Entry |
|
Symbol |
SRC
|
Name |
(RefSeq) proto-oncogene tyrosine-protein kinase Src
|
KO |
|
Organism |
dnm Dasypus novemcinctus (nine-banded armadillo)
|
Pathway |
dnm01521 | EGFR tyrosine kinase inhibitor resistance |
dnm04613 | Neutrophil extracellular trap formation |
dnm04625 | C-type lectin receptor signaling pathway |
dnm04750 | Inflammatory mediator regulation of TRP channels |
dnm04810 | Regulation of actin cytoskeleton |
dnm04919 | Thyroid hormone signaling pathway |
dnm05100 | Bacterial invasion of epithelial cells |
dnm05163 | Human cytomegalovirus infection |
dnm05167 | Kaposi sarcoma-associated herpesvirus infection |
dnm05168 | Herpes simplex virus 1 infection |
dnm05207 | Chemical carcinogenesis - receptor activation |
dnm05208 | Chemical carcinogenesis - reactive oxygen species |
dnm05418 | Fluid shear stress and atherosclerosis |
|
Brite |
KEGG Orthology (KO) [BR:dnm00001]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101426457 (SRC)
04015 Rap1 signaling pathway
101426457 (SRC)
04370 VEGF signaling pathway
101426457 (SRC)
09133 Signaling molecules and interaction
04081 Hormone signaling
101426457 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101426457 (SRC)
04137 Mitophagy - animal
101426457 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101426457 (SRC)
04520 Adherens junction
101426457 (SRC)
04530 Tight junction
101426457 (SRC)
04540 Gap junction
101426457 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101426457 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101426457 (SRC)
04613 Neutrophil extracellular trap formation
101426457 (SRC)
04625 C-type lectin receptor signaling pathway
101426457 (SRC)
04062 Chemokine signaling pathway
101426457 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
101426457 (SRC)
04915 Estrogen signaling pathway
101426457 (SRC)
04917 Prolactin signaling pathway
101426457 (SRC)
04921 Oxytocin signaling pathway
101426457 (SRC)
04926 Relaxin signaling pathway
101426457 (SRC)
04919 Thyroid hormone signaling pathway
101426457 (SRC)
09156 Nervous system
04727 GABAergic synapse
101426457 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101426457 (SRC)
09158 Development and regeneration
04360 Axon guidance
101426457 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101426457 (SRC)
05207 Chemical carcinogenesis - receptor activation
101426457 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
101426457 (SRC)
05203 Viral carcinogenesis
101426457 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
101426457 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
101426457 (SRC)
05168 Herpes simplex virus 1 infection
101426457 (SRC)
05163 Human cytomegalovirus infection
101426457 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
101426457 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
101426457 (SRC)
05152 Tuberculosis
101426457 (SRC)
05100 Bacterial invasion of epithelial cells
101426457 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101426457 (SRC)
05418 Fluid shear stress and atherosclerosis
101426457 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101426457 (SRC)
01522 Endocrine resistance
101426457 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:dnm01001]
101426457 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:dnm04131]
101426457 (SRC)
Enzymes [BR:dnm01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101426457 (SRC)
Protein kinases [BR:dnm01001]
Non-receptor tyrosine kinases
SRC family
101426457 (SRC)
Membrane trafficking [BR:dnm04131]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
101426457 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
101426457 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
101426457 (SRC)
Macropinocytosis
Kinases
101426457 (SRC)
|
SSDB |
|
Motif |
|
Other DBs |
|
LinkDB |
|
Position |
Unknown
|
AA seq |
570 aa
MEIPGPFPSEPLGDSSSGPPLASPARVEGQRRPSSKSKPKDASQRRRSLEPADSAHGGGA
FPAAQTPSKPASADGHRPGPAFAPAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVAL
YDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVAPSDSI
QAEEWYFGKITRRESERLLLNTENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYK
IRKLDSGGFYITSRTQFSSLQQLVAYSSEHADGLCHRLTTVCPTSKPQTQGLAKDAWEIP
RESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLV
QLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYV
HRDLRAANILVSENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS
DVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEP
EERPTFEYLQAFLEDYFTSTEPQYQPGENL |
NT seq |
1713 nt +upstreamnt +downstreamnt
atggagatccctggaccgtttccatctgagccgctgggcgactcctcctcggggcctccc
ctggcctccccagcccgggtggagggccagcggaggccgagcagcaagagcaagcccaag
gacgcgagccagcggcgccgcagcctggagcccgccgacagcgcgcacggcggcggcgcc
ttccccgccgcgcagacgcccagcaagcccgcctcggccgacggccaccgccccggcccc
gccttcgcgcccgcggccgccgagcccaagctgtttgggggcttcaactcctccgacacg
gtcacctccccgcagagggccgggccgctggctggtggtgtgaccacctttgtggctctc
tatgactacgagtcacggacagaaactgacctgtctttcaagaaaggggagcggctccag
attgtcaacaacacgaggaaggtggatgtcagagagggagactggtggctggcccactcg
ctcagcacgggacagacgggctacatccccagcaactacgtggcgccgtcggactccatc
caggcggaggagtggtacttcggtaagatcaccaggcgggagtcagagcggttgcttctc
aacacggagaacccacgagggactttcctagtgcgagaaagtgagaccacgaaaggcgcc
tactgcctctcggtgtcggatttcgacaacgccaagggcctcaacgtgaagcactacaag
atccgcaagctggacagcggcggcttctacatcacctcgcgcacgcagttcagcagcctg
cagcagctggtggcctactcctcagagcacgcggacggcctgtgccaccgcctcaccacc
gtgtgccccacgtcgaagccgcagacgcagggcctggccaaggacgcctgggagatcccc
cgggagtcgctgcggctggaggtcaagctgggccagggctgcttcggagaggtgtggatg
gggacctggaatggcaccaccagggtggccatcaagaccctgaagccaggcacgatgtct
ccggaggccttcctgcaggaagcccaggtcatgaagaaactgaggcacgagaagctggtg
cagctgtacgcggtggtgtccgaggagcccatctacatcgtcacggagtacatgagcaag
gggagtttgctggactttctcaagggagaaacaggcaaatacttgcgactgcctcagctg
gtggacatggctgctcagatcgcctcgggcatggcgtacgtggagcgcatgaactacgtc
caccgagacctgcgcgccgccaacatcctggtcagcgagaacctggtgtgcaaggtggct
gacttcgggctggctcggctcatcgaggacaacgagtacacggcccggcaaggtgccaaa
ttccccatcaagtggacggctccagaggccgccctctatggccggttcaccatcaagtcg
gatgtgtggtccttcgggatcctcctgacggagctcacgacaaagggacgggtgccctac
cccgggatggtgaaccgcgaggtgctggaccaggtggagcggggctaccggatgccctgc
ccgcccgagtgccccgagtccctgcacgacctcatgtgccagtgctggcggaaggagccg
gaggagcggcccaccttcgagtacctgcaggccttcctggaggactacttcacgtccacc
gagccccagtatcagcccggcgagaacctatag |