Dipodomys ordii (Ord's kangaroo rat): 105982979
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Entry
105982979 CDS
T07834
Symbol
Plcg2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord00562
Inositol phosphate metabolism
dord01100
Metabolic pathways
dord01521
EGFR tyrosine kinase inhibitor resistance
dord04012
ErbB signaling pathway
dord04014
Ras signaling pathway
dord04020
Calcium signaling pathway
dord04062
Chemokine signaling pathway
dord04064
NF-kappa B signaling pathway
dord04066
HIF-1 signaling pathway
dord04070
Phosphatidylinositol signaling system
dord04072
Phospholipase D signaling pathway
dord04360
Axon guidance
dord04370
VEGF signaling pathway
dord04380
Osteoclast differentiation
dord04611
Platelet activation
dord04613
Neutrophil extracellular trap formation
dord04625
C-type lectin receptor signaling pathway
dord04650
Natural killer cell mediated cytotoxicity
dord04662
B cell receptor signaling pathway
dord04664
Fc epsilon RI signaling pathway
dord04666
Fc gamma R-mediated phagocytosis
dord04670
Leukocyte transendothelial migration
dord04722
Neurotrophin signaling pathway
dord04750
Inflammatory mediator regulation of TRP channels
dord04919
Thyroid hormone signaling pathway
dord04933
AGE-RAGE signaling pathway in diabetic complications
dord04935
Growth hormone synthesis, secretion and action
dord05167
Kaposi sarcoma-associated herpesvirus infection
dord05169
Epstein-Barr virus infection
dord05170
Human immunodeficiency virus 1 infection
dord05171
Coronavirus disease - COVID-19
dord05200
Pathways in cancer
dord05205
Proteoglycans in cancer
dord05206
MicroRNAs in cancer
dord05214
Glioma
dord05223
Non-small cell lung cancer
dord05225
Hepatocellular carcinoma
Module
dord_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
105982979 (Plcg2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
105982979 (Plcg2)
04014 Ras signaling pathway
105982979 (Plcg2)
04370 VEGF signaling pathway
105982979 (Plcg2)
04064 NF-kappa B signaling pathway
105982979 (Plcg2)
04066 HIF-1 signaling pathway
105982979 (Plcg2)
04020 Calcium signaling pathway
105982979 (Plcg2)
04070 Phosphatidylinositol signaling system
105982979 (Plcg2)
04072 Phospholipase D signaling pathway
105982979 (Plcg2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
105982979 (Plcg2)
04613 Neutrophil extracellular trap formation
105982979 (Plcg2)
04625 C-type lectin receptor signaling pathway
105982979 (Plcg2)
04650 Natural killer cell mediated cytotoxicity
105982979 (Plcg2)
04662 B cell receptor signaling pathway
105982979 (Plcg2)
04664 Fc epsilon RI signaling pathway
105982979 (Plcg2)
04666 Fc gamma R-mediated phagocytosis
105982979 (Plcg2)
04670 Leukocyte transendothelial migration
105982979 (Plcg2)
04062 Chemokine signaling pathway
105982979 (Plcg2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
105982979 (Plcg2)
04919 Thyroid hormone signaling pathway
105982979 (Plcg2)
09156 Nervous system
04722 Neurotrophin signaling pathway
105982979 (Plcg2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
105982979 (Plcg2)
09158 Development and regeneration
04360 Axon guidance
105982979 (Plcg2)
04380 Osteoclast differentiation
105982979 (Plcg2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105982979 (Plcg2)
05206 MicroRNAs in cancer
105982979 (Plcg2)
05205 Proteoglycans in cancer
105982979 (Plcg2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
105982979 (Plcg2)
05214 Glioma
105982979 (Plcg2)
05223 Non-small cell lung cancer
105982979 (Plcg2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
105982979 (Plcg2)
05171 Coronavirus disease - COVID-19
105982979 (Plcg2)
05167 Kaposi sarcoma-associated herpesvirus infection
105982979 (Plcg2)
05169 Epstein-Barr virus infection
105982979 (Plcg2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
105982979 (Plcg2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105982979 (Plcg2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dord04131
]
105982979 (Plcg2)
Enzymes [BR:
dord01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
105982979 (Plcg2)
Membrane trafficking [BR:
dord04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
105982979 (Plcg2)
Endocytosis
Macropinocytosis
Phospholipase C
105982979 (Plcg2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SH2
PI-PLC-Y
EF-hand_PLCG2
PI-PLC-X
C2
PH
PH_12
EF-hand_PLCG1
SH2_1
PH_14
Motif
Other DBs
NCBI-GeneID:
105982979
NCBI-ProteinID:
XP_012868155
UniProt:
A0A1S3EW59
LinkDB
All DBs
Position
Unknown
AA seq
1111 aa
AA seq
DB search
MTTVGNVDALPEHEKSQLKRALELGTVMTVFSFRKCTPERRTVQVIMETRQVAWSKTADK
MEGFLDIMEIKEIRPGKNSKDFERAKAVRHKEDCCFTILYGTQFVLSTLSLATDSREEAA
KWLSGLKILHQEALSASTPSMIESWLRKQIYSVDQTRRNSIGLREMKAILPTVNFKVNSV
KLLKDKFMEISTHKDELSFEQLHLFYKKLMFEQQKSILDEFKKDSSVFILGSTDRLEASV
VYLQDFQRFLLHEQQEPWAQDINKVRERMTRFIDDTMRETVEPFLFVDEKWTRHYCAIAD
AKLSFSDDIEQNVEEEPPQDTPPTELHLGEKWFHKKVEKRTSAEKLMQQYCLETGAKDGT
FLVRESETYPDNYTLSFWRSGRVQHCLIRSTVEGGAKKYYLTDNLTFPSIYALVQHYREA
HLRCAEFELRLTDAVPNPNPHESKPWYYGQLSRGEAEDMLMRVPRDGAFLIRRREGTDSY
AITFRARGKVKHCRISRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELL
ERYSVVGTARPGPRGLCGSPIPPGGRGSRLLQFLTYLFSRENSIWDDKYDAVDMQDMNNP
LSHYWISSSHNTYLTGDQLRSESSTEAYVRCLRLGCRCIECECRPCSSGGPSPRLRDVPG
PGPLREETGGALGAPGLECHVSSQIMEDNPLGSLCRGILDLNNYNVVKAPHGKNQKPFVF
ILEPKKQGDPPVEFAADSVEELFEWFQSIRQITWKIDTKENNMKYWEKNQSIAIELSDLV
VYCKPTSKTKDNLENPDFREIRSFVETKADSMVRQKPRELLRYNQKGLTRVYPKGQRVDS
SNYDPFRLWLCGAQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRGEKYDPLPPE
SQRRVVMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWA
PTQEKVTFEIYDPSLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSED
IELASLLVFCEMRPVLECEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKE
FNVNENQLQLYQDRCNRRLREKRVSNSKFYS
NT seq
3336 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccgtgggcaacgtggacgcccttcccgagcatgagaagagtcagctcaagagg
gctctggagctgggcactgtcatgaccgtgtttagtttccgcaagtgcacccccgagcgc
aggaccgtgcaggtgatcatggagacgcggcaagtggcgtggagtaagacggcggacaag
atggaaggcttcttggacatcatggagataaaggagatccgcccggggaagaactccaag
gattttgagcgtgcgaaagctgtgcgccacaaggaggattgctgcttcaccattctgtac
ggcacgcagttcgtcctcagcacgctcagcttggcaaccgactccagggaggaagcggcg
aagtggctgtccggcctgaaaatcctccaccaagaagcgctgagcgcatccaccccaagc
atgatcgagagttggctgagaaaacagatttattctgtggatcaaaccagaagaaacagc
attggcctccgggagatgaaggccattctgcccacagtgaacttcaaggtgaacagcgtg
aaactcctcaaggacaagttcatggaaatcagcacccacaaagacgagctcagcttcgaa
cagctgcatctcttctacaaaaagctgatgttcgagcagcagaaatcgatacttgatgaa
ttcaagaaggattcctctgtgttcattctggggagcacggaccggctggaggcctccgtg
gtgtacctgcaggacttccagaggttcctcctgcacgaacagcaggagccctgggctcag
gatataaacaaagtccgggagcggatgaccaggttcatcgatgacaccatgagagagact
gtggagcctttcctgtttgtggatgagaagtggactcgccactactgtgccattgccgac
gccaaactgtccttcagcgacgacatcgaacagaacgtggaggaggagccaccccaggat
actccccccacggagctgcacctaggggaaaaatggttccacaagaaggtggagaagagg
acgagcgcggagaagctgatgcagcagtactgcctggagacgggggccaaggatggcacc
ttcctggtgcgggagagcgagacctacccggacaactacacgctgtccttctggcgctca
ggccgcgtgcagcactgcctcatccgctccactgtggagggcggggccaagaagtactac
ctgaccgacaacctcaccttccccagcatctacgcgctggtccagcactaccgcgaggcg
cacctgcgctgcgcagagttcgagctgaggctcacggacgccgtgcccaaccccaacccg
cacgagtccaagccgtggtactacggccagctgagccggggcgaggcggaggacatgctc
atgcgggtcccccgcgacggggccttcctcatccggcggcgggaggggaccgactcctac
gccatcaccttcagggcccggggcaaggtgaagcactgccgtatcagccgggacggccgg
cactttgtgctgggcacctccgcctacttcgagagcctggtggagctggtcagctactac
gagaagcacgctctgtaccgcaagatgaggctgcgctaccccgtgacgcccgagctgctg
gagcgctacagcgtggtaggcacagcccgccccggtccccggggcctctgcgggtccccc
atccccccaggtggacgggggtccaggctgctccagttcctcacctacctgttctcccgg
gagaacagcatctgggacgacaagtatgacgcggtggacatgcaggacatgaacaacccc
ctgtcccactactggatctcctcctcccacaacacgtacctcaccggggaccagctccgc
agcgagtcgtccaccgaggcctacgtgcgctgcctgcgtctgggctgccgctgcatcgag
tgtgagtgtcggccatgcagctccgggggtcccagcccccgccttcgggatgtcccaggg
cctgggcccctcagggaggagactggcggggccctgggagccccggggctggaatgccat
gtttcttcacagattatggaagataatcccctaggatctctctgcagagggatcctggac
ctgaataactacaacgttgtaaaagccccacatggaaagaaccagaaacctttcgtcttc
atcctggagcccaagaagcagggggaccccccggtggagttcgccgcggacagcgtggag
gagctcttcgagtggttccagagcattcgacagatcacctggaagatcgacaccaaggag
aacaacatgaagtactgggagaagaaccagtccatcgccattgagctctctgacttggtt
gtctactgcaagccgaccagcaaaaccaaggacaatctagagaaccccgacttccgagag
atccgctcctttgtggagaccaaggcggacagcatggtgcggcagaagccccgggagctg
ctgcggtacaaccagaagggcctgacgcgcgtctaccccaaaggacagcgcgtggactcc
tccaactacgacccgttccgcctgtggctgtgcggcgcccagatggtggccctcaacttc
cagaccgcagacaaatacatgcagatgaaccacgcgctgttctcgctcaatggccggaca
ggctacgtcctgcagcccgagagcatgcgcggggagaagtacgacccgctaccgcccgag
tcgcagaggagggtcgtgatgacgctcactgtcaaggtccttggcgctcgccacctcccc
aagcttgggcgaagtatcgcttgccccttcgtggaggtggagatctgtggggcggagtac
gacaacaataagtttaagacaacggtcgtgaatgacaatggcctcagccctgtgtgggct
cccacccaggagaaggtgacctttgagatttatgaccccagcctggccttcctgcgcttc
gtggtctacgaagaagacatgttcagcgaccccaacttcctggcccacgccacctacccc
atcaaaggcatcaagtcagggttcagatccgtgcctctgaagaatgggtacagcgaggac
atcgagctggcgtccctcctggttttctgtgagatgcggcccgtcttggagtgtgaggag
gagctgtattcctcctgtcgccagctgcgaaggaggcaggaagaactcaacaaccagctc
ttcttatacgacacacaccagaacctgcgtaatgccaaccgagatgctctggtgaaggag
ttcaacgtcaacgagaaccagctccagctgtaccaggacaggtgcaaccggaggctgcga
gagaagagggtcagcaacagcaagttttactcatag
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