Dipodomys ordii (Ord's kangaroo rat): 105989470
Help
Entry
105989470 CDS
T07834
Symbol
Braf
Name
(RefSeq) serine/threonine-protein kinase B-raf
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord01521
EGFR tyrosine kinase inhibitor resistance
dord01522
Endocrine resistance
dord04010
MAPK signaling pathway
dord04012
ErbB signaling pathway
dord04015
Rap1 signaling pathway
dord04024
cAMP signaling pathway
dord04062
Chemokine signaling pathway
dord04068
FoxO signaling pathway
dord04150
mTOR signaling pathway
dord04270
Vascular smooth muscle contraction
dord04510
Focal adhesion
dord04650
Natural killer cell mediated cytotoxicity
dord04720
Long-term potentiation
dord04722
Neurotrophin signaling pathway
dord04726
Serotonergic synapse
dord04730
Long-term depression
dord04810
Regulation of actin cytoskeleton
dord04910
Insulin signaling pathway
dord04914
Progesterone-mediated oocyte maturation
dord04928
Parathyroid hormone synthesis, secretion and action
dord04934
Cushing syndrome
dord05010
Alzheimer disease
dord05022
Pathways of neurodegeneration - multiple diseases
dord05034
Alcoholism
dord05160
Hepatitis C
dord05161
Hepatitis B
dord05200
Pathways in cancer
dord05205
Proteoglycans in cancer
dord05208
Chemical carcinogenesis - reactive oxygen species
dord05210
Colorectal cancer
dord05211
Renal cell carcinoma
dord05212
Pancreatic cancer
dord05213
Endometrial cancer
dord05214
Glioma
dord05215
Prostate cancer
dord05216
Thyroid cancer
dord05218
Melanoma
dord05219
Bladder cancer
dord05220
Chronic myeloid leukemia
dord05221
Acute myeloid leukemia
dord05223
Non-small cell lung cancer
dord05224
Breast cancer
dord05225
Hepatocellular carcinoma
dord05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105989470 (Braf)
04012 ErbB signaling pathway
105989470 (Braf)
04015 Rap1 signaling pathway
105989470 (Braf)
04068 FoxO signaling pathway
105989470 (Braf)
04024 cAMP signaling pathway
105989470 (Braf)
04150 mTOR signaling pathway
105989470 (Braf)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
105989470 (Braf)
09142 Cell motility
04810 Regulation of actin cytoskeleton
105989470 (Braf)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
105989470 (Braf)
04062 Chemokine signaling pathway
105989470 (Braf)
09152 Endocrine system
04910 Insulin signaling pathway
105989470 (Braf)
04914 Progesterone-mediated oocyte maturation
105989470 (Braf)
04928 Parathyroid hormone synthesis, secretion and action
105989470 (Braf)
09153 Circulatory system
04270 Vascular smooth muscle contraction
105989470 (Braf)
09156 Nervous system
04726 Serotonergic synapse
105989470 (Braf)
04720 Long-term potentiation
105989470 (Braf)
04730 Long-term depression
105989470 (Braf)
04722 Neurotrophin signaling pathway
105989470 (Braf)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105989470 (Braf)
05205 Proteoglycans in cancer
105989470 (Braf)
05208 Chemical carcinogenesis - reactive oxygen species
105989470 (Braf)
09162 Cancer: specific types
05210 Colorectal cancer
105989470 (Braf)
05212 Pancreatic cancer
105989470 (Braf)
05225 Hepatocellular carcinoma
105989470 (Braf)
05226 Gastric cancer
105989470 (Braf)
05214 Glioma
105989470 (Braf)
05216 Thyroid cancer
105989470 (Braf)
05221 Acute myeloid leukemia
105989470 (Braf)
05220 Chronic myeloid leukemia
105989470 (Braf)
05218 Melanoma
105989470 (Braf)
05211 Renal cell carcinoma
105989470 (Braf)
05219 Bladder cancer
105989470 (Braf)
05215 Prostate cancer
105989470 (Braf)
05213 Endometrial cancer
105989470 (Braf)
05224 Breast cancer
105989470 (Braf)
05223 Non-small cell lung cancer
105989470 (Braf)
09172 Infectious disease: viral
05161 Hepatitis B
105989470 (Braf)
05160 Hepatitis C
105989470 (Braf)
09164 Neurodegenerative disease
05010 Alzheimer disease
105989470 (Braf)
05022 Pathways of neurodegeneration - multiple diseases
105989470 (Braf)
09165 Substance dependence
05034 Alcoholism
105989470 (Braf)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
105989470 (Braf)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105989470 (Braf)
01522 Endocrine resistance
105989470 (Braf)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dord01001
]
105989470 (Braf)
Enzymes [BR:
dord01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105989470 (Braf)
Protein kinases [BR:
dord01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
105989470 (Braf)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
C1_2
ABC1
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
105989470
NCBI-ProteinID:
XP_012877017
Ensembl:
ENSDORG00000009732
UniProt:
A0A1S3FMB4
LinkDB
All DBs
Position
Unknown
AA seq
724 aa
AA seq
DB search
MESLKHADYQLGLCQGSKTRSYLSNNQQMHGSAVWNIKQMIKLTQEHIEALLDKFGGEHN
PPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPS
SLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPE
CCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRK
LLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEETSLTETVLT
SGSSPSAPTSDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINT
IEPVNIDDLIRDQGFRGDGGKANLFTVTFLCTFKTPLNQLMRCLRKYQSRTPSPLLHSVP
SEIVFDFEPGPVFRGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKP
QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIF
LHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFG
IVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDE
RPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEF
AAFK
NT seq
2175 nt
NT seq
+upstream
nt +downstream
nt
atggagagcctaaagcatgcagattatcaactaggcttgtgtcagggcagtaaaacaaga
tcctatctttcaaataaccagcagatgcatggttcagcagtgtggaatatcaaacaaatg
attaagttgacacaagaacatatagaggccctgttggacaaatttggtggggagcataat
ccaccatcaatatacctggaggcctatgaagaatacaccagcaagctagatgccctccaa
caaagagaacaacagttattggaatccctgggaaacggaactgatttttctgtttctagc
tctgcatcaatggacactgttacatcttcttcttcttctagcctttcagtgctaccttca
tctctttcagtttttcaaaatcccacagatgtatctcggagcaaccccaagtcaccacaa
aaacctattgttagagtcttcctgcccaacaaacagaggacagtggtacctgcaagatgt
ggagttacagtccgagacagcctaaagaaagcactcatgatgagaggtcttatcccagag
tgctgtgctgtttacagaattcaggatggagagaagaagcctattggttgggatactgat
atttcctggcttactggggaggagttgcatgtagaagtgttggagaatgttccgctcaca
acacacaactttgtacggaaaacttttttcaccttagctttttgtgacttttgtcgaaag
ctgcttttccaaggtttccgctgtcaaacatgtggttataaatttcaccagcgttgtagt
acagaagttccactgatgtgtgttaattatgaccaacttgatttgctgtttgtctccaag
ttctttgaacatcacccaataccacaggaggagacctccttaacagagactgtccttaca
tctggatcatccccttctgcacccacctcagattctattgggccccaaattctcaccagt
ccatctccttcaaaatccattccaattccacagcccttccgaccagcagatgaagatcat
agaaatcagtttgggcaacgggaccggtcctcatcagctcctaatgtgcatataaacaca
atagaacctgtcaatattgatgatttgattagagatcaagggtttcgtggtgatggaggt
aaagctaatctcttcactgtgaccttcttgtgtaccttcaaaacccccttgaaccagctg
atgcgctgtcttcggaaataccaatcccggactcccagccccctcctacattctgtcccc
agtgaaatagtgtttgattttgagcctggcccagtgttcagaggtgatgtagcagtgaaa
atgttgaatgtgacagcacctacacctcaacagttacaggccttcaaaaatgaagtagga
gtactcaggaaaacacgacatgtaaacatcctactcttcatgggctattccacaaagcca
cagctggctattgttacccagtggtgcgagggctccagcttatatcaccacctgcacatc
attgagaccaaatttgagatgatcaaacttatagatattgcacggcagactgcacagggc
atggattatttacacgccaagtcaatcatccacagagacctcaagagtaataatatattt
cttcatgaagacctcacggtaaaaataggtgattttggtctagccacagtgaaatctcga
tggagtgggtcccatcagtttgaacagttgtctggatctattttgtggatggcaccagaa
gtaatcagaatgcaagataaaaacccatacagctttcagtcagatgtgtatgcatttgga
attgttttgtatgaattgatgactggccagttaccttattcaaatatcaacaacagggac
cagataatttttatggtgggacgaggatacctgtctccagatctcagtaaagtgcggagc
aactgtccgaaagccatgaagagattaatggcagagtgcctcaaaaagaagagagatgag
agaccgctctttccccaaattctcgcctctattgagctgttggcccgctcattgccaaaa
attcaccgtagtgcatcagaaccctccttgaaccgggctggttttcagacagaggatttt
agtctatatgcttgtgcttctccaaaaacacccattcaggcagggggctatggagaattt
gcagccttcaagtag
DBGET
integrated database retrieval system
