Dromaius novaehollandiae (emu): 112984876
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Entry
112984876 CDS
T07572
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
dne
Dromaius novaehollandiae (emu)
Pathway
dne00270
Cysteine and methionine metabolism
dne00480
Glutathione metabolism
dne01100
Metabolic pathways
dne01240
Biosynthesis of cofactors
dne04216
Ferroptosis
Module
dne_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
dne00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
112984876 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
112984876 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
112984876 (GCLC)
Enzymes [BR:
dne01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
112984876 (GCLC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
112984876
NCBI-ProteinID:
XP_025958835
Ensembl:
ENSDNVG00000016695
LinkDB
All DBs
Position
Unknown
AA seq
636 aa
AA seq
DB search
MGLLSQGSPLSWEETRRHAEHVRKHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVXLVLCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPECEPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVVDGCGSAQNGTGTDTEEYALMSIDTIINGKEGFFPGLIPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEMNY
SLIWKCNQIAQGQAECPELLGVGFNKKPSGNKTDSL
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctgagctgggaggagacgcggcggcacgcggag
cacgtgcgcaagcacggcatcctccagttcctccacatctaccgcgccctgcgcgaccgc
cacaaggacgtgctcaagtggggcgacgaggtggaatatatgttagtaaaatttgaccat
gagaataagaaggtacrcttggtgctatgtggtgaagaagttcttcaaacactgcaagac
aagggggaaaaggtaaaccccaatcacccaacactgtggcgaccagagtatggaagctat
atgattgaagggacacctggacagccrtatgggggaacgatgtctgaatttaataccgta
caagacaacatgaggaaaagaaggcaagaggctgcttctgtgcttaaagaaaatgaggct
gtttgcactgtgacgtcatttccaaggttagggtgtcctggatttacactgccagaatgt
gagccaacaccagtagaaggaggagcatcaaaatccctgttttttccagatgaagccatc
aataaacatcctagattcagtacactgaccagaaatattcggcaccgaagaggagagaag
gtcgtgataaatgtaccaatatttaaagataagaacacgccatcaccatttatagaaaca
tttcctaatgatgatggagaagcagcaaaagcggctaaaccagactatatatatatggat
gctatgggttttggaatgggaaactgctgtcttcaggtaacattccaggcttgcagcatt
tctgaagcaagatacctctatgatcagctagccacaatctgtccaattgtgatggcgttg
agtgctgcatctccgttctacagaggctatgtgtctgatattgattgtcgctggggagta
atctctgcatctgtagatgatcgaacacgagaagagagggggctagagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcacctgata
aaggaaggtattgatcaccttttggcacagcatattgcacacttgttcattcgagaccca
ttgactttatttgaggagaaaatacacctagatgatgcgaatgaatctgaccattttgag
aatattcagtctacaaactggcaaacaatgagatttaaaccacctcctccaaattcggat
attggatggcgagtggaattcaggcctatggaggtccagttaacagactttgaaaactct
gcttatgttgtgtttgtggtattgcttaccagagtgattctgtcgtacaaactagatttc
ctcattcctttgtccaaggtggacgaaaacatgaaggtggcccagaaaagagatgctgtc
cgtcaggggatgttttacttcaggaaggatatttgtaaaggtggaaatgctgttgtggat
ggatgtggctctgcacagaatggcacaggcacagacacggaagagtacgccctaatgagc
attgatacaattatcaatgggaaggaaggattctttcctggtttgatcccaattttgaat
tcttatcttgaaaacatggaagtggatgtggacacaagatgcaccatcctaaactacctg
aagttaataaaaaagagagcatctggagagttaatgacagttgcccgatggatgagggaa
tttatcgcacagcatccagactacaagcaagacagcgtgataactgatgaaatgaattat
agccttatctggaaatgcaaccaaattgcacaaggccaggcagagtgtcctgaactgttg
ggagtaggatttaacaagaaaccaagtggaaacaaaactgactctttgtaa
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