KEGG   Dasypus novemcinctus (nine-banded armadillo): 101439506
Entry
101439506         CDS       T07872                                 
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X2
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
dnm  Dasypus novemcinctus (nine-banded armadillo)
Pathway
dnm04022  cGMP-PKG signaling pathway
dnm04024  cAMP signaling pathway
dnm04062  Chemokine signaling pathway
dnm04071  Sphingolipid signaling pathway
dnm04270  Vascular smooth muscle contraction
dnm04350  TGF-beta signaling pathway
dnm04360  Axon guidance
dnm04510  Focal adhesion
dnm04520  Adherens junction
dnm04530  Tight junction
dnm04611  Platelet activation
dnm04670  Leukocyte transendothelial migration
dnm04810  Regulation of actin cytoskeleton
dnm04921  Oxytocin signaling pathway
dnm05135  Yersinia infection
dnm05163  Human cytomegalovirus infection
dnm05200  Pathways in cancer
dnm05205  Proteoglycans in cancer
dnm05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:dnm00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    101439506 (ROCK1)
   04071 Sphingolipid signaling pathway
    101439506 (ROCK1)
   04024 cAMP signaling pathway
    101439506 (ROCK1)
   04022 cGMP-PKG signaling pathway
    101439506 (ROCK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101439506 (ROCK1)
   04520 Adherens junction
    101439506 (ROCK1)
   04530 Tight junction
    101439506 (ROCK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101439506 (ROCK1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101439506 (ROCK1)
   04670 Leukocyte transendothelial migration
    101439506 (ROCK1)
   04062 Chemokine signaling pathway
    101439506 (ROCK1)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    101439506 (ROCK1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    101439506 (ROCK1)
  09158 Development and regeneration
   04360 Axon guidance
    101439506 (ROCK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101439506 (ROCK1)
   05206 MicroRNAs in cancer
    101439506 (ROCK1)
   05205 Proteoglycans in cancer
    101439506 (ROCK1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    101439506 (ROCK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101439506 (ROCK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dnm01001]
    101439506 (ROCK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:dnm03036]
    101439506 (ROCK1)
Enzymes [BR:dnm01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     101439506 (ROCK1)
Protein kinases [BR:dnm01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   101439506 (ROCK1)
Chromosome and associated proteins [BR:dnm03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    101439506 (ROCK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Pkinase_C DUF1192 KASH_CCD APH
Other DBs
NCBI-GeneID: 101439506
NCBI-ProteinID: XP_004484274
Ensembl: ENSDNOG00000014777
LinkDB
Position
Unknown
AA seq 1296 aa
MDKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKATRKVYAMKLLSKFEMIKRSD
SAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARF
YTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGT
PDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSL
TFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVP
DLSSDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTS
ANVDKSLESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRSLE
STVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEISTLKDQLEDLKKVSQNSQLANE
KLAQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVNQLESLNRELQERNRILENSKSQ
TDKDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEEERKEAQDM
LNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKITKAHLTDKHQSIEEAKSVAMCEMKK
KLKEEREAREKAENRIVQTEKQCSMLDVDLKQSQQKIEHLTENKERMEDEVKNLTLQLEQ
ESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEVEEKNRENLKKIQELQNEKETLATQLDLAETK
AESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSMLTKDNELLRKE
NEELTENMKKAEEEYKSKKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKID
RKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQM
QLASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGW
KKQYVVVSSKKILFYNDEQDKEQSSPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQI
LYANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPA
LECRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPK
NPPSSFVRASPRTLSTRSTANQSFRKVVKNASGKTS
NT seq 3891 nt   +upstreamnt  +downstreamnt
atggataaagacacaataaataaaattagagacctacgtatgaaagctgaagattatgaa
gtagtgaaggtgattggtagaggtgcatttggagaagttcaattggtaagacataaagcc
accaggaaggtatatgctatgaaattactcagcaaatttgaaatgattaagagatctgat
tctgcttttttctgggaagaacgggacatcatggcttttgctaacagcccctgggttgtt
cagcttttttatgcattccaagatgatcgttatctctacatggtgatggaatatatgcct
ggtggagatcttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattc
tatactgcagaagtagttcttgcattggatgcaatccattccatgggttttattcataga
gatgtgaagcctgataacatgttgctggataaatctggacatttgaagttagcagatttt
ggtacttgtatgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaaca
cctgactatatttcccctgaagtattaaaatcccaaggtggtgatggttattatggacga
gaatgtgactggtggtcagttggtgtatttttatatgaaatgcttgtaggtgatacacct
ttttatgcagattctctggttgggacttacagtaagattatgaaccataaaaattcactt
accttccctgatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttcctt
accgacagagaagtgagattagggcgaaatggtgtagaagaaatcaaacgacatcttttc
ttcaaaaatgatcaatgggcttgggaaacactccgcgacactgtagcaccagtagtacct
gatttgagtagtgacattgatacaagtaactttgatgacttggaagaagacaagggagat
gaagaaacatttccaattcctaaagcttttgttggcaatcaactaccttttgtaggattt
acatattatagcaatcgtagatacctatcttcagcaaatcctaatgataacagaactagt
gccaatgtggataaaagcttggaaagtttgcaaaaaaccatctacaagctggaagaacaa
ctacataatgaaatgcaattaaaagatgaaatggagcagaaatgcagaacttccaatata
aagctagacaagataatgaaagaattggatgaagagggaaatcaaagaagaagtctggaa
tctaccgtgtctcaaattgagaaggagaaaatgttgctacagcacagaataaatgagtac
caaagaaaagcggaacaggaaaatgagaagaggaggaatgtagaaaatgaaatttctaca
ttaaaggatcagttggaagacttaaagaaagtaagtcagaattcacagcttgctaatgag
aagctggcacaattacaaaagcagctggaagaagccaacgacttacttaggacagaatca
gacacagctgtaagattaaggaagagtcacacagagatgagcaagtcagttaatcagctg
gagtctctgaacagagaattgcaggagagaaatagaattttagagaattccaagtcacaa
acagacaaggattattaccaactgcaagctgtattagaagctgaacgaagagatagaggt
catgattctgagatgattggagaccttcaagctcgaattacgtctttacaagaggaggtg
aagcatctcaaacataatcttgaaaaagtagaagaagaaagaaaagaggctcaagacatg
cttaatcattcagaaaaggaaaagaataatttggagatagatttaaattacaagcttaaa
tcattacaacaacgattagaacaagaggtaaatgaacataaaataaccaaagcccattta
actgataaacatcaatctattgaagaagcaaagtctgttgcaatgtgtgagatgaaaaaa
aagctgaaggaagagagagaagctcgagagaaggctgaaaataggattgttcagactgag
aaacaatgttccatgctagatgttgatctgaaacagtctcagcagaagatagagcatttg
actgaaaataaagaaaggatggaggatgaagttaagaatctcacactgcaactggaacag
gaatcaaataagcgactcttgttacaaaatgaattgaagactcaagcgtttgaggcagac
aatttaaagggtttagaaaagcagatgaaacaggaaataaatactttattggaagcaaag
agattattagaatttgagttggctcagcttacaaaacaatatagaggaaatgaaggacag
atgcgggaactacaagatcagcttgaggctgagcaatatttctcaaccctttataaaacc
caggtaaaggaacttaaagaagaagttgaagaaaaaaacagagaaaatttaaagaaaata
caggaactacaaaatgaaaaagaaactcttgctactcagctggaccttgcagaaacgaaa
gctgaatctgagcagttggctcgagggcttttggaagaacagtattttgaattgacccaa
gaaagcaagaaagctgcttcaagaaatagacaggagattacagataaagatcatactgtt
agtcggctagaagaaacaaacagcatgctaaccaaagataatgaattactaaggaaagaa
aatgaagagctaactgaaaacatgaaaaaagcagaggaagaatataaatcgaagaaggaa
gaagagatcagtaatcttaaagctgcctttgaaaagaatatcaatacagaacgaaccctt
aaaacacaggctgttaataagctggcagaaataatgaatcgaaaagactttaaaattgat
agaaagaaagctaatacacaagatttgagaaagaaggaaaaggaaaatcgaaaactacag
ctggaactcaaccaggaaagagagaaattcaaccagatggtagtgaaacatcagaaggaa
ctgaatgacatgcaggcgcaattggtagaagaatgtacacatagaaatgagcttcaaatg
cagttggctagcaaagagagtgatattgagcaattgcgtgctaaacttttggacctttcg
gattctacaagtgttgctagttttcctagtgctgatgaaacggatggaaaccttccagag
tcaagaattgaaggttggctttcaataccaaatagaggaaatatcaaaagatatggctgg
aagaaacagtatgttgtggtaagcagcaaaaaaattttattttataatgatgaacaagat
aaagagcaatccagtccatctatggtattggacatagataaattatttcatgttcgacct
gtaacccaaggtgatgtctatagagctgaaactgaagaaattcctaaaatattccagata
ctatatgcaaatgaaggtgaatgtagaaaagatgtggagatggagccggtacaacaagct
gaaaaaactaattttcaaaatcacaaaggccatgagttcattcctacactataccacttt
ccagccaactgtgaggcctgtgccaaaccactctggcatgtttttaaaccacctcctgcc
ttggaatgtcgaagatgccatgttaagtgccacagagatcacttagataagaaagaggac
ttaatttctccatgtaaagtaagttacgatgtgacatcagcaagagatatgctgctatta
gcatgttctcaggatgaacaaaaaaaatgggtaactcatttagtaaagaagatccccaag
aacccaccatctagttttgttcgtgcatcccctcgcacactttctacaagatcaactgca
aatcagtctttccggaaagtggtcaaaaatgcatctggaaagactagttaa

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