| Entry |
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|---|
| Name |
(RefSeq) E3 ubiquitin-protein ligase HERC2
|
|---|
| KO |
|
|---|
| Organism |
dnm Dasypus novemcinctus (nine-banded armadillo)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:dnm00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101425696
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:dnm04121]
101425696
03036 Chromosome and associated proteins [BR:dnm03036]
101425696
03400 DNA repair and recombination proteins [BR:dnm03400]
101425696
Enzymes [BR:dnm01000]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
101425696
Ubiquitin system [BR:dnm04121]
Ubiquitin ligases (E3)
HECT type E3
101425696
Chromosome and associated proteins [BR:dnm03036]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
101425696
DNA repair and recombination proteins [BR:dnm03400]
Eukaryotic type
DSBR (double strand breaks repair)
Other DSBR factors
Ubiquitin ligases
101425696
|
|---|
| SSDB |
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|---|
| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
|
|---|
| AA seq |
4828 aa
MGSTFTYWQEELAFTRDGLCGLWNEMVKDGEIIYTGTELTQNGELPPRKDDGVDSHSGTK
KEDLNDKEKKDEEETPVPTYRAKSILESWVWGRQPDVNELKECLSVLVKEQQALAIQSAT
STLSAMRLKQRLVILERYFIALNRTVFQENVKVKWKSSSISLPPVDKKSSRPTGKGVEGL
ARVGSRAALSFAFAFLRRAWRSGEDADLCSELLQESLDALRALPEASLFDESTVSSVWLE
VVERATRFLRSVVTGDVHGAPGTKGPGSIPLQDQHLALAILLELAVQRGTLSQMLSAIML
LLQLWDSGTRETDNERSAQGTSAPLLPLLQRFQSIVCCKDTPHSDGDTHLLSGPLSPNES
FLRYLTLPQDNELAIDLRQTAVVVMAHLDRLAAPCMPPLCSSPTSHKGSLQEVIGWGLIG
WKYYANVIGPIQCEGLANLGVTQIACAEKRFLILSRNGRVYTQAYNSDTLAPQLVQGLAS
RNIIKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKH
VVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGS
GDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIAL
TKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHS
WGSNDQCQHFDTLRVTKPEPAALPGLDTKHIVGIACGPAQSFAWSSCSEWSIGLRVPFVV
DICSMTFEQLDLLLRQVSEGMDGTADWPPPQEKECMAVATLNLLRLQLHAAISHQVDPEF
LGLGLGSVLLNSLKQTVVTLASSVGVLSTVQSAAQAVLQSGWSVLLPTAEERARALSALL
PCAVSGNEVNISPGRRFMIDLLVGSLMADGGLESALNAAITAEIQDIEAKKEAQKEKEID
EQEANASTFHRSRTPLDKDLINTGIYESSGKQCLPLVQLIQQLLRNIASQTVARLKDVAR
RISLCLDFEQHSHERSASLDLLLRFQRLLISKLYPGESIGQTSDISSPELMGVGSLLKKY
TALLCTHIGDILPVAASIASTSWRHFAEVACIVEGDFTGVLLPELVVSTVLLLSKNAGLM
QEAGAIPLLGGLLEHLDRFNHIAPGKERDDHEDLAWPGIMESFFTGQNCRNNEEVTLIRK
ADLENHNKDGGFWTVIDGKVYDIKDFQTQSLTGNSILAQFAGEDPVVALEAALQFEDTRE
SMHAFCVGQYLEPDQEVVTIPDLGSLSSPLIDTERNLGLLLGLHASYLAMSTPLSPVEVE
CAKWLQSSIFSGGLQTSQIHYSYNEEKDEDHCSSPGGTPASKSRLCSHRRALGDHSQAFL
QAIADSNIQDHSVKDFLCQIERYCKQCHLTTPITFPPEHPVEEVGRLLLCCLLKHEDLGH
VALSLVHAGTLGFEQVKHRTLPKSVVDVCRVVYQAKCSLIKTHQEQGRSYKEVCAPVIER
LRFLFNELRPAVCNDLSIMSKFKLLSSLPRWRRIVQKIIRERRKKRVPKKPESTDDEEKI
GNEESDLEEACILPHSPINMDKRPITIKSPKDKWQPLLSTVTGVHKYKWLKQNVQGLYPQ
SALLSTIAEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDTILKLATKNFLLPSVQYAM
FCGWQRLIPEGIDIGEPLTDCLKDVDLIPPFNRMLLEVTFGKLYAWAVQNIRHVLMDANA
KFKELGIQPVPLQTITNENPSGPSLGTIPQARFLLVMLSMLTLRHGAHNLDLLLNSGTLA
LTQTALRLIGPSSDNAEEDMNASARGASATVLEETRKETTHVQLPVSGPELAAMMKIGTR
VMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQWDTGSTNSYRMGKEGKYDLKLAELP
PSTQPSAEDSDTEDDSEAEQFERNIHPTSMMLTSTINLLQTLCLSAGVHAEVMQSEATKT
LCGLLRVLVESGTTDKALLPNKVVFKEQHRSWCTLGFVRSIALTPQMCGALSSPQWIALL
MRIVEGHAPFTAASLQRQILAVHLLQAVLPSWDKAERSRDMKCLVEKLFGFLGSLLTTCS
SDIPLLRESTLRRRRARPQASLTATHSSTLAEEVVALLRTLHSLSQWNGLINKYINSQLH
SVTPSFAGKQSEGAQLEDYFPDSENPEVGGLMAVLAVIGGIDSRLRLGGQVTHEEFGEGT
VTRITPKGRITVQFSDMRVCRVCPLNQLKPVPAVAFSVTNLPFTEPMLSVWAQLVNLAGS
KLEKHKIKKSPKQAFRRSVHAQVDLDLLRCQQLKLYILKAGRALLSHQDKLRQILSQPAI
QETGTVHTDDGAVASPDLGDMSPEGPQPPMILLQQLLASATQPSPVKAMFDKQELEAAAL
AVCQCLAVESTHPSSPVFEDCSSSEATTPVPVQHLRSVRVKKHKPSPVPALPIVVQLMEM
GFPRRNIEFALKSLTGASGNASGMPGIEALVGWLLDHSDVQITDLSDADTVSDEYSDEEL
VEDTDEASYPVSTGAVVTESQTYKKRADFLSNDDYAVYVRENIQVGMMVRCCRTYEEVCE
GDVGKVIKLDRDGLHDLNVQCDWQQKGGTYWVRYIHVELIGYPPPSSPSHIKIGDKVRVK
TSVTTPKYKWGSVTHQSVGVVKAFSANGKDVIVDFPQQSHWTGLLSEMELVPSIHPGVTC
DGCQMFPINGSRFKCRNCDDFDFCETCFKTRKHNTRHTFGRINEPGQSAVFCGRSGKQLK
RCHSSQPGTLLDSWSRMVKSLNVSSSVNQAARLIDGSEPCWQSSGSQGKHWIRLEIFPDV
LVHRLKMIVDPADSSYMPSLVVVSGGNSLNNLIELKTININPTDTTVPLLSDCTEYHRYI
EIAIKQCRSSGIDCKIHGLIILGRIRAEEEDLAAVPFLASDNEEEDDDKGNSGSLIRKKS
SGLESAATIRTKVFVWGLNDKDQLGGLKGSKIKIPSFSETLSALNVVQVAGGSKSLFAVT
VEGKVYACGEATNGRLGLGISNGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKV
FSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEY
GRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRG
GSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKP
QVVEGLRGKRIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEG
QRITRVACGSSHSVAWTTVDVATPSVHEPVLFQTARDPLGASYLGVPSDADSSAASNKIS
GANISKPNRPSLAKILLSLDGNLAKQQALSHVLTALQIMYARDVVVGALMPAGMIAPVEC
PSLSSPVPPADMPAMVSPMNGEECVLAFDLEDRLSPNPWQEKRGEMISSEDAVTPSAVTP
SASSASSRPFIPVTDDPGAASIIAETMTKTKEDVENQNKASGPEPEYLDEFTSLLIADDT
RVVVDLLKLSVCSRAGDKGKDVLSAVLSGMGTAYPQVADMLLELCVTELEDVATDSQSGR
LSSQPVVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVMDGVNRIVS
VRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDLLSDRCILS
CPSMDLVTCLLDFRLNLASNRSIVPRLAASLAACAQLSALAASHRMWALQRLRKLLTTEF
GQSININRLLGDNDGETRALSFTGSALAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPF
FKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRLFLDEVAKKIR
ELMADGENMDVLHESHDVFKREQDEQLVQWMNRRPDDWTLSAGGSGTIYGWGHNHRGQLG
GIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVS
TPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIE
SLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVV
DIACGSGDAQTLCLTDGDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGS
QFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTE
DGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSKPASAGK
LPAQVPMEYNHLQEIPIIALRNRLLLLHHISELFCPCIPMFDLEGYLDETGLGPAVGFDT
LRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKGGLAGPDGTKSVFGQ
MCAKMSSFSADSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLTVTPN
GRDESGANRDCYLFNPAARAPVHTNMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMS
LTIADLSEVDKDFIPGLMYIRDNEAAAEEFEAMGLPFTVPSAGGQDVQLSAKHTHITLDN
RAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLK
SVATYKGIEPSAPLMQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVVQVL
DKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALTGEPA
ADDSSDDSDNEDADSFASDSTQDYLTGH |
|---|
| NT seq |
14487 nt +upstreamnt +downstreamnt
atggggtcaacattcacctactggcaagaagagcttgcattcaccagagatggactctgt
ggtctgtggaatgaaatggttaaagatggagaaattatatatactggaacagaattaaca
cagaatggagagctccctcctagaaaagatgatggtgttgatagtcacagtggaacaaag
aaagaagatctgaatgacaaagagaaaaaggatgaagaagaaactcctgtgcctacctac
agggccaaatcaatcttggagagttgggtatggggcaggcaaccagatgtgaatgaactg
aaggaatgtctttctgtgttggttaaagagcagcaagctctggccatccagtcagccaca
agcaccctttcagccatgagactcaagcaaaggctggttattttggaaagatacttcatt
gccttgaatagaactgtttttcaggagaatgtcaaggttaagtggaaaagcagcagtatt
tctctacctcctgtggacaaaaaaagttcccgacctacaggcaaaggggttgaaggactt
gcaagagttggatcccgagcagctctttcttttgcctttgcattcttacgcagggcctgg
cgttcaggtgaggacgcagacctctgcagtgagctgttgcaggagtccctggatgccctc
cgagctcttcctgaggcttctctctttgatgagagcacagtgtcctctgtgtggctggag
gtggtggaaagagcaaccagattcctcaggtctgtcgtgacgggagatgttcacggagca
cctggcaccaaaggaccgggaagcatccccttgcaggaccagcacttagccctggccatc
ttgttagagctggctgtgcagaggggcacactgagccaaatgctatctgccatcatgttg
ttgctgcaactgtgggacagtgggacacgggagacggacaacgagcgctcagcacaggga
accagtgcccccctccttccactgctgcagaggtttcagagcatcgtctgctgtaaagac
acgcctcattcagatggtgacacacatctcttatctggccctctgagccccaatgagagt
ttcctgaggtaccttactctaccacaagacaatgagctagccatcgatttacgacagact
gcggttgttgtcatggcccatttagatcgcctggccgctccctgcatgcctcctttgtgt
agctctccaacgtctcataagggatcgttgcaagaagtcataggttggggtttaatagga
tggaaatactacgccaatgtaattggtccaattcaatgtgaaggccttgccaacctgggg
gtcacacagattgcctgcgcagagaagcgcttcctgatcttatcgcggaatggtcgcgtg
tacacacaggcctacaacagtgacacgctggccccgcagctggtccagggtcttgcctct
agaaacattataaagatagctgcacattctgatggtcaccattacctggccttggcagcc
actggagaggtttactcctggggctgtggggacggtggaagactgggccatggagacacc
gtgccgctggaggagcctaaggtgatttctgctttctctgggaagcaggcaggcaagcat
gttgtgcacatcgcgtgtgggagcacgtacagtgcagccatcactgctgagggcgagttg
tacacctggggccggggcaactacggcagactgggccatggttccagtgaagatgaggcc
attccgatgcttgtagctgggcttaaaggactgaaggtcatcgatgtggcgtgtgggagt
ggggatgctcaaactctggctgtgactgagaatggtcaagtgtggtcttggggagatggt
gactatgggaaattgggccgaggtggtagtgatggctgcaaaacgccaaagctgattgaa
aaacttcaagacttggatgttgtcaaagtacgctgtggaagtcaattttctattgctcta
actaaagatggccaagtttattcatggggaaaaggtgacaatcagagacttgggcatgga
acagaggaacatgttcgttatccgaaactattggaaggcttgcaagggaaaaaagtaatt
gatgtggcagcgggctccacccattgccttgcattgacggaagatagtgaggtccacagc
tggggcagcaatgatcagtgccagcactttgacaccttgcgggtgaccaaaccagaacct
gctgcactgccgggactggatacaaagcacatagttggaattgcctgtgggcccgcacag
agttttgcttggtcgtcttgttccgaatggtctattggcctccgtgtcccttttgtggtg
gacatctgctccatgacttttgagcagctggatctcctactacggcaagtgagtgaaggg
atggatggcaccgctgactggcccccaccccaggagaaagagtgtatggctgtggcaaca
cttaatcttctacggcttcagttgcatgctgctattagccaccaggttgacccagaattc
cttggtttaggtctgggcagtgttctcctgaacagtttgaagcagaccgtggtgacgctg
gccagcagtgtgggcgtcctgagcaccgtacagtcagctgcacaggcagtgcttcaaagc
gggtggtcagtgctgctgcccactgctgaggaaagggcacgggcgctctctgcactcttg
ccctgtgcagtttcaggcaatgaagtgaacataagtccgggtcgtcgattcatgattgat
cttctagtgggcagcttgatggctgatggagggttagagtcagccttgaatgcagccatt
actgcagaaattcaggacattgaagccaaaaaggaagcacagaaggaaaaagaaattgat
gaacaggaagcaaatgcctccacttttcatagaagtaggactccattggataaagacctc
attaatacagggatctatgaatcttctggaaaacagtgtttgcctctagttcagttaata
caacagcttctaagaaacattgcttctcagactgtggccagactgaaagatgttgctcgt
cggatttcattgtgcctggactttgagcagcacagccatgaaagatctgcttccctggat
ttgttactgcgttttcagcgtttgcttatcagtaaactttatccaggagaaagtattggt
cagacctcagatatttctagtcctgagctaatgggtgttggttccttgctgaaaaagtac
acagcccttttgtgcacacacattggagatatattgcctgtggctgctagcattgcttct
accagctggaggcactttgcagaggtggcctgcattgtagaaggagacttcactggtgtt
ctccttccagaactagtagtttctactgtgcttttgctcagtaaaaatgctggccttatg
caagaggctggagctattcccctgttgggtggcctattggaacatctagatcggttcaac
cacattgctccaggaaaagaaagggatgatcatgaagatttagcctggcctggcataatg
gagtcattttttacaggtcagaactgtagaaataatgaggaagtgacacttatacgcaaa
gctgatttggagaaccacaataaagatggaggcttctggacagtgattgatgggaaagtg
tatgatataaaggactttcagacgcagtctttaacagggaatagcattcttgctcagttt
gcaggagaagatcctgtcgttgctttggaagcagctttgcagtttgaagacacccgggag
tcgatgcatgcgttttgtgttggccagtatttggagcctgatcaagaagtcgttaccata
ccagacctgggaagtctctcttcacctcttatagacacagagagaaatctgggccttctc
ctcggattacatgcctcctacttggcaatgagtacaccgttgtctcctgttgaggttgaa
tgtgccaagtggcttcagtcatctatcttctctgggggcctgcagaccagccagatccac
tatagctacaacgaggagaaagatgaggaccactgtagctcccccggtggcactcctgcc
agcaaatcccggctatgctcccacagacgggccctgggtgaccattctcaggcattcctg
caagccatcgccgacagtaacattcaggaccacagcgtgaaggactttctgtgtcaaata
gaaaggtactgcaagcagtgccacttaaccacaccaatcacatttcctcctgagcatcct
gtggaagaggttggccgcttgctgttatgttgtctcttaaagcatgaagatttaggtcat
gtggcattatctttagttcatgcaggtactcttggttttgagcaagtcaaacacagaaca
ttgcctaaatcagtggtggatgtttgtagagttgtctaccaagcaaaatgctcactaatt
aagacacatcaagaacagggccgttcttataaggaggtctgcgcacctgtcatcgaacgt
ttgagattcctctttaatgaattgagacctgcagtgtgtaatgatctctcaataatgtct
aaatttaagctgttaagttctttgccccgttggaggaggatagtgcagaagataattcga
gaacgaaggaaaaagagagttcctaaaaagccagaatctactgatgatgaagaaaaaatt
ggaaatgaagagagtgatttagaagaagcttgcattttgcctcacagtcctataaatatg
gataaaagacccattacaatcaaatcacccaaggataaatggcagccattgttgagtaca
gtgacaggtgttcacaaatacaaatggctgaagcagaatgttcagggcctttatccacag
tctgctctcctcagtacaattgctgaatttgctcttaaagaagagccggtggatgtggaa
aaaatgagaaaatgcttattaaaacagttggagagagcagaggttcgcctggaaggaata
gatacaattttaaaactggcaaccaaaaatttcttacttccatctgtacagtatgctatg
ttttgtggatggcaaagacttattcctgaagggattgatataggggagccccttacagat
tgtttaaaggatgttgatctgatcccaccttttaaccggatgctgctggaagtaaccttt
ggcaagctgtatgcttgggctgttcagaatattcgacatgttttgatggatgcaaatgcc
aaatttaaagagcttggcatccagcctgttcccctgcaaacaattaccaatgagaacccg
tcgggccccagcctcgggaccatcccacaagctcgcttcctcctggtgatgctcagcatg
ctcacgctgcggcacggtgcccacaacctggacctcctgctcaactcgggcacgctggcc
ctcacgcagacggctttgcggctcatcggcccaagttctgacaatgctgaagaagacatg
aatgcttctgcccgcggcgcttcagctacggttttggaagaaacaagaaaggagacaact
cacgtgcagctgcctgtctcgggcccagagctggcagccatgatgaaaatcgggacccgg
gtcatgaggggcgtggactggaagtggggtgatcaggatggacctcctcctggtctaggt
cgtgtgataggtgaattgggagaggatggatggatcagggtccagtgggacacgggcagc
acgaactcgtacagaatgggaaaagaagggaagtatgacctcaagctggctgagctgcca
ccatccacgcagccttctgctgaggactcggacacagaagatgactccgaagctgaacag
tttgaaaggaacatccaccccacttcaatgatgctcacaagtactattaatttactacaa
actctctgtctctccgctggagtacatgctgaagtcatgcagagcgaagccaccaagact
ctgtgtggactgctgcgagtgttagtggagagcggaaccacagacaaagccttattacca
aacaaagtggtgtttaaagagcaacaccgaagctggtgcacactggggtttgtgcggagc
atcgctcttacgccgcagatgtgcggtgccctcagctccccgcagtggatcgccctcctg
atgaggattgtggagggccatgcgcccttcaccgcagcgtcgctgcagaggcagatctta
gctgtacatttactgcaagcagtgcttccttcctgggacaaggctgagcggtcaagggac
atgaaatgccttgtggagaaactgtttggcttcttgggcagcttgcttactacttgttct
tcggatatccctctgctcagagagtccactctgaggaggaggagggcccggccccaggcc
tcgctgactgccacacacagcagcacactagcagaggaggtggtggccctgctcaggacg
ctgcactcactgagccagtggaacggactcataaacaagtacatcaactctcagctccac
tccgtcacccccagctttgcaggaaagcagtctgaaggggcccagctggaggactatttc
cctgactcggagaacccagaagtggggggcctcatggcagtcctggctgtgattggtggg
attgacagccgcctgcgactgggaggtcaagtcacacatgaggagtttggagaaggcacc
gtgactcgcatcaccccgaagggcaggatcactgtgcagttttctgacatgcgggtgtgt
cgtgtgtgtcctttgaaccagctgaagccggtncctgctgtggcattcagtgtgaccaac
ctgcctttcacagagcccatgctgtctgtctgggctcagttggtaaaccttgctggaagc
aaattagaaaagcacaaaataaagaaatcacccaaacaggcctttcgcaggtcagtacat
gcacaagtagacctggatctgctgagatgtcaacaattaaaattgtacatattgaaagca
ggccgagcattgctttcccaccaagataaattacggcaaatcttgtctcaaccagctatt
caggagactggaactgttcatacagacgatggtgctgtcgcatcccctgaccttggagat
atgtctcctgaagggcctcagcccccaatgatcctcctgcagcagctgctcgcctcagcc
acccagccatcaccagtaaaggccatgtttgataaacaagaacttgaggctgctgctttg
gctgtgtgtcagtgcttggccgtggagtccacccacccatcgagccctgtgtttgaggac
tgcagctccagtgaggccaccacgccagtcccagtgcagcaccttcgctctgtcagggtg
aagaagcacaagccgtcgcctgtgcctgccctgcccattgtggttcagctcatggaaatg
ggatttcccaggaggaacatagagtttgcactgaagtcgctcactggagcttctgggaac
gcatctgggatgcctggtatcgaggctctggttgggtggcttctggaccactctgacgtc
cagatcacggacctctcggatgcagacactgtgtctgatgagtattcggatgaggagctg
gtggaggatacggatgaggcttcttaccctgtgtctactggtgctgttgtaacagagagc
cagacttataaaaaacgagctgatttcttaagtaatgatgattatgctgtctatgtgaga
gaaaatattcaggtgggaatgatggttagatgctgtcgaacatatgaagaagtgtgtgaa
ggagatgtgggcaaagttattaaactggacagagatggattacatgatctcaatgttcaa
tgtgattggcagcagaaaggaggtacctactgggttaggtatattcacgttgaacttata
ggttatccaccaccaagttctccttctcacatcaagattggtgataaagtacgagtcaaa
acctcagtaaccacaccaaaatacaaatggggatctgttactcatcaaagtgtgggggtt
gtgaaagcttttagtgccaatggaaaggatgtcattgtcgactttcctcagcagtctcac
tggactgggttgttatcagaaatggagttggtgcctagtattcatcctggagttacgtgt
gatggctgtcaaatgtttcccatcaatggatccagattcaaatgcagaaactgtgatgac
tttgatttttgtgaaacctgcttcaagaccagaaaacataacaccaggcatacatttggc
agaataaatgaaccagggcagtctgcagtgttttgtggccgttctggaaagcaactgaag
cgttgtcacagcagtcagccaggaacgctgcttgacagctggtcgcgcatggtaaagagc
ctgaatgtatcgtcctcggtgaaccaggctgcgcgcctgattgatggcagcgagccctgc
tggcagtcttctgggtcacagggaaagcattggattcgtttggagattttcccagatgtc
cttgttcatagattgaaaatgatagtagatcctgctgacagtagctacatgccttctctg
gttgtagtgtcaggtggaaattccctaaacaacctcatcgaactaaagacaatcaatatt
aaccccactgacaccacagtgccccttctgagtgactgcacagagtatcacagatatatt
gaaattgcgataaagcagtgcaggagctcgggaattgattgtaaaattcatggtctcatc
atactgggacggattcgtgcagaggaagaagatttggcagccgtccctttcttagcttca
gataatgaggaggaagatgatgataaaggcaacagtggaagtcttattagaaagaagtct
tcagggttggaatcagcagctacaataagaaccaaagtgtttgtatggggactgaatgac
aaggaccagctgggtggactgaaaggctctaagataaagattccttcattctctgagacc
ttatctgctttgaacgtagtacaggtggctggtggttctaaaagtttgtttgcagtgact
gtggaagggaaagtgtatgcatgtggagaagccaccaatggacggttggggctgggcatc
tccaatgggacagtgcccattcctcgacagattacggccctcagcaactacgtggtcaaa
aaggtggctgttcattcaggtggccggcatgctacagctctgactgtcgatggaaaagtg
ttttcatggggtgaaggagatgatggaaagctcggacacttcagcaggatgaactgtgac
aagccaaggctgatagaggctctgaaaaccaagcggatacgggacattgcctgtgggagc
tctcacagtgctgctatcacttccagtggggaactgtacacctggggccttggagagtat
ggccggttgggacatggggataacacaacacagctgaagcccaaaatggtgaaagtcctt
ctgggtcacagagtaatccaggttgcatgtggaagtagagatgcacagactctggctctg
accgatgaaggtttggtattttcctggggtgatggtgactttggaaaactgggccgggga
ggaagtgaaggctgtaacattccccagaacattgaaagactaaatggacagggggtttgc
cagattgagtgtggtgctcagttttccttggctcttacgaagtcaggagtagtgtggaca
tggggcaagggggattacttcagacttggccatggttcggatgtacatgtgcggaagccg
caggtggtagaaggactgcgggggaagaggattgtgcatgtggctgtgggggccctgcat
tgcctggcggtcactgacgcggggcaggtatatgcttggggtgacaatgaccacggacaa
cagggcaatggcacgaccacagttaacagaaagcccacacttgtccaaggcttagagggc
cagagaatcacacgagtggcttgtgggtcatctcacagtgtggcgtggacaaccgtagat
gtagcaactccctccgtccatgagcccgttctctttcaaactgcaagagaccctttaggt
gcttcctatttaggtgtgccttcagatgcagattcttctgctgccagtaataaaatcagt
ggtgcaaacatatctaagccaaatcgcccttctcttgccaagattctcttgtcattggat
ggaaatctggccaaacagcaggccttatctcatgtactaacagcgttgcaaatcatgtat
gccagagatgtggtggtgggagccttgatgccggctggcatgatcgcacctgttgagtgc
ccctcgctctcctccccggttcctcctgccgacatgccggccatggtcagtcccatgaat
ggagaagagtgtgtgctggcttttgatctcgaggacagactgagtccaaatccgtggcaa
gaaaagagaggagagatgatctcttctgaagatgctgtgactccctctgcagtgacccct
tctgcttcttcagcttcttctcggccatttatcccggtgacagatgaccctggagctgcc
agcatcattgcagaaaccatgaccaaaaccaaagaagatgttgaaaaccaaaataaagca
tccggcccagaacctgaatatttggatgaattcaccagtctgttaatcgcagacgacact
cgtgttgtggtggacctgctcaagctgtctgtctgcagccgtgctggggacaaaggcaag
gatgtcctctctgccgtgctgtctggaatgggcactgcctacccacaggtggcagatatg
ctgttggagctctgtgtcactgagttggaagatgtggcaacagactcgcagagtggccgt
ctctcctctcagccggtggtggtggagagcagccacccctatactgatgacacttccacc
agtggcacggtgaaaatcccaggcgcggaaggactcagggtggaattcgatcgacagtgc
tccaccgagcggcgccatgacccccttacagtcatggatggggtcaacaggatcgtctca
gtgcgatcaggccgtgaatggtccgactggtccagtgagctgcgcatcccaggggatgag
ctcaagtggaagttcatcagtgatgggtctgtgaatgggtggggctggcgcttcactgtc
taccccatcatgccagccgcaggccctaaagacctcctttctgaccgctgcatcctctcc
tgcccgtccatggacttggtgacatgtctgttagatttccggctcaaccttgcctctaat
aggagcatcgtcccccgcctggcggcctctcttgcagcatgtgcacagctgagtgcctta
gctgccagtcacagaatgtgggcccttcaaagactgaggaagctgcttacgactgaattt
gggcaatcaattaacataaataggctacttggagataatgatggagaaacaagagcattg
agctttacaggcagtgctcttgcagctttggtgaaaggccttccagaagctttgcaaagg
cagtttgaatatgaagatcctattgtgagaggtggtaaacagctactccacagcccattc
tttaaggtactagtagctcttgcttgtgacctagaactcgatactctcccttgctgtgct
gagacacacaagtgggcttggttcagaagatactgtatggcctcccgagttgctgtagcc
ttggacaaaagaacaccactgccccgtctgtttcttgatgaggtggctaagaaaattcgt
gaattaatggcagacggcgaaaacatggatgttctccatgagagccatgacgtttttaaa
agagagcaagatgaacaacttgtgcagtggatgaacaggcgaccagatgactggactctt
tctgctggtggcagtggaacaatttatggatggggacataatcataggggacagcttggg
ggcattgaaggtgcaaaagttaaagttccgactccgtgtgaagcccttgcaactcttaga
ccagtccagttaattgggggtgagcagactctctttgctgtgacagctgatgggaagcta
tatgccactgggtatggtgcagggggaagactaggaattggaggaacagaatctgtatct
accccaacgttacttgaatccattcaacatgtgtttattaagaaagtagctgtgaactca
ggaggaaaacactgtcttgccctctcttcagaaggagaagtttactcctggggtgaggca
gaagatggaaagttgggacatggcaacagaagtccctgtgaccgccctcgtgtgatcgag
tccctgaggggcatcgaagtggtggatgttgccgctggtggagcccacagtgcatgtgtc
acggctgccggggacctctacacgtggggcaaaggccggtatggccgcctggggcacagc
gacagcgaggaccagctaaagccaaagctggtggaggccctgcagggccaccgcgtggtg
gacattgcctgtggcagcggcgatgcgcagaccctctgcctcaccgatggtgacactgtc
tggtcctggggggacggggactacggcaagcttggcagaggaggcagtgacggctgcaag
gtgccaatgaagattgactcccttacaggcctcggagtggtgaaagtggaatgtggatcc
cagttttctgttgcactgaccaaatctggagctgtttatacttggggcaaaggtgattat
cacaggctgggccatggatccgatgaccatgtcagacgaccgcggcaagtccaagggctt
cagggaaagaaagtcattgcgattgccactggctccttacactgtgtgtgctgcacagag
gacggtgaagtttacacatggggtgacaatgatgagggacagcttggagatggaacaaca
aatgccatccagaggcctcgtctcgtcgctgctcttcagggtaaaaaggtcaatcgtgtg
gcctgtggctctgcacacacccttgcctggtcgaccagcaagcctgccagtgctgggaag
ctgcctgctcaggtccctatggagtataatcatttgcaggagattccaataattgcactg
cggaaccgactgctgctactgcatcatatctcagagctcttctgcccctgtatccccatg
tttgacctggagggctatctggatgaaacaggacttgggcctgcagtggggtttgacaca
ctacgaggaatccttatatcccagggcaaggaggcggctttccgaaaagtagtgcaagcg
actatggtgcgagatcgccagcatggtcctgtcgtagagctgaaccggatccaggtaaaa
cgttcaaggagtaaaggcgggctcgctggccctgatggcacaaaatctgtctttgggcag
atgtgtgctaaaatgagctcattcagtgcagacagcctcctcctcccacatcgcgtctgg
aaagtcaagtttgtgggtgaatctgtcgacgactgtggtggtggctacagcgagtctata
gccgagatctgtgaggagcttcagaatggactcactcctcttttgactgtgacgcccaat
gggagggatgagtcgggggccaaccgggactgctacctgttcaacccggctgccagggct
cccgtgcacaccaacatgttccgtttcctgggtgtgctactgggcattgccatccgaacg
gggagtccactgagcctcaaccttgccgagcctgtgtggaagcagctggctgggatgagc
ctcaccatcgccgacctcagcgaggtcgataaggatttcatccctgggctcatgtacatc
cgtgacaatgaggccgctgcggaggagtttgaggccatgggtctgcccttcacggtgcca
agcgcgggtggccaggatgtccagctgagcgccaagcacacccacatcacgctggacaac
cgggcggagtatgtgcgcctggcaatcaactatagactccatgaatttgatgagcaggtg
gctgcagttcgagaaggaatggcccgagtcgtgcctgtcccccttctttccctgtttact
ggatatgagttggaaaccatggtgtgtggaagcccggatatccctctgcacctcttgaaa
tcggtggcaacctataaagggattgagccctcagcgcccctgatgcagtggttctgggaa
gtgatggagtccttctccaacacggagcgctccctcttccttcgcttcgtgtggggccgg
accaggctcccgaggaccatcgccgacttccggggcagagactttgtggtccaggttctg
gataaatacaatccacctgatcacttccttcctgaatcatacacatgtttctttttgctg
aagttgcccaggtattcctgtaaacaggtgttggaggaaaaactgaaatatgccatccac
ttttgtaaatcaatagacacagatgattatgctcgcatagccctcacaggagagcccgca
gccgatgacagcagcgacgactctgacaatgaggatgcagactcctttgcttcagattct
acacaagactacttaacaggacactga |
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