Dipodomys merriami (Merriam's kangaroo rat): 138841723
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Entry
138841723 CDS
T11079
Name
(RefSeq) mitogen-activated protein kinase 3
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer01521
EGFR tyrosine kinase inhibitor resistance
dmer01522
Endocrine resistance
dmer01524
Platinum drug resistance
dmer04010
MAPK signaling pathway
dmer04012
ErbB signaling pathway
dmer04014
Ras signaling pathway
dmer04015
Rap1 signaling pathway
dmer04022
cGMP-PKG signaling pathway
dmer04024
cAMP signaling pathway
dmer04062
Chemokine signaling pathway
dmer04066
HIF-1 signaling pathway
dmer04068
FoxO signaling pathway
dmer04071
Sphingolipid signaling pathway
dmer04072
Phospholipase D signaling pathway
dmer04114
Oocyte meiosis
dmer04140
Autophagy - animal
dmer04148
Efferocytosis
dmer04150
mTOR signaling pathway
dmer04151
PI3K-Akt signaling pathway
dmer04210
Apoptosis
dmer04218
Cellular senescence
dmer04261
Adrenergic signaling in cardiomyocytes
dmer04270
Vascular smooth muscle contraction
dmer04350
TGF-beta signaling pathway
dmer04360
Axon guidance
dmer04370
VEGF signaling pathway
dmer04371
Apelin signaling pathway
dmer04380
Osteoclast differentiation
dmer04510
Focal adhesion
dmer04520
Adherens junction
dmer04540
Gap junction
dmer04550
Signaling pathways regulating pluripotency of stem cells
dmer04611
Platelet activation
dmer04613
Neutrophil extracellular trap formation
dmer04620
Toll-like receptor signaling pathway
dmer04621
NOD-like receptor signaling pathway
dmer04625
C-type lectin receptor signaling pathway
dmer04650
Natural killer cell mediated cytotoxicity
dmer04657
IL-17 signaling pathway
dmer04658
Th1 and Th2 cell differentiation
dmer04659
Th17 cell differentiation
dmer04660
T cell receptor signaling pathway
dmer04662
B cell receptor signaling pathway
dmer04664
Fc epsilon RI signaling pathway
dmer04666
Fc gamma R-mediated phagocytosis
dmer04668
TNF signaling pathway
dmer04713
Circadian entrainment
dmer04720
Long-term potentiation
dmer04722
Neurotrophin signaling pathway
dmer04723
Retrograde endocannabinoid signaling
dmer04724
Glutamatergic synapse
dmer04725
Cholinergic synapse
dmer04726
Serotonergic synapse
dmer04730
Long-term depression
dmer04810
Regulation of actin cytoskeleton
dmer04910
Insulin signaling pathway
dmer04912
GnRH signaling pathway
dmer04914
Progesterone-mediated oocyte maturation
dmer04915
Estrogen signaling pathway
dmer04916
Melanogenesis
dmer04917
Prolactin signaling pathway
dmer04919
Thyroid hormone signaling pathway
dmer04921
Oxytocin signaling pathway
dmer04926
Relaxin signaling pathway
dmer04928
Parathyroid hormone synthesis, secretion and action
dmer04929
GnRH secretion
dmer04930
Type II diabetes mellitus
dmer04933
AGE-RAGE signaling pathway in diabetic complications
dmer04934
Cushing syndrome
dmer04935
Growth hormone synthesis, secretion and action
dmer04960
Aldosterone-regulated sodium reabsorption
dmer05010
Alzheimer disease
dmer05020
Prion disease
dmer05022
Pathways of neurodegeneration - multiple diseases
dmer05034
Alcoholism
dmer05132
Salmonella infection
dmer05133
Pertussis
dmer05135
Yersinia infection
dmer05140
Leishmaniasis
dmer05142
Chagas disease
dmer05145
Toxoplasmosis
dmer05152
Tuberculosis
dmer05160
Hepatitis C
dmer05161
Hepatitis B
dmer05163
Human cytomegalovirus infection
dmer05164
Influenza A
dmer05165
Human papillomavirus infection
dmer05166
Human T-cell leukemia virus 1 infection
dmer05167
Kaposi sarcoma-associated herpesvirus infection
dmer05170
Human immunodeficiency virus 1 infection
dmer05171
Coronavirus disease - COVID-19
dmer05200
Pathways in cancer
dmer05203
Viral carcinogenesis
dmer05205
Proteoglycans in cancer
dmer05206
MicroRNAs in cancer
dmer05207
Chemical carcinogenesis - receptor activation
dmer05208
Chemical carcinogenesis - reactive oxygen species
dmer05210
Colorectal cancer
dmer05211
Renal cell carcinoma
dmer05212
Pancreatic cancer
dmer05213
Endometrial cancer
dmer05214
Glioma
dmer05215
Prostate cancer
dmer05216
Thyroid cancer
dmer05218
Melanoma
dmer05219
Bladder cancer
dmer05220
Chronic myeloid leukemia
dmer05221
Acute myeloid leukemia
dmer05223
Non-small cell lung cancer
dmer05224
Breast cancer
dmer05225
Hepatocellular carcinoma
dmer05226
Gastric cancer
dmer05230
Central carbon metabolism in cancer
dmer05231
Choline metabolism in cancer
dmer05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
dmer05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
138841723
04012 ErbB signaling pathway
138841723
04014 Ras signaling pathway
138841723
04015 Rap1 signaling pathway
138841723
04350 TGF-beta signaling pathway
138841723
04370 VEGF signaling pathway
138841723
04371 Apelin signaling pathway
138841723
04668 TNF signaling pathway
138841723
04066 HIF-1 signaling pathway
138841723
04068 FoxO signaling pathway
138841723
04072 Phospholipase D signaling pathway
138841723
04071 Sphingolipid signaling pathway
138841723
04024 cAMP signaling pathway
138841723
04022 cGMP-PKG signaling pathway
138841723
04151 PI3K-Akt signaling pathway
138841723
04150 mTOR signaling pathway
138841723
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
138841723
04148 Efferocytosis
138841723
09143 Cell growth and death
04114 Oocyte meiosis
138841723
04210 Apoptosis
138841723
04218 Cellular senescence
138841723
09144 Cellular community - eukaryotes
04510 Focal adhesion
138841723
04520 Adherens junction
138841723
04540 Gap junction
138841723
04550 Signaling pathways regulating pluripotency of stem cells
138841723
09142 Cell motility
04810 Regulation of actin cytoskeleton
138841723
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
138841723
04613 Neutrophil extracellular trap formation
138841723
04620 Toll-like receptor signaling pathway
138841723
04621 NOD-like receptor signaling pathway
138841723
04625 C-type lectin receptor signaling pathway
138841723
04650 Natural killer cell mediated cytotoxicity
138841723
04660 T cell receptor signaling pathway
138841723
04658 Th1 and Th2 cell differentiation
138841723
04659 Th17 cell differentiation
138841723
04657 IL-17 signaling pathway
138841723
04662 B cell receptor signaling pathway
138841723
04664 Fc epsilon RI signaling pathway
138841723
04666 Fc gamma R-mediated phagocytosis
138841723
04062 Chemokine signaling pathway
138841723
09152 Endocrine system
04910 Insulin signaling pathway
138841723
04929 GnRH secretion
138841723
04912 GnRH signaling pathway
138841723
04915 Estrogen signaling pathway
138841723
04914 Progesterone-mediated oocyte maturation
138841723
04917 Prolactin signaling pathway
138841723
04921 Oxytocin signaling pathway
138841723
04926 Relaxin signaling pathway
138841723
04935 Growth hormone synthesis, secretion and action
138841723
04919 Thyroid hormone signaling pathway
138841723
04928 Parathyroid hormone synthesis, secretion and action
138841723
04916 Melanogenesis
138841723
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
138841723
04270 Vascular smooth muscle contraction
138841723
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
138841723
09156 Nervous system
04724 Glutamatergic synapse
138841723
04725 Cholinergic synapse
138841723
04726 Serotonergic synapse
138841723
04720 Long-term potentiation
138841723
04730 Long-term depression
138841723
04723 Retrograde endocannabinoid signaling
138841723
04722 Neurotrophin signaling pathway
138841723
09158 Development and regeneration
04360 Axon guidance
138841723
04380 Osteoclast differentiation
138841723
09159 Environmental adaptation
04713 Circadian entrainment
138841723
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
138841723
05206 MicroRNAs in cancer
138841723
05205 Proteoglycans in cancer
138841723
05207 Chemical carcinogenesis - receptor activation
138841723
05208 Chemical carcinogenesis - reactive oxygen species
138841723
05203 Viral carcinogenesis
138841723
05230 Central carbon metabolism in cancer
138841723
05231 Choline metabolism in cancer
138841723
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
138841723
09162 Cancer: specific types
05210 Colorectal cancer
138841723
05212 Pancreatic cancer
138841723
05225 Hepatocellular carcinoma
138841723
05226 Gastric cancer
138841723
05214 Glioma
138841723
05216 Thyroid cancer
138841723
05221 Acute myeloid leukemia
138841723
05220 Chronic myeloid leukemia
138841723
05218 Melanoma
138841723
05211 Renal cell carcinoma
138841723
05219 Bladder cancer
138841723
05215 Prostate cancer
138841723
05213 Endometrial cancer
138841723
05224 Breast cancer
138841723
05223 Non-small cell lung cancer
138841723
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
138841723
05170 Human immunodeficiency virus 1 infection
138841723
05161 Hepatitis B
138841723
05160 Hepatitis C
138841723
05171 Coronavirus disease - COVID-19
138841723
05164 Influenza A
138841723
05163 Human cytomegalovirus infection
138841723
05167 Kaposi sarcoma-associated herpesvirus infection
138841723
05165 Human papillomavirus infection
138841723
09171 Infectious disease: bacterial
05132 Salmonella infection
138841723
05135 Yersinia infection
138841723
05133 Pertussis
138841723
05152 Tuberculosis
138841723
09174 Infectious disease: parasitic
05145 Toxoplasmosis
138841723
05140 Leishmaniasis
138841723
05142 Chagas disease
138841723
09164 Neurodegenerative disease
05010 Alzheimer disease
138841723
05020 Prion disease
138841723
05022 Pathways of neurodegeneration - multiple diseases
138841723
09165 Substance dependence
05034 Alcoholism
138841723
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
138841723
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
138841723
04933 AGE-RAGE signaling pathway in diabetic complications
138841723
04934 Cushing syndrome
138841723
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
138841723
01524 Platinum drug resistance
138841723
01522 Endocrine resistance
138841723
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dmer01001
]
138841723
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
dmer03036
]
138841723
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
dmer04147
]
138841723
Enzymes [BR:
dmer01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
138841723
Protein kinases [BR:
dmer01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
138841723
Chromosome and associated proteins [BR:
dmer03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
138841723
Exosome [BR:
dmer04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
138841723
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
Kdo
FTA2
Motif
Other DBs
NCBI-GeneID:
138841723
NCBI-ProteinID:
XP_069898652
LinkDB
All DBs
Position
Unknown
AA seq
325 aa
AA seq
DB search
MVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEA
MRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI
NTNCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI
LAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAK
LFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLKQYYDPTDEPVAEEPFTFDMELDD
LPKERLKELIFQETARFQPGGPDAP
NT seq
978 nt
NT seq
+upstream
nt +downstream
nt
atggtcagctccgcttatgaccacgtgcgtaagactcgggtggccatcaagaagatcagc
ccctttgagcatcagacctactgccagcgcacactccgggagatccagatcctgctgcgc
ttccgccatgagaatgtcataggcatccgagacattcttcgggcacccacactggaagcc
atgagggatgtctacattgttcaggacctgatggagacagatctatacaaattgctcaaa
agccagcagctgagcaatgaccacatctgctacttcctctaccagatcctgcgtggcctc
aagtatatccactcggccaatgtgctccaccgggacctgaagccctccaacctgctcatc
aacaccaactgcgaccttaagatatgcgatttcggcctggcccgcattgcagatcctgaa
catgaccacacgggctttctgacggaatatgtggccacacgctggtaccgggcccccgag
atcatgcttaactccaagggctataccaagtccatcgacatctggtctgtgggctgcatt
ctggctgaaatgctctccaatcggcccatcttccctggcaagcactacctggaccagctc
aaccacattctgggtatcctgggctccccatcccaggaagacctgaactgtatcatcaac
atgaaggcccgaaactacctacagtctctgccatccaagaccaaggtggcttgggccaag
ctctttcccaagtcagactccaaagctcttgacctgctggaccggatgttaaccttcaat
cccaacaagcggatcaccgtggaggaagcccttgcccacccctacctgaagcagtactac
gatcccacggatgagccagtggctgaggagcccttcactttcgacatggagctggatgac
ctacccaaggagcggctgaaggagctcatcttccaggagacagcccgcttccagccaggg
ggcccagacgccccttaa
DBGET
integrated database retrieval system