Dipodomys merriami (Merriam's kangaroo rat): 138840451
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Entry
138840451 CDS
T11079
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer00010
Glycolysis / Gluconeogenesis
dmer00020
Citrate cycle (TCA cycle)
dmer00620
Pyruvate metabolism
dmer00785
Lipoic acid metabolism
dmer01100
Metabolic pathways
dmer01200
Carbon metabolism
dmer01210
2-Oxocarboxylic acid metabolism
dmer04066
HIF-1 signaling pathway
dmer04922
Glucagon signaling pathway
dmer05230
Central carbon metabolism in cancer
dmer05415
Diabetic cardiomyopathy
Module
dmer_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
138840451 (Pdha1)
00020 Citrate cycle (TCA cycle)
138840451 (Pdha1)
00620 Pyruvate metabolism
138840451 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
138840451 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
138840451 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
138840451 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
138840451 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
138840451 (Pdha1)
Enzymes [BR:
dmer01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
138840451 (Pdha1)
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Ortholog
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
138840451
NCBI-ProteinID:
XP_069896875
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLLGVAQKPATRVLVASRNFANDATFEIKKCDLHRLDEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgccgtttcccgcgtgttgctgggcgttgcccagaagccggca
accagagtgctagtggcatcgcgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgaccttcaccgactggatgaaggccctcccgttacaactgtgctcaccagagaggat
gggctcaaatactataggatgatgcagactgtgcgcagaatggagttaaaagctgatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtggggctcgaggccggtataaaccccacagaccatctcatcacagcctaccgggct
catggcttcaccttcactcggggtctttctgttcgtgaaattctcgcagagctaacagga
cgaagaggaggttgtgctaaagggaaaggaggatctatgcacatgtatgccaagaacttc
tacgggggcaatggcatcgttggagctcaggtacccctgggagctgggattgctctggcc
tgtaagtataatggaaaagatgaagtctgtttgacactatatggtgatggtgctgctaat
cagggtcagatatttgaagcttacaatatggcagcattatggaaattaccgtgcattttc
atctgtgagaataaccgctatggaatgggaacatctgttgagagagcagcagccagtact
gattactacaagagaggagactttatccctgggctgagggtagatggaatggatatcttg
tgtgtccgagaggccacgaagtttgcagctgcctattgtagatctgggaagggacctatc
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgaccctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaatagcaatctggccagtgttgaagaattgaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgccacagctgatcctgagccacca
ttggaagagctcggctatcacatctacagcagcgatccaccatttgaagtgcgtggtgcc
aaccagtggatcaagtttaagtcagtcagttaa
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