Domibacillus sp. DTU_2020_1001157_1_SI_ALB_TIR_016: RRU94_12030
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Entry
RRU94_12030 CDS
T09442
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
dom
Domibacillus sp. DTU_2020_1001157_1_SI_ALB_TIR_016
Pathway
dom00290
Valine, leucine and isoleucine biosynthesis
dom00620
Pyruvate metabolism
dom01100
Metabolic pathways
dom01110
Biosynthesis of secondary metabolites
dom01210
2-Oxocarboxylic acid metabolism
dom01230
Biosynthesis of amino acids
Module
dom_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
dom00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
RRU94_12030
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
RRU94_12030
Enzymes [BR:
dom01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
RRU94_12030
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
WNS81518
UniProt:
A0AA96SC71
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Position
2:complement(840716..842404)
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AA seq
562 aa
AA seq
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MKNVNKYTRNYFMPPTTSLKWTQKEYITEAPTWCSVDLRDGNQALIIPMNLQEKLEYFQV
LVDVGFKEIEVGFPAASETEYTFLRTLIEQDLIPDDVTIQVLTQSREHIIKKTFESLRGA
KSAVVHLYNSTSLAQREQVFKRSKEEIKEIAVSGAKLLKKYAAEVEGNFKFQYSPESFTG
TEIEYALDVCNSVLDVWQPTADNKVIINLPATVSMSMPHVYASQIEFMSENMKYRENVIL
SLHPHNDRGTGVADAELGVLAGADRVEGTLFGNGERTGNVDIVTLALNMYTHGVDPKLNL
DNLPAIQEVYERVTRMTVPDRQPYAGKLVFTAFSGSHQDAIAKGMKWREQEEREHWTVPY
LPVDPEDIGREYEGEVIRINSQSGKGGIGYLLEQAYGFELPPKMRETLGYKVKNVSDRSQ
KELMTNEIHDIFMEEFVNVSEPAKLIDYTFEGKDAVNITIEVNINSQSSEWHGSGNGRLD
AVNNAIQKELGISYKDLTYKEHAQEIGSQANAVSYVSITSDNGAVYWGCGIDPDIMNSSI
KALFSAVNNLLKVEQERFAATK
NT seq
1689 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaatgtaaacaaatacacgcgcaattactttatgccgccgacaacaagcttaaaa
tggacacaaaaagagtacatcaccgaagctccaacatggtgcagtgttgatttgcgtgat
ggaaaccaggcgctgatcatcccgatgaacctgcaggaaaaactggaatatttccaagtg
cttgtagatgttggttttaaagaaatcgaggttggtttcccggccgcatccgaaaccgaa
tatacatttcttcgcacattaattgaacaagatttgattccagatgatgtgacaattcaa
gtgttgacgcagtcacgtgagcatattatcaaaaaaacatttgaatcgcttcgcggtgca
aaaagcgcggtcgttcacttgtacaactctacttcccttgcacagcgtgagcaggtgttt
aagcgttctaaagaagaaattaaagaaattgcagtcagcggcgcaaagctgttgaaaaaa
tatgcagctgaagtagaaggcaactttaagttccagtactcgccggaaagctttacaggt
acggaaattgagtacgcgcttgatgtatgcaacagcgtccttgacgtgtggcagccaacc
gctgacaacaaagtgattatcaaccttccggctactgtttctatgtctatgccgcacgtg
tacgcgagccagattgaattcatgagcgaaaacatgaagtaccgtgaaaatgtgatttta
tctcttcatccacacaatgaccgcggcacaggcgttgcagatgcagagcttggcgtactc
gcaggcgcggaccgcgtagagggcacgctgtttggcaacggtgaacgaactggaaatgta
gatatcgtcacgttggcgcttaatatgtatacacatggtgtagatccgaaattaaatttg
gataaccttccggcgatccaggaagtgtatgaacgtgttacccgcatgacggttccagac
cgccagccgtatgcaggcaagcttgttttcaccgctttctcaggttcacaccaggatgcg
attgcgaaaggcatgaaatggcgtgaacaggaagaacgcgagcattggaccgttccatat
ttgccagttgatccagaagatatcggccgcgagtatgaaggagaagttatccgcattaac
agccagtcaggcaaaggcggtatcggctatcttcttgaacaggcatacggctttgaactt
ccgccaaaaatgcgtgaaacacttggctataaagtgaaaaacgtgtctgaccgcagccaa
aaagaattgatgacaaacgaaattcacgacatctttatggaggaatttgtgaatgtaagc
gagccggctaagctaatcgattatacatttgaaggaaaagatgcagtgaatattacaatt
gaagtaaacataaatagccagtcaagtgaatggcacggcagcggaaacggccgcctggac
gccgtgaataatgcgatccaaaaagagcttggcatttcctataaagatttaacgtacaaa
gagcatgcccaggaaatcggttcacaggccaatgccgtttcttacgtgagcatcacatct
gacaatggtgctgtttactggggctgcggcatcgacccggatatcatgaactcatctatt
aaagccctgttcagtgctgtaaacaatttgttgaaagtagaacaggaacgctttgcagca
acaaaataa
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