Dasypus novemcinctus (nine-banded armadillo): 101427687
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Entry
101427687 CDS
T07872
Symbol
LRRK2
Name
(RefSeq) LOW QUALITY PROTEIN: leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
dnm
Dasypus novemcinctus (nine-banded armadillo)
Pathway
dnm05012
Parkinson disease
dnm05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
dnm00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
101427687 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
101427687 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dnm01001
]
101427687 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dnm04131
]
101427687 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
dnm04147
]
101427687 (LRRK2)
Enzymes [BR:
dnm01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101427687 (LRRK2)
Protein kinases [BR:
dnm01001
]
Serine/threonine kinases: TKL group
LRRK family
101427687 (LRRK2)
Membrane trafficking [BR:
dnm04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
101427687 (LRRK2)
Exosome [BR:
dnm04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
101427687 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
LRR_4
COR
Ras
LRR_14
LRR_9
WD40_CDC20-Fz
Arf
Beta-prop_RSE1_2nd
Beta-prop_EML_2
Ank_2
T2SSE
LRR_6
nSTAND3
LRR_13
LRR_NXF1-5
G-alpha
Kdo
AAA_22
GTP_EFTU
TrwB_AAD_bind
AAA_7
WD40_WDHD1_1st
Beta-prop_RIG_2nd
ABC_tran
AAA_16
Septin
Beta-prop_WDR19_1st
MMR_HSR1
PduV-EutP
NACHT
MobB
cobW
AAA_29
TniB
FtsK_SpoIIIE
SRPRB
NB-ARC
ResIII
DUF2961
AAA_23
ARM_LIN_2nd
Arm
Motif
Other DBs
NCBI-GeneID:
101427687
NCBI-ProteinID:
XP_012385566
Ensembl:
ENSDNOG00000000920
LinkDB
All DBs
Position
Unknown
AA seq
2527 aa
AA seq
DB search
MASGKGPGRALDDEEALRKLVVRLNSVQEGKRVETLVQILEDVLVLAYADRASELFQGKN
VHMPLLVVLDSYMRVASVQQAGWSLLCKLIEICPATMQSLMGPQDIGHDWEVLAVHQLIL
KMLTVHNANINLATVGLKVLDLLLASGKITLLILDEENDIFLLIFDAMNTFSANEEIQKL
GCKALHVLFERVSEEQLTEFMENKDYMILLSTLKNFKDEEEIVFHILHCLHSLAIPCNNV
EVLMSGNVRCYNIVVEAMKAFPISEKIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKAV
KQYSENATLQISALSCLALLTETIFLNQDLEEKNEHQENDNEEEEDKLFWLEACYKALTW
HRKNKHVQEAACWALNNLLMYQNSLHKKIGDEDGQVPAHREVMLSMLMHSSSKEVFRASA
NALSTLLEQNVNFRKILLSKGIYLNVLELMQKHIHFPEVAESGCKMLNHLFEGSNTSLDT
MATVAPKILTVMKSHETSLSVQLEALRAILHFIVPGMPEESREDTELLHKLNMVKKQLFK
NDIHKLVLAVLNRFIGNPGIQKCGLKVISSIVHSPDALEMLSLEGAVDSVLHTLQMYPDD
QEIQRLGLSLIGCLITKKNFCIGTGHLLAKILVSSLQRFKDVADLQMNGFQTISAMLELS
VPFSKLLLHHSFDSVIFYQMSSSIMEQKDQQFLNLCCKCFARLVMDDELKSVMLERACDQ
NNSVMVECLLLLGADVNQTKESTSLICQVCEKESSPKLVELLLNSGAREQDVRKALAVSV
GKGDSQVISLLLRRLALDLANNSICLGGFCIGKIEPSWLGPLFPDKPSNLRKQTNIGSTL
ARMVLRYQTKSSVEEGAASGSDENFSEDVLDKFDEWTFIPDSSIDCVFGQSDDLDSEGSE
GSFLVKKKSNSISVGEFYRESALQRYSPNLRRHSNSLGPILDHEDLRKRRRKILSSDDSL
RSSKLQPHVRHSESMSSLASEREYITSLDLSANELRDIDALSQKCCITCHLEHLEKLELH
QNALTSFPPQLCETLKCLTHLDLHSNKFTSFPSYVLKMNCIANLDVSRNDIGPSIALDPG
VRCATLKQLNLSYNQLSSVPENLAQVAEKLEQLILEGNKLSGMCFSLRLKELKTLNLSKN
QISSLSEDFLEACPRVECFSARMNFLVAMPFLPSSITSLKLSQNKFTCIPEAILNLPHLR
ALDMSSNDIQYLPGPAHWKSLNLRELLFSCNQISILDLSEKAHAWSRVEKLHLSHNKLKE
IPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELHLNFDFKHIGYKAKDII
RFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDFGMQDATVGIDVKDWPIH
IRGKGKKDLILNVWDFAGREEFYSTHPHFLTQRALYLAVYDLSKGQAEVDAMKPWLFNIK
ARASSSPVILVGTHLDASDEKQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAK
LRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILWERRNVPIEFPVIDRKRLLQLVKE
NQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPRWLCKVMTEILTVKVEGFP
KHPKGIISRRDVEKFLSKKKRFPKNYMSQYFKLVEKFQIALPIGEEYLLVPSSLSDHRPV
IELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIY
LNWSPEAYCLVGSEVFDNHLDSFLKITVPSGRKGCILLGQVVDHIDSLMEEWFPGLLEID
ICGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDL
ILADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQ
ELVVLCHLHHPSLISLLAAGIRPRMLVMELAPKGSLDRLLQQDKASLTRTLQHRIALHVA
DGLRYLHSAMIIYRDLKPHNVLLFTPYPNAAIIAKIADYGIAQYCCRMGIKTCEGTPGFR
APEVARGNVIYNQQADVYSFGLLLYDILTTGGRIIEGLKFPNEFDELAIQGKLPHPVKEY
GCAPWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELICLMRSLLIPKNVIVECMVANN
HSKNASIWLGSGHPDQGQLSFLDLNTEAYTSEEVTDSRILCMALVHLPVEKESWVVCGTQ
SGTLLVISTEDGKRRHALEKMSDSVTCLYCHSFSKLSKQKNFLLVGTADGNLAIFEDKTV
KCKGAAPLKILNIGNVSTPLMCLSESMNSNEKNLMWGGCGTKIFSFSSDFTIQKLIETRT
SQLFSYASFSDSNIIAVVVDTALYIAKKNSPVVEVWDKKTEKLCELIDCVHFLKEEMVKA
SKESKHKMSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRIIRIIHNFCDSIRVMRT
AQLGSLKNVMLVLGYRRKNTEGAQHQKEIQSCLSVWDINLPHEVQNLEKHIEVRKELAEK
MRRISVE
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggccagcggcaagggcccggggcgcgcgctggacgacgaggaggccctgcggaagctg
gtggtcaggctgaacagcgtgcaggagggaaagcgggtggagacgctcgtgcagatcctg
gaggacgtgctggtgctcgcctacgccgaccgcgcctccgagttatttcagggcaaaaat
gtccacatgcctctcttggttgtcttggactcgtacatgcgagtggcgagcgtgcagcag
gcaggttggtcacttctatgcaagttaatcgagatctgtccagctacaatgcaaagctta
atggggccccaggatattggacatgattgggaagtccttgctgttcaccaactgattctt
aaaatgctaacagttcataatgccaatataaacctggcaacagttgggctgaaggtctta
gatctcctcctagcttcaggtaaaatcactttgctgatattggatgaagaaaatgatatt
ttcttgttaatttttgatgctatgaacacattttcagccaatgaagaaatccagaaactt
ggatgcaaagccttacatgttctttttgagagagtttcagaggagcaactgactgaattt
atggagaataaagattatatgatattgctgagtacattaaaaaattttaaagatgaggag
gaaattgtgtttcatatacttcactgtttacattccttagcgattccttgcaataatgtt
gaagttctcatgagtggcaatgtgaggtgttacaatattgtggtggaagccatgaaagcc
ttccctatcagtgaaaaaattcaggaagtgagttgctgcttgctccataggctgacatta
ggtaacttttttaatattttggtattaaatgaggtacatgagtttgtggtgaaagctgtg
aagcagtattcagagaacgcaaccttgcaaatctcagcactcagctgtttagcgctcctc
actgagaccattttcctaaatcaagatcttgaggaaaaaaatgagcatcaggagaatgat
aatgaagaggaagaagataaattgttttggctggaagcctgttacaaagcattaacgtgg
cataggaaaaacaagcatgtacaggaggctgcatgctgggcattaaataatctccttatg
taccaaaacagtttacacaagaagattggagacgaagatggccaagtcccagctcatagg
gaagtgatgctttccatgctgatgcattcctcatccaaagaagtgttccgggcctctgca
aatgcattgtcaactctgttagaacaaaatgttaatttcagaaaaatcctgttatcaaaa
ggaatatatctgaatgtattggagttaatgcagaagcatatacattttcctgaagtggct
gaaagtggctgtaaaatgctaaatcatctttttgaaggaagtaacacttccctggataca
atggccacggtggcccccaaaatactaacagttatgaaaagccacgaaacatcactttct
gtgcagctggaggcgcttcgagctattttacattttatagttccaggcatgccagaagaa
tcgagggaggatactgagttactacataagctaaacatggttaaaaaacagttgttcaag
aatgatattcacaagctggtcctagcggttttgaacaggttcattggaaatcctgggatt
cagaaatgtggattaaaagtaatttcttctatagtacattctcctgatgcattagagatg
ttatcactggaaggtgctgttgattctgtacttcacacactgcagatgtatccagatgac
caagaaattcaacgtcttggtttaagtcttataggatgcttgattacaaagaagaatttt
tgcataggaactgggcatctactggcaaaaattctggtttccagtttgcaacgatttaag
gatgttgctgatttacagatgaatggatttcagacaatctcggcgatgcttgaattgtca
gttcctttttccaagctgttattgcatcactcatttgattcagtaatattctaccagatg
tcttccagtatcatggagcaaaaagatcaacagtttctaaacctttgttgcaagtgcttt
gcaagattagttatggacgatgaattaaaaagtgtgatgctagagcgagcctgtgatcag
aataacagcgtcatggttgagtgcttacttctgttgggagctgatgttaatcaaacgaag
gagtccacttctttaatttgtcaggtatgcgagaaagagagcagtcccaaattggtggaa
ctgttactgaatagtggcgcccgtgaacaagacgtccggaaagcgctggctgtcagcgtt
gggaagggtgacagccaagtcatcagcttgcttttgagaaggcttgccctggacctggcc
aataacagcatttgccttggaggattttgtataggaaaaatcgaaccttcctggcttggt
cccttatttccggataagccatctaatttaagaaaacaaacaaatattggatctacccta
gcaagaatggtgctcagatatcagacgaaaagttctgtggaagaaggagcagcctcgggc
agcgatgagaacttttctgaagatgtcctggataagtttgatgaatggaccttcattcct
gattcttctatagattgtgtgtttggtcagagtgatgatctggatagtgaaggaagtgaa
ggctcatttcttgtgaaaaagaaatcaaattcaattagtgtgggagaattttaccgagag
tctgccttgcagcgttactcaccaaatttgcgaaggcattccaattcattgggtcctata
cttgatcatgaagatttacggaagcgaagaagaaaaatattatcttcagatgattcactc
aggtcatcaaaacttcaaccccatgtaaggcattcagagagcatgtcttccctggcctct
gagagagaatacattacatcactagatctttcagcaaatgaactaagagatattgatgcc
ctaagccagaaatgctgtataacttgtcatttggaacatcttgaaaagctggaacttcat
cagaacgcactcacgagctttccaccacagctatgtgaaactctgaagtgtttgacacat
ttggacttgcacagtaataaatttacatcatttccgtcttacgtgttgaaaatgaattgc
attgccaaccttgacgtttctagaaatgacattggaccctcgatagccttggatcctggg
gtgaggtgtgcgaccctgaagcagcttaacctgtcgtataatcagctgtcttctgtacct
gagaatctcgcccaggtggcagagaaactggaacagctcattttagaaggaaataagtta
tcaggaatgtgtttttccctgaggctgaaggaactgaagacgttaaaccttagtaaaaac
cagatttcatccctatctgaagactttcttgaggcttgtcctagagtggaatgtttcagt
gccagaatgaattttcttgttgctatgcccttcttgccatcttccataacaagcctaaag
ttatctcaaaacaaatttacatgtattccggaagcaattttaaatcttccacacttgcgg
gccttagatatgagcagcaacgacattcagtatctgccaggtcctgcgcactggaaatct
ttgaacctaagggaacttttgtttagctgtaatcagatcagcattttggacttgagtgaa
aaagcacatgcatggtctagggtagagaaacttcatctttctcataataaattaaaagag
attcctcctgagattggctgtcttgaaaatctgacatctcttgatgttagttacaacttg
gaactgagatcctttcccaatgaaatgggtaaattgagcaaaatatgggatcttcctttg
gatgaactgcatcttaattttgattttaaacatataggatataaagccaaagacatcata
aggtttcttcagcagcggttaaaaaaggctgtgccttataaccgaatgaagctcatgatt
gtaggaaatactggaagtggtaaaaccaccttactgcagcaattaatgaaaaccaaaaaa
tcagattttggaatgcaagatgccactgtcggcatagatgtgaaagactggcctatccat
ataagaggcaaagggaagaaagacctgattctaaatgtgtgggattttgcaggtcgtgag
gaattctacagcactcatccgcacttcctgacccagagagcgttatacctggccgtctac
gacctcagcaaggggcaagccgaggtggatgccatgaagccttggctcttcaatataaag
gctcgtgcttcttcttccccggtgattctcgttggcacacatctggatgcttccgacgag
aagcagcgcaaagcctgcatcagtaaaatcaccaaggaactcttgaacaagagggggttc
cccgcaatacgggattaccactttgtgaatgccaccgaggagtcggatgctttggcaaaa
cttcggaaaaccataataaacgagagccttaatttcaagatccgagaccagcctgtcgtt
gggcagctgattccagactgctatgttgaacttgagaaaatcattttatgggagcgtaga
aatgtgccaattgaatttcctgtaattgaccggaaacgattattacagctagtgaaagaa
aatcagctgcagttagatgaaaatgagcttcctcatgcagttcacttcctaaatgaatca
ggggtccttcttcattttcaagacccagcactgcagttgagtgacttatatttcgtagaa
cccaggtggctttgcaaagtcatgacagagattttgacagtgaaagtggaaggctttccg
aagcatcctaaggggatcatttcacgtagagatgtggaaaaattcctttcaaagaaaaag
agatttccgaagaactacatgtcacagtactttaaactcgtagaaaaattccagattgcc
ttgccaataggagaagaatatttactggttccaagcagtttgtctgaccacagacccgtg
attgagctcccccactgtgagaactccgagatcatcattcggctctatgaaatgccttat
tttccaatgggattttggtcaagattaatcaatcgattactcgaaatttcaccttacatg
ctttcaggaagagaacgagcacttcgcccaaacagaatgtactggcgacaaggcatctac
ttgaattggtctccagaagcttattgtctcgtaggatctgaagtcttcgacaatcacctg
gatagtttcttaaaaattacagttccttctggtagaaaaggttgtattcttttgggccaa
gttgtggatcacattgattctctcatggaagaatggtttcctgggctcctggagatcgac
atttgtggtgaaggagagactctgctgaagaagtgggcattgtatagttttaatgatggt
gaagagcatcaaaaaattttacttgatgacttgatgaagaaagcagaagaaggagacctc
ctagtaaatccagatcaaccaaggctcaccatcccaatatctcagattgctcctgatttg
attttggctgacctgcctagaaatattatgttgaataatgatgagctggaatttgaacaa
gccccagaatttctcttaggtgatggcagttttggatcagtttatcgagcagcttatgaa
ggagaagaagtggctgtgaagatttttaataaacatacatcgcttagactgttaagacaa
gagcttgtggtgctttgccacctccaccacccgagcttgatctctttgctggctgccggg
attcgtcctcggatgctggtgatggaattggctcccaagggctccctggaccgcctgctg
cagcaggacaaggccagcctcaccagaaccctgcagcacaggatcgccctgcacgtggct
gacggtttgaggtatctccactcagccatgattatataccgtgacctgaagcctcacaac
gtgctgcttttcaccccgtatcccaatgctgctatcatcgcaaagatcgctgactacggg
atcgctcagtactgctgcaggatgggcatcaaaacgtgcgagggcacaccagggtttcgc
gcacctgaggttgccagaggaaatgttatttataaccagcaggctgatgtttattcattt
ggtttactgctctatgacattttgacaactggaggtcgaatcatagagggattgaaattt
ccaaatgagtttgatgaattggcaatacaaggaaaattacctcatccagttaaagaatat
ggttgtgccccatggcctatggttgagaagttaattaaaaagtgtttgaaagaaaatcct
caagaaagacctacttctgcccaggtctttgacattttgaattcagctgagttaatctgc
ctgatgagatctcttttaatacctaaaaacgttattgtcgagtgtatggttgccaataat
catagcaagaacgcaagcatctggctgggctccgggcatcctgaccaagggcagctctcc
tttcttgatttaaatactgaagcatacacttctgaggaagtcactgatagtagaattttg
tgcatggctttggtgcatcttcctgtggaaaaggaaagttgggttgtgtgtggcacccag
tctggcactctcctggtcatcagtacagaagacgggaaaaggagacacgcacttgagaag
atgagtgattccgtcacttgtttgtattgccattccttttccaagctaagcaagcaaaaa
aattttcttctggtgggaactgctgatggcaatttagccatttttgaagacaaaactgtt
aagtgtaaaggagctgctcctttgaagatactcaatataggaaatgtcagcactccactg
atgtgtctgagtgagtccatgaattcaaatgaaaaaaacttaatgtggggaggatgtggc
acgaagattttctcattttctagtgatttcaccattcagaaactcattgagacaaggaca
agtcagctgttttcttatgcatctttcagtgattccaacatcatagcagtggtggtcgac
acagctctctatattgctaagaaaaacagccctgttgtggaagtatgggataagaaaact
gagaaactctgtgaactaatagactgtgtgcactttttaaaggaagaaatggtgaaagcg
agcaaggaatcaaaacataaaatgtcttattctgggagagtgaaaactctctgcctgcag
aagaacactgctctctggataggaaccggaggcggccatattttactgcttgacctttca
actcgtcgaattatacgcataattcacaacttctgtgattccatcagagtcatgaggaca
gcacagttaggaagccttaagaatgtcatgctggttttggggtataggcggaaaaatact
gaaggtgcacaacaccaaaaagagatacaatcttgcttgtctgtctgggacatcaatctt
ccacacgaagtgcaaaatttagaaaaacacattgaagtgagaaaagagttagctgaaaaa
atgagaagaatatctgttgagtaa
DBGET
integrated database retrieval system
