| Entry |
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| Symbol |
CFTR
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| Name |
(RefSeq) cystic fibrosis transmembrane conductance regulator
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| KO |
| K05031 | cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6] |
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| Organism |
dnm Dasypus novemcinctus (nine-banded armadillo)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:dnm00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
101433838 (CFTR)
09132 Signal transduction
04024 cAMP signaling pathway
101433838 (CFTR)
04152 AMPK signaling pathway
101433838 (CFTR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
101433838 (CFTR)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
101433838 (CFTR)
04972 Pancreatic secretion
101433838 (CFTR)
04976 Bile secretion
101433838 (CFTR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:dnm02000]
101433838 (CFTR)
Enzymes [BR:dnm01000]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
101433838 (CFTR)
Transporters [BR:dnm02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
101433838 (CFTR)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1567 aa
MHQTRAERSGYTRDTFSFSFQNAPCNASHESDRDLGKKEKGSGQWPVAGSACGATRRVGA
PRGFSGLAPHLRGVPSAHQRRRLDLCTAAATSLPPAGWSGAGRWTRPILRKGYRQRLELS
DIYQIPSADSADNLSEKLEREWDRELASKKNPKLINALRRCFFWRFTFYGIILYLGEVTK
AVQPLLLGRIIASYDPDNKVERSIAIYLAVGLCLLFVVRTLLLHPAIFGLHHIGMQMRIA
MFSLIYKKTLKLSSRVLDKISIGQLVSLLSNNLNKFDEGLALAHFVWIAPLQVTLLMGLL
WDLLQASAFSGLGVLIILACFQAGFGRMMMKYRDQRAGKINERLVITSEMIENIQSVKAY
CWEEALEKMIENFRQSELRLTRKAAYVRYFNSSAFFFSGFFVVFLSVLPYALIKGIILRK
IFTTISFCIVLRMAVTRQFPWAVQTWYDSLGAINKIQDFLQKQEYKSLEYNLTTTDVVME
TVTAFWEERFGELFEKAKQNNNNRKISNVDNSLFFSNFSLLGTPVLKDINFKIERGQLLA
VAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIMPGTIKENIIFGVCYDEY
RYRSVIKACQLVEDISKFAEKDNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPF
GYLDVLTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQN
LRPDFSSKLMGYDSFDQFSAERRNSIITETLRRFSLEGDAAHSWNETKKQSFKQTGEFGE
KRKNSILNPINSLRRISITQKTPLPMNGIDEDSGETLERMMSLVPDCEQGEGILPRSNLI
NTGPTLQRGRRQSVLNLMTHSSGNQGQNIHRRTTAFTRKMSLAPQANLVEMDIYSRRLSQ
DSGLEISEEINEEDLKECFLDDVESIPAVTTWNTYLRYITVHKRLIFVLIWCFVVFLIEV
AASLVLLCLLSKVSPEDKGNTTKSANDSSAVIITSTSSFYFLYIYVGVADTFLALGLFRG
LPLVHTLITVSKILHHKMLHSVLQAPMSTLNTLKAGGILNRFSKDIAILDDLLPLTIFDF
IQLLLIVIGAVAVVSILKPYIFLATVPVIVAFVLLRAYFLHTSQQLKQLESEARSPIFTH
LVTSLKGLWTLRAFGRQPYFEALFHKALNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAV
TFISILTTGEGEGTVGIILTLAMNIMSTLQWAVNSSIDVDSLMRSVSRVFKFVDMPTEEN
KPTKSIKLPKDGQLSKVMIIENQHVKKDDIWPSGGQMTVKDLTAKYIDGGNAILENISFS
ISPGQRVGLLGRTGSGKSTLLSAFLRLLNTKGEIQIDGVSWDSITLQEWRKAFGVIPQKV
FIFSGTFRKNLDPYGQWSDQEIWKVADEVGLRSVIEQFPGKLDFVLVDGGYVLSHGHKQL
MCLARSVLSKAKILLLDEPSAHLDPITYQIIRRTLKQAFADCTVILCEHRIEAMLECQRF
LVIEENKVRQYDSIQRLLSEKSLFRQAISPSDRVKLFPHQNSGKHKSRSKITALKEETEE
EVQDTRL |
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| NT seq |
4704 nt +upstreamnt +downstreamnt
atgcatcagacgcgcgcggaacgttccggctacacaagagacacattttcgttctctttt
caaaatgcaccttgcaacgcgtcacacgaatccgaccgagaccttggaaaaaaggagaaa
ggctcagggcagtggccggtggcgggttctgcgtgcggcgccacgcggcgcgtaggagcg
cccaggggtttctccgggctggctccccacctgcggggggttccttcggcccaccagcgt
cggagactggatctctgcacagcggccgcgacttctctcccacctgcgggctggtctgga
gctggacgctggaccagaccaattttgaggaaagggtacagacagcgcctggaattgtca
gacatataccaaataccttctgctgattctgctgacaatctatctgaaaaattggaaaga
gaatgggacagagagctggcttcaaagaaaaatcccaaactcattaatgctcttcgacga
tgctttttctggagatttacgttctatgggattatattgtatttaggggaagtcaccaaa
gctgtgcagcctctcttactgggaagaattatagcttcctatgatccagataacaaggtg
gaacgctccattgcaatttaccttgccgttggcttgtgccttctgttcgttgtgaggacg
ctgctcctgcacccagccatttttggacttcatcacattggaatgcagatgagaatagcg
atgtttagcttgatttataagaagaccttaaaactgtcaagccgtgttttagataaaata
agtattggacaacttgttagtctcctttccaacaacctgaacaaatttgatgaaggccta
gcattagcacatttcgtgtggatcgctcctttacaagtgacgctgctgatgggactgctg
tgggatttgctccaggcctctgccttcagtggacttggtgtcctgatcatcctcgcctgt
tttcaagctgggtttgggagaatgatgatgaaatacagagatcagagagctggaaagatc
aatgaaagacttgtgatcacctcagaaatgattgaaaatattcagtctgtcaaggcatac
tgctgggaggaggcactggaaaaaatgattgaaaatttcagacagtcggaactgagactg
actcggaaggcagcctatgtgagatacttcaacagctcagctttcttcttctcagggttt
tttgtagtgtttttatctgtgcttccctatgcactgatcaaaggaatcatccttcgcaaa
atattcacaaccatctcattctgcattgttctgcgcatggcagtcacacggcaattcccc
tgggctgttcaaacatggtatgactcacttggagcaataaacaaaatacaggacttctta
caaaaacaagagtataagtcattggagtataacttaacaactacagatgtagtgatggag
actgtaacagccttctgggaggagcgatttggagaattatttgagaaagcaaaacaaaat
aataacaacagaaaaatttccaatgttgataatagcctcttcttcagtaacttctcactt
cttggcactcctgtccttaaagatattaatttcaagatagaaagaggacaattattggca
gttgctggatctactggagcaggcaagacttcccttttaatgatgattatgggagaacta
gagccctcagagggtaaaattaagcacagtgggagaatttcgttctgctctcagttttcc
tggatcatgcctggtaccattaaagaaaacatcatctttggtgtttgttatgatgagtat
agatacaggagtgtcatcaaagcctgccaactagtggaggacatctccaagtttgcagag
aaagacaatacagttcttggagaaggtgggatcacattgagtggaggtcaacgagcaaga
atttctttagcaagagcagtatacaaagacgctgatttgtacctcttagactctcctttt
ggatacctagatgttttaacagaaaaagaaatatttgaaagctgtgtctgtaaattgatg
gctaacaaaactaggattttggttacttccaaaatggaacatttaaagaaagctgacaaa
atactaattttacatgaaggtagcagctatttttatggaacattttctgaactacaaaat
ctacggccagacttcagctcaaagctcatgggatatgattcttttgaccagtttagtgca
gaaagaagaaattcaattataactgaaaccctgcggcgtttttcattagaaggagatgct
gctcattcctggaatgaaacaaaaaaacaatcttttaaacagactggagagtttggtgaa
aaaagaaagaactctattctcaatccaatcaactccctaagaagaatttcaataacacaa
aagactccattgccaatgaatggcattgatgaggattctggtgaaactttagagagaatg
atgtccttagttccagattgtgagcagggagaaggtatccttcctcggagtaacttgatt
aacactggccccacgcttcagagaggaagaaggcaatctgttctgaacttgatgacacac
tcctctggcaaccaagggcaaaacattcacaggaggacaacagcattcacacgaaaaatg
tcactggcccctcaggctaacttagttgaaatggacatatattcaagacgattatctcaa
gacagtggtttggaaataagtgaagaaattaatgaagaagatttaaaggagtgctttttg
gatgatgtggagagcattccagcagtgaccacatggaacacatatcttcgatacattact
gtccataagagattaatttttgtgctaatttggtgctttgttgtttttctgattgaggtg
gctgcttctttggttctgttgtgtctacttagtaaagtatctcctgaagacaaagggaat
actactaagagtgccaatgacagctctgcagtgatcatcaccagcaccagctcgttttac
tttttgtacatttacgtgggagtagctgacactttcctcgctctgggactcttcaggggt
ttaccactggtgcacactctaattacagtgtcgaaaattttacaccacaaaatgttacat
tctgttcttcaagcacctatgtcaaccttaaacacattaaaagcaggtgggatacttaat
agattctccaaagatatagcaattttggatgatcttctgcctcttaccatatttgacttc
atccagctgctgttaattgtgattggtgctgtagccgtagtctcgattttaaaaccctac
atcttcctagcaacagtgcctgtgatagttgcgtttgttctattgagagcatacttcctt
cacacctcacagcaactcaaacaactggaatctgaagccagaagcccaattttcactcat
cttgttacaagtttaaaaggactgtggacacttcgtgcctttggacgtcagccttacttt
gaagctctgttccacaaagctctgaatttgcatactgccaactggttcctgtacctatca
acactacgctggttccaaatgaggatagaaatgatttttgtcatcttcttcattgctgtt
accttcatttccattttaacaacaggtgaaggagaaggaacagttggtattattctaact
ttagccatgaatatcatgagtacattgcagtgggctgtgaactccagcatagatgtggat
agtttgatgcgatctgtgagccgagtctttaagtttgttgacatgccaacagaagaaaat
aagcctaccaaatcaatcaaactgcccaaggatggccagctttccaaagtcatgattatt
gagaatcagcacgtgaagaaagatgacatctggccctctgggggccaaatgactgtcaaa
gaccttacagcaaaatatatagatggtgggaatgccatattagagaacatttcattctca
ataagtcctggccagagggtgggcctcttgggaagaactggatcagggaaaagcactttg
ttgtcagcttttttgagactgctaaacactaagggagaaattcagattgatggcgtgtct
tgggattcaataactttgcaagagtggaggaaagcctttggagtgataccacagaaagta
tttatcttttctggaacatttagaaaaaacttggatccctatggacaatggagtgatcaa
gaaatatggaaagttgctgatgaggttggacttaggtctgtaatagaacagtttcctggg
aagcttgattttgtccttgtggatgggggttatgttctaagccatggtcacaaacagttg
atgtgcttggccagatctgttcttagtaaagcaaagatcttgctgctagatgaacccagt
gctcatttggatccaataacttaccaaatcattcgaagaacgctaaaacaagcatttgct
gattgcacagtaatcctctgtgagcacaggatagaagcaatgttggaatgtcaacgattt
ttggtcatagaggagaacaaagtgcggcagtacgattccatccagaggctgctgagcgag
aagagcctcttccggcaggctatcagcccctcagaccgtgtgaagctcttcccccaccag
aactctggcaagcacaagtctcgatccaaaatcacagctctaaaggaggagacagaagaa
gaggtgcaagacacaagactttag |
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