| Entry |
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| Symbol |
SIRT1
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| Name |
(RefSeq) LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1
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| KO |
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| Organism |
dnm Dasypus novemcinctus (nine-banded armadillo)
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| Pathway |
| dnm00760 | Nicotinate and nicotinamide metabolism |
| dnm04213 | Longevity regulating pathway - multiple species |
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| Brite |
KEGG Orthology (KO) [BR:dnm00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
101424120 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
101424120 (SIRT1)
04068 FoxO signaling pathway
101424120 (SIRT1)
04152 AMPK signaling pathway
101424120 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101424120 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
101424120 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101424120 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
101424120 (SIRT1)
04213 Longevity regulating pathway - multiple species
101424120 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101424120 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
101424120 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101424120 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:dnm03036]
101424120 (SIRT1)
03029 Mitochondrial biogenesis [BR:dnm03029]
101424120 (SIRT1)
Enzymes [BR:dnm01000]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
101424120 (SIRT1)
Chromosome and associated proteins [BR:dnm03036]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
101424120 (SIRT1)
Mitochondrial biogenesis [BR:dnm03029]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
101424120 (SIRT1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
733 aa
MADEAALALQPGGSPSVAAAEREAGSPPVGEPLRKRLRRDGPGFGRTPGEPGGAAPEREM
PAVAALWREVPAAGGEREAQEAGATGGDNGPGLQALSRELPPVDDFYEDDDDEGEEEEEA
AAAAIGYRDNLLFGDEIITNGFHSCESDEDDRASHASSSDWTPRPRIGPYTFVQQHLMIG
TDPRTILKDLLPETIPPPDLDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKK
IIVLTGAGVSVSCGIPDFRSRDGIYARLAIDFSTFSDPQAMFDIEYFRKDLRLIFKFAKE
IYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICK
YKVDCEAVRGDIFDQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDL
LIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGG
EYAKLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLNISEDSSSPERTSPDSSVIVTLL
DQGTKNKVDDLDVLESKGCNEEKSQVIQTSTRNTENIPEQLESPDLKNVGSITGEKNERT
SVAETVRKCWPTRLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSN
SDSGTCHSPSLEEHMEDESEIEEFYNGLEDDADVPERGGVTGFGADGGDQEAVNEATSVK
QEAVDINYPSNKS |
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| NT seq |
2202 nt +upstreamnt +downstreamnt
atggcggacgaggcggcgctcgcccttcagcccggcgggtccccctctgtggcggcggcc
gagagggaggccgggtcgccgccagtaggggagccgctccggaagaggctgaggagagac
ggccctggcttcgggcggacaccgggcgagcccggaggggcggccccagagcgtgagatg
ccggcggtggcggcgctgtggcgggaggtgccggccgcgggcggggaacgggaggcccag
gaggccggggcaacaggaggagacaatgggccgggcctgcaggccctatcccgggagctg
ccgccggtcgacgacttctacgaagacgacgacgacgaaggcgaggaagaggaagaggcg
gcggcggcggcgattgggtaccgagataaccttctgttcggtgatgaaattatcaccaat
ggctttcattcctgtgaaagtgatgaggatgatagagcctcacatgcaagctctagtgac
tggactccaaggccacggataggtccatatacttttgttcagcaacatctcatgattggc
acagaccctcgaacaattcttaaagatttactaccagaaacaattcctccacctgacttg
gatgatatgacattgtggcagatcgttattaatatcctttcagaaccaccaaaaaggaaa
aaaagaaaagatattaatacaattgaagatgctgtgaaattactgcaagagtgcaaaaaa
ataattgttctaacaggagctggggtgtctgtttcctgtggaatacctgacttcaggtcg
agagatggtatttatgcacgccttgcaatagacttctctaccttctcagatcctcaagca
atgtttgatattgaatatttcagaaaggatctcagactcattttcaagtttgcaaaggaa
atatatcccggacagttccaaccatctctttgtcacaaattcatagccttgtcagataag
gaaggaaaactacttcgcaactatactcagaacatagatacactggaacaggttgcagga
atccaaaggataattcagtgtcacggttcttttgcaacagcatcttgcctgatttgtaaa
tataaagttgactgtgaagctgtacgaggagatatttttgatcaggtggttcctcgatgt
cctaggtgcccagctgatgaaccactggctattatgaaaccagaaattgtcttttttggt
gaaaatttaccagaacagtttcacagagccatgaagtatgacaaagatgaagtcgatctc
ctcattgttattgggtcttccctgaaagtacgaccagtagcactaattccaagttccata
ccccatgaagtgcctcagatattaattaatagggaacctttgcctcatctgcattttgat
gtggagcttcttggagactgtgatgtcataattaatgagttgtgtcataggttaggtggt
gaatacgccaaactttgctgcaaccctgtaaagctttcagaaattactgaaaaacctcca
cgaacacaaaaagagttggctcatttgtcagagttgccacccacacctcttaatatttca
gaagactcaagttcaccagaaagaacttcacctgattcttcagtgattgtcacactttta
gatcaaggtaccaagaataaagttgatgatttagatgtgttggaatcaaaaggttgtaat
gaagaaaaatcacaggtaatacagacttctactaggaacactgaaaatattcctgaacag
ttggagagtccggatttgaagaacgttggctccattactggggagaaaaatgaaagaact
tcagttgccgaaacagtgagaaaatgctggcctactagacttgcaaaggagcagatcagt
aagcggcttgatggtaatcagtatctgtttttaccaccgaatcgttacattttccatggc
gctgaggtatattcagactcagaagatgatgtcttatcctctagttcttgtggcagtaat
agtgatagtggaacttgccacagtccaagtttagaagaacacatggaggatgaaagtgag
attgaagaattctacaatgggttggaggatgatgctgatgttccagagcgaggtggagta
actggctttggggctgatggaggtgaccaagaggcagttaatgaagctacatctgtgaaa
caggaagcagtggacattaattatccatcaaacaaatcataa |
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