Dipodomys ordii (Ord's kangaroo rat): 105988847 Help Entry 105988847         CDS       T07834                                  Symbol Jak1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism dord  Dipodomys ordii (Ord's kangaroo rat) Pathway dord01521   EGFR tyrosine kinase inhibitor resistance dord04151   PI3K-Akt signaling pathway dord04217   Necroptosis dord04380   Osteoclast differentiation dord04550   Signaling pathways regulating pluripotency of stem cells dord04620   Toll-like receptor signaling pathway dord04621   NOD-like receptor signaling pathway dord04630   JAK-STAT signaling pathway dord04658   Th1 and Th2 cell differentiation dord04659   Th17 cell differentiation dord05140   Leishmaniasis dord05145   Toxoplasmosis dord05152   Tuberculosis dord05160   Hepatitis C dord05161   Hepatitis B dord05162   Measles dord05163   Human cytomegalovirus infection dord05164   Influenza A dord05165   Human papillomavirus infection dord05166   Human T-cell leukemia virus 1 infection dord05167   Kaposi sarcoma-associated herpesvirus infection dord05168   Herpes simplex virus 1 infection dord05169   Epstein-Barr virus infection dord05171   Coronavirus disease - COVID-19 dord05200   Pathways in cancer dord05203   Viral carcinogenesis dord05212   Pancreatic cancer dord05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:dord00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105988847 (Jak1)    04151 PI3K-Akt signaling pathway     105988847 (Jak1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     105988847 (Jak1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     105988847 (Jak1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105988847 (Jak1)    04621 NOD-like receptor signaling pathway     105988847 (Jak1)    04658 Th1 and Th2 cell differentiation     105988847 (Jak1)    04659 Th17 cell differentiation     105988847 (Jak1)   09158 Development and regeneration    04380 Osteoclast differentiation     105988847 (Jak1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105988847 (Jak1)    05203 Viral carcinogenesis     105988847 (Jak1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     105988847 (Jak1)   09162 Cancer: specific types    05212 Pancreatic cancer     105988847 (Jak1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105988847 (Jak1)    05161 Hepatitis B     105988847 (Jak1)    05160 Hepatitis C     105988847 (Jak1)    05171 Coronavirus disease - COVID-19     105988847 (Jak1)    05164 Influenza A     105988847 (Jak1)    05162 Measles     105988847 (Jak1)    05168 Herpes simplex virus 1 infection     105988847 (Jak1)    05163 Human cytomegalovirus infection     105988847 (Jak1)    05167 Kaposi sarcoma-associated herpesvirus infection     105988847 (Jak1)    05169 Epstein-Barr virus infection     105988847 (Jak1)    05165 Human papillomavirus infection     105988847 (Jak1)   09171 Infectious disease: bacterial    05152 Tuberculosis     105988847 (Jak1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105988847 (Jak1)    05140 Leishmaniasis     105988847 (Jak1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105988847 (Jak1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dord01001]     105988847 (Jak1) Enzymes [BR:dord01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105988847 (Jak1) Protein kinases [BR:dord01001]  Non-receptor tyrosine kinases   JAK family [OT]    105988847 (Jak1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  105988847 NCBI-ProteinID:  XP_012876052 Ensembl:  ENSDORG00000013462 UniProt:  A0A1S3FJH6 LinkDB All DBs Position Unknown AA seq 1157 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEMNPVVPEPGVEVTFYLLDREPLRLGSGEYTAEEL CIRAAQECSISPLCHNLFALYDENTKLWYAPNHIITVNDKMSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLIKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMIKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENENW FHSNDSGNVLYYEVMVTGNLGIQWRQKPNAVPIEKEKNKLKRKKLENKLKKDEEKNKIRE EWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHH YLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTC FEKSEVLGGQKQFKNFQIEVQKGSYSLHGSDRRFPSLGELMSHLKKQILRTDNISFVLKR CCQPKPREISNLLVATKKAQEWQPVYSMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGTL VDYKDDEGTAEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVE NIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLL AREGIDSEIGPFIKLSDPGIPVSVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTT LWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIM RDINKLEEQNPDIVSERQPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTG EQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSG SLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDF GLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDS SPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPRNCPDEVYQLMRKCWELQPANRTTF QNLIEGFEALLRSMNNL NT seq 3474 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaacataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagactgagatgaatccggtagtccccgagccaggtgttgaagtgaccttt tatctgttggacagagagcccctccgactgggcagtggagagtacacggcggaggaactg tgcatcagggctgctcaggaatgcagtatctctcctttatgtcacaacctctttgcctta tacgatgagaacaccaaactctggtatgctccaaaccacatcatcactgtcaatgataag atgtcacttcggctccactaccgcatgaggttctacttcaccaactggcacgggaccaat gataatgaacagtctgtgtggcgacattctccaaagaagcagaaaaatggctatgagaaa aaaaaggttccagatgcaacccctctccttgatgcgagctcattagagtatctgtttgct cagggtcagtatgatttgatcaaatgcctagctcccattcgagaccctaagactgagcag gatggacatgatattgagaacgagtgcctcggaatggctgtcctggccatctcacactat gccatgataaagaagatgcagttgccagaacttcccaaggacatcagctacaagcgatat attccagaaacattgaataaatccatcagacaaagaaatcttctcaccagaatgagaata aataacgttttcaaggacttcctcaaggaatttaacaataagactatttgcgacagcagt gtgtccacacatgacctgaaggtgaaatacctggctaccttggaaacgctgacaaaacat tatggggctgaaatatttgagacttcaatgttactgatatcatcagaaaatgagaattgg tttcattcaaatgacagtggaaatgttctttactatgaagtaatggtgactggaaacctt ggaatccagtggcgacaaaaaccaaatgctgttcccattgaaaaggaaaaaaataagctg aagaggaagaaactggaaaataaacttaaaaaggatgaggagaaaaacaaaatcagggaa gagtggaataacttttcatacttccctgaaatcactcacattgtaataaaggagtctgta gtcagcattaacaagcaggacaacaaaaaaatggagctgaaactttcttcccatgaggag gccttgtcctttgtatccttggtagatggctatttccggctcacagcagatgcccaccat tacctctgcactgacgtggctcccccactgattgtccacaacatacagaatggctgtcat ggtccaatctgcacggaatatgccatcaataaactgcggcaagaaggtagtgaggagggg atgtatgtgctgaggtggagctgcactgactttgataacatcctcatgaccgtcacctgc tttgaaaagtctgaggtgctaggtggccaaaagcaattcaagaactttcagatcgaggta cagaagggcagctatagcctgcatggctcagaccgcagatttcccagcctgggagaactc atgagccatctcaagaagcagatcctacgcacagacaacatcagctttgtgctgaaacgc tgctgccaacccaaacctcgagaaatctccaatctgttggtggccacaaagaaagcacag gagtggcagcctgtctactccatgagccagctgagttttgatcggattcttaagaaagat attgtgcaaggtgagcaccttggcaggggcaccaggacacacatctactccgggaccctg gtggattacaaggatgatgaagggactgctgaggagaagagaataaaagtgatcctcaaa gtcttagaccctagccacagggacatttccctggccttctttgaggcagccagcatgatg agacaggtctcccacaaacacattgtgtacctctatggtgtgtgtgtccgagacgtggaa aatattatggtagaagaatttgtggagggggggcccctggatctcttcatgcaccggaaa agcgatgtccttaccacaccatggaagttcaaagttgctaaacagctggccagcgccctg agttacttggaggataaagacttggttcatggaaatgtgtgcaccaaaaatctccttctg gcccgagagggcatcgacagtgaaattggccctttcatcaaactcagcgaccctggcatc cctgtctctgtgctgtccaggcaagaatgcatagagcgaatcccatggattgctcctgag tgtgttgaagactctaagaacctgagtgtggctgccgacaagtggagctttggaaccaca ctgtgggaaatctgctacaatggcgagatacctttgaaagacaagaccttgattgagaaa gagagattctatgaaagccgttgcaggccagtgacaccatcctgcaaggaactagctgac cttatgacccgctgtatgaactatgaccccaatcagagacccttcttccgagccatcatg agggacattaacaagcttgaagagcagaatccagacattgtttcagaaagacaaccagca acggaggtggatcccacccattttgaaaagcgctttctgaagaggatccgtgatttggga gagggccactttgggaaggttgagctctgcaggtatgaccctgagggggacaatacagga gagcaggtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgacctg aagaaggaaatagaaatcctaaggaacctctatcacgagaacattgtgaagtacaaagga atctgcacagaagacggaggaaatggcatcaagctcattatggaatttctgccttcggga agccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacaacagctgaaa tatgccgttcagatttgtaaggggatggactatttgggttctcgacagtatgttcaccgg gacttagcagcaagaaacgtgcttgttgagagtgaacaccaagtgaaaattggagatttt ggtttaaccaaagcaattgaaactgataaggaatactacacagtcaaggatgaccgggac agtcctgtgttttggtatgctccagaatgcttaattcagtgtaaattttatattgcttct gacgtctggtcctttggagtgaccctgcatgagctgctcacttactgcgattcagattca agcccaatggccttgttcctgaaaatgatcggcccaactcacggccagatgacagttacg agacttgtgaacacactgaaagaagggaaacgcctgccgtgtccacgcaactgtcctgat gaggtttatcagcttatgagaaaatgctgggaattacaaccagccaatcggacaactttt cagaaccttattgaaggatttgaagcacttttaagaagcatgaataacctttaa

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