmer04131
]
138803307 (Prkaa2)
03029 Mitochondrial biogenesis [BR:
dmer03029
]
138803307 (Prkaa2)
Enzymes [BR:
dmer01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
138803307 (Prkaa2)
Protein kinases [BR:
dmer01001
]
Serine/threonine kinases: CAMK group
CAMKL family
138803307 (Prkaa2)
Membrane trafficking [BR:
dmer04131
]
Autophagy
Other autophagy associated proteins
Others
138803307 (Prkaa2)
Mitochondrial biogenesis [BR:
dmer03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
138803307 (Prkaa2)
Mitophagy factors
Other mitophagy factors
138803307 (Prkaa2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
AMPK_alpha_AID
AdenylateSensor
ABC1
Kinase-like
Kdo
APH
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
138803307
NCBI-ProteinID:
XP_069843241
LinkDB
All DBs
Position
Unknown
AA seq
552 aa
AA seq
DB search
MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGK
IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF
QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPTYLFPEDPSYDANVIDDEAIKEVCEKF
ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPTGSFMDDSAMHIP
PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
SGSSTPQRSCSAAGLHRPRSSFDSTTAENHSLSGSLTGSLTGSTLSSVAPRLGSHTMDFF
EMCASLITALAR
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atggccgagaagcagaagcacgacgggcgggtgaagatcgggcactacgtgctgggggac
acgctgggcgtcggcaccttcggcaaagtgaagattggagaacatcagttgacaggccat
aaagttgcagttaagattttaaatagacagaaaattcgaagtttggatgttgttggaaaa
ataaagcgagaaatccaaaacttaaaactctttcgtcatcctcatattatcaaactatac
caggtgatcagcacgccaacagactttttcatggtgatggaatacgtatctggtggtgaa
ttatttgactacatctgtaaacatggacgggttgaggaaatggaagccaggcggctcttt
caacagattctgtctgctgtagactattgtcataggcacatggttgtacaccgagacctg
aagccagagaatgtgctgttggatgcacatatgaatgccaagatagctgattttggactg
tctaatatgatgtcagatggtgagttcctacgaacgagttgtggatctccaaattacgca
gcccctgaagtaatctctggcagattgtatgcaggtcctgaggttgatatctggagctgt
ggtgtgatcttgtatgctcttctttgtggcaccctcccatttgatgatgagcatgtgcct
acattgtttaagaagatccgaggaggtgtgttttatattccagagtatctcaaccgctct
gtggccactctcctgatgcatatgctacaggttgaccccctgaaacgtgcaactatcaaa
gacataagagagcatgaatggtttaaacaagatttgcccacttacctatttcctgaagac
ccctcttacgatgctaatgtcattgatgatgaggctataaaagaagtgtgtgaaaagttt
gaatgtacagaatcagaagtaatgaacagtctatatagcggtgaccctcaagaccagctt
gctgtggcctaccatcttatcattgacaatcggagaatcatgaaccaagccagtgaattc
tacctggcctctagtcctccaactggctcctttatggatgacagtgccatgcatattccc
ccaggcctgaagcctcatccagaaagaatgccacctctaatagcagacagccccaaagca
cggtgtcccctggatgctctcaatacaacaaagcccaaatccttagctgtgaaaaaagcc
aagtggcaccttgggatccgaagtcagagcaagccatatgacatcatggctgaagtttac
cgagctatgaaacagctggattttgaatggaaggtagtgaatgcataccatcttcgagta
agaaggaaaaatccagtgactggcaattatgtgaaaatgagcttacagctttacctggtc
gacaaccggagttatcttttggactttaaaagcattgatgatgaggtggtggagcagagg
tctggttcctctacacctcagcgttcctgttccgctgccggcctacacagaccaagatcc
agctttgattccacaactgcggagaaccattctctttctggctcgctcactggctccttg
actggaagcactttgtcctccgttgcccctcgcctgggcagtcacaccatggactttttt
gaaatgtgtgccagtttgatcactgcattagcccgctga
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