Desulfoferula mesophila: FAK_33510
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Entry
FAK_33510 CDS
T09861
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
dmp
Desulfoferula mesophila
Pathway
dmp00790
Folate biosynthesis
dmp01100
Metabolic pathways
dmp01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
dmp00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
FAK_33510 (folC)
Enzymes [BR:
dmp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
FAK_33510 (folC)
6.3.2.17 tetrahydrofolate synthase
FAK_33510 (folC)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
BEQ16285
UniProt:
A0AAU9EXP2
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Position
3609507..3610817
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AA seq
436 aa
AA seq
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MSPRGQSAYEKAVSKLYELQKFGIKLGLSSTANLLEGLGNPHRGLACVHLAGTNGKGSVG
AMLEAALIQAGVKVGFYTSPHLERFTERFRVNGKEISQAGVVRLCQKVCKVVDLREPPTY
FEFVTAMAFEHFRDQGVELAIMETGLGGRLDATNICEPLVTVITNLSREHEDYLGKGLAN
IAFEKAGIIKPGVPLVHGVTQPKARKIVEDTAGAKGAPIYRRGRELTFRRAASGAFHLRG
RLWSLPHQTTNLVGRHQPVNACLALGAAEVLAEKGLPLGPEHLAAGMNQVHWPGRLEQWP
AEAGQPPLWLDGAHNPGAAYALLASLEDMRGGRKPLVMVVGVMADKEVGKLLSILLPAAD
RVVYSRPVYARAATPEALAAAAPLDAPPGEIEPNLERAMGRARELAGPQGVVLVTGSLFT
VGEARTILSGGISDLP
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgtcgccccgtggccagagcgcctatgaaaaggcggttagcaagctctacgagctgcaa
aagttcggcatcaagctggggctcagctccacggccaacctgctggaaggcctgggcaac
ccgcaccggggcctggcctgcgtccacctggcgggcaccaacggcaagggcagcgtgggg
gccatgctggaggcggccctgatccaggccggggtcaaggtggggttctacacctcccct
catctggagcgcttcaccgagcgcttccgggtgaacggcaaagagatcagccaggccggg
gtggtcaggctgtgccaaaaggtgtgcaaggtggtggaccttcgcgagccgcccacctac
ttcgagttcgtcaccgccatggcctttgagcacttccgcgaccagggggtggagctggcc
atcatggagaccggcctgggcggccgcctggacgccaccaacatctgtgagcccctggtc
acggtgatcaccaacctgagccgggagcacgaggactacctgggcaagggcctggccaac
atcgcctttgaaaaggcggggatcatcaagcccggcgtgcccctggtgcacggggtgacc
cagcccaaggcccgcaagatcgtggaggacaccgccggggccaagggggcgcccatctac
cgccggggccgggagctaaccttccgccgcgccgcgtcgggggccttccacctgcgcggg
cggctgtggtccctgccccatcagaccaccaacctggtgggccgccaccagccggtgaac
gcctgcctggccctgggcgcggccgaggtgttggccgaaaagggcctgcccctgggacca
gagcacctggccgcgggaatgaaccaggttcactggcccgggcggctggagcagtggccc
gccgaggcgggccagccgcccctgtggctggacggggcccacaaccccggcgcggcctac
gcgctcctggccagcctggaggacatgcgggggggccgcaagcccctggtgatggtggtg
ggggtgatggccgacaaggaggtgggcaagctgttgagcatcctgcttcctgccgccgac
cgggtcgtctattcccggccggtatacgcccgggccgccacgcccgaagcgctggccgcc
gccgccccgttggacgccccgccgggggagatagagccgaacctggaaagggccatgggt
agggcccgtgagctggccggcccccaaggggtggtactcgtcacgggcagcctgttcacc
gtgggcgaagcccgaaccatcctgagcggcggcattagcgacttgccttaa
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