Dipodomys merriami (Merriam's kangaroo rat): 138832496
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Entry
138832496 CDS
T11079
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer00230
Purine metabolism
dmer00670
One carbon pool by folate
dmer01100
Metabolic pathways
dmer01523
Antifolate resistance
Module
dmer_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
138832496 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
138832496 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
138832496 (Gart)
Enzymes [BR:
dmer01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
138832496 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
138832496 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
138832496 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_4
ATP-grasp_3
Dala_Dala_lig_C
RimK
LUD_dom
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
138832496
NCBI-ProteinID:
XP_069886704
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MTARVLVIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSGKISNTAIPVSDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGDLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFTKLEEACSFIMNADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
GAAGETIVIEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVPMDLLLEIKNTVLQRVVEGMQQEGTPYTGILYAGIMLTKGGLKVLEFNCRFGDPECQV
ILPLLQSDLYEVIQSTLDGRLSASLPIWLESHSAITVVMASKGYPGAYTKGTEITGFSEA
QALGLEVFHAGTSLKDGKVVTSGGRVLTVTAIRENLLLALEEAKKGLAVIKFEGAVYRRD
IGFRAIAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDVNTTEAVVAGVAKACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLDRITEGDVVVGIASSGLHSNGFSLVRKIVEKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPIIRSGHVKAFAHITGGGLLENIPRVLPPKFGVELDARSWRIPRIFSWLQHEG
QLSEEEMARTFNCGVGAALVVSKNQTEQILTAIHQRQEEAWVIGNVVACPEGSPQVKVKN
LIETMNINGSLLVNGSRKNHLPTQPKKARVAVLISGTGSNLQALIDSTLDPKSSAHIVVV
ISNKAQVAGLSKAERAGIPTKVINHKLYKSRVDFDNAVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGANAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTIETLSERVKLAEHKIFPAALQLVASGTVQLGKNGKICWVQEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atgacagcccgagtacttgtaattggaagtggcggaagggagcatacattggcctggaaa
cttgcacagtctcatcatgtcaaacaagtgttggttgccccaggaaatgcaggcactgcc
tgctctggaaagatttcaaatactgctatccccgtcagtgatcacactgcccttgctcag
ttctgcaaagatgagaaaattgagtttgtagttgttggaccagaggcacctctggctgct
ggaattgttggagacctgacctctgcaggagtacgatgcttcggccccacagcagaagca
gctcagttggagtccagcaaaagatttgccaaagagttcatggaccgacatgggatccca
actgcacgatggagagctttcaccaaacttgaagaggcctgcagcttcattatgaatgca
gacttccctgcattggtggtgaaagccagtggtcttgcagctggaaagggggtgattgtt
gcaaagagcaaagaagaggcctgcaaggctgtacaagagattatgcaggaaaaggctttt
ggagcagctggagaaacaatcgtcattgaagaacttcttgaaggagaagaagtgtcttgt
ctgtgtttcactgatgggaagacagtggcccccatgcccccggcacaagaccacaagcga
ttactggaaggagatcagggccccaacacaggggggatgggagcctattgtccagcacct
caggttcctatggatttgttactggaaattaagaacactgttcttcagagggtggtagaa
ggcatgcagcaagagggtacaccatatacaggaattctctatgctggcataatgctgacc
aagggcggcctgaaggttctagaatttaattgccgttttggtgatccagagtgccaggta
atcctcccacttcttcaaagtgatctttatgaagtgattcagtccaccctagatggccga
ctgagtgcatctctacccatttggctggaaagccactctgccataacggttgtgatggca
agtaaaggttatcctggagcctacacgaagggtacagagataacagggttttctgaagct
caagccttgggactagaggtgttccatgctggcacttctcttaaagatggcaaagtggta
accagtgggggcagagtccttacagtgacagctatccgggagaatctcctactggccctg
gaagaagccaagaagggacttgctgtgataaagtttgagggagcagtttatagaagggac
atcggctttcgggccatagctttcctccaacagcccaggggcctgacatacaaggaatcg
ggggtagacattgcagctggaaatatgctggttaagaaaattaaacctttagcaaaagcc
acctccagaccaggctgtgatgttgaccttggggggtttgctggtctctttgatttgaaa
gcagcgggtttcaaagatcctcttctggcctctggaacagatggtgttgggactaaactg
aagattgcccagctgtgcaataaacacgataccattggtcaagatttggttgccatgtgt
gtaaatgacattctggctcaaggagcagagcctctcttcttccttgattacttttcctgt
ggaaaacttgatgtcaatacaactgaagctgttgttgctggagtggctaaagcttgcaga
caagctggatgtgctcttcttggaggagaaacagcagaaatgcctgacatgtatcctcca
ggcgagtatgatctggctggttttgctgttggtgccatggagcgggatcagaaactcccc
cacctagacaggatcactgaaggcgatgttgttgttggaatcgcctcatctggtcttcac
agcaatggctttagccttgtgaggaaaattgtggagaaatcttccctccagtactcctct
ccagcacctgatggttgtggtgaccagactctaggggatctgctcctgactccaactaga
atctacagccattcactgttacccatcatccgttcaggacatgtcaaagcctttgctcat
attactggtggaggactgctagaaaacattcccagagtactgcctccgaaattcggggta
gaattggatgcccgtagctggaggatccctaggatcttctcatggttacagcatgaagga
cagctctcagaagaagagatggccagaacctttaactgtggagttggagctgctcttgtg
gtgtcaaagaaccaaacagaacaaattctgactgcgattcatcagcgtcaggaagaagcc
tgggtgatcggcaatgtggtcgcatgtcctgaaggttcccctcaagtgaaagtcaagaat
cttattgaaaccatgaacataaatgggtcattgttggtgaatggctctcggaaaaatcat
ctccccacccaaccaaagaaggcaagagtggctgtcctgatatctggaacaggatcgaac
ctccaagcactcatagacagtactctggatccaaagagctcggcacacattgttgttgta
atctccaacaaagcccaagtggctgggttgagcaaggcagagagagctggtattcccacc
aaagtaataaatcataaattatacaaaagtcgtgtagattttgacaatgcagttgaccaa
gtccttgaagagttttccacagacatagtctgtcttgcaggattcatgagaattctctct
ggcccgtttgtcagaaaatgggatggaaaaatgctgaacatccacccatctttgctccct
tcatttaagggtgcaaatgctcatgaacaagttctggaagctggagtcacaattactggg
tgcacagtacactttgtagctgaagatgtagatgctggacagatcattttacaagaagct
gttccagtgaagaggggtgacactattgaaactttgtctgaaagagtaaaattagcagaa
cacaaaatatttcctgcagccctccagctggtggccagcggaactgtacaacttggaaaa
aatggcaagatctgctgggtccaagaggaatga
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