Dipodomys ordii (Ord's kangaroo rat): 105987548 Help Entry 105987548         CDS       T07834                                  Symbol Adcy6 Name (RefSeq) adenylate cyclase type 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism dord  Dipodomys ordii (Ord's kangaroo rat) Pathway dord00230   Purine metabolism dord01100   Metabolic pathways dord01522   Endocrine resistance dord04015   Rap1 signaling pathway dord04022   cGMP-PKG signaling pathway dord04024   cAMP signaling pathway dord04062   Chemokine signaling pathway dord04072   Phospholipase D signaling pathway dord04081   Hormone signaling dord04082   Neuroactive ligand signaling dord04114   Oocyte meiosis dord04211   Longevity regulating pathway dord04213   Longevity regulating pathway - multiple species dord04261   Adrenergic signaling in cardiomyocytes dord04270   Vascular smooth muscle contraction dord04371   Apelin signaling pathway dord04540   Gap junction dord04611   Platelet activation dord04713   Circadian entrainment dord04714   Thermogenesis dord04723   Retrograde endocannabinoid signaling dord04724   Glutamatergic synapse dord04725   Cholinergic synapse dord04727   GABAergic synapse dord04742   Taste transduction dord04750   Inflammatory mediator regulation of TRP channels dord04911   Insulin secretion dord04912   GnRH signaling pathway dord04913   Ovarian steroidogenesis dord04914   Progesterone-mediated oocyte maturation dord04915   Estrogen signaling pathway dord04916   Melanogenesis dord04918   Thyroid hormone synthesis dord04921   Oxytocin signaling pathway dord04923   Regulation of lipolysis in adipocytes dord04924   Renin secretion dord04925   Aldosterone synthesis and secretion dord04926   Relaxin signaling pathway dord04927   Cortisol synthesis and secretion dord04928   Parathyroid hormone synthesis, secretion and action dord04934   Cushing syndrome dord04935   Growth hormone synthesis, secretion and action dord04961   Endocrine and other factor-regulated calcium reabsorption dord04962   Vasopressin-regulated water reabsorption dord04970   Salivary secretion dord04971   Gastric acid secretion dord04972   Pancreatic secretion dord04976   Bile secretion dord05032   Morphine addiction dord05163   Human cytomegalovirus infection dord05166   Human T-cell leukemia virus 1 infection dord05200   Pathways in cancer dord05207   Chemical carcinogenesis - receptor activation dord05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:dord00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105987548 (Adcy6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105987548 (Adcy6)    04371 Apelin signaling pathway     105987548 (Adcy6)    04072 Phospholipase D signaling pathway     105987548 (Adcy6)    04024 cAMP signaling pathway     105987548 (Adcy6)    04022 cGMP-PKG signaling pathway     105987548 (Adcy6)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     105987548 (Adcy6)    04081 Hormone signaling     105987548 (Adcy6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105987548 (Adcy6)   09144 Cellular community - eukaryotes    04540 Gap junction     105987548 (Adcy6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105987548 (Adcy6)    04062 Chemokine signaling pathway     105987548 (Adcy6)   09152 Endocrine system    04911 Insulin secretion     105987548 (Adcy6)    04923 Regulation of lipolysis in adipocytes     105987548 (Adcy6)    04912 GnRH signaling pathway     105987548 (Adcy6)    04913 Ovarian steroidogenesis     105987548 (Adcy6)    04915 Estrogen signaling pathway     105987548 (Adcy6)    04914 Progesterone-mediated oocyte maturation     105987548 (Adcy6)    04921 Oxytocin signaling pathway     105987548 (Adcy6)    04926 Relaxin signaling pathway     105987548 (Adcy6)    04935 Growth hormone synthesis, secretion and action     105987548 (Adcy6)    04918 Thyroid hormone synthesis     105987548 (Adcy6)    04928 Parathyroid hormone synthesis, secretion and action     105987548 (Adcy6)    04916 Melanogenesis     105987548 (Adcy6)    04924 Renin secretion     105987548 (Adcy6)    04925 Aldosterone synthesis and secretion     105987548 (Adcy6)    04927 Cortisol synthesis and secretion     105987548 (Adcy6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105987548 (Adcy6)    04270 Vascular smooth muscle contraction     105987548 (Adcy6)   09154 Digestive system    04970 Salivary secretion     105987548 (Adcy6)    04971 Gastric acid secretion     105987548 (Adcy6)    04972 Pancreatic secretion     105987548 (Adcy6)    04976 Bile secretion     105987548 (Adcy6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     105987548 (Adcy6)    04961 Endocrine and other factor-regulated calcium reabsorption     105987548 (Adcy6)   09156 Nervous system    04724 Glutamatergic synapse     105987548 (Adcy6)    04727 GABAergic synapse     105987548 (Adcy6)    04725 Cholinergic synapse     105987548 (Adcy6)    04723 Retrograde endocannabinoid signaling     105987548 (Adcy6)   09157 Sensory system    04742 Taste transduction     105987548 (Adcy6)    04750 Inflammatory mediator regulation of TRP channels     105987548 (Adcy6)   09149 Aging    04211 Longevity regulating pathway     105987548 (Adcy6)    04213 Longevity regulating pathway - multiple species     105987548 (Adcy6)   09159 Environmental adaptation    04713 Circadian entrainment     105987548 (Adcy6)    04714 Thermogenesis     105987548 (Adcy6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105987548 (Adcy6)    05207 Chemical carcinogenesis - receptor activation     105987548 (Adcy6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105987548 (Adcy6)    05163 Human cytomegalovirus infection     105987548 (Adcy6)   09165 Substance dependence    05032 Morphine addiction     105987548 (Adcy6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105987548 (Adcy6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105987548 (Adcy6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105987548 (Adcy6) Enzymes [BR:dord01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105987548 (Adcy6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  105987548 NCBI-ProteinID:  XP_012874282 Ensembl:  ENSDORG00000005171 UniProt:  A0A1S3FE84 LinkDB All DBs Position Unknown AA seq 1167 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRPRHGTRASGFCAPRYMSCLQDAEPPSPTPAAPA RCPWQDEAFIRRAGPGRGMELGLRAVALGFEDTEMTTAAGGAADVAPDAESRSGRSCWRR LVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPTSPHPAYV VLLVCAAILFVALMVVCNRHSFRQDSMWVVSYVVLGILAALQVGGALAANPHSPSAGLWV PVFFVYITYTLLPIRMRAAVLSGLGLSILHLILAWQLNRGDAFLWKQLGANVVLFFCTNV IGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTK KEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCL RIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVH CGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAY LKEQRIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQ MGIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKY SRKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYISIFLLLLVTVLICAVYSCG SLFPKVLQRLSRSIVRSRAHSTAVGIFSVLLVFISAIANMFTCNHTPIRTCAAQMLNLTP ADITTCHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGNMLLSLLASSVFLHISSIGKLAM TIVLGLIYLVLLLLGPAATIFDNYDLLLGVHGLASSNETFNELECPASGRVALKYMTPVI LLVFVLALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFL ARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISE ERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNF QMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGY QLECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3504 nt NT seq  +upstreamnt  +downstreamnt atgtcatggtttagtggcctcttggttcccaaagtggatgaacggaaaacagcttggggt gaacgcaatgggcagaagcgcccacgtcatgggactcgagccagtggcttctgtgcaccc cgctacatgagctgcctccaggatgcagaaccacccagccccactcctgcagctcctgca cggtgcccctggcaggatgaggcgttcattcggagggctggcccaggcaggggcatggag ctggggttgcgggctgtggccctgggctttgaggatactgagatgacaacagcagcaggt ggggcagctgacgtggcacctgatgcggaatccaggagtggacgatcttgctggcgccgt cttgtgcaggttttccagtcgaagcaattccgctcagccaagctggagcgcctataccaa cgctatttcttccagatgaaccagagtagcctgacgctgctgatggcagtgctggtgctg ctcaccgccgtgttgctagccttccatgctgcgcccacctctcctcatccagcctatgtg gtcctgctggtctgtgccgccatcctcttcgtggcgctcatggtggtgtgtaaccgacat agcttccgacaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcagct ctgcaggttggaggtgccctggcagccaacccacacagcccctcagcaggcctctgggtc cccgtgttctttgtctacatcacctacacactcctgcccatccgcatgcgggccgcagtg ctgagtggcctgggcctctccatccttcatttgatcttggcctggcaactcaaccgtgga gatgccttcctctggaagcagcttggtgctaacgtggtgctcttcttctgcaccaatgtc attggcatctgcacacactaccctgctgaagtgtcacaacgccaagcctttcaggagact cgcggttacatccaggctcgactgcacctgcagcatgagaatcggcagcaggagcggctg ctactgtcagtgttgccccagcatgttgccatggagatgaaagaagatatcaacacaaaa aaagaagacatgatgttccacaagatctacatccagaagcacgacaatgtcagcatccta tttgcagacattgagggcttcaccagcctggcctcccagtgcactgcgcaggaactggtc atgaccttgaacgagctctttgcccggtttgacaagctggcagcggaaaaccattgtctg aggatcaagatcttaggtgactgttactactgtgtgtcagggctgccagaggctcgggca gaccatgcccactgctgtgtggagatgggggtggacatgatcgaggccatctcattagtg cgtgaggtgacaggcgtgaatgtcaacatgcgtgtgggcatccatagtggacgtgtgcac tgcggtgtccttggtctgcggaaatggcagttcgatgtgtggtccaacgatgtaaccctg gccaaccacatggaggcagggggccgggctggccgcatccacatcactcgggccacgctg cagtatctgaatggagactatgaggtggagccgggccgtggtggtgagcgcaacgcatat ctcaaggagcaacgcattgagaccttcctcatcctgggtgccagccagaaacggaaagag gaaaaggccatgctggccaagctacagaggacacgggccaattccatggaaggactgatg ccacgctgggttcctgatcgggccttctcccggaccaaggactccaaggcgttccgccag atgggcattgatgactccagcaaagacaaccgaggtgctcaagatgccctgaaccctgag gatgaggtcgatgagttcctgggccgtgccattgatgcccgcagcatcgatcagctgcgg aaggaccatgtgcgccggttcctgctcaccttccagagagaggatcttgaaaagaagtac tcacggaaggtggatccccgctttggagcctatgttgcctgtgccctgttggtcttctgt ttcatctgcttcatccagctcctcatcttcccacactccaccctgatgcttgggatctac ataagcatcttcctgctgctgctggtcactgtactgatctgtgctgtgtactcctgtggt tctctgttccccaaggtcctacagcgtctatcccggagcattgttcgctcccgggcacac agcacagcagttggcatcttctcagtcctgcttgtgttcatctctgccatcgccaacatg tttacctgtaaccacactcccatacggacctgtgcagcccagatgttgaatttaaccccc gctgacatcaccacctgccacctacaacagctcaattactctctgggcctggatgctccc ctgtgtgagggcaccgcacccacctgcagcttccctgagtacttcgtcgggaacatgctg cttagcctcttggccagctctgtcttcctgcacatcagcagcattggcaagttggccatg actattgtcttgggactcatctatttggtgctgcttctgctgggtccggcagctaccatc tttgacaactatgacctcctgcttggtgtccatggcttggcttcttccaatgagaccttt aatgagctggaatgcccagcttcagggagagtggccctcaaatacatgacccctgtgatt ctgctggtgtttgtgctggcactgtatctgcatgcccagcaggtggagtcaacagctcgc ctggacttcctctggaaactgcaggcaacaggggagaaggaagagatggaggagctccag gcttacaaccggcggcttctgcataacattctgcccaaggatgtggctgctcacttcctg gcccgggaacgccggaatgatgagctctactatcagtcgtgtgaatgcgtggctgttatg tttgcctccattgccaatttctctgagttctatgtggagttggaggcaaacaatgagggt gtcgagtgcctgcggctgctcaatgagatcatcgctgactttgatgagatcatcagtgag gagcggttccggcagctggagaagatcaagaccattggtagcacatacatggctgcatct gggctgaatgccagcacctatgatcaggtgggccgctcccacatcaccgccctggccgac tacgccatgcggctcatggagcagatgaagcacatcaatgaacactccttcaataatttc cagatgaagattggactgaacatgggcccagttgtagcaggcgtcattggggctcggaaa ccacagtatgacatctgggggaacacagtgaatgtctctagtcgtatggacagcacaggg gttcctgatcgaatacaggtgaccacggacctgtaccaggttctagctgccaagggctac caactggagtgtcgaggggtggtcaaggtaaagggcaagggagagatgaccacctacttc ctcaatgggggccctagcagttag

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