Dipodomys ordii (Ord's kangaroo rat): 105982575 Help Entry 105982575         CDS       T07834                                  Symbol Sos2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism dord  Dipodomys ordii (Ord's kangaroo rat) Pathway dord01521   EGFR tyrosine kinase inhibitor resistance dord01522   Endocrine resistance dord04010   MAPK signaling pathway dord04012   ErbB signaling pathway dord04014   Ras signaling pathway dord04062   Chemokine signaling pathway dord04068   FoxO signaling pathway dord04072   Phospholipase D signaling pathway dord04150   mTOR signaling pathway dord04151   PI3K-Akt signaling pathway dord04510   Focal adhesion dord04540   Gap junction dord04630   JAK-STAT signaling pathway dord04650   Natural killer cell mediated cytotoxicity dord04660   T cell receptor signaling pathway dord04662   B cell receptor signaling pathway dord04664   Fc epsilon RI signaling pathway dord04714   Thermogenesis dord04722   Neurotrophin signaling pathway dord04810   Regulation of actin cytoskeleton dord04910   Insulin signaling pathway dord04912   GnRH signaling pathway dord04915   Estrogen signaling pathway dord04917   Prolactin signaling pathway dord04926   Relaxin signaling pathway dord04935   Growth hormone synthesis, secretion and action dord05034   Alcoholism dord05160   Hepatitis C dord05161   Hepatitis B dord05163   Human cytomegalovirus infection dord05165   Human papillomavirus infection dord05200   Pathways in cancer dord05205   Proteoglycans in cancer dord05206   MicroRNAs in cancer dord05207   Chemical carcinogenesis - receptor activation dord05208   Chemical carcinogenesis - reactive oxygen species dord05210   Colorectal cancer dord05211   Renal cell carcinoma dord05213   Endometrial cancer dord05214   Glioma dord05215   Prostate cancer dord05220   Chronic myeloid leukemia dord05221   Acute myeloid leukemia dord05223   Non-small cell lung cancer dord05224   Breast cancer dord05225   Hepatocellular carcinoma dord05226   Gastric cancer dord05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:dord00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105982575 (Sos2)    04012 ErbB signaling pathway     105982575 (Sos2)    04014 Ras signaling pathway     105982575 (Sos2)    04630 JAK-STAT signaling pathway     105982575 (Sos2)    04068 FoxO signaling pathway     105982575 (Sos2)    04072 Phospholipase D signaling pathway     105982575 (Sos2)    04151 PI3K-Akt signaling pathway     105982575 (Sos2)    04150 mTOR signaling pathway     105982575 (Sos2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     105982575 (Sos2)    04540 Gap junction     105982575 (Sos2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     105982575 (Sos2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     105982575 (Sos2)    04660 T cell receptor signaling pathway     105982575 (Sos2)    04662 B cell receptor signaling pathway     105982575 (Sos2)    04664 Fc epsilon RI signaling pathway     105982575 (Sos2)    04062 Chemokine signaling pathway     105982575 (Sos2)   09152 Endocrine system    04910 Insulin signaling pathway     105982575 (Sos2)    04912 GnRH signaling pathway     105982575 (Sos2)    04915 Estrogen signaling pathway     105982575 (Sos2)    04917 Prolactin signaling pathway     105982575 (Sos2)    04926 Relaxin signaling pathway     105982575 (Sos2)    04935 Growth hormone synthesis, secretion and action     105982575 (Sos2)   09156 Nervous system    04722 Neurotrophin signaling pathway     105982575 (Sos2)   09159 Environmental adaptation    04714 Thermogenesis     105982575 (Sos2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105982575 (Sos2)    05206 MicroRNAs in cancer     105982575 (Sos2)    05205 Proteoglycans in cancer     105982575 (Sos2)    05207 Chemical carcinogenesis - receptor activation     105982575 (Sos2)    05208 Chemical carcinogenesis - reactive oxygen species     105982575 (Sos2)    05231 Choline metabolism in cancer     105982575 (Sos2)   09162 Cancer: specific types    05210 Colorectal cancer     105982575 (Sos2)    05225 Hepatocellular carcinoma     105982575 (Sos2)    05226 Gastric cancer     105982575 (Sos2)    05214 Glioma     105982575 (Sos2)    05221 Acute myeloid leukemia     105982575 (Sos2)    05220 Chronic myeloid leukemia     105982575 (Sos2)    05211 Renal cell carcinoma     105982575 (Sos2)    05215 Prostate cancer     105982575 (Sos2)    05213 Endometrial cancer     105982575 (Sos2)    05224 Breast cancer     105982575 (Sos2)    05223 Non-small cell lung cancer     105982575 (Sos2)   09172 Infectious disease: viral    05161 Hepatitis B     105982575 (Sos2)    05160 Hepatitis C     105982575 (Sos2)    05163 Human cytomegalovirus infection     105982575 (Sos2)    05165 Human papillomavirus infection     105982575 (Sos2)   09165 Substance dependence    05034 Alcoholism     105982575 (Sos2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105982575 (Sos2)    01522 Endocrine resistance     105982575 (Sos2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH RHG20_PH Motif Other DBs NCBI-GeneID:  105982575 NCBI-ProteinID:  XP_012867680 Ensembl:  ENSDORG00000002613 UniProt:  A0A1S3EUS9 LinkDB All DBs Position Unknown AA seq 1425 aa AA seqDB search MDVFHMWEMSVTHDTPSPVVEVNLEPPYFLQKVSYLHSIRDAIRSAPFLDSVRFRSWNYF KEHKNRAARTTQPFKPGCIALLRRSRSWGRFVLIYKEVLLLSRLFVELDEGDDPFSSIPG VKVQEQVHPNLSANEESLYYIEELIFQLLNKLCMAQPRTVQDVEERVQKTFPHPIDKWAI ADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGYKVDYHVSLYIVAVLEYISADILKLAGN YVFNIRHYEISQQDIKVSMCADKVLMDMFDQDDIGLVSLCEDEPSSSGELNYYDLVRTEI AEERQYLRELNMIIKVFREAFLSDRNLFKPSDIERIFSNISDIHELTVKLLGLIEDTVEM TDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILSPEFNEHFSKLMAKPAVALHFQSIAD GFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKACSEEEEDRECLNQAITALMNLQGSMDR IYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGP LTRVGAKHERHIFLFDGLMISCKPNHCQTRLPGYSSAEYRLKEKFVMRKTQICDKEDTCE CKHAFELVSKDENSIIFAAKSAEEKNNWMAALISLHYRSTLDRMLDSVLLKEENEQPLRL PSPEVYHFVVKDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLT TYRSFCKPQELLNLLIERFEIPEPEPTEADKLAIEKGEQPISADLKRFRKEYVQPVQLRV LNVFRHWVEHHFYDFERDLELLERLESFIKSVRGKAMKKWVESIAKIINRKKQAQANGIS HNITFESPPPPIEWHISRPGQFESFELMTLHPIEIARQLTLLESDLYRKVQPSELVGSVW TKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAILSRIIEILQVFQDLNNFN GVLEIVSAVNSVSVYRLDHTFEALQERKRRILDEAVELSQDHFKKYLVKLKSINPPCVPF FGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPEMRR FFENLNPMGSLSEKEFTDYLFNKSLEIEPRSCKQPPRFPRKSTFSLKSPGIRPNTGRHGS TSGTLRGHPTPLEREPYKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVD LNSSCGSNSIFAPVLLPHSKSFFSSCGSLNKLSEEPLIPPPLPPRKKFDHDASNSKGTMK PDDDPPAIPPRQPPPPKIKPRVPVPTGAFDGQLHSPPPPPPRDPLPDTPPPVPLRPPEHF INCPFNLQPPPLGHLHRDSEWFRDVSTCPNSPSTPPSTPSPRVPRRCYVLSSSNNNLVHP PAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLYRLPFLENAETPQ NT seq 4278 nt NT seq  +upstreamnt  +downstreamnt atggatgtgtttcacatgtgggaaatgtcagtgactcacgatacaccttctccggttgtg gaggtaaatctggagcctccctacttcctgcagaaggtatcttacctgcatagtataaga gatgccataagatccgctccgtttcttgattctgtgcgatttagaagttggaattacttt aaggaacacaaaaatagagcagctcgcacaactcagcctttcaagcctgggtgcattgct ctcttgcgtcgctctcggtcatggggtcggttcgtcctcatttacaaggaggtattgctt ctctcacgtctttttgtagaacttgatgaaggcgatgatccttttagtagtataccaggt gtcaaagttcaggaacaagtacatcccaatctctcagctaatgaagaatctctctactat attgaagagctgatttttcagctgcttaataaattatgcatggcccaaccaaggactgtc caagatgtggaggaacgagtccaaaagacctttcctcatccaattgataagtgggctatt gctgatgcacaatctgccatagagaaaagaaaacgaagaaatcctcttttactgcctgta gacaaaatccatccttcattgaaggaagttctggggtataaagtagactatcatgtgtcc ctatatattgtggctgtactagagtatatctcagcagacattttgaagttggctggtaat tatgtttttaatattcgacattatgaaatatctcaacaggacattaaagtgtcaatgtgt gcagataaggtcttgatggacatgtttgatcaggatgacataggtttggtttctctctgt gaagatgaacctagttcttcaggtgaattaaactactatgaccttgtgaggactgaaatt gcagaagaaagacagtatctacgagagttaaatatgatcataaaagtatttcgagaggcc tttctttctgacagaaatttgtttaagccttctgacattgaaaggattttcagtaacatt tcagatatacatgaattgactgtgaaacttttaggcttgattgaagacactgttgaaatg actgatgaaagtagtcctcatcccttagctggcagctgttttgaagatttagcagaggaa caagcatttgatccatatgagacattatcacaggacattctttcacctgagtttaatgag cacttcagtaagttgatggctaagcctgcagttgctttacactttcagtctattgctgat ggctttaaggaggcagttcgttatgttcttccacgacttatgttggtgccagtatatcat tgttggcattattttgaattgctcaagcaattgaaagcatgtagtgaagaggaagaagac agagaatgtttgaatcaagctattacagctcttatgaatctccagggtagtatggaccga atttacaagcaatattcacctagacgtcgacctggggatcctgtttgccctttttataat cgtcaattaagaagcaagcatctagctatcaaaaaaatgaatgaaattcagaaaaacata gatggatgggaaggcaaagatattggacagtgttgtaatgaatttataatggaaggacca ttgactagagttggtgcaaaacatgaacggcacattttcctctttgatggcttaatgatc agctgtaaacctaatcattgccaaacccggcttccaggttacagtagtgcagaatacaga ttaaaagaaaagtttgtcatgagaaaaacacaaatctgtgataaagaagatacttgtgaa tgcaaacatgcttttgaattagtatccaaagatgaaaacagcataatatttgctgctaag tctgctgaagagaaaaataattggatggcagcccttatttctcttcattatcgtagtact ctagatcgaatgcttgattcagtattactgaaagaagaaaatgagcaaccactaagatta ccaagcccagaagtatatcattttgtggtaaaagactcagaggaaaacattgtttttgaa gacaacttgcaaagtagaagtggaatccccattattaaaggaggaactgtggtgaaatta attgaaaggttaacatatcatatgtatgccgatcccaattttgttcggacttttcttact acgtatcgttcattttgtaaaccacaggagttgctaaatttgctgattgaacgatttgag attccagagccagaacctactgaagcagacaaattggcaatagagaaaggggagcagcca atcagtgcagaccttaaaagatttcgcaaggaatatgttcaaccagtacaacttagggtc ttaaatgtgtttcggcactgggttgaacaccatttttatgactttgaaagagatttggaa ttgcttgaaagactagaatctttcattaaaagtgtaagaggaaaagctatgaagaaatgg gtagagtcaattgctaagatcatcaatagaaagaaacaagctcaggcaaatggaataagc cataatattacctttgaaagtccacctccaccaattgaatggcatatcagtagaccagga caatttgagtcatttgagctcatgacgcttcatccaatagaaattgcacgtcaactaaca cttttagaatctgatctctacaggaaagttcaaccttctgaacttgttgggagtgtgtgg accaaagaagataaagaaataaattccccaaatttattaaaaatgattcgccatacaaca aatctcacactgtggtttgaaaaatgcattgtggaagcagaaaattttgaagaacgggtg gcaatactaagtagaattatagaaattctgcaagtttttcaagatttgaacaatttcaat ggtgtattggagatagtcagtgcggtaaattcagtgtcagtatacagattagaccataca tttgaggcattgcaggaaagaaagcggagaattttggatgaagctgtggaattaagccag gatcactttaaaaaatacctagtaaagcttaaatcaatcaatccaccttgcgtgcctttt tttggaatatatttaacaaatattctgaagacggaagagggaaataatgattttctaaaa aagaaagggaaagatttaatcaatttcagtaagagaaggaaagtagctgaaattactgga gaaattcagcaatatcagaatcagccttactgtttacggatagaaccagaaatgaggaga ttctttgaaaaccttaaccccatgggaagtttatctgaaaaagaatttacagactatttg ttcaataagtcactagaaattgagccccgaagttgcaaacagccacctcgatttcctagg aaatcaaccttctccttaaaatctcctggaataagacctaatacaggtcgtcatggctct acctcaggcactttacgaggtcatccaacaccgttagaaagagaaccatataagataagc tttagtcggattgctgaaactgagcttgaatcaacagtatcagcaccaacatctccaaat acaccatctactccaccagtatctgcttcttcagacttgagtgtgtttttagatgtggat ctcaatagttcctgtggcagcaatagcatctttgctccagtgctcttgccacactcaaag tctttcttcagttcatgtgggagtttaaataaactaagtgaagagccactgattcctcct cctctgcctcctcgaaaaaagtttgatcatgatgcttcaaattccaagggaactatgaaa cctgatgatgaccctcctgctattccaccaagacaacctccccctccaaagataaaaccc agagttcctgttcctactggtgcatttgatgggcagctgcacagtccacctccaccaccg ccaagagatcctcttcctgacactcctccaccagttccccttcggcctccggaacacttt ataaactgtccatttaatcttcagccacctccactgggacatcttcacagagattcagag tggttcagagacgttagtacctgtccaaattcaccaagcactcctcctagcacaccctct ccaagagtaccacgtcgatgctatgtgctcagttctagtaacaacaatcttgttcatcct ccagctccccctgttccaccaaggcagaattcaagtcctcacctaccaaaactgccacca aagacttacaagcgggagctttcgcatcccccattgtacagactgccttttctagaaaat gcagaaactcctcaatga

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