KEGG   Dasypus novemcinctus (nine-banded armadillo): 101421932
Entry
101421932         CDS       T07872                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
dnm  Dasypus novemcinctus (nine-banded armadillo)
Pathway
dnm01522  Endocrine resistance
dnm04010  MAPK signaling pathway
dnm04012  ErbB signaling pathway
dnm04014  Ras signaling pathway
dnm04024  cAMP signaling pathway
dnm04068  FoxO signaling pathway
dnm04071  Sphingolipid signaling pathway
dnm04137  Mitophagy - animal
dnm04140  Autophagy - animal
dnm04141  Protein processing in endoplasmic reticulum
dnm04210  Apoptosis
dnm04215  Apoptosis - multiple species
dnm04217  Necroptosis
dnm04310  Wnt signaling pathway
dnm04380  Osteoclast differentiation
dnm04510  Focal adhesion
dnm04517  IgSF CAM signaling
dnm04530  Tight junction
dnm04620  Toll-like receptor signaling pathway
dnm04621  NOD-like receptor signaling pathway
dnm04622  RIG-I-like receptor signaling pathway
dnm04625  C-type lectin receptor signaling pathway
dnm04657  IL-17 signaling pathway
dnm04658  Th1 and Th2 cell differentiation
dnm04659  Th17 cell differentiation
dnm04660  T cell receptor signaling pathway
dnm04664  Fc epsilon RI signaling pathway
dnm04668  TNF signaling pathway
dnm04722  Neurotrophin signaling pathway
dnm04723  Retrograde endocannabinoid signaling
dnm04728  Dopaminergic synapse
dnm04750  Inflammatory mediator regulation of TRP channels
dnm04910  Insulin signaling pathway
dnm04912  GnRH signaling pathway
dnm04914  Progesterone-mediated oocyte maturation
dnm04917  Prolactin signaling pathway
dnm04920  Adipocytokine signaling pathway
dnm04926  Relaxin signaling pathway
dnm04930  Type II diabetes mellitus
dnm04931  Insulin resistance
dnm04932  Non-alcoholic fatty liver disease
dnm04933  AGE-RAGE signaling pathway in diabetic complications
dnm04935  Growth hormone synthesis, secretion and action
dnm04936  Alcoholic liver disease
dnm05010  Alzheimer disease
dnm05012  Parkinson disease
dnm05016  Huntington disease
dnm05017  Spinocerebellar ataxia
dnm05020  Prion disease
dnm05022  Pathways of neurodegeneration - multiple diseases
dnm05132  Salmonella infection
dnm05133  Pertussis
dnm05135  Yersinia infection
dnm05142  Chagas disease
dnm05145  Toxoplasmosis
dnm05152  Tuberculosis
dnm05161  Hepatitis B
dnm05162  Measles
dnm05166  Human T-cell leukemia virus 1 infection
dnm05167  Kaposi sarcoma-associated herpesvirus infection
dnm05169  Epstein-Barr virus infection
dnm05170  Human immunodeficiency virus 1 infection
dnm05171  Coronavirus disease - COVID-19
dnm05200  Pathways in cancer
dnm05208  Chemical carcinogenesis - reactive oxygen species
dnm05210  Colorectal cancer
dnm05212  Pancreatic cancer
dnm05231  Choline metabolism in cancer
dnm05415  Diabetic cardiomyopathy
dnm05417  Lipid and atherosclerosis
dnm05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dnm00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    101421932 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101421932 (MAPK8)
   04012 ErbB signaling pathway
    101421932 (MAPK8)
   04014 Ras signaling pathway
    101421932 (MAPK8)
   04310 Wnt signaling pathway
    101421932 (MAPK8)
   04668 TNF signaling pathway
    101421932 (MAPK8)
   04068 FoxO signaling pathway
    101421932 (MAPK8)
   04071 Sphingolipid signaling pathway
    101421932 (MAPK8)
   04024 cAMP signaling pathway
    101421932 (MAPK8)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    101421932 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101421932 (MAPK8)
   04137 Mitophagy - animal
    101421932 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    101421932 (MAPK8)
   04215 Apoptosis - multiple species
    101421932 (MAPK8)
   04217 Necroptosis
    101421932 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101421932 (MAPK8)
   04530 Tight junction
    101421932 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101421932 (MAPK8)
   04621 NOD-like receptor signaling pathway
    101421932 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    101421932 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    101421932 (MAPK8)
   04660 T cell receptor signaling pathway
    101421932 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    101421932 (MAPK8)
   04659 Th17 cell differentiation
    101421932 (MAPK8)
   04657 IL-17 signaling pathway
    101421932 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    101421932 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101421932 (MAPK8)
   04920 Adipocytokine signaling pathway
    101421932 (MAPK8)
   04912 GnRH signaling pathway
    101421932 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    101421932 (MAPK8)
   04917 Prolactin signaling pathway
    101421932 (MAPK8)
   04926 Relaxin signaling pathway
    101421932 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    101421932 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    101421932 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    101421932 (MAPK8)
   04722 Neurotrophin signaling pathway
    101421932 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101421932 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101421932 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101421932 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    101421932 (MAPK8)
   05231 Choline metabolism in cancer
    101421932 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101421932 (MAPK8)
   05212 Pancreatic cancer
    101421932 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101421932 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    101421932 (MAPK8)
   05161 Hepatitis B
    101421932 (MAPK8)
   05171 Coronavirus disease - COVID-19
    101421932 (MAPK8)
   05162 Measles
    101421932 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101421932 (MAPK8)
   05169 Epstein-Barr virus infection
    101421932 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101421932 (MAPK8)
   05135 Yersinia infection
    101421932 (MAPK8)
   05133 Pertussis
    101421932 (MAPK8)
   05152 Tuberculosis
    101421932 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101421932 (MAPK8)
   05142 Chagas disease
    101421932 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101421932 (MAPK8)
   05012 Parkinson disease
    101421932 (MAPK8)
   05016 Huntington disease
    101421932 (MAPK8)
   05017 Spinocerebellar ataxia
    101421932 (MAPK8)
   05020 Prion disease
    101421932 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    101421932 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101421932 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    101421932 (MAPK8)
   05415 Diabetic cardiomyopathy
    101421932 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101421932 (MAPK8)
   04936 Alcoholic liver disease
    101421932 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    101421932 (MAPK8)
   04931 Insulin resistance
    101421932 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101421932 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101421932 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dnm01001]
    101421932 (MAPK8)
Enzymes [BR:dnm01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101421932 (MAPK8)
Protein kinases [BR:dnm01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101421932 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH
Other DBs
NCBI-GeneID: 101421932
NCBI-ProteinID: XP_004454917
LinkDB
Position
Unknown
AA seq 372 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKGNVHQIH
GDQTEGPLGFSC
NT seq 1119 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattctacattc
acagtcttaaaacggtatcagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaacgttgcaatcaagaagctaagccgacca
tttcagaatcaaactcatgctaagcgggcttacagagaactagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccccagaaatccctagaagaa
tttcaggatgtttacattgtcatggagctcatggacgcaaatctctgccaagtgattcaa
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactagccagaactgcaggaaccagtttt
atgatgacaccgtatgtagtaactcgctactaccgagctccagaggtcatcctggggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactgcaaccaacagtaaggacttacgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccccgatgtacttttc
ccagctgattcggaacacaacaaacttaaagccagccaggcaagggatttgttgtccaaa
atgctagtaatagatgcatctaaaaggatctctgtggatgaagcactccagcacccatat
atcaacgtctggtatgatccttctgaagctgaagctccaccaccaaagatccctgacaag
cagttagatgaaagggaacatacaatagaagaatggaaaggtaacgttcatcagattcat
ggagatcaaactgagggaccattgggcttttcatgttga

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