Dipodomys ordii (Ord's kangaroo rat): 105986795 Help Entry 105986795         CDS       T07834                                  Symbol Sos1 Name (RefSeq) son of sevenless homolog 1   KO K03099   son of sevenless Organism dord  Dipodomys ordii (Ord's kangaroo rat) Pathway dord01521   EGFR tyrosine kinase inhibitor resistance dord01522   Endocrine resistance dord04010   MAPK signaling pathway dord04012   ErbB signaling pathway dord04014   Ras signaling pathway dord04062   Chemokine signaling pathway dord04068   FoxO signaling pathway dord04072   Phospholipase D signaling pathway dord04150   mTOR signaling pathway dord04151   PI3K-Akt signaling pathway dord04510   Focal adhesion dord04540   Gap junction dord04630   JAK-STAT signaling pathway dord04650   Natural killer cell mediated cytotoxicity dord04660   T cell receptor signaling pathway dord04662   B cell receptor signaling pathway dord04664   Fc epsilon RI signaling pathway dord04714   Thermogenesis dord04722   Neurotrophin signaling pathway dord04810   Regulation of actin cytoskeleton dord04910   Insulin signaling pathway dord04912   GnRH signaling pathway dord04915   Estrogen signaling pathway dord04917   Prolactin signaling pathway dord04926   Relaxin signaling pathway dord04935   Growth hormone synthesis, secretion and action dord05034   Alcoholism dord05160   Hepatitis C dord05161   Hepatitis B dord05163   Human cytomegalovirus infection dord05165   Human papillomavirus infection dord05200   Pathways in cancer dord05205   Proteoglycans in cancer dord05206   MicroRNAs in cancer dord05207   Chemical carcinogenesis - receptor activation dord05208   Chemical carcinogenesis - reactive oxygen species dord05210   Colorectal cancer dord05211   Renal cell carcinoma dord05213   Endometrial cancer dord05214   Glioma dord05215   Prostate cancer dord05220   Chronic myeloid leukemia dord05221   Acute myeloid leukemia dord05223   Non-small cell lung cancer dord05224   Breast cancer dord05225   Hepatocellular carcinoma dord05226   Gastric cancer dord05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:dord00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105986795 (Sos1)    04012 ErbB signaling pathway     105986795 (Sos1)    04014 Ras signaling pathway     105986795 (Sos1)    04630 JAK-STAT signaling pathway     105986795 (Sos1)    04068 FoxO signaling pathway     105986795 (Sos1)    04072 Phospholipase D signaling pathway     105986795 (Sos1)    04151 PI3K-Akt signaling pathway     105986795 (Sos1)    04150 mTOR signaling pathway     105986795 (Sos1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     105986795 (Sos1)    04540 Gap junction     105986795 (Sos1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     105986795 (Sos1)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     105986795 (Sos1)    04660 T cell receptor signaling pathway     105986795 (Sos1)    04662 B cell receptor signaling pathway     105986795 (Sos1)    04664 Fc epsilon RI signaling pathway     105986795 (Sos1)    04062 Chemokine signaling pathway     105986795 (Sos1)   09152 Endocrine system    04910 Insulin signaling pathway     105986795 (Sos1)    04912 GnRH signaling pathway     105986795 (Sos1)    04915 Estrogen signaling pathway     105986795 (Sos1)    04917 Prolactin signaling pathway     105986795 (Sos1)    04926 Relaxin signaling pathway     105986795 (Sos1)    04935 Growth hormone synthesis, secretion and action     105986795 (Sos1)   09156 Nervous system    04722 Neurotrophin signaling pathway     105986795 (Sos1)   09159 Environmental adaptation    04714 Thermogenesis     105986795 (Sos1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105986795 (Sos1)    05206 MicroRNAs in cancer     105986795 (Sos1)    05205 Proteoglycans in cancer     105986795 (Sos1)    05207 Chemical carcinogenesis - receptor activation     105986795 (Sos1)    05208 Chemical carcinogenesis - reactive oxygen species     105986795 (Sos1)    05231 Choline metabolism in cancer     105986795 (Sos1)   09162 Cancer: specific types    05210 Colorectal cancer     105986795 (Sos1)    05225 Hepatocellular carcinoma     105986795 (Sos1)    05226 Gastric cancer     105986795 (Sos1)    05214 Glioma     105986795 (Sos1)    05221 Acute myeloid leukemia     105986795 (Sos1)    05220 Chronic myeloid leukemia     105986795 (Sos1)    05211 Renal cell carcinoma     105986795 (Sos1)    05215 Prostate cancer     105986795 (Sos1)    05213 Endometrial cancer     105986795 (Sos1)    05224 Breast cancer     105986795 (Sos1)    05223 Non-small cell lung cancer     105986795 (Sos1)   09172 Infectious disease: viral    05161 Hepatitis B     105986795 (Sos1)    05160 Hepatitis C     105986795 (Sos1)    05163 Human cytomegalovirus infection     105986795 (Sos1)    05165 Human papillomavirus infection     105986795 (Sos1)   09165 Substance dependence    05034 Alcoholism     105986795 (Sos1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105986795 (Sos1)    01522 Endocrine resistance     105986795 (Sos1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH PH_10 PH_19 IQ_SEC7_PH RHG20_PH Takusan Motif Other DBs NCBI-GeneID:  105986795 NCBI-ProteinID:  XP_012873352 Ensembl:  ENSDORG00000002340 UniProt:  A0A1S3FBM9 LinkDB All DBs Position Unknown AA seq 1355 aa AA seqDB search MLADEYLLEKNYEMDSILGLETVVGRIYTVRVAMYGKIHRTLVDCPVCNDRQVQGQVHPT LESNDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKR KRRNPTLPVEKIHPLLREVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEIT KQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRE LNLIIKVFREPFISNSKLFSANDVENIFSRIVDIHELSIKLLGHIEDTVEMTDEGSPHPL VGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYV LPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKR RLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLIRVGAKHE RHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIIL KDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFA EPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQ ELLSLVIERFEIPEPEPTEADRMAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVE HHFYDFERDADLLQRMEDFIGTVKGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSP PTVEWHISRPGHTETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINS PNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAM NSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNIL KTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMG SSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQ EPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSD TVFIPVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDS PPAIPPRQPTSKVYSPRYSVSDRTSLSDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPL GKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQST SQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS NT seq 4068 nt NT seq  +upstreamnt  +downstreamnt atgctagcagatgagtacctcctggagaaaaattatgaaatggacagtattctggggcta gaaactgtggtaggacggatttacactgtgagggtagccatgtatggcaaaatacatagg actttggtggactgtcctgtctgcaatgacaggcaggtccaggggcaagttcatcctact cttgagtctaatgatgatgctcttcagtatgttgaagaattaattttgcaattattaaat atgttatgtcaagctcagccacgaagtgcttcagatgtagaggaacgtgttcaaaaaagt ttccctcatcctattgataaatgggcaatagctgatgcacaatcagctattgaaaagagg aagcgaagaaatccaactctcccagtagaaaaaattcatcctttattaagggaggtccta ggttataaaattgaccaccaggtttctgtttacatagtagcagtgttagaatacatttct gcagacattttaaagctggttgggaattatgtaagaaatatacggcattatgaaattaca aaacaagatattaaagtggcaatgtgtgctgacaaggtattgatggatatgtttcatcaa gatgtagaagatataaatatattatctttaactgatgaagaaccttccacctcaggagaa caaacttactatgatttagttaaagcatttatggcagaaattcgacaatatataagagaa ctaaatcttataataaaagtttttagagagcccttcatctccaattccaaattgttttct gctaatgatgtagaaaatatatttagtcgaatagtagatattcatgaacttagtataaaa ttgctgggccacatagaagatactgttgaaatgacagatgaaggcagtccccacccatta gttggaagctgctttgaagatcttgcagaagaactggcatttgatccatatgaatcatac gctcgagatattttacgaccaggttttcatgatcgtttcctcagtcagttatcaaagcct ggggcagcactttatttgcagtcaataggcgaaggtttcaaagaagctgttcaatatgtt ttacccaggctactgctagcccctgtttaccactgtctgcattactttgaacttctgaag cagttagaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataaca gctttgcttaatgttcaaagtggtatggaaaaaatatgttctaaaagtcttgctaaacga agactgagtgaatctgcgtgtcgtttttatagtcaacaaatgaaggggaaacaactagca atcaagaaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattgga cagtgttgcaatgaatttataatggaaggaactcttatacgtgtaggagcaaaacatgag agacacatatttctctttgatggcttaatgatttgctgtaaatcaaatcacgggcagcca agacttcctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgcgaaag gtacaaattaatgataaagatgacaccaatgaatacaagcatgcttttgaaataattcta aaagatgaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatg gcagcattgatatctttacagtatcggagtacactggaaaggatgcttgatgtaacaatg ctacaggaagagaaggaggagcaaatgaggctgcctagtgctgatgtatatagatttgca gagccagactctgaagagaatattatatttgaagagaacatgcagcccaaggctggaatt ccaattatcaaagcaggaactgttattaaacttatagaaagacttacataccatatgtat gcagatcccaattttgttcggacatttcttacaacataccgatccttttgtaaacctcaa gaattattgagtcttgtaatagaaaggtttgaaattccagagcctgagccaacagaagcc gatcggatggctatagagaatggagatcaacccctgagtgcagaactaaaaaggtttaga aaagaatatatacagcctgtgcaactgcgggtgttaaatgtttgccggcactgggtagag caccacttttatgattttgaaagagatgcagatcttttgcaacgtatggaggactttatt ggaacagtaaaaggtaaagcaatgaaaaaatgggttgaatccatcactaagataatccaa aggaaaaaaattgcaagagacaacggaccgggtcataatattacatttcagagttcacct cccactgttgagtggcacataagcagacctgggcacacagagacttttgacttactcact ttacacccaatagaaattgcccgtcaactcactttacttgaatcagatctatatagagct gtgcagccatcagaattagttggaagtgtatggacaaaagaagacaaagaaattaattct cctaatcttctgaaaatgatccgacacaccactaatctcactctctggtttgaaaaatgt attgtagaaactgaaaatttagaagaaagagtagcagtagtgagtcgaataattgagatt ctccaagtctttcaagagctgaataacttcaacggtgtccttgaagttgtgagcgctatg aattcctcacctgtttacagactagaccacacatttgagcaaataccaagtcggcaaaag aaaattttagaagaagctcatgagttgagtgaagatcattataagaaatatttagcaaaa ctcaggtctattaacccaccatgtgtgcctttctttggaatttatctcactaatatcttg aaaacagaagaaggcaaccctgaggtcctaaaaagacatggaaaagagctcataaacttt agcaaaaggaggaaagtagcagaaataacaggagaaatccagcagtaccaaaaccagcct tactgtttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccaatggga agtagcatggagaaagaatttacagattatctttttaacaaatccctagaaatagaacca cggaatcctaaacctctcccaagattcccaaaaaagtatagctatccactaaaatctcct ggtgttcgtccatcaaacccaagaccaggtacaatgaggcatcccacacctctgcaacaa gaaccaaggaagattagttacagtaggatccctgaaagtgaaacagaaagtacagcatct gcaccaaattctccaagaacaccgctcacacctcctcctgcttctggtgcttccagtacc acagatgtttgcagcgtgtttgattctgatcattcaagcccttttcactcaagcagcgat accgtctttatcccggttacactgccccatggcccaagatctgcgtcagtatcctctata agtttaaccaagggcacggatgaagtgcccgtccccccgcctgttcctccacgaagacga ccagaatctgccccagcggaatcttcgccatctaagattatgtctaagcacttggacagc cccccagccattcctcctaggcaacccacatccaaagtctattcaccacgatattcagtg tcagaccggacctctctctcagaccctcccgaaagccctcccttattaccaccacgagaa cctgtgaggacacccgatgtcttttcaagctcaccactacatctccaacctccccctttg ggcaaaaagagtgaccatggcaatgccttctttccaaacagcccttctccctttacaccg ccacctccccagaccccttctcctcatggcacgagaaggcatctgccatcaccaccattg acacaagaagtggacctccattccattgctgggccgcccgttcctccacgtcaaagcact tctcaacatatccctaaactccctccaaaaacttacaaaagggagcatacacacccatcc atgcacagagatggaccgccactgttggagaatgcccattcttcctga

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