Dipodomys ordii (Ord's kangaroo rat): 105982453
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Entry
105982453 CDS
T07834
Symbol
Igf1r
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord01521
EGFR tyrosine kinase inhibitor resistance
dord01522
Endocrine resistance
dord04010
MAPK signaling pathway
dord04014
Ras signaling pathway
dord04015
Rap1 signaling pathway
dord04066
HIF-1 signaling pathway
dord04068
FoxO signaling pathway
dord04081
Hormone signaling
dord04114
Oocyte meiosis
dord04140
Autophagy - animal
dord04144
Endocytosis
dord04150
mTOR signaling pathway
dord04151
PI3K-Akt signaling pathway
dord04152
AMPK signaling pathway
dord04211
Longevity regulating pathway
dord04213
Longevity regulating pathway - multiple species
dord04510
Focal adhesion
dord04518
Integrin signaling
dord04520
Adherens junction
dord04550
Signaling pathways regulating pluripotency of stem cells
dord04730
Long-term depression
dord04913
Ovarian steroidogenesis
dord04914
Progesterone-mediated oocyte maturation
dord05200
Pathways in cancer
dord05202
Transcriptional misregulation in cancer
dord05205
Proteoglycans in cancer
dord05214
Glioma
dord05215
Prostate cancer
dord05218
Melanoma
dord05224
Breast cancer
dord05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105982453 (Igf1r)
04014 Ras signaling pathway
105982453 (Igf1r)
04015 Rap1 signaling pathway
105982453 (Igf1r)
04066 HIF-1 signaling pathway
105982453 (Igf1r)
04068 FoxO signaling pathway
105982453 (Igf1r)
04151 PI3K-Akt signaling pathway
105982453 (Igf1r)
04152 AMPK signaling pathway
105982453 (Igf1r)
04150 mTOR signaling pathway
105982453 (Igf1r)
09133 Signaling molecules and interaction
04081 Hormone signaling
105982453 (Igf1r)
04518 Integrin signaling
105982453 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
105982453 (Igf1r)
04140 Autophagy - animal
105982453 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
105982453 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105982453 (Igf1r)
04520 Adherens junction
105982453 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
105982453 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
105982453 (Igf1r)
04914 Progesterone-mediated oocyte maturation
105982453 (Igf1r)
09156 Nervous system
04730 Long-term depression
105982453 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
105982453 (Igf1r)
04213 Longevity regulating pathway - multiple species
105982453 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105982453 (Igf1r)
05202 Transcriptional misregulation in cancer
105982453 (Igf1r)
05205 Proteoglycans in cancer
105982453 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
105982453 (Igf1r)
05214 Glioma
105982453 (Igf1r)
05218 Melanoma
105982453 (Igf1r)
05215 Prostate cancer
105982453 (Igf1r)
05224 Breast cancer
105982453 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105982453 (Igf1r)
01522 Endocrine resistance
105982453 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dord01001
]
105982453 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
dord04090
]
105982453 (Igf1r)
Enzymes [BR:
dord01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
105982453 (Igf1r)
Protein kinases [BR:
dord01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
105982453 (Igf1r)
CD molecules [BR:
dord04090
]
Proteins
105982453 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
FN3_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
105982453
NCBI-ProteinID:
XP_012867500
UniProt:
A0A1S3EU99
LinkDB
All DBs
Position
Unknown
AA seq
1369 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLCLSAALSLWPTSGEICGPGIDIRNDYQQLRRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKSPKECGD
LCPGTMEEKPVCEKTTINNEYNYRCWTTNHCQKMCPSACGKRACTEDNECCHAECLGSCT
VPDNATACVACRHYFHRGECVPDCPPDTYKFEGWRCVDRDACANIPSAESGDSEGFVIHD
GACMQECPSGFIRNGSQSMYCIPCEGPCPKVCGEEEKKTKTIDSVTSAQMLQGCTIFRGN
LLINIRRGNNIASELETFMGLIEVVTGYVKIRHSHALVSLSFLKNLRHILGEEQLEGNYS
FYVLDNQNLQQLWDWDHRNLTIKSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINT
RNNGERASCESDVLHFTSTTTWKNHIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYD
GQDACGSNSWNMVDVDLPNNKDKEPGILLQGLKPWTQYAVYVKAVTLTMVENDHIRGAKS
EILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYR
HNYCSKDKIPIRKYADGTIDVEEVTENPNTEVCGGEKGPCCTCPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERKRRDIMQVANTTMSSRSRNATVVDVYNITDPEEVETEYPFFE
SRVDNKERTVISNLQPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGARLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAIVLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYIPDEWEVAREKITMNRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPETEQKNVVLEPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIIGSIKDEMEPGFREVSFYYSEENKPPESEELDLEPENMESVPLDPSASSSSLPLPD
RHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERPLPLPQSSTC
NT seq
4110 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtgtctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtggaccaggcatcgacatccgc
aatgactaccagcagctgaggcgcctggagaactgcacagtgatcgagggctacctccac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcaccgtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcctcggggacctcttc
cccaacctcacggtcatccgtggctggaaactcttctacaactacgccctggtcatcttc
gagatgaccaatctcaaggacattgggctgtacaacctgaggaacattactcggggggct
atcagaatcgagaagaatgctgacctctgttacctctccacggtggactggtccctgatc
ctggatgccgtgtccaataactacatcgtggggaacaagtccccaaaggaatgtggggac
ctgtgtcccgggaccatggaggagaagccggtgtgtgagaagaccaccatcaacaacgag
tacaactaccgctgctggaccacgaatcactgccagaaaatgtgccccagcgcgtgcggg
aagcgcgcgtgcacggaggacaacgagtgctgccacgccgagtgcctgggcagctgcacg
gtgcccgacaacgccacggcgtgcgtggcctgccgccactacttccaccgcggcgagtgc
gtgcccgactgcccgcccgacacctacaagttcgagggctggcgctgtgtggaccgcgac
gcctgcgccaacatccccagcgccgagagcggcgactcggagggcttcgtcatccacgac
ggcgcctgcatgcaggagtgcccgtcgggcttcatccgcaacggctcccagagcatgtac
tgtatcccctgcgaaggtccttgccccaaggtttgtggagaggaagaaaagaagacaaaa
actatcgactccgttacttctgctcagatgctccaaggatgcaccatcttccggggaaat
ttgctcattaatatccgacgaggcaataacattgcttcggagctggagaccttcatgggg
ctcattgaggtggtgacgggttacgtgaagatccgccattcgcacgccctggtctccttg
tccttcctcaaaaaccttcgccatattctaggagaggagcagctggaagggaactactcc
ttctacgtcttggataaccagaaccttcagcagctgtgggactgggaccaccgcaacctc
accatcaaatcggggaagatgtactttgcattcaaccccaagctgtgtgtttccgaaatt
taccgcatggaggaagtgacggggacgaaaggacgccagagcaaaggggacataaacact
aggaacaatggggaaagagcctcctgtgaaagtgacgtcctgcattttacctctaccacc
acgtggaagaaccacatcatcatcacgtggcaccggtaccggcccccggactacagggac
ctcatcagcttcaccgtgtactacaaggaggcaccctttaaaaacgtcacagaatatgat
ggacaggatgcctgtggctccaacagctggaacatggtagacgtggacctccctaacaat
aaagacaaggagcccggcattctcctgcaggggctgaagccctggacacaatatgccgtc
tacgtcaaggccgtgaccctcaccatggtagagaatgaccacatccgtggggccaagagt
gaaatcttatacattcgcaccaatgcttcagttccttccattccactggatgtcctctcg
gcttcgaactcctcctctcagctgatcgtgaagtggaatccaccatccctgcccaatggc
aacctgagttactacatcgtgaggtggcagcgacagcctcaggacggctatctgtaccgg
cacaactactgctccaaagacaaaatccccattaggaaatatgccgatggcaccatcgac
gtggaggaggtgacagagaatcccaacacagaggtgtgtggcggggagaaaggaccctgc
tgcacttgccccaaaacggaagctgagaagcaagctgagaaggaggaggccgagtaccgc
aaagtctttgagaatttcctgcacaactcaatctttgtgcccagacctgaaaggaagcgg
agagacatcatgcaggtggccaacaccaccatgtccagccggagcaggaatgccacagtg
gtggacgtctacaatatcacagacccagaagaggtggagacagaataccctttctttgag
agcagagtggataacaaagagagaactgtcatttcgaacctccagcctttcactttgtac
cgcatcgatattcacagctgtaaccacgaggctgagaagttaggttgcagcgcctccaac
tttgtctttgcaagaaccatgcctgcagaaggagcagatgacattcctggaccggtcacc
tgggaaccaaggccagagaactccatctttttaaagtggccagaacctgagaacccaaat
ggactcattctgatgtatgagatcaaatacggttcccaggtggaggaccagcgggaatgt
gtgtccagacaggaatacaggaagtacggaggggccaggcttaaccggctaaacccaggg
aactacaccgcccgaattcaggctacctctctctctggaaatgggtcgtggacagatcct
gtgttcttctatgtcccagccaaaaccacctatgaaaatttcatgcacctgatcatcgct
ctgcccgtggccatcgtcctgatcgtggggggtctggtgatcatgctgtacgtcttccac
agaaagaggaataacagtaggctgggcaacggagtgctctatgcctctgtgaacccagag
tacttcagtgcagcagatgtgtacattcctgatgagtgggaggtagcccgggagaagatc
accatgaaccgggagcttgggcaggggtcctttgggatggtctatgaaggtgtggctaag
ggtgtggttaaagatgagcctgaaaccagagtggccattaagacggtgaacgaggcagcc
agcatgcgggaaaggattgagtttctcaatgaggcttcagtgatgaaggagttcaattgt
caccacgtggtacggttgctgggcgtggtgtcccaaggccagccaacgctggtcatcatg
gaactgatgacccggggcgatctcaaaagttacctcaggtctctgaggccggaaacagag
cagaagaacgtagtcctggaacctcccagtctgagcaagatgatccagatggctggcgag
attgccgacggcatggcatacctcaacgccaacaagtttgtccacagagacctcgcggcc
cgcaattgcatggtggccgaggatttcacagtcaaaatcggagattttggtatgactcga
gatatctatgagacagactactaccggaaaggaggcaagggcctgctgcccgtgcgctgg
atgtccccggagtcacttaaggacggcgtcttcaccacccattcggatgtctggtccttc
ggggtggtcctctgggagatcgccacactggctgagcagccataccaaggcttgtccaac
gagcaagtccttcgcttcgtcatggaaggcgggcttctagacaaaccagacaactgcccc
gacatgctgttcgagctgatgcggatgtgctggcagtacaaccccaagatgcggccctcc
ttcctggagatcatcggcagcatcaaggatgagatggagccgggcttccgcgaggtctcc
ttctactacagcgaggagaacaagccccccgaatccgaggagctggacctggagcccgag
aacatggagagcgtgcccctggacccctcggcctcctcctcctccctgcctctgcccgac
agacactcaggacacaaggccgagaatggcccgggccctggagtgctggtcctgcgagcc
agcttcgacgagagacagccgtacgcgcacatgaacggcggccgcgccaacgagcgcccg
ctgccgctgccccagtcgtccacctgctga
DBGET
integrated database retrieval system
