| Entry |
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| Symbol |
PDGFRA
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| Name |
(RefSeq) LOW QUALITY PROTEIN: platelet-derived growth factor receptor alpha
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| KO |
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| Organism |
dnm Dasypus novemcinctus (nine-banded armadillo)
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| Pathway |
| dnm01521 | EGFR tyrosine kinase inhibitor resistance |
| dnm04072 | Phospholipase D signaling pathway |
| dnm04810 | Regulation of actin cytoskeleton |
| dnm05163 | Human cytomegalovirus infection |
| dnm05230 | Central carbon metabolism in cancer |
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| Brite |
KEGG Orthology (KO) [BR:dnm00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101428297 (PDGFRA)
04014 Ras signaling pathway
101428297 (PDGFRA)
04015 Rap1 signaling pathway
101428297 (PDGFRA)
04630 JAK-STAT signaling pathway
101428297 (PDGFRA)
04020 Calcium signaling pathway
101428297 (PDGFRA)
04072 Phospholipase D signaling pathway
101428297 (PDGFRA)
04151 PI3K-Akt signaling pathway
101428297 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101428297 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101428297 (PDGFRA)
04540 Gap junction
101428297 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101428297 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101428297 (PDGFRA)
05206 MicroRNAs in cancer
101428297 (PDGFRA)
05230 Central carbon metabolism in cancer
101428297 (PDGFRA)
05231 Choline metabolism in cancer
101428297 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
101428297 (PDGFRA)
05218 Melanoma
101428297 (PDGFRA)
05215 Prostate cancer
101428297 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
101428297 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101428297 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:dnm01001]
101428297 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:dnm04090]
101428297 (PDGFRA)
Enzymes [BR:dnm01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101428297 (PDGFRA)
Protein kinases [BR:dnm01001]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
101428297 (PDGFRA)
CD molecules [BR:dnm04090]
Proteins
101428297 (PDGFRA)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1289 aa
MLGGGSRGVLPSSWQPVLEGDRFLMNVFIPRRWFGGTERQLAGWSAAGGPGKAKSAERGA
GRGCGAAGRGRREGVGWRQPDLGSLTGTHGAGGARVITGRRSARCEPGPDSAHLRWLPDE
QTRPGLGRGFGVLPSGLPGQGVEPLLQTPGLCYWPVPATRKKRGSRQEKCRTSLGKLGAA
WNRGTWFQFSRTMWPSRRAFLFLGCLLTGPGLILCQLSLPSILPNENEKVVQLNSSFSLR
CFGESEVSWQYPLSEEENPNVEIRSEENNSGLFVTVLDVVSASAAHTGLYTCYYNHTQTE
ENEIEGRHIYIYVPDPDVAFAPLGMTDYLVIVEDDDSAIIPCRTTDPDTPVTLRNSDGVV
HASYDSRQGFNGTFSVGPYVCEATINGRTFQTIPFNVYALKATSKLDLEMEALKTVYKAG
ETIVVTCAVFNNEVVDLQWTYPGEVRGKGITMLDEIKVPLIKLLYTLTIPEATVKDSGDY
ECAARQATREVKEMKKVTIAVHEKGFIEIKPNFSQLEAVNLHEVKHFVVDVQAYPPPKIS
WLKDNLTLIENLTEITTDVEKTQEIRYRSKLKLIRAKEEDSGHYTIVVKNEDDEKRYTFE
LLTQVPASILDLADDHHGPTGAQIVRCTAGGTPLPDIEWMICKDIKKCNNETSWTILANN
VSNILTEIHPRDRNTMEGQVTFMKVEETIAVRCLTKNLLGAENRELKLVAPTLRSELTVA
AAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEF
PRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIM
THLGPHLNIVNLLGACTKSGRLLNLEVNVFTEHLXLXKLLNQVFNLPLSIPSYTSEHPEK
PKKELDIFGLNPTDESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRS
LYDRPASYKKKSMLDSEVKNLLSDNNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLA
ARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWS
YGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKR
PSFYHLSEIVETLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEDDKL
KGWEGGLDEQRLSADSGYIIPLPDIDPVPEDEDLGKRNRHSSQTSEESAIETGSSSSTFI
KREDETIEDIDMMDDIGIYSSDLVEDSFL |
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| NT seq |
3870 nt +upstreamnt +downstreamnt
atgctggggggtgggagcagaggtgtgttgccctcttcttggcagccggtcctggaaggc
gacaggtttttaatgaatgttttcattcctcgccggtggtttggtgggaccgagcggcag
ctcgcggggtggagcgcggctgggggacccgggaaagcaaagagcgccgagaggggcgcg
ggcaggggctgcggggctgcggggcgggggaggcgtgaaggggtcggctggaggcagccg
gacctcgggagcctgacgggtacacatggcgccggcggagcgcgcgtaattactggacgg
cgcagcgcccggtgcgagccggggccagactcagcacatctgcggtggctgccagacgag
cagacaagacctgggctcgggcgagggtttggggtgcttcccagcggtttgcctggtcag
ggagtggaaccactgctgcaaaccccggggctctgctactggccagtcccggccacaagg
aagaagagaggaagtcgccaggaaaagtgccgaacttctttggggaaattaggggcggct
tggaacagaggaacttggttccagttttccagaacgatgtggccttctcgccgggcattc
ctgtttctaggctgcctcctcacaggaccgggcctaatactctgccagctttcattaccc
tcgatccttccaaatgaaaatgaaaaggttgtgcagctgaattcatccttttctctgaga
tgctttggggagagtgaagtgagctggcagtaccccctgtctgaagaagagaaccccaat
gtagagatcagaagtgaggaaaacaacagtggcctttttgtgaccgtgctggatgtggtc
agtgcctcggcggcccacacaggactgtacacttgctattacaaccacactcagacagaa
gaaaatgagatcgaaggcagacacatttatatctatgtgccagacccagatgtagccttt
gcgcccctaggaatgacggattatttggtcattgtggaggatgatgattctgctatcata
ccctgccgcacgactgatcctgacactccggtgaccttacgcaacagcgatggggtggta
cacgcctcctatgacagcagacagggctttaacggaaccttctctgtggggccctatgtc
tgtgaggccaccatcaacgggaggacgttccagaccatccccttcaatgtctatgcctta
aaagcaacatccaaacttgatctagaaatggaagcgctaaaaactgtatataaggcgggg
gagacgattgtggtcacgtgcgcagtctttaataatgaggtggttgaccttcagtggact
tatccgggcgaagtgagaggcaaaggcatcacaatgctcgatgaaatcaaagttccgctc
attaagttgttgtacaccttgacgatccccgaggccacggtcaaggacagtggagattac
gaatgtgcagcccgccaggccaccagggaggtcaaagaaatgaagaaagtcaccattgct
gtccacgagaaagggttcattgaaatcaaacccaacttcagccagttggaagccgtcaac
ctgcatgaagtcaaacattttgtggtggacgtgcaggcctacccccctcccaagatatcc
tggctgaaggacaatctgactctgattgaaaatctaactgagatcacgactgacgtagaa
aagactcaggaaataaggtatcgaagcaaattaaagttgatccgtgctaaggaagaagac
agtggccattatactattgtagttaaaaatgaagatgatgagaagaggtatacttttgaa
ttattaactcaagttcccgcatccattctggacttggctgatgaccaccacggccccacg
ggggcacagattgtgcggtgcacagctggaggaactcctcttcccgatattgagtggatg
atctgcaaggatattaaaaagtgtaataatgaaacttcatggacaattttggccaacaac
gtctcaaacatcctcacagagatccacccccgagacaggaataccatggagggccaagtg
actttcatgaaagtggaagagaccattgcagttcggtgcctgaccaagaatcttcttggg
gctgagaaccgggaactgaagctggtggctcccactctgcgttctgaactcactgtggcc
gctgccgtcctggtgctgttggtgatcgtgatcatctcccttattgtcctggttgtcatt
tggaaacagaaaccaaggtatgaaattcgctggagggtcattgaatcaatcagccctgat
ggacacgaatatatttatgtcgacccgatgcagctgccttatgactcgagatgggagttt
ccaagagatggactagtgcttggtcgtatccttggatctggtgcatttgggaaagtggtt
gaaggaactgcctatggattaagccggtcccagcctgtcatgaaagtagcagtgaagatg
ctaaaacccacagccagatccagtgaaaaacaagctctgatgtctgaactaaagataatg
actcacctggggccacatctaaacattgtaaacttgctgggagcctgtacaaaatcaggt
agacttttgaatctggaagtgaatgttttcacagaacacctatagttgtgaaaactgttg
aaccaggtttttaatctcccactgtccatccccagttataccagtgaacatccagagaag
ccaaagaaagagctggacatctttggattgaaccccactgatgaaagcacacggagttat
gttattttatcttttgagaacaatggtgactacatggacatgaagcaagccgacaccacc
caatatgtccccatgctagaaaggaaagaggtttccaaatattcggatatccagagatcg
ctgtatgatcgcccagcctcatataagaagaaatctatgttagactccgaagtcaagaac
ctcctttcggacaataactcagaaggccttactttgttggatttgttaagcttcacctat
caagttgcccgaggaatggagtttttggcttcgaaaaattgcgtccaccgggacctggct
gctcgcaacgtcctcctggctcaagggaaaatcgtgaagatctgtgactttggcctggcc
agggatatcatgcatgattccaactacgtgtcaaaaggcagcacctttcttcctgtgaag
tggatggctcctgagagcatcttcgacaacctctacaccaccttgagtgacgtctggtct
tacggcattctgctctgggagatcttttcccttggtggcacaccctaccctggcatgatg
gtggattctactttttacaataagatcaagagtgggtaccggatggccaagcccgaccac
gccaccagtgaagtctacgaaatcatggtgaagtgctggaacagtgagccagagaagaga
ccttccttttaccacctgagtgaaattgtggagacgctgttgcctgggcaatataaaaag
agttatgagaaaatccacctggacttcctgaagagtgaccaccccgccgtggcacgcatg
cgtgtggactctgacaacgcgtacattggcgtcacctacaaaaacgaggacgacaagctc
aagggctgggagggtggccttgatgagcagagactgagcgccgacagtggctacatcatt
cccctgcctgacatcgaccctgttccggaggacgaagacctgggcaaaaggaacagacac
agctcacagacctctgaagagagtgctattgagacaggatccagcagttctaccttcatc
aagagagaggatgagaccattgaggacatcgacatgatggatgacattggcatatactcc
tcagacctggtggaggacagtttcctgtaa |
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