Dipodomys merriami (Merriam's kangaroo rat): 138826780
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Entry
138826780 CDS
T11079
Symbol
Pdha2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer00010
Glycolysis / Gluconeogenesis
dmer00020
Citrate cycle (TCA cycle)
dmer00620
Pyruvate metabolism
dmer00785
Lipoic acid metabolism
dmer01100
Metabolic pathways
dmer01200
Carbon metabolism
dmer01210
2-Oxocarboxylic acid metabolism
dmer04066
HIF-1 signaling pathway
dmer04922
Glucagon signaling pathway
dmer05230
Central carbon metabolism in cancer
dmer05415
Diabetic cardiomyopathy
Module
dmer_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
138826780 (Pdha2)
00020 Citrate cycle (TCA cycle)
138826780 (Pdha2)
00620 Pyruvate metabolism
138826780 (Pdha2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
138826780 (Pdha2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
138826780 (Pdha2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
138826780 (Pdha2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
138826780 (Pdha2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
138826780 (Pdha2)
Enzymes [BR:
dmer01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
138826780 (Pdha2)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
138826780
NCBI-ProteinID:
XP_069878128
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MKKMLASVVSRVLGATQKPPLRVLLTSCNYSKDATIEIKSCDLYRLDGGPASSTLLTRDD
GLKYYRAMQIVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGIEAAIKPTDNVITSYRA
HGICYTRGLSVKSILAELTGRRGGCAKGKGGSMHMYAKHFFGGNGIVGAQVPLGAGIALA
CKYLGKRDICLAMYGDGAANQGQIAEAYNMAALWKLPCVFICENNRYAMGTAVERAAAST
DYYKRGNFIPGLKVNGMDVLCVREATRFAADHCRAGKGPIVMELQTYRYHGHSMSDPGVS
YRTREEIQTMRSKSDPIMLLQEKMISHKLSSVEELKEIDVEVRKEIEEAAQFATTDPEPS
LDELGHHLYHSNPPFDVRGANQWIKYKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaagatgctggcttctgtggtctcccgcgtgttgggggccacccagaagccccct
ctcagagtactgctgacctcctgcaactattccaaggatgctaccattgaaattaagagc
tgcgatctttaccggctggacgggggccccgcgtcctccaccttgctcacccgggacgac
gggctcaagtactaccgggccatgcagatcgttcgccggatggaactgaaggcggaccag
ctctacaaacagaaatttatccgtggcttctgccacctgtgcgacggccaggaagcttgc
tgcgtggggatcgaggcggccatcaagcccacggataacgtgatcacctcctaccgggcg
cacggcatctgctacacgcgcggactctcggtcaagtcgatcctggcggagctgacgggg
cgcaggggaggatgcgccaaaggcaagggcggctccatgcacatgtacgccaagcacttc
ttcgggggcaacggcatcgtgggcgcgcaggtgcccctgggcgcggggatcgccctggcc
tgcaagtacctggggaaacgggacatctgcctggccatgtacggcgacggagctgccaac
cagggccagatcgccgaggcctacaacatggcagcgctgtggaagctgccgtgcgtgttc
atctgcgagaacaaccgctacgccatgggcacggcggtggagagggcggcggccagcacc
gattactacaagcggggcaacttcatcccgggcctcaaggtgaacggcatggatgtgctg
tgcgtgcgcgaggccaccaggttcgcggcggatcactgccgggccgggaagggccccatc
gtgatggagctgcagacctaccggtaccacgggcacagcatgagcgacccgggcgtgagc
taccgcacgcgcgaggagatccagaccatgaggagcaagagcgaccccatcatgctgctc
caggagaagatgatcagccacaagctcagcagcgtggaagagctcaaggagatcgacgtg
gaggtgaggaaggagatcgaggaggccgcccagttcgccaccaccgaccccgagcccagc
ctggacgagctgggccatcacctctaccacagcaacccgcccttcgacgtccggggggcc
aaccagtggatcaagtacaaatccatcagttaa
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