Dipodomys merriami (Merriam's kangaroo rat): 138831043
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Entry
138831043 CDS
T11079
Symbol
Top2a
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
138831043 (Top2a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
dmer03032
]
138831043 (Top2a)
03036 Chromosome and associated proteins [BR:
dmer03036
]
138831043 (Top2a)
Enzymes [BR:
dmer01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
138831043 (Top2a)
DNA replication proteins [BR:
dmer03032
]
Eukaryotic type
DNA Topoisomerases
138831043 (Top2a)
Chromosome and associated proteins [BR:
dmer03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
138831043 (Top2a)
Centrosome formation proteins
Centriole proteins
138831043 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
138831043
NCBI-ProteinID:
XP_069884193
LinkDB
All DBs
Position
Unknown
AA seq
1524 aa
AA seq
DB search
MEVSPLQPLSENMQMNKKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQHL
WVYDEEIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN
GKGIPVVEHKVEKMYVPALIFGHLLTSSNYDDNEKKVTGGRNGYGAKLCNIFSTKFTVET
ASREYKKMFKQTWMNNMGKAGEMELKPFNGEDYTCITFQPDLSKFKMQNLDKDIVALMVR
RAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCL
TMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMW
IFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQV
QLNKKCSAVKHNRIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKY
GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD
QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSS
TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDR
KEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDG
LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL
NLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEWY
IPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIEE
LASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYH
TDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRD
FFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRG
YDSDPVKAWKEAQQKVPDEEENEESDNEKSESVPDSGPSFNYLLDMPLWYLTKEKKDELC
KQRNEKEQELDTLKKKSPSDLWKEDLAAFIEELEVVEAKEKQDEQIGLPGKGGKAKGKKT
QMMEVLPSPQGKRVIPQVTVEMKAEAEKKIKRKIKSENTEAKEDGMEIESLKERLEKKLK
REPGAKAKKQTTLPFKPVKKGKKKNPWSDSESDMSSTESNFDVPPREMEPRRAATKSKFT
VDLDSDEDFSDFDEKIEDEDFVPSDASPPKTKAPPKHTEKELKPQKSATSVVNLDDAEEN
VAPSSSLPSADLPAKIEILTQPSKKNVTVKKTATKSQSSTAVAGTKKRAAPKKTKTDPAL
NSDNSQKPDPAKNKTRRKRKPSTSDDSDSNFEKIISKAATSKKPKGETDEFLLDFDSAVA
PRAKSVRAKKPIKYLEESDEDDLF
NT seq
4575 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcgccgctgcagcctttaagtgaaaatatgcaaatgaacaaaaagaaaaat
gaagatgctaagaaaagactgtctattgaaaggatctatcaaaagaaaacacaattggaa
catattttgctccgcccagacacctacattggatctgtggaattagtgacccagcatttg
tgggtttatgatgaagaaattggcattaactatagagaagtcacttttgttcctggtttg
tacaaaatctttgatgagattctagttaatgctgccgataataagcaaagagaccccaaa
atgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaataat
ggaaaaggaattcctgttgttgaacacaaagttgaaaagatgtatgttcctgctctcata
tttggacatctcttaacttccagtaactatgacgataatgaaaagaaagtaacaggtggt
cgaaatggctatggagccaaattgtgtaacatattcagtacgaaatttactgtggaaaca
gccagtagagagtacaagaaaatgttcaaacagacatggatgaataacatggggaaagct
ggtgaaatggagctcaagccctttaatggagaagattatacatgcatcaccttccagcct
gatttatccaagttcaaaatgcaaaatctagacaaagatattgttgcactaatggttaga
agagcatatgatattgccggatcaactaaagatgtcaaagtctttcttaatggaaataag
cttccagtgaaaggattccgtagctatgtggatatgtatctgaaggataagttagatgaa
actggcaacccattgaaagtaatacatgaacaagtaaaccacagatgggaagtgtgctta
acaatgagtgaaaaaggatttcagcaaattagctttgtcaatagcattgctacttccaag
ggtggcagacatgttgactatgtagctgatcagattgtgagtaaacttgttgatgtagtg
aagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatgtgg
atttttgtgaatgccttaattgaaaacccaacttttgactctcagacaaaagaaaacatg
actttacaagccaagagctttgggtcaacatgtcaattaagtgaaaaattcatcaaagcg
gcaactggctgtggtattgtagaaagcatactaaattgggtgaagtttaaggcccaagtc
cagttaaacaagaagtgttcagctgtaaaacataacagaatcaaaggaattccaaaactt
gatgatgccaatgatgcagggagccgaaactctactgagtgtacacttatcctgactgaa
ggagactcagccaaaactttggctgtatcaggccttggtgtagttgggagagacaaatac
ggggttttccctctcagaggaaaaatactcaatgtccgagaagcttctcataaacagatc
atggaaaatgcagaaattaacaatatcatcaagattgttggtcttcagtataaaaaaaac
tatgaagatgaagattcattgaagactcttcgttatggaaagataatgattatgacagat
caggaccaagatggttcccatatcaaaggtttgctaattaattttattcatcacaactgg
ccctcccttctacgacatcgttttctggaggaatttatcactcccattgtgaaggtgtct
aaaaacaagcaagaaatggccttctacagccttcctgaatttgaagaatggaaaagttct
actccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggcaccagcacatca
aaagaagctaaggaatactttgcagatatgaaaagacatcgaatccaattcaaatattct
ggacctgaagatgatgctgcaatcagcctggcttttagcaagaaacagatagatgatcga
aaggaatggctaactaattttatggaggatagaagacaacggaagttacttggccttcct
gaggattatttatatggacaaactaccacttatctgacgtacaatgacttcataaacaag
gaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtagatggt
ttgaaaccaggtcagagaaaagttttgtttacttgtttcaaacggaatgacaaacgagag
gtaaaggttgcccagttagctgggtcagtggcagaaatgtcctcttatcatcatggtgag
atgtcattaatgatgaccattatcaatttggctcagaattttgtgggtagcaataatttg
aacctattgcagcccattggtcagttcggtaccaggctgcacggtggcaaagactctgct
agccctcgatacatctttacaatgctcagccctttggctcggttgttatttccaccaaaa
gatgaccacacactaaagttcttatatgatgacaatcaacgtgttgaacctgaatggtac
atacctattatacctatggtgctaataaatggtgctgaaggcatcggaactgggtggtcc
tgcaaaattcccaactttgatgttcgtgaagttgtaaataacatccggcgtttgatggat
ggagaagaacctttgccaatgctgccaagttacaagaacttcaagggtactattgaagag
ctggcttcaaatcaatatgtaattagtggtgaagtagctattcttaattccaccactatt
gaaatctcagagcttcctatcagaacatggacccagacatacaaagaacaggttctagaa
cccatgttgaatggcactgagaagacaccccctctcatcacagactatagggaatatcat
acagatactacagtgaagtttgttgtaaagatgactgaagaaaaactggcagaagcagag
agagttggattacacaaagtctttaaactccaaactagtctcacctgcaattctatggta
ctttttgaccatgtagggtgtttaaagaaatatgacacagtgttggatattctaagagac
ttctttgaactcaggctcaaatattatggattaagaaaagaatggcttctaggaatgctt
ggtgccgaatctgctaaactgaacaatcaggctcgctttatcttagaaaaaatagatgga
aaaattgtcattgaaaacaagcctaagaaagaacttattaaagttctgatccagagggga
tatgattcagatcctgtgaaagcctggaaagaagcccaacaaaaggttccagatgaggaa
gaaaatgaagaaagtgacaatgaaaagagtgaatctgtaccagattcagggccatccttc
aactaccttcttgatatgcccctttggtatctaaccaaggaaaaaaaggatgaactatgt
aaacaaagaaatgaaaaggagcaagaactggatacattaaagaaaaagagtccatcagat
ttatggaaagaagacttagctgcatttattgaagaattagaggttgttgaagccaaggaa
aaacaagatgaacaaatagggcttcctggaaaaggagggaaagccaaggggaagaaaaca
caaatgatggaagttttgccttctccacaaggaaaaagagtcattccccaagtgaccgta
gaaatgaaagcagaagcagaaaagaaaattaaaaggaagattaagagtgaaaacactgag
gctaaggaggatgggatggaaatagaaagcctaaaagaaagattggagaagaaactgaaa
agagaaccaggtgccaaggcaaagaaacaaactacattgccatttaaacctgtcaaaaaa
ggaaagaagaaaaacccctggtcagattcagaatcagatatgagtagtactgaaagtaat
tttgatgttcctccacgagaaatggagccacggagagctgcaacaaaatccaaattcaca
gtggatttggattcagatgaagatttttcagattttgatgaaaaaattgaagatgaagat
tttgtcccatcggatgctagtccacctaagaccaaagctcccccaaaacatactgaaaaa
gaactgaagccacagaaaagtgcaacgtcagtagttaacttggatgatgctgaagaaaat
gtagccccttcttcaagccttccatctgctgacttaccagctaaaattgaaattctaact
caaccttctaaaaagaatgtgacagtgaagaagacagcaacaaaaagtcagtcttccacc
gctgttgctggtaccaaaaaaagggcagctcccaaaaaaaccaaaacagatccagcctta
aattctgataactctcaaaagcctgaccctgccaagaacaagactcgccgcaaaaggaaa
ccatccacttctgatgattctgactctaattttgagaaaatcatttctaaagcagccaca
agcaagaaacccaaaggggagaccgatgagttccttctggactttgactcagctgtggct
cctcgggcaaagtctgtacgagccaagaaacctatcaagtacctcgaagagtcagatgaa
gatgacctgttttaa
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integrated database retrieval system
