Dokdonia sp. MED134: MED134_04314
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Entry
MED134_04314 CDS
T03275
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase 1
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
dok
Dokdonia sp. MED134
Pathway
dok00260
Glycine, serine and threonine metabolism
dok00261
Monobactam biosynthesis
dok00270
Cysteine and methionine metabolism
dok00300
Lysine biosynthesis
dok01100
Metabolic pathways
dok01110
Biosynthesis of secondary metabolites
dok01120
Microbial metabolism in diverse environments
dok01230
Biosynthesis of amino acids
Module
dok_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
dok_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
dok00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MED134_04314 (thrA)
00270 Cysteine and methionine metabolism
MED134_04314 (thrA)
00300 Lysine biosynthesis
MED134_04314 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
MED134_04314 (thrA)
Enzymes [BR:
dok01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
MED134_04314 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
MED134_04314 (thrA)
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Ortholog
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
ACT_7
NAD_binding_3
ACT
Mating_N
ACT_6
Motif
Other DBs
NCBI-ProteinID:
EAQ39946
LinkDB
All DBs
Position
686023..688458
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AA seq
811 aa
AA seq
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MRVLKFGGTSVGSVENIEKTIAIVANQAAQSPVAVVVSALGGVTDLLLKAGALAAKKEES
YKDIFKEISQKHLSFTETLTGGDQKVLNEITLQMSHLEDLLKGIYLINELSPKTLDKLAA
YGELTSSYIIAAAFEHKSIDASLKDSRELIITDANHTKAGVLYEITNQNITTYFAEKKAK
ITVLGGFIARTEAGDTSTLGRGGSDFTAAIIAAALDVEQLEIWTDVSGMFSANPKLVKQA
KPIQEISYHEAMELSHFGAKVLYPPTIVPVLSKNIPIYIKNTMAPEEPGTRIGNQDIAHP
NPIKGISHISDVALLTLEGAGMVGISGISKRLFEVLSQQQVNIILITQASSEHSICIGVM
EADALRAKTAIETEFAYELSLHKIDPVIVETSLAIIALVGESMKSHQGISGKMFSTLGRN
NVNIRAIAQGASEKNISAVIAEKDVKKALNSLHEVFFEGNRKQINLFVTGVGNVGAKLLE
QINNQKQYLKEHLNLNIRVLGLSNSRKMLVSQDPIDLNNWEAQLDGGEKADILRFRESVI
NLNQRNSVFVDITANEPVAMAYEEYLRNSIAVVACNKIAAAGKQEYYANLKRLSRKYNAP
FKFETNVGAGLPIIDTLQNLIASGDRITKVQAVLSGSLNFVFNNFKSGGSFYDVVQQAKE
EGYTEPDPRIDLSGVDVARKILILARESGLELELEDIVNTPFLTKNNLESTDVPHFFETL
KEDAAHFEKLVADATAAGKRLKYVAQLDNGKASVGLQSVGADSPFYNLEGSDNIVLFYTA
RYPEQPLIVKGAGAGGDVTASGLFSDIIRLR
NT seq
2436 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtattaaaatttggaggcacttctgtaggaagtgtagaaaacatagaaaaaaca
attgccatcgtggcaaaccaggcagctcaaagtcctgtagccgtagtcgtgtctgcccta
ggtggtgtaacagatttgttactaaaggctggagcactagcagcaaaaaaagaagagagc
tataaagatatttttaaagaaatctctcaaaagcatttgtcatttactgaaacgcttact
ggtggtgaccaaaaagttctcaacgagattactttacaaatgtcgcacctagaggactta
ctcaaaggtatctatcttataaatgaactctctccaaaaaccttagataaactagccgct
tatggcgaacttacaagtagctacatcatagccgctgcatttgagcataaaagtatagat
gcaagtcttaaagatagtagagaacttattataacagatgcaaaccacacaaaggccggg
gttctttatgagattacaaaccaaaacatcaccacatattttgctgaaaagaaagcaaaa
atcactgttctaggcggatttatcgcacgtacagaggcaggtgatacaagtacactaggt
cgtggaggatcagactttacagcagcaattatagcagcagccctagatgtagagcaacta
gaaatctggacagatgtaagcggtatgttttcggcaaatccaaagctggtaaaacaggca
aaacccatacaagaaatctcgtaccacgaggctatggagttatcgcattttggggcaaaa
gtactctaccctcctactattgtacccgtattgagtaaaaacatacctatctatattaaa
aacacaatggctccagaagagcccggtacacgtataggtaatcaagacatcgcacacccc
aaccctattaaaggaatatcacatataagtgatgtggctttattaacccttgagggagca
ggtatggtaggtatatctggtatctcaaaacgtctgtttgaagtactatcgcaacagcaa
gttaatatcatactcattactcaagcttccagtgagcacagtatctgtataggtgtgatg
gaggcagatgccttacgtgcaaaaacagcgatagaaacagagtttgcttacgaactatcg
ttgcataaaattgacccggtaattgttgagacgtctctagccattatagcgcttgtaggt
gaatctatgaaaagtcatcaaggcatctcaggaaagatgttttctaccctaggtagaaac
aacgtaaatatacgcgccattgcacaaggagcaagtgagaaaaacatctctgccgtgatt
gccgagaaagatgtaaaaaaagccttaaatagcttgcacgaagtattctttgaaggtaac
cgtaagcaaataaacctatttgtaacaggtgtaggtaacgtaggtgcaaagcttcttgag
caaattaacaatcaaaagcaataccttaaagagcacctcaacctcaacataagagtacta
ggactttctaacagtcgcaagatgcttgtatcgcaagaccctatagatctcaataactgg
gaggcacaactagatggaggagaaaaagcagatattttacgctttcgcgaaagcgtaata
aacctcaaccagcgcaactcagtttttgtagacatcaccgcaaatgaacctgtggcaatg
gcatatgaggaatacttaagaaatagcattgccgtggttgcttgtaacaaaatagccgcc
gcaggtaagcaagagtattatgcaaatctcaaaagacttagccgcaagtacaacgctcca
tttaagtttgagactaatgtgggcgcaggactgcctataatagacaccttgcaaaacctt
attgcctctggtgatagaattactaaggtgcaggccgtactctcgggaagcttaaacttt
gtttttaacaactttaaaagtggtggcagcttttatgatgtggtacaacaagccaaagaa
gaaggatatacagagccagacccacgtatagatttaagcggtgtagatgtggcacgtaaa
attcttatactagctagagaaagcggtcttgagctagagctagaagatattgtaaacaca
cctttcttaaccaaaaacaatctagaaagcacagacgttcctcacttctttgaaacactt
aaagaagacgcagcacactttgaaaaactagttgccgatgctacagcagcaggcaaacgc
cttaagtatgtagcccagctagataatggtaaagcaagcgtaggcttacagtctgtgggt
gcagacagtccgttttacaaccttgaagggtctgataatattgttttattttacacagca
cgttatccagagcaaccgcttattgtaaaaggtgcaggtgcaggaggagatgttactgcc
agcggactcttcagcgatatcataagacttagataa
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